CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : CodonNum = 245

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4245N245NN3008NsynaaTaaC1047104719287-9289
ORF1ab/nsp4245N245delN3008deldelAAT---484819287-9289
ORF1ab/nsp4245N245HN3008HnonsynAatCat393919287-9289
ORF1ab/nsp4245N245TN3008TnonsynaAtaCt191919287-9289
ORF1ab/nsp4245N245SN3008SnonsynaAtaGt17160.9411769287-9289
ORF1ab/nsp4245N245SN3008SnonsynaATaGC1710.05882359287-9289
ORF1ab/nsp4245N245KN3008KnonsynaaTaaG15130.8666679287-9289
ORF1ab/nsp4245N245KN3008KnonsynaaTaaA1520.1333339287-9289
ORF1ab/nsp4245N245DN3008DnonsynAatGat9919287-9289
ORF1ab/nsp4245N245YN3008YnonsynAatTat6619287-9289
ORF1ab/nsp4245N245IN3008InonsynaAtaTt540.89287-9289
ORF1ab/nsp4245N245del1N3008del1delAat-at530.69287-9289
ORF1ab/nsp4245N245del1N3008del1delaaTaa-520.49287-9289
ORF1ab/nsp4245N245IN3008InonsynaATaTC510.29287-9289
ORF1ab/nsp4245N245CN3008CnonsynAAtTGt2219287-9289

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4245N245NaaTaaC10471047All0.0002
ORF1ab/nsp4245N245NaaTaaC547547C.300.944732
ORF1ab/nsp4245N245NaaTaaC168168B.1.1.5190.006671
ORF1ab/nsp4245N245NaaTaaC149149C.30.11
ORF1ab/nsp4245N245delAAT---4848All0.000009
ORF1ab/nsp4245N245NaaTaaC4646AY.50.00095
ORF1ab/nsp4245N245HAatCat3939All0.000007
ORF1ab/nsp4245N245HAatCat3434AY.40.000053
ORF1ab/nsp4245N245NaaTaaC3030B.1.1.70.000027
ORF1ab/nsp4245N245NaaTaaC2929B.1.617.20.000109
ORF1ab/nsp4245N245TaAtaCt1919All0.000004
ORF1ab/nsp4245N245SaAtaGt1617All0.000003
ORF1ab/nsp4245N245SaATaGC117All0
ORF1ab/nsp4245N245delAAT---1616B.1.1.70.000014
ORF1ab/nsp4245N245KaaTaaG1315All0.000002
ORF1ab/nsp4245N245KaaTaaA215All0
ORF1ab/nsp4245N245NaaTaaC1010B.1.3510.000297
ORF1ab/nsp4245N245DAatGat99All0.000002
ORF1ab/nsp4245N245NaaTaaC99B.10.000082
ORF1ab/nsp4245N245NaaTaaC88AY.430.000035
ORF1ab/nsp4245N245NaaTaaC88AY.440.000049
ORF1ab/nsp4245N245SaAtaGt67AY.440.000037
ORF1ab/nsp4245N245SaATaGC17AY.440.000006
ORF1ab/nsp4245N245YAatTat66All0.000001
ORF1ab/nsp4245N245IaAtaTt45All0.000001
ORF1ab/nsp4245N245del1Aat-at35All0.000001
ORF1ab/nsp4245N245del1aaTaa-25All0
ORF1ab/nsp4245N245IaATaTC15All0
ORF1ab/nsp4245N245DAatGat55AY.98.10.000242
ORF1ab/nsp4245N245TaAtaCt55B.1.1.70.000004
ORF1ab/nsp4245N245KaaTaaG55B.1.20.000044
ORF1ab/nsp4245N245HAatCat44AY.1200.000149
ORF1ab/nsp4245N245NaaTaaC44AY.200.000155
ORF1ab/nsp4245N245TaAtaCt44AY.430.000018
ORF1ab/nsp4245N245delAAT---44B.1.1770.000053
ORF1ab/nsp4245N245NaaTaaC44B.1.20.000035
ORF1ab/nsp4245N245NaaTaaC33AY.1030.000019
ORF1ab/nsp4245N245delAAT---33AY.40.000005
ORF1ab/nsp4245N245NaaTaaC33B.1.10.000054
ORF1ab/nsp4245N245NaaTaaC33B.1.1.3110.001074
ORF1ab/nsp4245N245SaAtaGt33B.1.1.70.000003
ORF1ab/nsp4245N245KaaTaaG33B.1.1.70.000003
ORF1ab/nsp4245N245del1Aat-at33B.1.20.000026
ORF1ab/nsp4245N245KaaTaaG33B.1.3670.002377
ORF1ab/nsp4245N245delAAT---33B.1.617.20.000011
ORF1ab/nsp4245N245CAAtTGt22All0
ORF1ab/nsp4245N245NaaTaaC22AY.250.000012
ORF1ab/nsp4245N245IaAtaTt22AY.260.000057
ORF1ab/nsp4245N245delAAT---22AY.350.000466
ORF1ab/nsp4245N245NaaTaaC22AY.390.000049
ORF1ab/nsp4245N245DAatGat22AY.40.000003
ORF1ab/nsp4245N245delAAT---22AY.4.50.000215
ORF1ab/nsp4245N245SaAtaGt22AY.430.000009
ORF1ab/nsp4245N245delAAT---22B.10.000018
ORF1ab/nsp4245N245TaAtaCt22B.1.617.20.000008
ORF1ab/nsp4245N245del1aaTaa-22B.1.6270.00404
ORF1ab/nsp4245N245TaAtaCt22C.370.000232
ORF1ab/nsp4245N245NaaTaaC22D.20.00015
ORF1ab/nsp4245N245YAatTat110.055556
ORF1ab/nsp4245N245NaaTaaC11A.30.002096
ORF1ab/nsp4245N245YAatTat11AY.1010.00049
ORF1ab/nsp4245N245SaAtaGt11AY.1020.000027
ORF1ab/nsp4245N245DAatGat11AY.1030.000006
ORF1ab/nsp4245N245SaAtaGt11AY.1070.000466
ORF1ab/nsp4245N245delAAT---11AY.1110.000183
ORF1ab/nsp4245N245delAAT---11AY.1200.000037
ORF1ab/nsp4245N245NaaTaaC11AY.120.2.10.000498
ORF1ab/nsp4245N245NaaTaaC11AY.130.000161
ORF1ab/nsp4245N245TaAtaCt11AY.200.000039
ORF1ab/nsp4245N245NaaTaaC11AY.290.000016
ORF1ab/nsp4245N245KaaTaaA11AY.330.000067
ORF1ab/nsp4245N245delAAT---11AY.360.000148
ORF1ab/nsp4245N245KaaTaaG11AY.40.000002
ORF1ab/nsp4245N245TaAtaCt11AY.40.000002
ORF1ab/nsp4245N245SaAtaGt11AY.4.20.000022
ORF1ab/nsp4245N245NaaTaaC11AY.420.00004
ORF1ab/nsp4245N245CAAtTGt11AY.440.000006
ORF1ab/nsp4245N245delAAT---11AY.460.000104
ORF1ab/nsp4245N245NaaTaaC11AY.510.000909
ORF1ab/nsp4245N245DAatGat11AY.690.000187
ORF1ab/nsp4245N245NaaTaaC11AY.750.000056
ORF1ab/nsp4245N245delAAT---11AY.75.10.00018
ORF1ab/nsp4245N245delAAT---11AY.810.001992
ORF1ab/nsp4245N245IaATaTC11AY.840.000437
ORF1ab/nsp4245N245delAAT---11AY.90.000068
ORF1ab/nsp4245N245NaaTaaC11AZ.30.00152
ORF1ab/nsp4245N245NaaTaaC11B0.000128
ORF1ab/nsp4245N245HAatCat11B.10.000009
ORF1ab/nsp4245N245IaAtaTt11B.10.000009
ORF1ab/nsp4245N245YAatTat11B.10.000009
ORF1ab/nsp4245N245KaaTaaG11B.1.10.000018
ORF1ab/nsp4245N245TaAtaCt11B.1.10.000018
ORF1ab/nsp4245N245delAAT---11B.1.10.000018
ORF1ab/nsp4245N245NaaTaaC11B.1.1.2140.000055
ORF1ab/nsp4245N245NaaTaaC11B.1.1.3720.000689
ORF1ab/nsp4245N245YAatTat11B.1.1.70.000001
ORF1ab/nsp4245N245delAAT---11B.1.177.510.004566
ORF1ab/nsp4245N245delAAT---11B.1.177.600.000218
ORF1ab/nsp4245N245delAAT---11B.1.177.760.002494
ORF1ab/nsp4245N245KaaTaaA11B.1.177.860.000183
ORF1ab/nsp4245N245delAAT---11B.1.20.000009
ORF1ab/nsp4245N245CAAtTGt11B.1.20.000009
ORF1ab/nsp4245N245YAatTat11B.1.20.000009
ORF1ab/nsp4245N245SaAtaGt11B.1.2060.000816
ORF1ab/nsp4245N245NaaTaaC11B.1.2210.000071
ORF1ab/nsp4245N245IaAtaTt11B.1.2400.000216
ORF1ab/nsp4245N245NaaTaaC11B.1.3690.000285
ORF1ab/nsp4245N245NaaTaaC11B.1.4290.000024
ORF1ab/nsp4245N245YAatTat11B.1.5170.000427
ORF1ab/nsp4245N245SaAtaGt11B.1.5750.000303
ORF1ab/nsp4245N245NaaTaaC11B.1.5820.000491
ORF1ab/nsp4245N245NaaTaaC11B.1.5880.00091
ORF1ab/nsp4245N245TaAtaCt11B.1.5950.000261
ORF1ab/nsp4245N245NaaTaaC11B.1.5960.000087
ORF1ab/nsp4245N245TaAtaCt11B.1.6370.000073
ORF1ab/nsp4245N245delAAT---11B.150.017544
ORF1ab/nsp4245N245delAAT---11B.340.013699
ORF1ab/nsp4245N245delAAT---11B.4.40.018868
ORF1ab/nsp4245N245TaAtaCt11C.37.10.002618
ORF1ab/nsp4245N245NaaTaaC11P.10.000016
ORF1ab/nsp4245N245delAAT---11P.10.000016
ORF1ab/nsp4245N245NaaTaaC11P.1.120.000484
ORF1ab/nsp4245N245NaaTaaC11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.