CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = Y899H

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3899Y899HY1717HnonsynTacCac52500.9615385414-5416
ORF1ab/nsp3899Y899HY1717HnonsynTaCCaT5220.03846155414-5416

Details of the mutation Y899H within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3899Y899HTacCac5052All0.00001
ORF1ab/nsp3899Y899HTaCCaT252All0
ORF1ab/nsp3899Y899HTacCac2727AY.40.000042
ORF1ab/nsp3899Y899HTacCac44AY.30.00004
ORF1ab/nsp3899Y899HTacCac33B.1.617.20.000011
ORF1ab/nsp3899Y899HTacCac33P.10.000047
ORF1ab/nsp3899Y899HTacCac33P.1.140.000143
ORF1ab/nsp3899Y899HTacCac22B.10.000018
ORF1ab/nsp3899Y899HTacCac22B.1.1600.000062
ORF1ab/nsp3899Y899HTaCCaT22B.1.4110.007407
ORF1ab/nsp3899Y899HTacCac11A.2.40.003367
ORF1ab/nsp3899Y899HTacCac11AY.116.10.000311
ORF1ab/nsp3899Y899HTacCac11AY.250.000006
ORF1ab/nsp3899Y899HTacCac11B.1.1.70.000001
ORF1ab/nsp3899Y899HTacCac11B.1.1.700.000341
ORF1ab/nsp3899Y899HTacCac11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.