CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : CodonNum = 177

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4177E177EE2940EsyngaAgaG8137813719083-9085
ORF1ab/nsp4177E177KE2940KnonsynGaaAaa868619083-9085
ORF1ab/nsp4177E177XE2940XnonsynGaaTaa82800.975619083-9085
ORF1ab/nsp4177E177XE2940XnonsynGAaTGa8220.02439029083-9085
ORF1ab/nsp4177E177delE2940deldelGAA---585819083-9085
ORF1ab/nsp4177E177GE2940GnonsyngAagGa51490.9607849083-9085
ORF1ab/nsp4177E177GE2940GnonsyngAAgGT5120.03921579083-9085
ORF1ab/nsp4177E177AE2940AnonsyngAagCa434319083-9085
ORF1ab/nsp4177E177DE2940DnonsyngaAgaC37320.8648659083-9085
ORF1ab/nsp4177E177DE2940DnonsyngaAgaT3750.1351359083-9085
ORF1ab/nsp4177E177HE2940HnonsynGaACaC161619083-9085
ORF1ab/nsp4177E177VE2940VnonsyngAagTa151519083-9085
ORF1ab/nsp4177E177QE2940QnonsynGaaCaa6619083-9085
ORF1ab/nsp4177E177del1E2940del1delGaa-aa630.59083-9085
ORF1ab/nsp4177E177del1E2940del1delgaAga-630.59083-9085
ORF1ab/nsp4177E177CE2940CnonsynGAATGT2219083-9085
ORF1ab/nsp4177E177YE2940YnonsynGaATaT2219083-9085
ORF1ab/nsp4177E177NE2940NnonsynGaAAaC1119083-9085
ORF1ab/nsp4177E177del2E2940del2delGAa--a1119083-9085

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4177E177EgaAgaG81378137All0.001556
ORF1ab/nsp4177E177EgaAgaG70427042B.1.20.062007
ORF1ab/nsp4177E177EgaAgaG227227B.1.1.70.000203
ORF1ab/nsp4177E177EgaAgaG195195B.1.5680.216667
ORF1ab/nsp4177E177EgaAgaG111111B.1.6360.744966
ORF1ab/nsp4177E177KGaaAaa8686All0.000016
ORF1ab/nsp4177E177XGaaTaa8082All0.000015
ORF1ab/nsp4177E177XGAaTGa282All0
ORF1ab/nsp4177E177EgaAgaG7272B.1.360.010505
ORF1ab/nsp4177E177EgaAgaG7070B.1.5960.0061
ORF1ab/nsp4177E177delGAA---5858All0.000011
ORF1ab/nsp4177E177EgaAgaG5252B.10.000476
ORF1ab/nsp4177E177GgAagGa4951All0.000009
ORF1ab/nsp4177E177GgAAgGT251All0
ORF1ab/nsp4177E177EgaAgaG4949Q.30.007107
ORF1ab/nsp4177E177AgAagCa4343All0.000008
ORF1ab/nsp4177E177EgaAgaG3838AY.530.010926
ORF1ab/nsp4177E177DgaAgaC3237All0.000006
ORF1ab/nsp4177E177DgaAgaT537All0.000001
ORF1ab/nsp4177E177AgAagCa3333AY.40.000051
ORF1ab/nsp4177E177XGaaTaa3232AY.40.00005
ORF1ab/nsp4177E177EgaAgaG3030B.1.10.000544
ORF1ab/nsp4177E177KGaaAaa2626AY.40.00004
ORF1ab/nsp4177E177XGaaTaa2323AY.4.50.002472
ORF1ab/nsp4177E177EgaAgaG2020P.10.000315
ORF1ab/nsp4177E177EgaAgaG1818AY.440.00011
ORF1ab/nsp4177E177delGAA---1818B.1.1.70.000016
ORF1ab/nsp4177E177HGaACaC1616All0.000003
ORF1ab/nsp4177E177KGaaAaa1616AY.250.000096
ORF1ab/nsp4177E177EgaAgaG1616AY.40.000025
ORF1ab/nsp4177E177VgAagTa1515All0.000003
ORF1ab/nsp4177E177EgaAgaG1515AY.1030.000093
ORF1ab/nsp4177E177EgaAgaG1414AY.9.20.000514
ORF1ab/nsp4177E177EgaAgaG1313AY.700.002711
ORF1ab/nsp4177E177DgaAgaC1313B.1.1.390.006626
ORF1ab/nsp4177E177EgaAgaG1212B.1.4270.000606
ORF1ab/nsp4177E177GgAagGa1010AY.250.00006
ORF1ab/nsp4177E177GgAagGa1010B.1.1.70.000009
ORF1ab/nsp4177E177EgaAgaG99B.1.4290.000212
ORF1ab/nsp4177E177HGaACaC88B.1.1.70.000007
ORF1ab/nsp4177E177EgaAgaG77AY.30.00007
ORF1ab/nsp4177E177EgaAgaG77AY.430.000031
ORF1ab/nsp4177E177KGaaAaa77AY.440.000043
ORF1ab/nsp4177E177EgaAgaG77B.1.1.2850.045752
ORF1ab/nsp4177E177HGaACaC77B.1.5250.000792
ORF1ab/nsp4177E177GgAagGa77B.1.5260.000165
ORF1ab/nsp4177E177EgaAgaG77B.1.5750.002124
ORF1ab/nsp4177E177QGaaCaa66All0.000001
ORF1ab/nsp4177E177del1gaAga-36All0.000001
ORF1ab/nsp4177E177del1Gaa-aa36All0.000001
ORF1ab/nsp4177E177delGAA---66AY.4.50.000645
ORF1ab/nsp4177E177delGAA---66AY.430.000027
ORF1ab/nsp4177E177EgaAgaG66B.1.1110.007051
ORF1ab/nsp4177E177EgaAgaG55AY.1190.000177
ORF1ab/nsp4177E177GgAagGa55AY.370.00158
ORF1ab/nsp4177E177EgaAgaG55AY.470.000156
ORF1ab/nsp4177E177KGaaAaa55AY.50.000103
ORF1ab/nsp4177E177XGaaTaa55AY.90.000338
ORF1ab/nsp4177E177EgaAgaG55B.1.617.20.000019
ORF1ab/nsp4177E177XGAaTGa240.111111
ORF1ab/nsp4177E177XGaaTaa240.111111
ORF1ab/nsp4177E177GgAAgGT240.111111
ORF1ab/nsp4177E177GgAagGa240.111111
ORF1ab/nsp4177E177KGaaAaa44AY.420.000161
ORF1ab/nsp4177E177XGaaTaa44AY.80.002424
ORF1ab/nsp4177E177VgAagTa44AY.9.10.000335
ORF1ab/nsp4177E177DgaAgaC44B.1.10.000073
ORF1ab/nsp4177E177EgaAgaG44B.1.6090.001918
ORF1ab/nsp4177E177KGaaAaa33AY.1200.000112
ORF1ab/nsp4177E177VgAagTa33AY.430.000013
ORF1ab/nsp4177E177EgaAgaG33AY.550.002752
ORF1ab/nsp4177E177EgaAgaG33AY.9.10.000251
ORF1ab/nsp4177E177XGaaTaa33B.10.000027
ORF1ab/nsp4177E177QGaaCaa33B.10.000027
ORF1ab/nsp4177E177delGAA---33B.1.1770.00004
ORF1ab/nsp4177E177GgAagGa33B.1.2430.000209
ORF1ab/nsp4177E177EgaAgaG33B.1.4160.003807
ORF1ab/nsp4177E177DgaAgaC33B.1.617.20.000011
ORF1ab/nsp4177E177EgaAgaG33B.1.6210.000266
ORF1ab/nsp4177E177DgaAgaT220.111111
ORF1ab/nsp4177E177CGAATGT220.111111
ORF1ab/nsp4177E177YGaATaT220.111111
ORF1ab/nsp4177E177KGaaAaa220.111111
ORF1ab/nsp4177E177GgAagGa22A.190.018868
ORF1ab/nsp4177E177EgaAgaG22AD.20.000438
ORF1ab/nsp4177E177CGAATGT22All0
ORF1ab/nsp4177E177YGaATaT22All0
ORF1ab/nsp4177E177DgaAgaC22AY.1030.000012
ORF1ab/nsp4177E177XGaaTaa22AY.1200.000074
ORF1ab/nsp4177E177EgaAgaG22AY.140.000176
ORF1ab/nsp4177E177EgaAgaG22AY.250.000012
ORF1ab/nsp4177E177EgaAgaG22AY.260.000057
ORF1ab/nsp4177E177EgaAgaG22AY.390.000049
ORF1ab/nsp4177E177delGAA---22AY.40.000003
ORF1ab/nsp4177E177GgAagGa22AY.40.000003
ORF1ab/nsp4177E177DgaAgaT12AY.40.000002
ORF1ab/nsp4177E177DgaAgaC12AY.40.000002
ORF1ab/nsp4177E177EgaAgaG22AY.4.20.000043
ORF1ab/nsp4177E177KGaaAaa22AY.4.50.000215
ORF1ab/nsp4177E177KGaaAaa22AY.430.000009
ORF1ab/nsp4177E177XGaaTaa22AY.580.001815
ORF1ab/nsp4177E177KGaaAaa22B.10.000018
ORF1ab/nsp4177E177delGAA---22B.1.10.000036
ORF1ab/nsp4177E177EgaAgaG22B.1.1.4340.000697
ORF1ab/nsp4177E177EgaAgaG22B.1.1.5190.000079
ORF1ab/nsp4177E177KGaaAaa22B.1.1.70.000002
ORF1ab/nsp4177E177DgaAgaC22B.1.1.70.000002
ORF1ab/nsp4177E177AgAagCa22B.1.1.70.000002
ORF1ab/nsp4177E177EgaAgaG22B.1.1770.000026
ORF1ab/nsp4177E177delGAA---22B.1.177.180.00232
ORF1ab/nsp4177E177EgaAgaG22B.1.177.330.003289
ORF1ab/nsp4177E177EgaAgaG22B.1.177.730.001133
ORF1ab/nsp4177E177AgAagCa22B.1.177.860.000367
ORF1ab/nsp4177E177KGaaAaa22B.1.20.000018
ORF1ab/nsp4177E177EgaAgaG22B.1.5260.000047
ORF1ab/nsp4177E177EgaAgaG22B.1.5670.006667
ORF1ab/nsp4177E177EgaAgaG22B.1.5950.000522
ORF1ab/nsp4177E177AgAagCa22B.1.5960.000174
ORF1ab/nsp4177E177KGaaAaa22B.1.617.20.000008
ORF1ab/nsp4177E177delGAA---22B.1.617.20.000008
ORF1ab/nsp4177E177VgAagTa22B.1.617.20.000008
ORF1ab/nsp4177E177EgaAgaG22B.310.007463
ORF1ab/nsp4177E177EgaAgaG22P.1.140.000096
ORF1ab/nsp4177E177EgaAgaG11A.23.10.000704
ORF1ab/nsp4177E177EgaAgaG11A.50.001923
ORF1ab/nsp4177E177XGaaTaa11AA.10.007246
ORF1ab/nsp4177E177del2GAa--a11All0
ORF1ab/nsp4177E177NGaAAaC11All0
ORF1ab/nsp4177E177KGaaAaa11AY.1020.000027
ORF1ab/nsp4177E177VgAagTa11AY.1030.000006
ORF1ab/nsp4177E177EgaAgaG11AY.1080.001103
ORF1ab/nsp4177E177EgaAgaG11AY.1130.000142
ORF1ab/nsp4177E177AgAagCa11AY.1190.000035
ORF1ab/nsp4177E177delGAA---11AY.1200.000037
ORF1ab/nsp4177E177QGaaCaa11AY.1200.000037
ORF1ab/nsp4177E177KGaaAaa11AY.120.10.000321
ORF1ab/nsp4177E177XGaaTaa11AY.170.008197
ORF1ab/nsp4177E177GgAagGa11AY.200.000039
ORF1ab/nsp4177E177EgaAgaG11AY.200.000039
ORF1ab/nsp4177E177AgAagCa11AY.250.000006
ORF1ab/nsp4177E177del1Gaa-aa11AY.250.000006
ORF1ab/nsp4177E177VgAagTa11AY.290.000016
ORF1ab/nsp4177E177DgaAgaC11AY.290.000016
ORF1ab/nsp4177E177DgaAgaC11AY.30.00001
ORF1ab/nsp4177E177delGAA---11AY.330.000067
ORF1ab/nsp4177E177GgAagGa11AY.34.10.00051
ORF1ab/nsp4177E177KGaaAaa11AY.390.000025
ORF1ab/nsp4177E177DgaAgaC11AY.39.10.00004
ORF1ab/nsp4177E177QGaaCaa11AY.40.000002
ORF1ab/nsp4177E177del1Gaa-aa11AY.40.000002
ORF1ab/nsp4177E177KGaaAaa11AY.410.000294
ORF1ab/nsp4177E177EgaAgaG11AY.420.00004
ORF1ab/nsp4177E177AgAagCa11AY.430.000004
ORF1ab/nsp4177E177DgaAgaC11AY.440.000006
ORF1ab/nsp4177E177del1gaAga-11AY.440.000006
ORF1ab/nsp4177E177KGaaAaa11AY.46.60.000072
ORF1ab/nsp4177E177VgAagTa11AY.470.000031
ORF1ab/nsp4177E177KGaaAaa11AY.490.003195
ORF1ab/nsp4177E177EgaAgaG11AY.50.000021
ORF1ab/nsp4177E177GgAagGa11AY.50.000021
ORF1ab/nsp4177E177delGAA---11AY.720.001361
ORF1ab/nsp4177E177EgaAgaG11AY.790.001211
ORF1ab/nsp4177E177XGaaTaa11AY.870.000833
ORF1ab/nsp4177E177delGAA---11AY.90.000068
ORF1ab/nsp4177E177delGAA---11AY.950.000761
ORF1ab/nsp4177E177EgaAgaG11B0.000128
ORF1ab/nsp4177E177delGAA---11B.10.000009
ORF1ab/nsp4177E177DgaAgaT11B.10.000009
ORF1ab/nsp4177E177VgAagTa11B.1.10.000018
ORF1ab/nsp4177E177QGaaCaa11B.1.10.000018
ORF1ab/nsp4177E177EgaAgaG11B.1.1.1220.045455
ORF1ab/nsp4177E177EgaAgaG11B.1.1.2220.000204
ORF1ab/nsp4177E177delGAA---11B.1.1.2320.001815
ORF1ab/nsp4177E177KGaaAaa11B.1.1.2840.000107
ORF1ab/nsp4177E177del1gaAga-11B.1.1.3060.000438
ORF1ab/nsp4177E177EgaAgaG11B.1.1.3110.000358
ORF1ab/nsp4177E177EgaAgaG11B.1.1.3620.005618
ORF1ab/nsp4177E177del1gaAga-11B.1.1.4090.002833
ORF1ab/nsp4177E177EgaAgaG11B.1.1.4170.002703
ORF1ab/nsp4177E177EgaAgaG11B.1.1.4620.008621
ORF1ab/nsp4177E177DgaAgaT11B.1.1.5190.00004
ORF1ab/nsp4177E177VgAagTa11B.1.1.70.000001
ORF1ab/nsp4177E177XGaaTaa11B.1.1.70.000001
ORF1ab/nsp4177E177KGaaAaa11B.1.1770.000013
ORF1ab/nsp4177E177VgAagTa11B.1.1770.000013
ORF1ab/nsp4177E177EgaAgaG11B.1.177.170.000821
ORF1ab/nsp4177E177delGAA---11B.1.177.40.000211
ORF1ab/nsp4177E177delGAA---11B.1.177.480.003125
ORF1ab/nsp4177E177delGAA---11B.1.177.630.002703
ORF1ab/nsp4177E177EgaAgaG11B.1.177.70.000165
ORF1ab/nsp4177E177GgAagGa11B.1.177.720.00339
ORF1ab/nsp4177E177EgaAgaG11B.1.1820.007246
ORF1ab/nsp4177E177GgAagGa11B.1.20.000009
ORF1ab/nsp4177E177delGAA---11B.1.20.000009
ORF1ab/nsp4177E177EgaAgaG11B.1.214.30.007143
ORF1ab/nsp4177E177EgaAgaG11B.1.2340.000132
ORF1ab/nsp4177E177delGAA---11B.1.2420.018868
ORF1ab/nsp4177E177EgaAgaG11B.1.2430.00007
ORF1ab/nsp4177E177EgaAgaG11B.1.2580.000067
ORF1ab/nsp4177E177KGaaAaa11B.1.3510.00003
ORF1ab/nsp4177E177delGAA---11B.1.36.170.000494
ORF1ab/nsp4177E177delGAA---11B.1.36.180.00042
ORF1ab/nsp4177E177DgaAgaC11B.1.36.210.00216
ORF1ab/nsp4177E177delGAA---11B.1.36.380.001642
ORF1ab/nsp4177E177EgaAgaG11B.1.3670.000792
ORF1ab/nsp4177E177delGAA---11B.1.3670.000792
ORF1ab/nsp4177E177DgaAgaC11B.1.4080.00369
ORF1ab/nsp4177E177EgaAgaG11B.1.4200.010417
ORF1ab/nsp4177E177DgaAgaC11B.1.4290.000024
ORF1ab/nsp4177E177EgaAgaG11B.1.466.20.000391
ORF1ab/nsp4177E177EgaAgaG11B.1.4730.019231
ORF1ab/nsp4177E177EgaAgaG11B.1.5500.013699
ORF1ab/nsp4177E177KGaaAaa11B.1.5640.000426
ORF1ab/nsp4177E177EgaAgaG11B.1.5820.000491
ORF1ab/nsp4177E177GgAagGa11B.1.5960.000087
ORF1ab/nsp4177E177XGaaTaa11B.1.5990.00365
ORF1ab/nsp4177E177EgaAgaG11B.1.6120.002653
ORF1ab/nsp4177E177del1Gaa-aa11B.1.617.10.000129
ORF1ab/nsp4177E177del2GAa--a11B.1.617.20.000004
ORF1ab/nsp4177E177XGaaTaa11B.1.617.20.000004
ORF1ab/nsp4177E177EgaAgaG11B.1.6280.000352
ORF1ab/nsp4177E177HGaACaC11B.1.6360.006711
ORF1ab/nsp4177E177EgaAgaG11B.1.6390.021739
ORF1ab/nsp4177E177delGAA---11B.150.017544
ORF1ab/nsp4177E177NGaAAaC11C.350.000774
ORF1ab/nsp4177E177EgaAgaG11C.360.000911
ORF1ab/nsp4177E177EgaAgaG11C.370.000116
ORF1ab/nsp4177E177EgaAgaG11D.20.000075
ORF1ab/nsp4177E177KGaaAaa11D.20.000075
ORF1ab/nsp4177E177AgAagCa11D.20.000075
ORF1ab/nsp4177E177GgAagGa11D.20.000075
ORF1ab/nsp4177E177XGaaTaa11D.20.000075
ORF1ab/nsp4177E177EgaAgaG11P.1.20.001156
ORF1ab/nsp4177E177EgaAgaG11P.20.000187
ORF1ab/nsp4177E177EgaAgaG11Q.10.000126
ORF1ab/nsp4177E177GgAagGa11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.