CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : CodonNum = 35

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp4	35	K35R	K2798R	nonsyn	aAa	aGa	2560	2552	0.996875	8657-8659
ORF1ab/nsp4	35	K35R	K2798R	nonsyn	AAa	CGa	2560	8	0.003125	8657-8659
ORF1ab/nsp4	35	K35K	K2798K	syn	aaA	aaG	588	588	1	8657-8659
ORF1ab/nsp4	35	K35I	K2798I	nonsyn	aAa	aTa	348	181	0.520115	8657-8659
ORF1ab/nsp4	35	K35I	K2798I	nonsyn	aAA	aTT	348	162	0.465517	8657-8659
ORF1ab/nsp4	35	K35I	K2798I	nonsyn	aAA	aTC	348	5	0.0143678	8657-8659
ORF1ab/nsp4	35	K35N	K2798N	nonsyn	aaA	aaT	202	177	0.876238	8657-8659
ORF1ab/nsp4	35	K35N	K2798N	nonsyn	aaA	aaC	202	25	0.123762	8657-8659
ORF1ab/nsp4	35	K35X	K2798X	nonsyn	Aaa	Taa	156	156	1	8657-8659
ORF1ab/nsp4	35	K35Y	K2798Y	nonsyn	AaA	TaT	155	145	0.935484	8657-8659
ORF1ab/nsp4	35	K35Y	K2798Y	nonsyn	AaA	TaC	155	10	0.0645161	8657-8659
ORF1ab/nsp4	35	K35L	K2798L	nonsyn	AAa	TTa	151	148	0.980132	8657-8659
ORF1ab/nsp4	35	K35F	K2798F	nonsyn	AAA	TTT	151	146	0.966887	8657-8659
ORF1ab/nsp4	35	K35F	K2798F	nonsyn	AAA	TTC	151	5	0.0331126	8657-8659
ORF1ab/nsp4	35	K35L	K2798L	nonsyn	AAa	CTa	151	2	0.013245	8657-8659
ORF1ab/nsp4	35	K35L	K2798L	nonsyn	AAA	CTT	151	1	0.00662252	8657-8659
ORF1ab/nsp4	35	K35del	K2798del	del	AAA	---	111	111	1	8657-8659
ORF1ab/nsp4	35	K35Q	K2798Q	nonsyn	Aaa	Caa	53	53	1	8657-8659
ORF1ab/nsp4	35	K35E	K2798E	nonsyn	Aaa	Gaa	46	46	1	8657-8659
ORF1ab/nsp4	35	K35T	K2798T	nonsyn	aAa	aCa	14	14	1	8657-8659
ORF1ab/nsp4	35	K35del1	K2798del1	del	Aaa	-aa	10	9	0.9	8657-8659
ORF1ab/nsp4	35	K35del1	K2798del1	del	AaA	-aN	10	1	0.1	8657-8659
ORF1ab/nsp4	35	K35V	K2798V	nonsyn	AAa	GTa	6	3	0.5	8657-8659
ORF1ab/nsp4	35	K35V	K2798V	nonsyn	AAA	GTT	6	3	0.5	8657-8659
ORF1ab/nsp4	35	K35D	K2798D	nonsyn	AaA	GaT	3	3	1	8657-8659
ORF1ab/nsp4	35	K35del2	K2798del2	del	aAA	a--	2	1	0.5	8657-8659
ORF1ab/nsp4	35	K35G	K2798G	nonsyn	AAa	GGa	2	1	0.5	8657-8659
ORF1ab/nsp4	35	K35G	K2798G	nonsyn	AAA	GGG	2	1	0.5	8657-8659
ORF1ab/nsp4	35	K35del2	K2798del2	del	AAa	--a	2	1	0.5	8657-8659
ORF1ab/nsp4	35	K35H	K2798H	nonsyn	AaA	CaT	1	1	1	8657-8659

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp4	35	K35R	aAa	aGa	2552	2560	All	0.000488
ORF1ab/nsp4	35	K35R	AAa	CGa	8	2560	All	0.000002
ORF1ab/nsp4	35	K35K	aaA	aaG	588	588	All	0.000112
ORF1ab/nsp4	35	K35R	aAa	aGa	395	395	B.1.1.7	0.000354
ORF1ab/nsp4	35	K35I	aAa	aTa	181	348	All	0.000035
ORF1ab/nsp4	35	K35I	aAA	aTT	162	348	All	0.000031
ORF1ab/nsp4	35	K35I	aAA	aTC	5	348	All	0.000001
ORF1ab/nsp4	35	K35I	aAa	aTa	157	310	B.1.1.7	0.000141
ORF1ab/nsp4	35	K35I	aAA	aTT	148	310	B.1.1.7	0.000132
ORF1ab/nsp4	35	K35I	aAA	aTC	5	310	B.1.1.7	0.000004
ORF1ab/nsp4	35	K35K	aaA	aaG	269	269	B.1.1.217	0.978182
ORF1ab/nsp4	35	K35R	aAa	aGa	245	245	B.1	0.002244
ORF1ab/nsp4	35	K35R	aAa	aGa	215	215	AY.44	0.001309
ORF1ab/nsp4	35	K35N	aaA	aaT	177	202	All	0.000034
ORF1ab/nsp4	35	K35N	aaA	aaC	25	202	All	0.000005
ORF1ab/nsp4	35	K35N	aaA	aaT	153	164	B.1.1.7	0.000137
ORF1ab/nsp4	35	K35N	aaA	aaC	11	164	B.1.1.7	0.00001
ORF1ab/nsp4	35	K35X	Aaa	Taa	156	156	All	0.00003
ORF1ab/nsp4	35	K35Y	AaA	TaT	145	155	All	0.000028
ORF1ab/nsp4	35	K35Y	AaA	TaC	10	155	All	0.000002
ORF1ab/nsp4	35	K35L	AAa	TTa	148	151	All	0.000028
ORF1ab/nsp4	35	K35F	AAA	TTT	146	151	All	0.000028
ORF1ab/nsp4	35	K35F	AAA	TTC	5	151	All	0.000001
ORF1ab/nsp4	35	K35L	AAa	CTa	2	151	All	0
ORF1ab/nsp4	35	K35L	AAA	CTT	1	151	All	0
ORF1ab/nsp4	35	K35R	aAa	aGa	145	145	AY.103	0.0009
ORF1ab/nsp4	35	K35K	aaA	aaG	145	145	S.1	0.717822
ORF1ab/nsp4	35	K35Y	AaA	TaT	133	143	B.1.1.7	0.000119
ORF1ab/nsp4	35	K35Y	AaA	TaC	10	143	B.1.1.7	0.000009
ORF1ab/nsp4	35	K35X	Aaa	Taa	141	141	B.1.1.7	0.000126
ORF1ab/nsp4	35	K35F	AAA	TTT	134	139	B.1.1.7	0.00012
ORF1ab/nsp4	35	K35F	AAA	TTC	5	139	B.1.1.7	0.000004
ORF1ab/nsp4	35	K35L	AAa	TTa	136	138	B.1.1.7	0.000122
ORF1ab/nsp4	35	K35L	AAA	CTT	1	138	B.1.1.7	0.000001
ORF1ab/nsp4	35	K35L	AAa	CTa	1	138	B.1.1.7	0.000001
ORF1ab/nsp4	35	K35del	AAA	---	111	111	All	0.000021
ORF1ab/nsp4	35	K35R	aAa	aGa	105	106	B.1.617.2	0.000395
ORF1ab/nsp4	35	K35R	AAa	CGa	1	106	B.1.617.2	0.000004
ORF1ab/nsp4	35	K35R	aAa	aGa	88	88	B.1.1.519	0.003495
ORF1ab/nsp4	35	K35R	aAa	aGa	85	85	Q.3	0.012328
ORF1ab/nsp4	35	K35R	aAa	aGa	78	78	B.1.2	0.000687
ORF1ab/nsp4	35	K35R	aAa	aGa	62	62	AY.25	0.000373
ORF1ab/nsp4	35	K35Q	Aaa	Caa	53	53	All	0.00001
ORF1ab/nsp4	35	K35R	aAa	aGa	51	51	B.1.466.2	0.019953
ORF1ab/nsp4	35	K35R	aAa	aGa	49	49	B.1.429	0.001153
ORF1ab/nsp4	35	K35E	Aaa	Gaa	46	46	All	0.000009
ORF1ab/nsp4	35	K35del	AAA	---	46	46	B.1.1.7	0.000041
ORF1ab/nsp4	35	K35R	aAa	aGa	45	45	AY.3	0.000448
ORF1ab/nsp4	35	K35R	aAa	aGa	44	44	AY.117	0.003719
ORF1ab/nsp4	35	K35R	aAa	aGa	41	42	AY.23	0.00286
ORF1ab/nsp4	35	K35R	AAa	CGa	1	42	AY.23	0.00007
ORF1ab/nsp4	35	K35R	aAa	aGa	40	40	AY.69	0.007467
ORF1ab/nsp4	35	K35K	aaA	aaG	38	38	R.1	0.00342
ORF1ab/nsp4	35	K35R	aAa	aGa	33	34	AY.43	0.000146
ORF1ab/nsp4	35	K35R	AAa	CGa	1	34	AY.43	0.000004
ORF1ab/nsp4	35	K35R	aAa	aGa	34	34	B.1.1	0.000617
ORF1ab/nsp4	35	K35R	aAa	aGa	34	34	P.1	0.000536
ORF1ab/nsp4	35	K35R	aAa	aGa	33	33	B.1.139	0.024194
ORF1ab/nsp4	35	K35R	aAa	aGa	31	31	AY.26	0.000878
ORF1ab/nsp4	35	K35R	aAa	aGa	30	31	AY.4	0.000047
ORF1ab/nsp4	35	K35R	AAa	CGa	1	31	AY.4	0.000002
ORF1ab/nsp4	35	K35R	aAa	aGa	31	31	P.1.17	0.005015
ORF1ab/nsp4	35	K35R	aAa	aGa	30	30	B.1.351	0.000892
ORF1ab/nsp4	35	K35R	aAa	aGa	28	28	B.1.596	0.00244
ORF1ab/nsp4	35	K35R	aAa	aGa	25	25	B.1.526	0.000588
ORF1ab/nsp4	35	K35K	aaA	aaG	24	24	AY.3.1	0.002046
ORF1ab/nsp4	35	K35R	aAa	aGa	24	24	B.1.619.1	0.015394
ORF1ab/nsp4	35	K35R	aAa	aGa	23	23	AY.20	0.000894
ORF1ab/nsp4	35	K35R	aAa	aGa	21	21	B.1.497	0.00661
ORF1ab/nsp4	35	K35K	aaA	aaG	19	19	B.1.466.2	0.007433
ORF1ab/nsp4	35	K35R	aAa	aGa	17	17	B.1.177	0.000224
ORF1ab/nsp4	35	K35R	aAa	aGa	16	16	AY.100	0.000736
ORF1ab/nsp4	35	K35K	aaA	aaG	15	15	AY.29	0.000237
ORF1ab/nsp4	35	K35T	aAa	aCa	14	14	All	0.000003
ORF1ab/nsp4	35	K35R	aAa	aGa	14	14	AY.119	0.000494
ORF1ab/nsp4	35	K35R	aAa	aGa	14	14	AY.120.1	0.004494
ORF1ab/nsp4	35	K35R	aAa	aGa	14	14	AY.47	0.000435
ORF1ab/nsp4	35	K35K	aaA	aaG	14	14	P.1	0.000221
ORF1ab/nsp4	35	K35R	aAa	aGa	13	13	AY.39	0.000321
ORF1ab/nsp4	35	K35Q	Aaa	Caa	13	13	B.1.2	0.000114
ORF1ab/nsp4	35	K35R	aAa	aGa	13	13	B.1.396	0.009174
ORF1ab/nsp4	35	K35I	aAA	aTT	6	12	P.1	0.000095
ORF1ab/nsp4	35	K35I	aAa	aTa	6	12	P.1	0.000095
ORF1ab/nsp4	35	K35R	aAa	aGa	9	11	AY.46	0.000937
ORF1ab/nsp4	35	K35R	AAa	CGa	2	11	AY.46	0.000208
ORF1ab/nsp4	35	K35R	aAa	aGa	11	11	AY.54	0.001049
ORF1ab/nsp4	35	K35del1	Aaa	-aa	9	10	All	0.000002
ORF1ab/nsp4	35	K35del1	AaA	-aN	1	10	All	0
ORF1ab/nsp4	35	K35N	aaA	aaC	9	10	AY.25	0.000054
ORF1ab/nsp4	35	K35N	aaA	aaT	1	10	AY.25	0.000006
ORF1ab/nsp4	35	K35R	aAa	aGa	10	10	B.1.234	0.001319
ORF1ab/nsp4	35	K35R	aAa	aGa	9	9	AY.24	0.003879
ORF1ab/nsp4	35	K35del	AAA	---	9	9	B.1	0.000082
ORF1ab/nsp4	35	K35K	aaA	aaG	9	9	B.1.1.309	0.052632
ORF1ab/nsp4	35	K35R	aAa	aGa	9	9	B.1.1.318	0.002716
ORF1ab/nsp4	35	K35K	aaA	aaG	8	8	B.1.1.7	0.000007
ORF1ab/nsp4	35	K35R	aAa	aGa	8	8	C.36	0.007286
ORF1ab/nsp4	35	K35R	aAa	aGa	7	7	AY.42	0.000282
ORF1ab/nsp4	35	K35R	aAa	aGa	7	7	B.1.243	0.000487
ORF1ab/nsp4	35	K35V	AAa	GTa	3	6	All	0.000001
ORF1ab/nsp4	35	K35V	AAA	GTT	3	6	All	0.000001
ORF1ab/nsp4	35	K35R	aAa	aGa	6	6	AY.113	0.000854
ORF1ab/nsp4	35	K35R	aAa	aGa	6	6	AY.118	0.000376
ORF1ab/nsp4	35	K35K	aaA	aaG	6	6	AY.4	0.000009
ORF1ab/nsp4	35	K35R	aAa	aGa	6	6	AY.5	0.000124
ORF1ab/nsp4	35	K35K	aaA	aaG	6	6	B.1	0.000055
ORF1ab/nsp4	35	K35Q	Aaa	Caa	6	6	B.1	0.000055
ORF1ab/nsp4	35	K35V	AAA	GTT	3	6	B.1.1.7	0.000003
ORF1ab/nsp4	35	K35V	AAa	GTa	3	6	B.1.1.7	0.000003
ORF1ab/nsp4	35	K35R	aAa	aGa	6	6	B.1.177.81	0.001136
ORF1ab/nsp4	35	K35E	Aaa	Gaa	6	6	B.1.36	0.000875
ORF1ab/nsp4	35	K35R	aAa	aGa	6	6	B.1.576	0.00544
ORF1ab/nsp4	35	K35R	aAa	aGa	6	6	B.1.582	0.002944
ORF1ab/nsp4	35	K35R	aAa	aGa	6	6	B.1.595	0.001566
ORF1ab/nsp4	35	K35R	aAa	aGa	6	6	B.1.609	0.002876
ORF1ab/nsp4	35	K35R	aAa	aGa	6	6	B.1.621	0.000531
ORF1ab/nsp4	35	K35Y	AaA	TaT	6	6	P.1	0.000095
ORF1ab/nsp4	35	K35L	AAa	TTa	6	6	P.1	0.000095
ORF1ab/nsp4	35	K35F	AAA	TTT	6	6	P.1	0.000095
ORF1ab/nsp4	35	K35N	aaA	aaT	6	6	P.1	0.000095
ORF1ab/nsp4	35	K35X	Aaa	Taa	6	6	P.1	0.000095
ORF1ab/nsp4	35	K35R	aAa	aGa	6	6	P.1.16	0.002245
ORF1ab/nsp4	35	K35K	aaA	aaG	5	5	AY.103	0.000031
ORF1ab/nsp4	35	K35R	aAa	aGa	5	5	AY.67	0.002321
ORF1ab/nsp4	35	K35I	aAa	aTa	3	5	B.1	0.000027
ORF1ab/nsp4	35	K35I	aAA	aTT	2	5	B.1	0.000018
ORF1ab/nsp4	35	K35R	aAa	aGa	5	5	B.1.1.222	0.00102
ORF1ab/nsp4	35	K35del	AAA	---	5	5	B.1.177	0.000066
ORF1ab/nsp4	35	K35Q	Aaa	Caa	5	5	B.1.596	0.000436
ORF1ab/nsp4	35	K35R	aAa	aGa	5	5	B.1.637	0.000365
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	A	0.001548
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	AY.13	0.000644
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	AY.3.1	0.000341
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	AY.33	0.000267
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	AY.35	0.000932
ORF1ab/nsp4	35	K35del	AAA	---	4	4	AY.4	0.000006
ORF1ab/nsp4	35	K35E	Aaa	Gaa	4	4	AY.4	0.000006
ORF1ab/nsp4	35	K35Q	Aaa	Caa	4	4	AY.43	0.000018
ORF1ab/nsp4	35	K35Q	Aaa	Caa	4	4	AY.46	0.000416
ORF1ab/nsp4	35	K35K	aaA	aaG	4	4	AY.5	0.000083
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	AY.75	0.000224
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	AY.84	0.00175
ORF1ab/nsp4	35	K35I	aAa	aTa	2	4	B.1.1	0.000036
ORF1ab/nsp4	35	K35I	aAA	aTT	2	4	B.1.1	0.000036
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	B.1.1.220	0.007435
ORF1ab/nsp4	35	K35E	Aaa	Gaa	4	4	B.1.1.7	0.000004
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	B.1.369	0.001141
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	B.1.427	0.000202
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	B.1.564	0.001704
ORF1ab/nsp4	35	K35K	aaA	aaG	4	4	B.1.617.2	0.000015
ORF1ab/nsp4	35	K35I	aAa	aTa	3	4	B.1.617.2	0.000011
ORF1ab/nsp4	35	K35I	aAA	aTT	1	4	B.1.617.2	0.000004
ORF1ab/nsp4	35	K35del	AAA	---	4	4	B.1.621	0.000354
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	P.1.10	0.001078
ORF1ab/nsp4	35	K35R	aAa	aGa	4	4	P.1.12	0.001936
ORF1ab/nsp4	35	K35K	aaA	aaG	3	3	A.2.5.2	0.004717
ORF1ab/nsp4	35	K35D	AaA	GaT	3	3	All	0.000001
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	AY.1	0.001187
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	AY.110	0.000338
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	AY.14	0.000264
ORF1ab/nsp4	35	K35N	aaA	aaT	2	3	AY.23	0.000139
ORF1ab/nsp4	35	K35N	aaA	aaC	1	3	AY.23	0.00007
ORF1ab/nsp4	35	K35T	aAa	aCa	3	3	AY.4	0.000005
ORF1ab/nsp4	35	K35del	AAA	---	3	3	AY.4.5	0.000322
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	AY.5.3	0.001012
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	AY.51	0.002727
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	AY.98.1	0.000145
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	AY.99.2	0.000276
ORF1ab/nsp4	35	K35N	aaA	aaT	3	3	B.1.1	0.000054
ORF1ab/nsp4	35	K35D	AaA	GaT	3	3	B.1.1.7	0.000003
ORF1ab/nsp4	35	K35T	aAa	aCa	3	3	B.1.1.7	0.000003
ORF1ab/nsp4	35	K35K	aaA	aaG	3	3	B.1.160	0.000094
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	B.1.177.73	0.001699
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	B.1.189	0.012876
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	B.1.239	0.003663
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	B.1.416.1	0.004687
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	B.1.470	0.004213
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	B.1.525	0.000339
ORF1ab/nsp4	35	K35E	Aaa	Gaa	3	3	B.1.617.2	0.000011
ORF1ab/nsp4	35	K35del	AAA	---	3	3	B.1.617.2	0.000011
ORF1ab/nsp4	35	K35Q	Aaa	Caa	3	3	B.1.617.2	0.000011
ORF1ab/nsp4	35	K35R	aAa	aGa	3	3	C.37	0.000348
ORF1ab/nsp4	35	K35X	Aaa	Taa	2	2		0.111111
ORF1ab/nsp4	35	K35del	AAA	---	2	2		0.111111
ORF1ab/nsp4	35	K35N	aaA	aaT	2	2		0.111111
ORF1ab/nsp4	35	K35E	Aaa	Gaa	2	2		0.111111
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	A.2.5	0.000998
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	A.23.1	0.001408
ORF1ab/nsp4	35	K35del2	aAA	a--	1	2	All	0
ORF1ab/nsp4	35	K35G	AAA	GGG	1	2	All	0
ORF1ab/nsp4	35	K35G	AAa	GGa	1	2	All	0
ORF1ab/nsp4	35	K35del2	AAa	--a	1	2	All	0
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	AU.2	0.004843
ORF1ab/nsp4	35	K35E	Aaa	Gaa	2	2	AY.100	0.000092
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	AY.102	0.000053
ORF1ab/nsp4	35	K35I	aAA	aTT	1	2	AY.110	0.000113
ORF1ab/nsp4	35	K35I	aAa	aTa	1	2	AY.110	0.000113
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	AY.116.1	0.000623
ORF1ab/nsp4	35	K35I	aAa	aTa	1	2	AY.25	0.000006
ORF1ab/nsp4	35	K35I	aAA	aTT	1	2	AY.25	0.000006
ORF1ab/nsp4	35	K35K	aaA	aaG	2	2	AY.26	0.000057
ORF1ab/nsp4	35	K35Q	Aaa	Caa	2	2	AY.4	0.000003
ORF1ab/nsp4	35	K35I	aAa	aTa	2	2	AY.4	0.000003
ORF1ab/nsp4	35	K35N	aaA	aaC	2	2	AY.4	0.000003
ORF1ab/nsp4	35	K35del	AAA	---	2	2	AY.43	0.000009
ORF1ab/nsp4	35	K35E	Aaa	Gaa	2	2	AY.43	0.000009
ORF1ab/nsp4	35	K35K	aaA	aaG	2	2	AY.43	0.000009
ORF1ab/nsp4	35	K35T	aAa	aCa	2	2	AY.43	0.000009
ORF1ab/nsp4	35	K35Q	Aaa	Caa	2	2	AY.46.6	0.000144
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	AY.48	0.00093
ORF1ab/nsp4	35	K35E	Aaa	Gaa	2	2	AY.52	0.001629
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	AY.61	0.00021
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	AY.68	0.000547
ORF1ab/nsp4	35	K35R	aAa	aGa	1	2	AY.7.1	0.000113
ORF1ab/nsp4	35	K35R	AAa	CGa	1	2	AY.7.1	0.000113
ORF1ab/nsp4	35	K35R	AAa	CGa	1	2	AY.9	0.000068
ORF1ab/nsp4	35	K35R	aAa	aGa	1	2	AY.9	0.000068
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	AY.9.1	0.000167
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	AY.9.2	0.000073
ORF1ab/nsp4	35	K35N	aaA	aaT	2	2	B.1	0.000018
ORF1ab/nsp4	35	K35E	Aaa	Gaa	2	2	B.1	0.000018
ORF1ab/nsp4	35	K35L	AAa	TTa	1	2	B.1	0.000009
ORF1ab/nsp4	35	K35L	AAa	CTa	1	2	B.1	0.000009
ORF1ab/nsp4	35	K35del	AAA	---	2	2	B.1.1	0.000036
ORF1ab/nsp4	35	K35F	AAA	TTT	2	2	B.1.1	0.000036
ORF1ab/nsp4	35	K35X	Aaa	Taa	2	2	B.1.1	0.000036
ORF1ab/nsp4	35	K35Y	AaA	TaT	2	2	B.1.1	0.000036
ORF1ab/nsp4	35	K35K	aaA	aaG	2	2	B.1.1	0.000036
ORF1ab/nsp4	35	K35L	AAa	TTa	2	2	B.1.1	0.000036
ORF1ab/nsp4	35	K35del	AAA	---	2	2	B.1.1.315	0.016949
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.1.335	0.025974
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.1.375	0.02381
ORF1ab/nsp4	35	K35del2	AAa	--a	1	2	B.1.1.7	0.000001
ORF1ab/nsp4	35	K35del2	aAA	a--	1	2	B.1.1.7	0.000001
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.160	0.000062
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.195	0.01005
ORF1ab/nsp4	35	K35E	Aaa	Gaa	2	2	B.1.2	0.000018
ORF1ab/nsp4	35	K35del	AAA	---	2	2	B.1.2	0.000018
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.240	0.000431
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.258	0.000133
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.349	0.00143
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.404	0.002604
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.416	0.002538
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.546	0.007407
ORF1ab/nsp4	35	K35I	aAa	aTa	1	2	B.1.576	0.000907
ORF1ab/nsp4	35	K35I	aAA	aTT	1	2	B.1.576	0.000907
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.606	0.012048
ORF1ab/nsp4	35	K35K	aaA	aaG	2	2	B.1.617.1	0.000258
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.617.1	0.000258
ORF1ab/nsp4	35	K35del1	Aaa	-aa	2	2	B.1.617.2	0.000008
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.619	0.001742
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.620	0.001892
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.623	0.001073
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	B.1.628	0.000705
ORF1ab/nsp4	35	K35E	Aaa	Gaa	2	2	C.37	0.000232
ORF1ab/nsp4	35	K35R	aAa	aGa	2	2	P.1.13	0.001797
ORF1ab/nsp4	35	K35del	AAA	---	1	1	A.2.4	0.003367
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	A.23	0.010526
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	A.27	0.001656
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AA.1	0.007246
ORF1ab/nsp4	35	K35H	AaA	CaT	1	1	All	0
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	AY.102	0.000027
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	AY.103	0.000006
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	AY.103	0.000006
ORF1ab/nsp4	35	K35I	aAa	aTa	1	1	AY.103	0.000006
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.107	0.000466
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.108	0.001103
ORF1ab/nsp4	35	K35K	aaA	aaG	1	1	AY.109	0.00074
ORF1ab/nsp4	35	K35N	aaA	aaT	1	1	AY.110	0.000113
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.111	0.000183
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.114	0.000231
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.120	0.000037
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.16.1	0.00047
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	AY.23	0.00007
ORF1ab/nsp4	35	K35K	aaA	aaG	1	1	AY.25	0.000006
ORF1ab/nsp4	35	K35X	Aaa	Taa	1	1	AY.25	0.000006
ORF1ab/nsp4	35	K35F	AAA	TTT	1	1	AY.25	0.000006
ORF1ab/nsp4	35	K35del	AAA	---	1	1	AY.25	0.000006
ORF1ab/nsp4	35	K35L	AAa	TTa	1	1	AY.25	0.000006
ORF1ab/nsp4	35	K35Y	AaA	TaT	1	1	AY.25	0.000006
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	AY.3	0.00001
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.30	0.000396
ORF1ab/nsp4	35	K35T	aAa	aCa	1	1	AY.33	0.000067
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.34	0.000097
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	AY.34	0.000097
ORF1ab/nsp4	35	K35del	AAA	---	1	1	AY.34.1	0.00051
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.38	0.000499
ORF1ab/nsp4	35	K35T	aAa	aCa	1	1	AY.39.1	0.00004
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.4.2	0.000022
ORF1ab/nsp4	35	K35del	AAA	---	1	1	AY.42	0.00004
ORF1ab/nsp4	35	K35N	aaA	aaC	1	1	AY.42	0.00004
ORF1ab/nsp4	35	K35N	aaA	aaC	1	1	AY.43	0.000004
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.45	0.000122
ORF1ab/nsp4	35	K35G	AAa	GGa	1	1	AY.46	0.000104
ORF1ab/nsp4	35	K35del	AAA	---	1	1	AY.46	0.000104
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	AY.46	0.000104
ORF1ab/nsp4	35	K35del	AAA	---	1	1	AY.46.2	0.000635
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.46.4	0.000165
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.46.6	0.000072
ORF1ab/nsp4	35	K35K	aaA	aaG	1	1	AY.47	0.000031
ORF1ab/nsp4	35	K35del1	Aaa	-aa	1	1	AY.54	0.000095
ORF1ab/nsp4	35	K35K	aaA	aaG	1	1	AY.6	0.000041
ORF1ab/nsp4	35	K35del	AAA	---	1	1	AY.60	0.000938
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.62	0.000436
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	AY.7.1	0.000113
ORF1ab/nsp4	35	K35X	Aaa	Taa	1	1	AY.7.2	0.000559
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.71	0.000475
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.73	0.000665
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	AY.75	0.000056
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.83	0.001724
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	AY.84	0.000437
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	AY.9	0.000068
ORF1ab/nsp4	35	K35del	AAA	---	1	1	AY.9	0.000068
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.92	0.000287
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.94	0.000443
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AY.98	0.000079
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	AZ.5	0.003509
ORF1ab/nsp4	35	K35del1	Aaa	-aa	1	1	B	0.000128
ORF1ab/nsp4	35	K35X	Aaa	Taa	1	1	B.1	0.000009
ORF1ab/nsp4	35	K35T	aAa	aCa	1	1	B.1	0.000009
ORF1ab/nsp4	35	K35G	AAA	GGG	1	1	B.1	0.000009
ORF1ab/nsp4	35	K35Y	AaA	TaT	1	1	B.1	0.000009
ORF1ab/nsp4	35	K35F	AAA	TTT	1	1	B.1	0.000009
ORF1ab/nsp4	35	K35del1	Aaa	-aa	1	1	B.1	0.000009
ORF1ab/nsp4	35	K35del1	AaA	-aN	1	1	B.1.1	0.000018
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	B.1.1	0.000018
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.1	0.000327
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.189	0.001513
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.210	0.005714
ORF1ab/nsp4	35	K35K	aaA	aaG	1	1	B.1.1.222	0.000204
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.28	0.000311
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.291	0.000742
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.1.306	0.000438
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.1.311	0.000358
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.322	0.008772
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.362	0.005618
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.372	0.000689
ORF1ab/nsp4	35	K35I	aAa	aTa	1	1	B.1.1.39	0.00051
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.397	0.002252
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	B.1.1.409	0.002833
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.1.409	0.002833
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.440	0.011765
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.448	0.002033
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.5	0.008333
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.507	0.008696
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.518	0.006329
ORF1ab/nsp4	35	K35N	aaA	aaT	1	1	B.1.1.519	0.00004
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.1.519	0.00004
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.1.523	0.001563
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	B.1.1.7	0.000001
ORF1ab/nsp4	35	K35H	AaA	CaT	1	1	B.1.1.7	0.000001
ORF1ab/nsp4	35	K35del1	Aaa	-aa	1	1	B.1.1.7	0.000001
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.1.70	0.000341
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.140	0.018868
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.160	0.000031
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.160.31	0.008065
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.170	0.00431
ORF1ab/nsp4	35	K35del1	Aaa	-aa	1	1	B.1.177	0.000013
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.177.11	0.001698
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.177.11	0.001698
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.177.17	0.000821
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.177.21	0.000076
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	B.1.177.21	0.000076
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.177.23	0.003236
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.177.44	0.000519
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.177.54	0.000606
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.177.57	0.000281
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.177.62	0.001192
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.177.63	0.002703
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.177.7	0.000165
ORF1ab/nsp4	35	K35N	aaA	aaT	1	1	B.1.177.7	0.000165
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.177.83	0.001481
ORF1ab/nsp4	35	K35N	aaA	aaT	1	1	B.1.2	0.000009
ORF1ab/nsp4	35	K35K	aaA	aaG	1	1	B.1.2	0.000009
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.206	0.000816
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.221	0.000071
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.232	0.000537
ORF1ab/nsp4	35	K35I	aAa	aTa	1	1	B.1.234	0.000132
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.234	0.000132
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	B.1.243	0.00007
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	B.1.243	0.00007
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.258.11	0.000396
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	B.1.264	0.012346
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.284	0.013158
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.305	0.002151
ORF1ab/nsp4	35	K35K	aaA	aaG	1	1	B.1.311	0.000275
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.350	0.002933
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	B.1.351	0.00003
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.351.2	0.000303
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.356	0.001727
ORF1ab/nsp4	35	K35del1	Aaa	-aa	1	1	B.1.36	0.000146
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.36	0.000146
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.36.18	0.00042
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.36.29	0.000517
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.36.35	0.002604
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.367	0.000792
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	B.1.396	0.000706
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	B.1.400	0.000429
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.400	0.000429
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.441	0.009615
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.459	0.004082
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	B.1.462	0.007246
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.462	0.007246
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.466.1	0.007194
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.469	0.00361
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.474	0.001901
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.501	0.007353
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.524	0.001406
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	B.1.525	0.000113
ORF1ab/nsp4	35	K35K	aaA	aaG	1	1	B.1.525	0.000113
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.544	0.006024
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.558	0.004566
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.565	0.00081
ORF1ab/nsp4	35	K35N	aaA	aaT	1	1	B.1.574	0.002151
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.574	0.002151
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.575	0.000303
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.575.1	0.002439
ORF1ab/nsp4	35	K35F	AAA	TTT	1	1	B.1.576	0.000907
ORF1ab/nsp4	35	K35L	AAa	TTa	1	1	B.1.576	0.000907
ORF1ab/nsp4	35	K35X	Aaa	Taa	1	1	B.1.576	0.000907
ORF1ab/nsp4	35	K35Y	AaA	TaT	1	1	B.1.576	0.000907
ORF1ab/nsp4	35	K35N	aaA	aaT	1	1	B.1.576	0.000907
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.577	0.000687
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.580	0.004065
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.581	0.009434
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	B.1.590	0.004545
ORF1ab/nsp4	35	K35I	aAa	aTa	1	1	B.1.595	0.000261
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	B.1.595	0.000261
ORF1ab/nsp4	35	K35del	AAA	---	1	1	B.1.596	0.000087
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.612	0.002653
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.616	0.02439
ORF1ab/nsp4	35	K35T	aAa	aCa	1	1	B.1.617.2	0.000004
ORF1ab/nsp4	35	K35Y	AaA	TaT	1	1	B.1.617.2	0.000004
ORF1ab/nsp4	35	K35X	Aaa	Taa	1	1	B.1.617.2	0.000004
ORF1ab/nsp4	35	K35L	AAa	TTa	1	1	B.1.617.2	0.000004
ORF1ab/nsp4	35	K35F	AAA	TTT	1	1	B.1.617.2	0.000004
ORF1ab/nsp4	35	K35N	aaA	aaT	1	1	B.1.617.2	0.000004
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.621.1	0.000506
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	B.1.625	0.002353
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.627	0.00202
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.78	0.008547
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.1.9	0.006173
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.3	0.000831
ORF1ab/nsp4	35	K35del1	Aaa	-aa	1	1	B.34	0.013699
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	B.4	0.002208
ORF1ab/nsp4	35	K35T	aAa	aCa	1	1	B.40	0.000364
ORF1ab/nsp4	35	K35E	Aaa	Gaa	1	1	B.55	0.00295
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	C.1	0.002392
ORF1ab/nsp4	35	K35T	aAa	aCa	1	1	C.35	0.000774
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	C.35	0.000774
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	C.36.1	0.004149
ORF1ab/nsp4	35	K35del	AAA	---	1	1	C.37	0.000116
ORF1ab/nsp4	35	K35N	aaA	aaT	1	1	D.2	0.000075
ORF1ab/nsp4	35	K35Q	Aaa	Caa	1	1	D.2	0.000075
ORF1ab/nsp4	35	K35I	aAa	aTa	1	1	D.2	0.000075
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	P.1.10.1	0.00813
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	P.2	0.000187
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	Q.1	0.000126
ORF1ab/nsp4	35	K35R	aAa	aGa	1	1	Q.4	0.000455
ORF1ab/nsp4	35	K35del	AAA	---	1	1	U.3	0.003861

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.