CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp4 : CodonNum = 173 & Codon = aAc

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp4173T173NT2936NnonsynaCcaAc888819071-9073

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp4173T173NaCcaAc8888All0.000017
ORF1ab/nsp4173T173NaCcaAc3333B.1.1.70.00003
ORF1ab/nsp4173T173NaCcaAc2626AY.440.000158
ORF1ab/nsp4173T173NaCcaAc1111AY.1010.005395
ORF1ab/nsp4173T173NaCcaAc44AY.430.000018
ORF1ab/nsp4173T173NaCcaAc33B.1.3510.000089
ORF1ab/nsp4173T173NaCcaAc22AY.1030.000012
ORF1ab/nsp4173T173NaCcaAc22B.1.617.20.000008
ORF1ab/nsp4173T173NaCcaAc11AY.130.000161
ORF1ab/nsp4173T173NaCcaAc11AY.30.00001
ORF1ab/nsp4173T173NaCcaAc11AY.300.000396
ORF1ab/nsp4173T173NaCcaAc11AY.60.000041
ORF1ab/nsp4173T173NaCcaAc11AY.750.000056
ORF1ab/nsp4173T173NaCcaAc11B.1.2400.000216
ORF1ab/nsp4173T173NaCcaAc11P.1.70.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.