CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = Y719Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3719Y719YY1537YsyntaCtaT1150115014874-4876

Details of the mutation Y719Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3719Y719YtaCtaT11501150All0.00022
ORF1ab/nsp3719Y719YtaCtaT168168B.1.177.90.223702
ORF1ab/nsp3719Y719YtaCtaT146146B.1.177.40.030815
ORF1ab/nsp3719Y719YtaCtaT116116B.1.20.001021
ORF1ab/nsp3719Y719YtaCtaT109109B.1.1.70.000098
ORF1ab/nsp3719Y719YtaCtaT8686AY.430.000381
ORF1ab/nsp3719Y719YtaCtaT7070AY.1030.000435
ORF1ab/nsp3719Y719YtaCtaT6969B.1.243.21
ORF1ab/nsp3719Y719YtaCtaT4949B.1.617.20.000185
ORF1ab/nsp3719Y719YtaCtaT4242B.1.10.000762
ORF1ab/nsp3719Y719YtaCtaT4141AY.40.000064
ORF1ab/nsp3719Y719YtaCtaT4040B.10.000366
ORF1ab/nsp3719Y719YtaCtaT2424AY.250.000144
ORF1ab/nsp3719Y719YtaCtaT1616P.10.000252
ORF1ab/nsp3719Y719YtaCtaT1414B.1.2580.000932
ORF1ab/nsp3719Y719YtaCtaT1111AY.260.000311
ORF1ab/nsp3719Y719YtaCtaT1111AY.4.20.000239
ORF1ab/nsp3719Y719YtaCtaT77B.1.1600.000218
ORF1ab/nsp3719Y719YtaCtaT66AY.390.000148
ORF1ab/nsp3719Y719YtaCtaT66B.1.1770.000079
ORF1ab/nsp3719Y719YtaCtaT55AY.1180.000313
ORF1ab/nsp3719Y719YtaCtaT55AY.30.00005
ORF1ab/nsp3719Y719YtaCtaT55B.1.30.013089
ORF1ab/nsp3719Y719YtaCtaT44A.280.010582
ORF1ab/nsp3719Y719YtaCtaT44AY.1190.000141
ORF1ab/nsp3719Y719YtaCtaT44B.1.1.280.001245
ORF1ab/nsp3719Y719YtaCtaT44B.1.6370.000292
ORF1ab/nsp3719Y719YtaCtaT33AY.200.000117
ORF1ab/nsp3719Y719YtaCtaT33AY.440.000018
ORF1ab/nsp3719Y719YtaCtaT22AY.230.000139
ORF1ab/nsp3719Y719YtaCtaT22AY.23.10.000835
ORF1ab/nsp3719Y719YtaCtaT22AY.450.000243
ORF1ab/nsp3719Y719YtaCtaT22AY.470.000062
ORF1ab/nsp3719Y719YtaCtaT22B0.000256
ORF1ab/nsp3719Y719YtaCtaT22B.1.1.2300.018349
ORF1ab/nsp3719Y719YtaCtaT22B.1.1.5190.000079
ORF1ab/nsp3719Y719YtaCtaT22B.1.1700.008621
ORF1ab/nsp3719Y719YtaCtaT22B.1.177.320.002699
ORF1ab/nsp3719Y719YtaCtaT22B.1.2210.000142
ORF1ab/nsp3719Y719YtaCtaT22B.1.4270.000101
ORF1ab/nsp3719Y719YtaCtaT22B.1.4290.000047
ORF1ab/nsp3719Y719YtaCtaT22B.1.5960.000174
ORF1ab/nsp3719Y719YtaCtaT22C.370.000232
ORF1ab/nsp3719Y719YtaCtaT11AY.10.000396
ORF1ab/nsp3719Y719YtaCtaT11AY.1000.000046
ORF1ab/nsp3719Y719YtaCtaT11AY.1040.001984
ORF1ab/nsp3719Y719YtaCtaT11AY.1100.000113
ORF1ab/nsp3719Y719YtaCtaT11AY.1140.000231
ORF1ab/nsp3719Y719YtaCtaT11AY.1170.000085
ORF1ab/nsp3719Y719YtaCtaT11AY.1200.000037
ORF1ab/nsp3719Y719YtaCtaT11AY.240.000431
ORF1ab/nsp3719Y719YtaCtaT11AY.290.000016
ORF1ab/nsp3719Y719YtaCtaT11AY.300.000396
ORF1ab/nsp3719Y719YtaCtaT11AY.330.000067
ORF1ab/nsp3719Y719YtaCtaT11AY.340.000097
ORF1ab/nsp3719Y719YtaCtaT11AY.39.10.00004
ORF1ab/nsp3719Y719YtaCtaT11AY.4.50.000107
ORF1ab/nsp3719Y719YtaCtaT11AY.400.000964
ORF1ab/nsp3719Y719YtaCtaT11AY.460.000104
ORF1ab/nsp3719Y719YtaCtaT11AY.50.000021
ORF1ab/nsp3719Y719YtaCtaT11AY.700.000209
ORF1ab/nsp3719Y719YtaCtaT11AY.710.000475
ORF1ab/nsp3719Y719YtaCtaT11AY.75.10.00018
ORF1ab/nsp3719Y719YtaCtaT11AY.90.000068
ORF1ab/nsp3719Y719YtaCtaT11AY.98.10.000048
ORF1ab/nsp3719Y719YtaCtaT11AY.99.20.000092
ORF1ab/nsp3719Y719YtaCtaT11B.1.1.2140.000055
ORF1ab/nsp3719Y719YtaCtaT11B.1.1.2630.001558
ORF1ab/nsp3719Y719YtaCtaT11B.1.1.3020.002075
ORF1ab/nsp3719Y719YtaCtaT11B.1.1.330.000421
ORF1ab/nsp3719Y719YtaCtaT11B.1.1.390.00051
ORF1ab/nsp3719Y719YtaCtaT11B.1.160.300.002976
ORF1ab/nsp3719Y719YtaCtaT11B.1.177.230.003236
ORF1ab/nsp3719Y719YtaCtaT11B.1.177.560.000668
ORF1ab/nsp3719Y719YtaCtaT11B.1.177.80.000752
ORF1ab/nsp3719Y719YtaCtaT11B.1.2340.000132
ORF1ab/nsp3719Y719YtaCtaT11B.1.2360.002053
ORF1ab/nsp3719Y719YtaCtaT11B.1.258.170.000104
ORF1ab/nsp3719Y719YtaCtaT11B.1.258.210.007752
ORF1ab/nsp3719Y719YtaCtaT11B.1.36.270.000763
ORF1ab/nsp3719Y719YtaCtaT11B.1.3660.004878
ORF1ab/nsp3719Y719YtaCtaT11B.1.3690.000285
ORF1ab/nsp3719Y719YtaCtaT11B.1.438.10.000107
ORF1ab/nsp3719Y719YtaCtaT11B.1.5170.000427
ORF1ab/nsp3719Y719YtaCtaT11B.1.5260.000024
ORF1ab/nsp3719Y719YtaCtaT11B.1.5400.009709
ORF1ab/nsp3719Y719YtaCtaT11B.1.617.10.000129
ORF1ab/nsp3719Y719YtaCtaT11B.1.6210.000089
ORF1ab/nsp3719Y719YtaCtaT11C.350.000774
ORF1ab/nsp3719Y719YtaCtaT11C.36.30.000567
ORF1ab/nsp3719Y719YtaCtaT11D.20.000075
ORF1ab/nsp3719Y719YtaCtaT11P.1.150.000232
ORF1ab/nsp3719Y719YtaCtaT11P.1.70.000319
ORF1ab/nsp3719Y719YtaCtaT11P.20.000187
ORF1ab/nsp3719Y719YtaCtaT11P.30.001595
ORF1ab/nsp3719Y719YtaCtaT11P.70.004367
ORF1ab/nsp3719Y719YtaCtaT11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.