CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : CodonNum = 418

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4418C418CC3181CsyntgCtgT1070107019806-9808
ORF1ab/nsp4418C418delC3181deldelTGC---10910919806-9808
ORF1ab/nsp4418C418FC3181FnonsyntGctTc83660.7951819806-9808
ORF1ab/nsp4418C418FC3181FnonsyntGCtTT83170.2048199806-9808
ORF1ab/nsp4418C418RC3181RnonsynTgcCgc62610.9838719806-9808
ORF1ab/nsp4418C418RC3181RnonsynTgCAgG6210.0161299806-9808
ORF1ab/nsp4418C418GC3181GnonsynTgcGgc11100.9090919806-9808
ORF1ab/nsp4418C418GC3181GnonsynTgCGgG1110.09090919806-9808
ORF1ab/nsp4418C418SC3181SnonsyntGctCc1060.69806-9808
ORF1ab/nsp4418C418SC3181SnonsynTgcAgc1030.39806-9808
ORF1ab/nsp4418C418SC3181SnonsynTgCAgT1010.19806-9808
ORF1ab/nsp4418C418YC3181YnonsyntGctAc980.8888899806-9808
ORF1ab/nsp4418C418YC3181YnonsyntGCtAT910.1111119806-9808
ORF1ab/nsp4418C418del1C3181del1deltGct-c620.3333339806-9808
ORF1ab/nsp4418C418del1C3181del1deltgCtg-620.3333339806-9808
ORF1ab/nsp4418C418del1C3181del1deltGCtA-610.1666679806-9808
ORF1ab/nsp4418C418del1C3181del1delTgc-gc610.1666679806-9808
ORF1ab/nsp4418C418XC3181XnonsyntgCtgA430.759806-9808
ORF1ab/nsp4418C418XC3181XnonsyntGCtAG410.259806-9808
ORF1ab/nsp4418C418WC3181WnonsyntgCtgG3319806-9808
ORF1ab/nsp4418C418HC3181HnonsynTGcCAc2219806-9808
ORF1ab/nsp4418C418NC3181NnonsynTGCAAT210.59806-9808
ORF1ab/nsp4418C418KC3181KnonsynTGCAAG210.59806-9808
ORF1ab/nsp4418C418NC3181NnonsynTGcAAc210.59806-9808
ORF1ab/nsp4418C418KC3181KnonsynTGCAAA210.59806-9808
ORF1ab/nsp4418C418del2C3181del2delTGc--c1119806-9808
ORF1ab/nsp4418C418VC3181VnonsynTGcGTc1119806-9808
ORF1ab/nsp4418C418LC3181LnonsynTGCCTT1119806-9808

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4418C418CtgCtgT10701070All0.000205
ORF1ab/nsp4418C418CtgCtgT181181B.1.1.70.000162
ORF1ab/nsp4418C418CtgCtgT114114B.1.3980.339286
ORF1ab/nsp4418C418delTGC---109109All0.000021
ORF1ab/nsp4418C418CtgCtgT104104C.30.10.697987
ORF1ab/nsp4418C418CtgCtgT9999AY.40.000154
ORF1ab/nsp4418C418FtGctTc6683All0.000013
ORF1ab/nsp4418C418FtGCtTT1783All0.000003
ORF1ab/nsp4418C418CtgCtgT6767B.1.3510.001992
ORF1ab/nsp4418C418RTgcCgc6162All0.000012
ORF1ab/nsp4418C418RTgCAgG162All0
ORF1ab/nsp4418C418delTGC---4444B.1.1.70.000039
ORF1ab/nsp4418C418CtgCtgT4141B.10.000376
ORF1ab/nsp4418C418CtgCtgT3838AY.30.000378
ORF1ab/nsp4418C418CtgCtgT3131AY.430.000137
ORF1ab/nsp4418C418CtgCtgT3030AY.680.008212
ORF1ab/nsp4418C418CtgCtgT2828AY.50.000578
ORF1ab/nsp4418C418CtgCtgT2828B.1.617.20.000105
ORF1ab/nsp4418C418RTgcCgc2424AY.40.000037
ORF1ab/nsp4418C418CtgCtgT2121AY.1020.000557
ORF1ab/nsp4418C418CtgCtgT1818AY.440.00011
ORF1ab/nsp4418C418CtgCtgT1414P.10.000221
ORF1ab/nsp4418C418CtgCtgT1313B.1.4290.000306
ORF1ab/nsp4418C418CtgCtgT1313B.1.930.012138
ORF1ab/nsp4418C418FtGctTc1212AY.40.000019
ORF1ab/nsp4418C418GTgcGgc1011All0.000002
ORF1ab/nsp4418C418GTgCGgG111All0
ORF1ab/nsp4418C418CtgCtgT1111B.1.1770.000145
ORF1ab/nsp4418C418StGctCc610All0.000001
ORF1ab/nsp4418C418STgcAgc310All0.000001
ORF1ab/nsp4418C418STgCAgT110All0
ORF1ab/nsp4418C418FtGctTc510B.1.1.70.000004
ORF1ab/nsp4418C418FtGCtTT510B.1.1.70.000004
ORF1ab/nsp4418C418YtGctAc89All0.000002
ORF1ab/nsp4418C418YtGCtAT19All0
ORF1ab/nsp4418C418CtgCtgT99AY.1030.000056
ORF1ab/nsp4418C418CtgCtgT99AY.250.000054
ORF1ab/nsp4418C418FtGctTc99AY.30.00009
ORF1ab/nsp4418C418FtGctTc99AY.4.2.10.001341
ORF1ab/nsp4418C418CtgCtgT99B.1.10.000163
ORF1ab/nsp4418C418CtgCtgT99B.1.20.000079
ORF1ab/nsp4418C418CtgCtgT99B.1.6370.000658
ORF1ab/nsp4418C418FtGCtTT880.444444
ORF1ab/nsp4418C418CtgCtgT88AY.98.10.000387
ORF1ab/nsp4418C418CtgCtgT88B.1.1.3160.007401
ORF1ab/nsp4418C418CtgCtgT88B.1.4270.000404
ORF1ab/nsp4418C418delTGC---77AY.40.000011
ORF1ab/nsp4418C418delTGC---77AY.4.50.000752
ORF1ab/nsp4418C418CtgCtgT77AY.99.20.000645
ORF1ab/nsp4418C418FtGctTc47B.1.10.000073
ORF1ab/nsp4418C418FtGCtTT37B.1.10.000054
ORF1ab/nsp4418C418delTGC---77B.1.1770.000092
ORF1ab/nsp4418C418del1tgCtg-26All0
ORF1ab/nsp4418C418del1tGct-c26All0
ORF1ab/nsp4418C418del1Tgc-gc16All0
ORF1ab/nsp4418C418del1tGCtA-16All0
ORF1ab/nsp4418C418RTgcCgc66B.1.1770.000079
ORF1ab/nsp4418C418delTGC---55AY.250.00003
ORF1ab/nsp4418C418CtgCtgT55AY.740.000578
ORF1ab/nsp4418C418FtGctTc55AY.98.10.000242
ORF1ab/nsp4418C418RTgcCgc55B.1.1600.000156
ORF1ab/nsp4418C418CtgCtgT55B.1.36.180.002101
ORF1ab/nsp4418C418CtgCtgT55D.20.000375
ORF1ab/nsp4418C418XtgCtgA34All0.000001
ORF1ab/nsp4418C418XtGCtAG14All0
ORF1ab/nsp4418C418CtgCtgT44AY.260.000113
ORF1ab/nsp4418C418CtgCtgT44AY.390.000099
ORF1ab/nsp4418C418delTGC---44AY.430.000018
ORF1ab/nsp4418C418CtgCtgT44B.1.1.2840.00043
ORF1ab/nsp4418C418CtgCtgT44B.1.1.5190.000159
ORF1ab/nsp4418C418CtgCtgT44B.1.36.240.024691
ORF1ab/nsp4418C418RTgcCgc44B.1.617.20.000015
ORF1ab/nsp4418C418GTgcGgc44P.10.000063
ORF1ab/nsp4418C418WtgCtgG33All0.000001
ORF1ab/nsp4418C418CtgCtgT33AY.1060.001005
ORF1ab/nsp4418C418CtgCtgT33AY.240.001293
ORF1ab/nsp4418C418CtgCtgT33AY.290.000047
ORF1ab/nsp4418C418RTgcCgc33AY.30.00003
ORF1ab/nsp4418C418CtgCtgT33AY.4.50.000322
ORF1ab/nsp4418C418CtgCtgT33AY.670.001393
ORF1ab/nsp4418C418CtgCtgT33AY.9.20.00011
ORF1ab/nsp4418C418CtgCtgT33B.1.1.3260.005282
ORF1ab/nsp4418C418CtgCtgT33B.1.2210.000213
ORF1ab/nsp4418C418CtgCtgT33B.1.36.290.001552
ORF1ab/nsp4418C418CtgCtgT33B.1.5260.000071
ORF1ab/nsp4418C418FtGctTc33B.1.617.20.000011
ORF1ab/nsp4418C418delTGC---33B.1.617.20.000011
ORF1ab/nsp4418C418FtGctTc33D.20.000225
ORF1ab/nsp4418C418WtgCtgG220.111111
ORF1ab/nsp4418C418YtGctAc120.055556
ORF1ab/nsp4418C418GTgcGgc120.055556
ORF1ab/nsp4418C418GTgCGgG120.055556
ORF1ab/nsp4418C418NTGcAAc120.055556
ORF1ab/nsp4418C418STgCAgT120.055556
ORF1ab/nsp4418C418YtGCtAT120.055556
ORF1ab/nsp4418C418STgcAgc120.055556
ORF1ab/nsp4418C418NTGCAAT120.055556
ORF1ab/nsp4418C418HTGcCAc22All0
ORF1ab/nsp4418C418NTGcAAc12All0
ORF1ab/nsp4418C418KTGCAAG12All0
ORF1ab/nsp4418C418KTGCAAA12All0
ORF1ab/nsp4418C418NTGCAAT12All0
ORF1ab/nsp4418C418CtgCtgT22AY.1000.000092
ORF1ab/nsp4418C418RTgcCgc22AY.1030.000012
ORF1ab/nsp4418C418CtgCtgT22AY.1200.000074
ORF1ab/nsp4418C418CtgCtgT22AY.200.000078
ORF1ab/nsp4418C418CtgCtgT22AY.230.000139
ORF1ab/nsp4418C418FtGctTc22AY.330.000134
ORF1ab/nsp4418C418CtgCtgT22AY.34.10.00102
ORF1ab/nsp4418C418RTgcCgc22AY.440.000012
ORF1ab/nsp4418C418CtgCtgT22AY.460.000208
ORF1ab/nsp4418C418CtgCtgT22AY.470.000062
ORF1ab/nsp4418C418FtGctTc22AY.50.000041
ORF1ab/nsp4418C418CtgCtgT22AY.600.001876
ORF1ab/nsp4418C418YtGctAc22B.10.000018
ORF1ab/nsp4418C418delTGC---22B.1.10.000036
ORF1ab/nsp4418C418CtgCtgT22B.1.1.2080.02439
ORF1ab/nsp4418C418CtgCtgT22B.1.1.2910.001485
ORF1ab/nsp4418C418CtgCtgT22B.1.1.3480.001592
ORF1ab/nsp4418C418CtgCtgT22B.1.1.3510.005587
ORF1ab/nsp4418C418CtgCtgT22B.1.1.3980.006452
ORF1ab/nsp4418C418CtgCtgT22B.1.1.4330.002849
ORF1ab/nsp4418C418RTgcCgc22B.1.1.70.000002
ORF1ab/nsp4418C418FtGctTc12B.1.2210.000071
ORF1ab/nsp4418C418FtGCtTT12B.1.2210.000071
ORF1ab/nsp4418C418CtgCtgT22B.1.2430.000139
ORF1ab/nsp4418C418GTgcGgc22B.1.2580.000133
ORF1ab/nsp4418C418CtgCtgT22B.1.4970.00063
ORF1ab/nsp4418C418CtgCtgT22B.1.5950.000522
ORF1ab/nsp4418C418CtgCtgT22B.400.000729
ORF1ab/nsp4418C418CtgCtgT22C.360.001821
ORF1ab/nsp4418C418RTgcCgc22K.20.08
ORF1ab/nsp4418C418delTGC---22P.1.10.000635
ORF1ab/nsp4418C418KTGCAAG110.055556
ORF1ab/nsp4418C418RTgCAgG110.055556
ORF1ab/nsp4418C418CtgCtgT110.055556
ORF1ab/nsp4418C418XtGCtAG110.055556
ORF1ab/nsp4418C418delTGC---11A0.000387
ORF1ab/nsp4418C418CtgCtgT11A.2.50.000499
ORF1ab/nsp4418C418STgcAgc11A.250.018182
ORF1ab/nsp4418C418del2TGc--c11All0
ORF1ab/nsp4418C418VTGcGTc11All0
ORF1ab/nsp4418C418LTGCCTT11All0
ORF1ab/nsp4418C418CtgCtgT11AM.40.003571
ORF1ab/nsp4418C418RTgcCgc11AY.1020.000027
ORF1ab/nsp4418C418delTGC---11AY.1080.001103
ORF1ab/nsp4418C418CtgCtgT11AY.1140.000231
ORF1ab/nsp4418C418CtgCtgT11AY.1160.000287
ORF1ab/nsp4418C418CtgCtgT11AY.1170.000085
ORF1ab/nsp4418C418FtGctTc11AY.1190.000035
ORF1ab/nsp4418C418CtgCtgT11AY.1210.000135
ORF1ab/nsp4418C418CtgCtgT11AY.160.00038
ORF1ab/nsp4418C418FtGctTc11AY.200.000039
ORF1ab/nsp4418C418delTGC---11AY.260.000028
ORF1ab/nsp4418C418KTGCAAA11AY.290.000016
ORF1ab/nsp4418C418RTgcCgc11AY.300.000396
ORF1ab/nsp4418C418RTgcCgc11AY.320.000532
ORF1ab/nsp4418C418CtgCtgT11AY.340.000097
ORF1ab/nsp4418C418CtgCtgT11AY.350.000233
ORF1ab/nsp4418C418CtgCtgT11AY.360.000148
ORF1ab/nsp4418C418FtGctTc11AY.360.000148
ORF1ab/nsp4418C418GTgcGgc11AY.40.000002
ORF1ab/nsp4418C418delTGC---11AY.4.30.000842
ORF1ab/nsp4418C418FtGctTc11AY.430.000004
ORF1ab/nsp4418C418del1tgCtg-11AY.430.000004
ORF1ab/nsp4418C418RTgcCgc11AY.430.000004
ORF1ab/nsp4418C418del1tgCtg-11AY.440.000006
ORF1ab/nsp4418C418FtGctTc11AY.440.000006
ORF1ab/nsp4418C418YtGctAc11AY.440.000006
ORF1ab/nsp4418C418CtgCtgT11AY.450.000122
ORF1ab/nsp4418C418CtgCtgT11AY.46.60.000072
ORF1ab/nsp4418C418CtgCtgT11AY.510.000909
ORF1ab/nsp4418C418delTGC---11AY.60.000041
ORF1ab/nsp4418C418CtgCtgT11AY.60.000041
ORF1ab/nsp4418C418CtgCtgT11AY.610.000105
ORF1ab/nsp4418C418delTGC---11AY.620.000436
ORF1ab/nsp4418C418RTgcCgc11AY.670.000464
ORF1ab/nsp4418C418delTGC---11AY.720.001361
ORF1ab/nsp4418C418CtgCtgT11AY.750.000056
ORF1ab/nsp4418C418delTGC---11AY.780.001541
ORF1ab/nsp4418C418CtgCtgT11AY.80.000606
ORF1ab/nsp4418C418YtGctAc11AY.840.000437
ORF1ab/nsp4418C418delTGC---11AY.90.000068
ORF1ab/nsp4418C418CtgCtgT11AY.9.10.000084
ORF1ab/nsp4418C418delTGC---11AY.9.20.000037
ORF1ab/nsp4418C418CtgCtgT11AY.980.000079
ORF1ab/nsp4418C418delTGC---11AY.990.001049
ORF1ab/nsp4418C418StGctCc11B0.000128
ORF1ab/nsp4418C418RTgcCgc11B0.000128
ORF1ab/nsp4418C418FtGctTc11B0.000128
ORF1ab/nsp4418C418del1tGct-c11B.10.000009
ORF1ab/nsp4418C418delTGC---11B.10.000009
ORF1ab/nsp4418C418XtgCtgA11B.10.000009
ORF1ab/nsp4418C418RTgcCgc11B.1.10.000018
ORF1ab/nsp4418C418HTGcCAc11B.1.1.1390.022727
ORF1ab/nsp4418C418CtgCtgT11B.1.1.2140.000055
ORF1ab/nsp4418C418GTgcGgc11B.1.1.2140.000055
ORF1ab/nsp4418C418WtgCtgG11B.1.1.250.000569
ORF1ab/nsp4418C418CtgCtgT11B.1.1.3050.003861
ORF1ab/nsp4418C418delTGC---11B.1.1.3120.001912
ORF1ab/nsp4418C418CtgCtgT11B.1.1.330.000421
ORF1ab/nsp4418C418CtgCtgT11B.1.1.3540.004386
ORF1ab/nsp4418C418StGctCc11B.1.1.3560.008547
ORF1ab/nsp4418C418FtGctTc11B.1.1.3760.005952
ORF1ab/nsp4418C418CtgCtgT11B.1.1.4200.001006
ORF1ab/nsp4418C418CtgCtgT11B.1.1.4410.05
ORF1ab/nsp4418C418GTgcGgc11B.1.1.70.000001
ORF1ab/nsp4418C418del1Tgc-gc11B.1.1.70.000001
ORF1ab/nsp4418C418LTGCCTT11B.1.1.70.000001
ORF1ab/nsp4418C418del2TGc--c11B.1.1.70.000001
ORF1ab/nsp4418C418STgcAgc11B.1.1600.000031
ORF1ab/nsp4418C418FtGctTc11B.1.1770.000013
ORF1ab/nsp4418C418delTGC---11B.1.177.110.001698
ORF1ab/nsp4418C418delTGC---11B.1.177.150.000631
ORF1ab/nsp4418C418delTGC---11B.1.177.160.000664
ORF1ab/nsp4418C418delTGC---11B.1.177.40.000211
ORF1ab/nsp4418C418delTGC---11B.1.177.540.000606
ORF1ab/nsp4418C418CtgCtgT11B.1.177.560.000668
ORF1ab/nsp4418C418delTGC---11B.1.177.760.002494
ORF1ab/nsp4418C418FtGctTc11B.1.177.770.000726
ORF1ab/nsp4418C418delTGC---11B.1.177.810.000189
ORF1ab/nsp4418C418delTGC---11B.1.20.000009
ORF1ab/nsp4418C418StGctCc11B.1.20.000009
ORF1ab/nsp4418C418YtGctAc11B.1.2340.000132
ORF1ab/nsp4418C418delTGC---11B.1.258.110.000396
ORF1ab/nsp4418C418CtgCtgT11B.1.258.170.000104
ORF1ab/nsp4418C418FtGctTc11B.1.258.170.000104
ORF1ab/nsp4418C418delTGC---11B.1.258.30.001675
ORF1ab/nsp4418C418RTgcCgc11B.1.3510.00003
ORF1ab/nsp4418C418CtgCtgT11B.1.351.30.000876
ORF1ab/nsp4418C418XtgCtgA11B.1.360.000146
ORF1ab/nsp4418C418StGctCc11B.1.36.10.00114
ORF1ab/nsp4418C418del1tGct-c11B.1.36.20.010753
ORF1ab/nsp4418C418CtgCtgT11B.1.4090.000781
ORF1ab/nsp4418C418CtgCtgT11B.1.4280.00102
ORF1ab/nsp4418C418YtGctAc11B.1.4290.000024
ORF1ab/nsp4418C418CtgCtgT11B.1.5050.004386
ORF1ab/nsp4418C418RTgcCgc11B.1.5250.000113
ORF1ab/nsp4418C418CtgCtgT11B.1.5700.002941
ORF1ab/nsp4418C418YtGctAc11B.1.5950.000261
ORF1ab/nsp4418C418CtgCtgT11B.1.6090.000479
ORF1ab/nsp4418C418CtgCtgT11B.1.617.10.000129
ORF1ab/nsp4418C418delTGC---11B.1.617.10.000129
ORF1ab/nsp4418C418HTGcCAc11B.1.617.20.000004
ORF1ab/nsp4418C418del1tGCtA-11B.1.617.20.000004
ORF1ab/nsp4418C418VTGcGTc11B.1.617.20.000004
ORF1ab/nsp4418C418XtgCtgA11B.1.617.20.000004
ORF1ab/nsp4418C418CtgCtgT11B.1.6210.000089
ORF1ab/nsp4418C418FtGctTc11B.1.6210.000089
ORF1ab/nsp4418C418StGctCc11B.1.6370.000073
ORF1ab/nsp4418C418delTGC---11C.350.000774
ORF1ab/nsp4418C418StGctCc11D.20.000075
ORF1ab/nsp4418C418delTGC---11P.10.000016
ORF1ab/nsp4418C418CtgCtgT11P.1.120.000484
ORF1ab/nsp4418C418CtgCtgT11P.1.140.000048
ORF1ab/nsp4418C418RTgcCgc11P.1.170.000162
ORF1ab/nsp4418C418CtgCtgT11P.1.70.000319
ORF1ab/nsp4418C418delTGC---11Q.10.000126
ORF1ab/nsp4418C418delTGC---11Q.20.000613
ORF1ab/nsp4418C418CtgCtgT11Q.80.000165
ORF1ab/nsp4418C418RTgcCgc11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.