CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = Y817Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3817Y817YY1635YsyntaCtaT103841038415168-5170

Details of the mutation Y817Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3817Y817YtaCtaT1038410384All0.001986
ORF1ab/nsp3817Y817YtaCtaT66366636B.1.1770.08738
ORF1ab/nsp3817Y817YtaCtaT15151515B.1.177.150.955836
ORF1ab/nsp3817Y817YtaCtaT410410B.1.1.70.000367
ORF1ab/nsp3817Y817YtaCtaT164164B.1.177.141
ORF1ab/nsp3817Y817YtaCtaT135135AA.10.978261
ORF1ab/nsp3817Y817YtaCtaT129129AA.20.992308
ORF1ab/nsp3817Y817YtaCtaT110110AA.41
ORF1ab/nsp3817Y817YtaCtaT9999B.1.177.780.961165
ORF1ab/nsp3817Y817YtaCtaT8181B.1.5960.007058
ORF1ab/nsp3817Y817YtaCtaT7272AA.70.66055
ORF1ab/nsp3817Y817YtaCtaT7171AY.46.60.005127
ORF1ab/nsp3817Y817YtaCtaT6262AA.51
ORF1ab/nsp3817Y817YtaCtaT6262AA.61
ORF1ab/nsp3817Y817YtaCtaT5454AY.40.000084
ORF1ab/nsp3817Y817YtaCtaT5050B.10.000458
ORF1ab/nsp3817Y817YtaCtaT5050B.1.617.20.000188
ORF1ab/nsp3817Y817YtaCtaT4545AA.81
ORF1ab/nsp3817Y817YtaCtaT4242B.1.4290.000988
ORF1ab/nsp3817Y817YtaCtaT3737AA.31
ORF1ab/nsp3817Y817YtaCtaT3636B.1.160.300.107143
ORF1ab/nsp3817Y817YtaCtaT3030AY.330.002003
ORF1ab/nsp3817Y817YtaCtaT2525AY.30.000249
ORF1ab/nsp3817Y817YtaCtaT2424AY.250.000144
ORF1ab/nsp3817Y817YtaCtaT2121AY.430.000093
ORF1ab/nsp3817Y817YtaCtaT2020AY.4.2.10.00298
ORF1ab/nsp3817Y817YtaCtaT1717B.1.177.820.008115
ORF1ab/nsp3817Y817YtaCtaT1616A.10.00451
ORF1ab/nsp3817Y817YtaCtaT1515B.1.10.000272
ORF1ab/nsp3817Y817YtaCtaT1515B.1.20.000132
ORF1ab/nsp3817Y817YtaCtaT1515B.1.3110.004119
ORF1ab/nsp3817Y817YtaCtaT1414B.1.1600.000437
ORF1ab/nsp3817Y817YtaCtaT1313AY.1200.000483
ORF1ab/nsp3817Y817YtaCtaT1313AY.390.000321
ORF1ab/nsp3817Y817YtaCtaT1212AY.260.00034
ORF1ab/nsp3817Y817YtaCtaT1111B.1.2580.000732
ORF1ab/nsp3817Y817YtaCtaT1111P.10.000173
ORF1ab/nsp3817Y817YtaCtaT1010B.1.36.290.005173
ORF1ab/nsp3817Y817YtaCtaT99AY.1030.000056
ORF1ab/nsp3817Y817YtaCtaT99AY.1190.000318
ORF1ab/nsp3817Y817YtaCtaT99B.1.2210.000639
ORF1ab/nsp3817Y817YtaCtaT99B.1.438.10.000965
ORF1ab/nsp3817Y817YtaCtaT77AY.1180.000439
ORF1ab/nsp3817Y817YtaCtaT77AY.470.000218
ORF1ab/nsp3817Y817YtaCtaT77B.1.177.690.010386
ORF1ab/nsp3817Y817YtaCtaT77B.1.617.10.000903
ORF1ab/nsp3817Y817YtaCtaT77B.390.016317
ORF1ab/nsp3817Y817YtaCtaT77D.20.000525
ORF1ab/nsp3817Y817YtaCtaT66AY.1060.002009
ORF1ab/nsp3817Y817YtaCtaT66B0.000767
ORF1ab/nsp3817Y817YtaCtaT66B.1.177.620.007151
ORF1ab/nsp3817Y817YtaCtaT55AY.1020.000133
ORF1ab/nsp3817Y817YtaCtaT55AY.680.001369
ORF1ab/nsp3817Y817YtaCtaT55B.1.177.440.002595
ORF1ab/nsp3817Y817YtaCtaT44AY.1130.00057
ORF1ab/nsp3817Y817YtaCtaT44AY.4.20.000087
ORF1ab/nsp3817Y817YtaCtaT44AY.50.000083
ORF1ab/nsp3817Y817YtaCtaT44B.1.3510.000119
ORF1ab/nsp3817Y817YtaCtaT44C.370.000464
ORF1ab/nsp3817Y817YtaCtaT33AY.460.000312
ORF1ab/nsp3817Y817YtaCtaT33AY.700.000626
ORF1ab/nsp3817Y817YtaCtaT33B.1.1.1530.003286
ORF1ab/nsp3817Y817YtaCtaT33B.1.177.310.034483
ORF1ab/nsp3817Y817YtaCtaT33B.1.177.570.000843
ORF1ab/nsp3817Y817YtaCtaT33B.1.2010.017045
ORF1ab/nsp3817Y817YtaCtaT33B.1.258.170.000312
ORF1ab/nsp3817Y817YtaCtaT33B.1.6090.001438
ORF1ab/nsp3817Y817YtaCtaT33B.1.6210.000266
ORF1ab/nsp3817Y817YtaCtaT33P.1.140.000143
ORF1ab/nsp3817Y817YtaCtaT22AY.1090.001479
ORF1ab/nsp3817Y817YtaCtaT22AY.200.000078
ORF1ab/nsp3817Y817YtaCtaT22AY.230.000139
ORF1ab/nsp3817Y817YtaCtaT22AY.34.10.00102
ORF1ab/nsp3817Y817YtaCtaT22AY.46.30.001867
ORF1ab/nsp3817Y817YtaCtaT22AY.690.000373
ORF1ab/nsp3817Y817YtaCtaT22B.1.1.3060.000877
ORF1ab/nsp3817Y817YtaCtaT22B.1.177.40.000422
ORF1ab/nsp3817Y817YtaCtaT22B.1.177.400.010309
ORF1ab/nsp3817Y817YtaCtaT22B.1.177.540.001213
ORF1ab/nsp3817Y817YtaCtaT22B.1.177.650.001331
ORF1ab/nsp3817Y817YtaCtaT22B.1.2360.004107
ORF1ab/nsp3817Y817YtaCtaT22B.1.2400.000431
ORF1ab/nsp3817Y817YtaCtaT22B.1.4930.051282
ORF1ab/nsp3817Y817YtaCtaT22P.1.170.000324
ORF1ab/nsp3817Y817YtaCtaT11AD.20.000219
ORF1ab/nsp3817Y817YtaCtaT11AY.1000.000046
ORF1ab/nsp3817Y817YtaCtaT11AY.1210.000135
ORF1ab/nsp3817Y817YtaCtaT11AY.270.000065
ORF1ab/nsp3817Y817YtaCtaT11AY.290.000016
ORF1ab/nsp3817Y817YtaCtaT11AY.320.000532
ORF1ab/nsp3817Y817YtaCtaT11AY.370.000316
ORF1ab/nsp3817Y817YtaCtaT11AY.420.00004
ORF1ab/nsp3817Y817YtaCtaT11AY.440.000006
ORF1ab/nsp3817Y817YtaCtaT11AY.450.000122
ORF1ab/nsp3817Y817YtaCtaT11AY.46.40.000165
ORF1ab/nsp3817Y817YtaCtaT11AY.620.000436
ORF1ab/nsp3817Y817YtaCtaT11AY.710.000475
ORF1ab/nsp3817Y817YtaCtaT11AY.750.000056
ORF1ab/nsp3817Y817YtaCtaT11AY.75.10.00018
ORF1ab/nsp3817Y817YtaCtaT11AY.900.000684
ORF1ab/nsp3817Y817YtaCtaT11AY.930.000273
ORF1ab/nsp3817Y817YtaCtaT11AY.960.002075
ORF1ab/nsp3817Y817YtaCtaT11AY.980.000079
ORF1ab/nsp3817Y817YtaCtaT11AY.98.10.000048
ORF1ab/nsp3817Y817YtaCtaT11B.1.1.2160.00089
ORF1ab/nsp3817Y817YtaCtaT11B.1.1.2220.000204
ORF1ab/nsp3817Y817YtaCtaT11B.1.1.3150.008475
ORF1ab/nsp3817Y817YtaCtaT11B.1.1.3980.003226
ORF1ab/nsp3817Y817YtaCtaT11B.1.1.4090.002833
ORF1ab/nsp3817Y817YtaCtaT11B.1.1.4110.014706
ORF1ab/nsp3817Y817YtaCtaT11B.1.1.4860.001577
ORF1ab/nsp3817Y817YtaCtaT11B.1.1.5190.00004
ORF1ab/nsp3817Y817YtaCtaT11B.1.160.200.008929
ORF1ab/nsp3817Y817YtaCtaT11B.1.177.180.00116
ORF1ab/nsp3817Y817YtaCtaT11B.1.177.210.000076
ORF1ab/nsp3817Y817YtaCtaT11B.1.177.230.003236
ORF1ab/nsp3817Y817YtaCtaT11B.1.177.350.000691
ORF1ab/nsp3817Y817YtaCtaT11B.1.177.770.000726
ORF1ab/nsp3817Y817YtaCtaT11B.1.177.830.001481
ORF1ab/nsp3817Y817YtaCtaT11B.1.177.840.006667
ORF1ab/nsp3817Y817YtaCtaT11B.1.2410.000812
ORF1ab/nsp3817Y817YtaCtaT11B.1.2430.00007
ORF1ab/nsp3817Y817YtaCtaT11B.1.36.180.00042
ORF1ab/nsp3817Y817YtaCtaT11B.1.3620.001541
ORF1ab/nsp3817Y817YtaCtaT11B.1.3750.00082
ORF1ab/nsp3817Y817YtaCtaT11B.1.4160.001269
ORF1ab/nsp3817Y817YtaCtaT11B.1.416.10.001563
ORF1ab/nsp3817Y817YtaCtaT11B.1.4200.010417
ORF1ab/nsp3817Y817YtaCtaT11B.1.4270.00005
ORF1ab/nsp3817Y817YtaCtaT11B.1.5170.000427
ORF1ab/nsp3817Y817YtaCtaT11B.1.5760.000907
ORF1ab/nsp3817Y817YtaCtaT11B.350.007812
ORF1ab/nsp3817Y817YtaCtaT11B.400.000364
ORF1ab/nsp3817Y817YtaCtaT11N.30.005814
ORF1ab/nsp3817Y817YtaCtaT11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.