CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : CodonNum = 207

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4207E207EE2970EsyngaAgaG30430419173-9175
ORF1ab/nsp4207E207DE2970DnonsyngaAgaC1091030.9449549173-9175
ORF1ab/nsp4207E207DE2970DnonsyngaAgaT10960.05504599173-9175
ORF1ab/nsp4207E207del1E2970del1delGaa-aa80790.98759173-9175
ORF1ab/nsp4207E207del1E2970del1delgAag-a8010.01259173-9175
ORF1ab/nsp4207E207delE2970deldelGAA---585819173-9175
ORF1ab/nsp4207E207VE2970VnonsyngAagTa252519173-9175
ORF1ab/nsp4207E207GE2970GnonsyngAagGa232319173-9175
ORF1ab/nsp4207E207AE2970AnonsyngAagCa202019173-9175
ORF1ab/nsp4207E207XE2970XnonsynGaaTaa151519173-9175
ORF1ab/nsp4207E207QE2970QnonsynGaaCaa131319173-9175
ORF1ab/nsp4207E207KE2970KnonsynGaaAaa5519173-9175
ORF1ab/nsp4207E207NE2970NnonsynGaAAaC320.6666679173-9175
ORF1ab/nsp4207E207NE2970NnonsynGaAAaT310.3333339173-9175
ORF1ab/nsp4207E207HE2970HnonsynGaACaC2219173-9175

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4207E207EgaAgaG304304All0.000058
ORF1ab/nsp4207E207DgaAgaC103109All0.00002
ORF1ab/nsp4207E207DgaAgaT6109All0.000001
ORF1ab/nsp4207E207del1Gaa-aa7980All0.000015
ORF1ab/nsp4207E207del1gAag-a180All0
ORF1ab/nsp4207E207DgaAgaC7474AY.200.002876
ORF1ab/nsp4207E207del1Gaa-aa6666B.1.1.70.000059
ORF1ab/nsp4207E207delGAA---5858All0.000011
ORF1ab/nsp4207E207EgaAgaG5252B.1.1.70.000047
ORF1ab/nsp4207E207EgaAgaG5151AY.420.002052
ORF1ab/nsp4207E207EgaAgaG5050B.1.258.150.943396
ORF1ab/nsp4207E207VgAagTa2525All0.000005
ORF1ab/nsp4207E207GgAagGa2323All0.000004
ORF1ab/nsp4207E207delGAA---2323B.1.1.70.000021
ORF1ab/nsp4207E207EgaAgaG2121AY.30.000209
ORF1ab/nsp4207E207AgAagCa2020All0.000004
ORF1ab/nsp4207E207VgAagTa1919AY.30.000189
ORF1ab/nsp4207E207EgaAgaG1818B.1.2580.001198
ORF1ab/nsp4207E207EgaAgaG1818B.1.3670.014263
ORF1ab/nsp4207E207XGaaTaa1515All0.000003
ORF1ab/nsp4207E207QGaaCaa1313All0.000002
ORF1ab/nsp4207E207GgAagGa99AY.40.000014
ORF1ab/nsp4207E207EgaAgaG99B.1.617.20.000034
ORF1ab/nsp4207E207AgAagCa77AY.30.00007
ORF1ab/nsp4207E207EgaAgaG77AY.40.000011
ORF1ab/nsp4207E207DgaAgaC460.222222
ORF1ab/nsp4207E207DgaAgaT260.111111
ORF1ab/nsp4207E207AgAagCa66AY.1030.000037
ORF1ab/nsp4207E207EgaAgaG66B0.000767
ORF1ab/nsp4207E207GgAagGa66B.1.1.70.000005
ORF1ab/nsp4207E207KGaaAaa55All0.000001
ORF1ab/nsp4207E207EgaAgaG55AY.1000.00023
ORF1ab/nsp4207E207EgaAgaG55AY.250.00003
ORF1ab/nsp4207E207EgaAgaG55AY.50.000103
ORF1ab/nsp4207E207EgaAgaG44AY.290.000063
ORF1ab/nsp4207E207delGAA---44AY.4.50.00043
ORF1ab/nsp4207E207delGAA---44AY.430.000018
ORF1ab/nsp4207E207XGaaTaa44B.10.000037
ORF1ab/nsp4207E207EgaAgaG44B.10.000037
ORF1ab/nsp4207E207AgAagCa44B.1.1.70.000004
ORF1ab/nsp4207E207delGAA---44B.1.1770.000053
ORF1ab/nsp4207E207DgaAgaC44B.1.20.000035
ORF1ab/nsp4207E207NGaAAaC23All0
ORF1ab/nsp4207E207NGaAAaT13All0
ORF1ab/nsp4207E207EgaAgaG33AY.430.000013
ORF1ab/nsp4207E207DgaAgaC33AY.430.000013
ORF1ab/nsp4207E207QGaaCaa33B.10.000027
ORF1ab/nsp4207E207DgaAgaT23B.1.1.70.000002
ORF1ab/nsp4207E207DgaAgaC13B.1.1.70.000001
ORF1ab/nsp4207E207EgaAgaG33B.1.1770.00004
ORF1ab/nsp4207E207del1Gaa-aa33B.1.177.820.001432
ORF1ab/nsp4207E207del1Gaa-aa33B.1.3510.000089
ORF1ab/nsp4207E207EgaAgaG33B.6.60.002667
ORF1ab/nsp4207E207HGaACaC220.111111
ORF1ab/nsp4207E207EgaAgaG220.111111
ORF1ab/nsp4207E207NGaAAaC220.111111
ORF1ab/nsp4207E207DgaAgaC22A.2.20.003378
ORF1ab/nsp4207E207HGaACaC22All0
ORF1ab/nsp4207E207EgaAgaG22AY.230.000139
ORF1ab/nsp4207E207DgaAgaC12AY.250.000006
ORF1ab/nsp4207E207DgaAgaT12AY.250.000006
ORF1ab/nsp4207E207delGAA---22AY.40.000003
ORF1ab/nsp4207E207del1Gaa-aa22AY.520.001629
ORF1ab/nsp4207E207EgaAgaG22AY.60.000082
ORF1ab/nsp4207E207EgaAgaG22AY.740.000231
ORF1ab/nsp4207E207AgAagCa22B0.000256
ORF1ab/nsp4207E207DgaAgaC22B.1.1.2940.002532
ORF1ab/nsp4207E207QGaaCaa22B.1.1.70.000002
ORF1ab/nsp4207E207del1Gaa-aa22B.1.1600.000062
ORF1ab/nsp4207E207EgaAgaG22B.1.20.000018
ORF1ab/nsp4207E207EgaAgaG22B.1.3510.000059
ORF1ab/nsp4207E207DgaAgaC22B.1.36.290.001035
ORF1ab/nsp4207E207GgAagGa22B.1.4000.000858
ORF1ab/nsp4207E207EgaAgaG22B.1.4270.000101
ORF1ab/nsp4207E207EgaAgaG22B.1.5260.000047
ORF1ab/nsp4207E207EgaAgaG22B.1.6210.000177
ORF1ab/nsp4207E207DgaAgaC22B.1.6280.000705
ORF1ab/nsp4207E207XGaaTaa110.055556
ORF1ab/nsp4207E207GgAagGa110.055556
ORF1ab/nsp4207E207XGaaTaa11A0.000387
ORF1ab/nsp4207E207EgaAgaG11AY.1020.000027
ORF1ab/nsp4207E207DgaAgaC11AY.1030.000006
ORF1ab/nsp4207E207EgaAgaG11AY.1030.000006
ORF1ab/nsp4207E207GgAagGa11AY.1030.000006
ORF1ab/nsp4207E207delGAA---11AY.1200.000037
ORF1ab/nsp4207E207QGaaCaa11AY.140.000088
ORF1ab/nsp4207E207EgaAgaG11AY.200.000039
ORF1ab/nsp4207E207DgaAgaC11AY.260.000028
ORF1ab/nsp4207E207DgaAgaC11AY.290.000016
ORF1ab/nsp4207E207delGAA---11AY.30.00001
ORF1ab/nsp4207E207delGAA---11AY.330.000067
ORF1ab/nsp4207E207EgaAgaG11AY.350.000233
ORF1ab/nsp4207E207EgaAgaG11AY.39.10.00004
ORF1ab/nsp4207E207DgaAgaC11AY.40.000002
ORF1ab/nsp4207E207VgAagTa11AY.40.000002
ORF1ab/nsp4207E207AgAagCa11AY.40.000002
ORF1ab/nsp4207E207VgAagTa11AY.4.20.000022
ORF1ab/nsp4207E207XGaaTaa11AY.430.000004
ORF1ab/nsp4207E207EgaAgaG11AY.440.000006
ORF1ab/nsp4207E207del1gAag-a11AY.440.000006
ORF1ab/nsp4207E207XGaaTaa11AY.470.000031
ORF1ab/nsp4207E207EgaAgaG11AY.650.000533
ORF1ab/nsp4207E207GgAagGa11AY.770.001127
ORF1ab/nsp4207E207delGAA---11AY.780.001541
ORF1ab/nsp4207E207QGaaCaa11AY.80.000606
ORF1ab/nsp4207E207delGAA---11AY.950.000761
ORF1ab/nsp4207E207EgaAgaG11AY.950.000761
ORF1ab/nsp4207E207EgaAgaG11AY.98.10.000048
ORF1ab/nsp4207E207delGAA---11AY.990.001049
ORF1ab/nsp4207E207delGAA---11B0.000128
ORF1ab/nsp4207E207KGaaAaa11B.10.000009
ORF1ab/nsp4207E207delGAA---11B.10.000009
ORF1ab/nsp4207E207delGAA---11B.1.10.000018
ORF1ab/nsp4207E207XGaaTaa11B.1.10.000018
ORF1ab/nsp4207E207DgaAgaC11B.1.10.000018
ORF1ab/nsp4207E207EgaAgaG11B.1.10.000018
ORF1ab/nsp4207E207DgaAgaC11B.1.1.2220.000204
ORF1ab/nsp4207E207XGaaTaa11B.1.1.2530.002506
ORF1ab/nsp4207E207EgaAgaG11B.1.1.280.000311
ORF1ab/nsp4207E207DgaAgaT11B.1.1.3030.002762
ORF1ab/nsp4207E207delGAA---11B.1.1.3060.000438
ORF1ab/nsp4207E207EgaAgaG11B.1.1.3710.010417
ORF1ab/nsp4207E207QGaaCaa11B.1.1.390.00051
ORF1ab/nsp4207E207KGaaAaa11B.1.1.390.00051
ORF1ab/nsp4207E207delGAA---11B.1.1.4090.002833
ORF1ab/nsp4207E207GgAagGa11B.1.1.4340.000349
ORF1ab/nsp4207E207QGaaCaa11B.1.1.5190.00004
ORF1ab/nsp4207E207VgAagTa11B.1.1.70.000001
ORF1ab/nsp4207E207XGaaTaa11B.1.1200.007692
ORF1ab/nsp4207E207EgaAgaG11B.1.1600.000031
ORF1ab/nsp4207E207delGAA---11B.1.1600.000031
ORF1ab/nsp4207E207delGAA---11B.1.1610.017241
ORF1ab/nsp4207E207KGaaAaa11B.1.1770.000013
ORF1ab/nsp4207E207GgAagGa11B.1.1770.000013
ORF1ab/nsp4207E207delGAA---11B.1.177.40.000211
ORF1ab/nsp4207E207del1Gaa-aa11B.1.177.60.000977
ORF1ab/nsp4207E207EgaAgaG11B.1.177.600.000218
ORF1ab/nsp4207E207delGAA---11B.1.177.630.002703
ORF1ab/nsp4207E207GgAagGa11B.1.177.80.000752
ORF1ab/nsp4207E207XGaaTaa11B.1.177.820.000477
ORF1ab/nsp4207E207EgaAgaG11B.1.177.870.000728
ORF1ab/nsp4207E207KGaaAaa11B.1.20.000009
ORF1ab/nsp4207E207QGaaCaa11B.1.20.000009
ORF1ab/nsp4207E207XGaaTaa11B.1.20.000009
ORF1ab/nsp4207E207EgaAgaG11B.1.230.006061
ORF1ab/nsp4207E207EgaAgaG11B.1.2350.002519
ORF1ab/nsp4207E207delGAA---11B.1.2420.018868
ORF1ab/nsp4207E207QGaaCaa11B.1.2430.00007
ORF1ab/nsp4207E207del1Gaa-aa11B.1.36.10.00114
ORF1ab/nsp4207E207delGAA---11B.1.36.180.00042
ORF1ab/nsp4207E207delGAA---11B.1.36.380.001642
ORF1ab/nsp4207E207delGAA---11B.1.4150.014286
ORF1ab/nsp4207E207EgaAgaG11B.1.4290.000024
ORF1ab/nsp4207E207DgaAgaC11B.1.5260.000024
ORF1ab/nsp4207E207EgaAgaG11B.1.5460.003704
ORF1ab/nsp4207E207QGaaCaa11B.1.5750.000303
ORF1ab/nsp4207E207XGaaTaa11B.1.5960.000087
ORF1ab/nsp4207E207DgaAgaC11B.1.617.20.000004
ORF1ab/nsp4207E207delGAA---11B.1.617.20.000004
ORF1ab/nsp4207E207VgAagTa11B.1.617.20.000004
ORF1ab/nsp4207E207EgaAgaG11B.1.940.027027
ORF1ab/nsp4207E207delGAA---11B.150.017544
ORF1ab/nsp4207E207QGaaCaa11B.290.003509
ORF1ab/nsp4207E207NGaAAaT11C.350.000774
ORF1ab/nsp4207E207XGaaTaa11D.20.000075
ORF1ab/nsp4207E207VgAagTa11P.10.000016
ORF1ab/nsp4207E207EgaAgaG11P.10.000016
ORF1ab/nsp4207E207KGaaAaa11P.1.100.000269
ORF1ab/nsp4207E207VgAagTa11P.1.140.000048
ORF1ab/nsp4207E207EgaAgaG11P.1.170.000162
ORF1ab/nsp4207E207del1Gaa-aa11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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