CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : CodonNum = 27

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp427I27TI2790TnonsynaTaaCa1986198618633-8635
ORF1ab/nsp427I27LI2790LnonsynAtaCta2422310.9545458633-8635
ORF1ab/nsp427I27LI2790LnonsynAtaTta24290.03719018633-8635
ORF1ab/nsp427I27LI2790LnonsynAtACtT24220.008264468633-8635
ORF1ab/nsp427I27VI2790VnonsynAtaGta14414418633-8635
ORF1ab/nsp427I27delI2790deldelATA---737318633-8635
ORF1ab/nsp427I27MI2790MnonsynatAatG595918633-8635
ORF1ab/nsp427I27II2790IsynatAatT15110.7333338633-8635
ORF1ab/nsp427I27II2790IsynatAatC1540.2666678633-8635
ORF1ab/nsp427I27del1I2790del1delatAat-12100.8333338633-8635
ORF1ab/nsp427I27del1I2790del1delAtACt-1210.08333338633-8635
ORF1ab/nsp427I27del1I2790del1delaTaa-a1210.08333338633-8635
ORF1ab/nsp427I27RI2790RnonsynaTaaGa840.58633-8635
ORF1ab/nsp427I27RI2790RnonsynATaCGa820.258633-8635
ORF1ab/nsp427I27RI2790RnonsynATACGT820.258633-8635
ORF1ab/nsp427I27KI2790KnonsynaTaaAa2218633-8635
ORF1ab/nsp427I27SI2790SnonsynaTAaGT2218633-8635
ORF1ab/nsp427I27del2I2790del2delaTAa--2218633-8635
ORF1ab/nsp427I27FI2790FnonsynAtATtT1118633-8635

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp427I27TaTaaCa19861986All0.00038
ORF1ab/nsp427I27TaTaaCa996996AY.600.934334
ORF1ab/nsp427I27TaTaaCa285285B.1.6340.976027
ORF1ab/nsp427I27LAtaCta231242All0.000044
ORF1ab/nsp427I27LAtaTta9242All0.000002
ORF1ab/nsp427I27LAtACtT2242All0
ORF1ab/nsp427I27LAtaCta196196AY.40.000305
ORF1ab/nsp427I27VAtaGta144144All0.000028
ORF1ab/nsp427I27TaTaaCa124124AY.40.000193
ORF1ab/nsp427I27TaTaaCa7676B.1.1.70.000068
ORF1ab/nsp427I27delATA---7373All0.000014
ORF1ab/nsp427I27TaTaaCa6464B.1.2410.051948
ORF1ab/nsp427I27MatAatG5959All0.000011
ORF1ab/nsp427I27TaTaaCa5151B.1.2430.003549
ORF1ab/nsp427I27TaTaaCa4545AY.250.000271
ORF1ab/nsp427I27TaTaaCa3838AY.1200.001413
ORF1ab/nsp427I27delATA---3131B.1.1.70.000028
ORF1ab/nsp427I27TaTaaCa2929AY.30.000288
ORF1ab/nsp427I27VAtaGta2323B.1.1.70.000021
ORF1ab/nsp427I27TaTaaCa2323B.1.177.730.013024
ORF1ab/nsp427I27VAtaGta2222AY.40.000034
ORF1ab/nsp427I27MatAatG2222B.1.20.000194
ORF1ab/nsp427I27VAtaGta1919AY.250.000114
ORF1ab/nsp427I27VAtaGta1919AY.750.001064
ORF1ab/nsp427I27TaTaaCa1818B.1.6230.009657
ORF1ab/nsp427I27TaTaaCa1717B.1.6370.001242
ORF1ab/nsp427I27IatAatT1115All0.000002
ORF1ab/nsp427I27IatAatC415All0.000001
ORF1ab/nsp427I27VAtaGta1414B.6.60.012444
ORF1ab/nsp427I27TaTaaCa1313B.1.2580.000865
ORF1ab/nsp427I27del1atAat-1012All0.000002
ORF1ab/nsp427I27del1AtACt-112All0
ORF1ab/nsp427I27del1aTaa-a112All0
ORF1ab/nsp427I27TaTaaCa1212B.1.258.110.004756
ORF1ab/nsp427I27TaTaaCa1111B.10.000101
ORF1ab/nsp427I27TaTaaCa1111B.1.4000.004719
ORF1ab/nsp427I27TaTaaCa1111B.1.617.20.000041
ORF1ab/nsp427I27TaTaaCa1010B.1.6210.000885
ORF1ab/nsp427I27LAtaCta99B.1.5260.000212
ORF1ab/nsp427I27RaTaaGa48All0.000001
ORF1ab/nsp427I27RATaCGa28All0
ORF1ab/nsp427I27RATACGT28All0
ORF1ab/nsp427I27TaTaaCa88AY.420.000322
ORF1ab/nsp427I27VAtaGta88B.10.000073
ORF1ab/nsp427I27TaTaaCa88B.1.1770.000105
ORF1ab/nsp427I27TaTaaCa77AY.330.000467
ORF1ab/nsp427I27MatAatG77AY.40.000011
ORF1ab/nsp427I27TaTaaCa77AY.470.000218
ORF1ab/nsp427I27TaTaaCa77B.1.20.000062
ORF1ab/nsp427I27RaTaaGa260.111111
ORF1ab/nsp427I27RATaCGa260.111111
ORF1ab/nsp427I27RATACGT260.111111
ORF1ab/nsp427I27VAtaGta66AY.1030.000037
ORF1ab/nsp427I27TaTaaCa66AY.440.000037
ORF1ab/nsp427I27LAtaCta66B.1.617.20.000023
ORF1ab/nsp427I27IatAatT350.166667
ORF1ab/nsp427I27IatAatC250.111111
ORF1ab/nsp427I27LAtACtT250.111111
ORF1ab/nsp427I27LAtaCta250.111111
ORF1ab/nsp427I27LAtaTta150.055556
ORF1ab/nsp427I27VAtaGta55AY.30.00005
ORF1ab/nsp427I27delATA---55AY.40.000008
ORF1ab/nsp427I27delATA---55AY.4.50.000537
ORF1ab/nsp427I27TaTaaCa55AY.450.000608
ORF1ab/nsp427I27VAtaGta55AY.850.002136
ORF1ab/nsp427I27IatAatT55B.1.1.470.026738
ORF1ab/nsp427I27TaTaaCa55B.1.1.5060.185185
ORF1ab/nsp427I27TaTaaCa55B.1.4270.000252
ORF1ab/nsp427I27TaTaaCa55B.1.5250.000566
ORF1ab/nsp427I27MatAatG55B.1.617.20.000019
ORF1ab/nsp427I27TaTaaCa55P.10.000079
ORF1ab/nsp427I27MatAatG44AY.590.002119
ORF1ab/nsp427I27delATA---44B.10.000037
ORF1ab/nsp427I27del1atAat-44B.1.1.70.000004
ORF1ab/nsp427I27LAtaCta34B.1.1.70.000003
ORF1ab/nsp427I27LAtaTta14B.1.1.70.000001
ORF1ab/nsp427I27TaTaaCa44B.1.466.10.028777
ORF1ab/nsp427I27TaTaaCa44R.10.00036
ORF1ab/nsp427I27MatAatG33AY.1020.00008
ORF1ab/nsp427I27TaTaaCa33AY.1030.000019
ORF1ab/nsp427I27MatAatG33AY.1030.000019
ORF1ab/nsp427I27TaTaaCa33AY.200.000117
ORF1ab/nsp427I27TaTaaCa33AY.430.000013
ORF1ab/nsp427I27TaTaaCa33AY.650.001599
ORF1ab/nsp427I27delATA---33B.1.1770.00004
ORF1ab/nsp427I27TaTaaCa33B.1.177.870.002183
ORF1ab/nsp427I27VAtaGta33B.1.4290.000071
ORF1ab/nsp427I27TaTaaCa33B.1.5260.000071
ORF1ab/nsp427I27SaTAaGT220.111111
ORF1ab/nsp427I27MatAatG220.111111
ORF1ab/nsp427I27delATA---220.111111
ORF1ab/nsp427I27del2aTAa--22All0
ORF1ab/nsp427I27KaTaaAa22All0
ORF1ab/nsp427I27SaTAaGT22All0
ORF1ab/nsp427I27TaTaaCa22AY.1180.000125
ORF1ab/nsp427I27TaTaaCa22AY.1190.000071
ORF1ab/nsp427I27TaTaaCa22AY.130.000322
ORF1ab/nsp427I27TaTaaCa22AY.290.000032
ORF1ab/nsp427I27TaTaaCa22AY.390.000049
ORF1ab/nsp427I27delATA---22AY.430.000009
ORF1ab/nsp427I27LAtaCta22AY.430.000009
ORF1ab/nsp427I27VAtaGta22AY.430.000009
ORF1ab/nsp427I27VAtaGta22AY.440.000012
ORF1ab/nsp427I27LAtaCta22AY.440.000012
ORF1ab/nsp427I27TaTaaCa22AY.670.000929
ORF1ab/nsp427I27TaTaaCa22AY.750.000112
ORF1ab/nsp427I27TaTaaCa22AY.75.10.000361
ORF1ab/nsp427I27TaTaaCa22AY.9.20.000073
ORF1ab/nsp427I27delATA---22B.1.10.000036
ORF1ab/nsp427I27MatAatG22B.1.1.2430.008163
ORF1ab/nsp427I27TaTaaCa22B.1.1.3960.090909
ORF1ab/nsp427I27TaTaaCa22B.1.1.5190.000079
ORF1ab/nsp427I27del2aTAa--22B.1.1.70.000002
ORF1ab/nsp427I27VAtaGta22B.1.20.000018
ORF1ab/nsp427I27del1atAat-12B.1.20.000009
ORF1ab/nsp427I27del1AtACt-12B.1.20.000009
ORF1ab/nsp427I27TaTaaCa22B.1.3060.011429
ORF1ab/nsp427I27VAtaGta22B.1.617.20.000008
ORF1ab/nsp427I27delATA---22B.1.617.20.000008
ORF1ab/nsp427I27VAtaGta22C.36.30.001134
ORF1ab/nsp427I27TaTaaCa22D.20.00015
ORF1ab/nsp427I27LAtaCta22P.10.000032
ORF1ab/nsp427I27FAtATtT110.055556
ORF1ab/nsp427I27TaTaaCa11A0.000387
ORF1ab/nsp427I27IatAatC11A0.000387
ORF1ab/nsp427I27delATA---11A.2.40.003367
ORF1ab/nsp427I27FAtATtT11All0
ORF1ab/nsp427I27MatAatG11AY.1000.000046
ORF1ab/nsp427I27VAtaGta11AY.1010.00049
ORF1ab/nsp427I27LAtaCta11AY.1020.000027
ORF1ab/nsp427I27VAtaGta11AY.1020.000027
ORF1ab/nsp427I27LAtaCta11AY.1030.000006
ORF1ab/nsp427I27MatAatG11AY.1140.000231
ORF1ab/nsp427I27MatAatG11AY.1160.000287
ORF1ab/nsp427I27LAtaCta11AY.116.10.000311
ORF1ab/nsp427I27TaTaaCa11AY.23.10.000417
ORF1ab/nsp427I27delATA---11AY.250.000006
ORF1ab/nsp427I27VAtaGta11AY.260.000028
ORF1ab/nsp427I27TaTaaCa11AY.260.000028
ORF1ab/nsp427I27MatAatG11AY.270.000065
ORF1ab/nsp427I27IatAatT11AY.290.000016
ORF1ab/nsp427I27TaTaaCa11AY.3.10.000085
ORF1ab/nsp427I27IatAatT11AY.300.000396
ORF1ab/nsp427I27LAtaCta11AY.330.000067
ORF1ab/nsp427I27TaTaaCa11AY.360.000148
ORF1ab/nsp427I27LAtaCta11AY.390.000025
ORF1ab/nsp427I27TaTaaCa11AY.4.10.000737
ORF1ab/nsp427I27delATA---11AY.420.00004
ORF1ab/nsp427I27LAtaCta11AY.420.00004
ORF1ab/nsp427I27RaTaaGa11AY.430.000004
ORF1ab/nsp427I27TaTaaCa11AY.46.40.000165
ORF1ab/nsp427I27TaTaaCa11AY.50.000021
ORF1ab/nsp427I27delATA---11AY.50.000021
ORF1ab/nsp427I27TaTaaCa11AY.520.000814
ORF1ab/nsp427I27LAtaCta11AY.550.000917
ORF1ab/nsp427I27TaTaaCa11AY.550.000917
ORF1ab/nsp427I27TaTaaCa11AY.60.000041
ORF1ab/nsp427I27LAtaTta11AY.60.000041
ORF1ab/nsp427I27MatAatG11AY.60.000041
ORF1ab/nsp427I27KaTaaAa11AY.600.000938
ORF1ab/nsp427I27delATA---11AY.600.000938
ORF1ab/nsp427I27VAtaGta11AY.710.000475
ORF1ab/nsp427I27TaTaaCa11AY.850.000427
ORF1ab/nsp427I27TaTaaCa11AY.880.000884
ORF1ab/nsp427I27delATA---11AY.90.000068
ORF1ab/nsp427I27MatAatG11AY.90.000068
ORF1ab/nsp427I27LAtaCta11AY.9.20.000037
ORF1ab/nsp427I27TaTaaCa11AY.930.000273
ORF1ab/nsp427I27TaTaaCa11AY.940.000443
ORF1ab/nsp427I27TaTaaCa11AY.980.000079
ORF1ab/nsp427I27LAtaTta11B.10.000009
ORF1ab/nsp427I27del1atAat-11B.10.000009
ORF1ab/nsp427I27del1atAat-11B.1.10.000018
ORF1ab/nsp427I27TaTaaCa11B.1.10.000018
ORF1ab/nsp427I27MatAatG11B.1.10.000018
ORF1ab/nsp427I27LAtaTta11B.1.10.000018
ORF1ab/nsp427I27LAtaTta11B.1.1.250.000569
ORF1ab/nsp427I27delATA---11B.1.1.3060.000438
ORF1ab/nsp427I27LAtaTta11B.1.1.3060.000438
ORF1ab/nsp427I27VAtaGta11B.1.1.330.000421
ORF1ab/nsp427I27delATA---11B.1.1.4090.002833
ORF1ab/nsp427I27del1aTaa-a11B.1.1.4480.002033
ORF1ab/nsp427I27delATA---11B.1.1.460.004367
ORF1ab/nsp427I27del1atAat-11B.1.1.700.000341
ORF1ab/nsp427I27MatAatG11B.1.1390.000733
ORF1ab/nsp427I27TaTaaCa11B.1.1570.002985
ORF1ab/nsp427I27IatAatT11B.1.1770.000013
ORF1ab/nsp427I27VAtaGta11B.1.1770.000013
ORF1ab/nsp427I27del1atAat-11B.1.1770.000013
ORF1ab/nsp427I27delATA---11B.1.177.110.001698
ORF1ab/nsp427I27delATA---11B.1.177.210.000076
ORF1ab/nsp427I27VAtaGta11B.1.177.40.000211
ORF1ab/nsp427I27TaTaaCa11B.1.177.460.000918
ORF1ab/nsp427I27delATA---11B.1.177.630.002703
ORF1ab/nsp427I27TaTaaCa11B.1.177.70.000165
ORF1ab/nsp427I27delATA---11B.1.177.830.001481
ORF1ab/nsp427I27delATA---11B.1.230.006061
ORF1ab/nsp427I27delATA---11B.1.258.30.001675
ORF1ab/nsp427I27LAtaTta11B.1.3510.00003
ORF1ab/nsp427I27TaTaaCa11B.1.3510.00003
ORF1ab/nsp427I27VAtaGta11B.1.3510.00003
ORF1ab/nsp427I27del1atAat-11B.1.36.180.00042
ORF1ab/nsp427I27KaTaaAa11B.1.36.290.000517
ORF1ab/nsp427I27TaTaaCa11B.1.3960.000706
ORF1ab/nsp427I27TaTaaCa11B.1.4290.000024
ORF1ab/nsp427I27TaTaaCa11B.1.4590.004082
ORF1ab/nsp427I27LAtaCta11B.1.466.20.000391
ORF1ab/nsp427I27MatAatG11B.1.5260.000024
ORF1ab/nsp427I27VAtaGta11B.1.5770.000687
ORF1ab/nsp427I27TaTaaCa11B.1.617.10.000129
ORF1ab/nsp427I27IatAatC11B.1.617.20.000004
ORF1ab/nsp427I27TaTaaCa11B.1.6190.000871
ORF1ab/nsp427I27TaTaaCa11B.1.6250.002353
ORF1ab/nsp427I27delATA---11B.1.6300.005236
ORF1ab/nsp427I27LAtaTta11B.1.6370.000073
ORF1ab/nsp427I27RaTaaGa11C.350.000774
ORF1ab/nsp427I27TaTaaCa11C.360.000911
ORF1ab/nsp427I27TaTaaCa11C.36.30.000567
ORF1ab/nsp427I27VAtaGta11D.20.000075
ORF1ab/nsp427I27MatAatG11P.10.000016
ORF1ab/nsp427I27TaTaaCa11P.1.120.000484
ORF1ab/nsp427I27MatAatG11P.20.000187
ORF1ab/nsp427I27TaTaaCa11Q.10.000126
ORF1ab/nsp427I27delATA---11U.30.003861
ORF1ab/nsp427I27TaTaaCa11W.40.001351

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.