CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : CodonNum = 435 & Codon = ctG

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4435L435LL3198LsynctActG210303310.01573949857-9859

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4435L435LctActG33121030All0.000063
ORF1ab/nsp4435L435LctActG522783B.1.1.70.000047
ORF1ab/nsp4435L435LctActG101245AY.40.000016
ORF1ab/nsp4435L435LctActG15775B.1.617.20.000056
ORF1ab/nsp4435L435LctActG1262AY.460.000104
ORF1ab/nsp4435L435LctActG70230AY.30.000696
ORF1ab/nsp4435L435LctActG11229B.10.000101
ORF1ab/nsp4435L435LctActG1222AY.1030.000006
ORF1ab/nsp4435L435LctActG1202B.1.5260.000024
ORF1ab/nsp4435L435LctActG5172B.1.20.000044
ORF1ab/nsp4435L435LctActG2171AY.430.000009
ORF1ab/nsp4435L435LctActG1164B.1.5950.000261
ORF1ab/nsp4435L435LctActG30163AY.440.000183
ORF1ab/nsp4435L435LctActG3162P.10.000047
ORF1ab/nsp4435L435LctActG4102AY.250.000024
ORF1ab/nsp4435L435LctActG196B.1.1600.000031
ORF1ab/nsp4435L435LctActG188B.1.10.000018
ORF1ab/nsp4435L435LctActG282AY.260.000057
ORF1ab/nsp4435L435LctActG471AY.4.20.000087
ORF1ab/nsp4435L435LctActG470B.1.1770.000053
ORF1ab/nsp4435L435LctActG259AY.90.000135
ORF1ab/nsp4435L435LctActG240AY.290.000032
ORF1ab/nsp4435L435LctActG130AY.390.000025
ORF1ab/nsp4435L435LctActG129B.1.6210.000089
ORF1ab/nsp4435L435LctActG127AY.1200.000037
ORF1ab/nsp4435L435LctActG226P.1.150.000465
ORF1ab/nsp4435L435LctActG723AY.1190.000247
ORF1ab/nsp4435L435LctActG122AY.1000.000046
ORF1ab/nsp4435L435LctActG119AY.50.000021
ORF1ab/nsp4435L435LctActG219AY.750.000112
ORF1ab/nsp4435L435LctActG119B.1.1.5190.00004
ORF1ab/nsp4435L435LctActG117AY.116.10.000311
ORF1ab/nsp4435L435LctActG1517B.1.6090.007191
ORF1ab/nsp4435L435LctActG315B.1.360.000438
ORF1ab/nsp4435L435LctActG512AY.60.000206
ORF1ab/nsp4435L435LctActG512B.1.1.2220.00102
ORF1ab/nsp4435L435LctActG1112B.1.5250.001245
ORF1ab/nsp4435L435LctActG311AY.9.20.00011
ORF1ab/nsp4435L435LctActG110P.1.120.000484
ORF1ab/nsp4435L435LctActG19AY.200.000039
ORF1ab/nsp4435L435LctActG19AY.540.000095
ORF1ab/nsp4435L435LctActG59Q.10.000632
ORF1ab/nsp4435L435LctActG58AY.4.2.10.000745
ORF1ab/nsp4435L435LctActG48B0.000511
ORF1ab/nsp4435L435LctActG27B.1.1.3720.001377
ORF1ab/nsp4435L435LctActG77B.1.177.720.023729
ORF1ab/nsp4435L435LctActG26AY.360.000296
ORF1ab/nsp4435L435LctActG26B.1.1.280.000622
ORF1ab/nsp4435L435LctActG15AY.46.40.000165
ORF1ab/nsp4435L435LctActG15B.1.160.140.002119
ORF1ab/nsp4435L435LctActG14AY.1060.000335
ORF1ab/nsp4435L435LctActG14AY.16.10.00047
ORF1ab/nsp4435L435LctActG13AY.680.000274
ORF1ab/nsp4435L435LctActG13B.1.1.5280.004808
ORF1ab/nsp4435L435LctActG13P.1.160.000374
ORF1ab/nsp4435L435LctActG22AE.80.000978
ORF1ab/nsp4435L435LctActG12B.1.1.3690.000446
ORF1ab/nsp4435L435LctActG22B.1.214.30.014286
ORF1ab/nsp4435L435LctActG12B.1.4700.001404
ORF1ab/nsp4435L435LctActG11A0.000387
ORF1ab/nsp4435L435LctActG11AY.4.40.000409
ORF1ab/nsp4435L435LctActG11B.1.177.570.000281
ORF1ab/nsp4435L435LctActG11B.1.258.140.00098
ORF1ab/nsp4435L435LctActG11B.1.3750.00082
ORF1ab/nsp4435L435LctActG11B.1.4430.004673

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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