CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = Y356Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3356Y356YY1174YsyntaCtaT9105910513785-3787

Details of the mutation Y356Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3356Y356YtaCtaT91059105All0.001741
ORF1ab/nsp3356Y356YtaCtaT49414941B.1.1.70.004423
ORF1ab/nsp3356Y356YtaCtaT553553AY.46.60.039931
ORF1ab/nsp3356Y356YtaCtaT329329AY.30.003272
ORF1ab/nsp3356Y356YtaCtaT310310B.1.1.2980.267241
ORF1ab/nsp3356Y356YtaCtaT256256AY.40.000398
ORF1ab/nsp3356Y356YtaCtaT229229B.1.20.002016
ORF1ab/nsp3356Y356YtaCtaT162162B.1.617.20.00061
ORF1ab/nsp3356Y356YtaCtaT143143AY.440.00087
ORF1ab/nsp3356Y356YtaCtaT131131B.1.10.002376
ORF1ab/nsp3356Y356YtaCtaT9393AY.430.000412
ORF1ab/nsp3356Y356YtaCtaT9191B.1.1770.001198
ORF1ab/nsp3356Y356YtaCtaT8686P.1.140.004111
ORF1ab/nsp3356Y356YtaCtaT7777AY.250.000463
ORF1ab/nsp3356Y356YtaCtaT6969B.10.000632
ORF1ab/nsp3356Y356YtaCtaT6767AY.390.001656
ORF1ab/nsp3356Y356YtaCtaT6363B.570.954545
ORF1ab/nsp3356Y356YtaCtaT5555B.1.5610.021834
ORF1ab/nsp3356Y356YtaCtaT5454AY.690.01008
ORF1ab/nsp3356Y356YtaCtaT5252B.1.30.136126
ORF1ab/nsp3356Y356YtaCtaT4747AY.1030.000292
ORF1ab/nsp3356Y356YtaCtaT4343AY.360.006373
ORF1ab/nsp3356Y356YtaCtaT4141B.1.3510.001219
ORF1ab/nsp3356Y356YtaCtaT3737AY.1020.000981
ORF1ab/nsp3356Y356YtaCtaT3737AY.60.001522
ORF1ab/nsp3356Y356YtaCtaT3535AY.4.20.000759
ORF1ab/nsp3356Y356YtaCtaT3535P.20.006532
ORF1ab/nsp3356Y356YtaCtaT3434AY.290.000536
ORF1ab/nsp3356Y356YtaCtaT3434P.10.000536
ORF1ab/nsp3356Y356YtaCtaT2828AY.270.001812
ORF1ab/nsp3356Y356YtaCtaT2727B.1.1.4500.931034
ORF1ab/nsp3356Y356YtaCtaT2727B.1.5260.000635
ORF1ab/nsp3356Y356YtaCtaT2626AY.260.000736
ORF1ab/nsp3356Y356YtaCtaT2525B.1.1600.00078
ORF1ab/nsp3356Y356YtaCtaT2222B.1.2430.001531
ORF1ab/nsp3356Y356YtaCtaT2121B.1.177.810.003976
ORF1ab/nsp3356Y356YtaCtaT2020B.1.2320.010747
ORF1ab/nsp3356Y356YtaCtaT1919B0.002428
ORF1ab/nsp3356Y356YtaCtaT1919P.1.150.004414
ORF1ab/nsp3356Y356YtaCtaT1616AY.50.00033
ORF1ab/nsp3356Y356YtaCtaT1616B.1.1.500.010862
ORF1ab/nsp3356Y356YtaCtaT1414AY.200.000544
ORF1ab/nsp3356Y356YtaCtaT1414B.1.177.440.007265
ORF1ab/nsp3356Y356YtaCtaT1313AY.1200.000483
ORF1ab/nsp3356Y356YtaCtaT1313B.1.1.3650.072626
ORF1ab/nsp3356Y356YtaCtaT1313B.1.1.5190.000516
ORF1ab/nsp3356Y356YtaCtaT1313B.1.360.001897
ORF1ab/nsp3356Y356YtaCtaT1313B.1.5750.003944
ORF1ab/nsp3356Y356YtaCtaT1212B.1.4700.016854
ORF1ab/nsp3356Y356YtaCtaT1111AY.1000.000506
ORF1ab/nsp3356Y356YtaCtaT1111AY.460.001145
ORF1ab/nsp3356Y356YtaCtaT1111B.1.214.20.006595
ORF1ab/nsp3356Y356YtaCtaT1111B.1.2210.000781
ORF1ab/nsp3356Y356YtaCtaT1111B.1.2580.000732
ORF1ab/nsp3356Y356YtaCtaT1111B.1.4290.000259
ORF1ab/nsp3356Y356YtaCtaT1010AY.1190.000353
ORF1ab/nsp3356Y356YtaCtaT1010AY.470.000311
ORF1ab/nsp3356Y356YtaCtaT1010AY.960.020747
ORF1ab/nsp3356Y356YtaCtaT1010B.1.1.370.001929
ORF1ab/nsp3356Y356YtaCtaT1010B.1.4270.000505
ORF1ab/nsp3356Y356YtaCtaT1010B.1.5960.000871
ORF1ab/nsp3356Y356YtaCtaT1010Q.10.001263
ORF1ab/nsp3356Y356YtaCtaT99AY.1170.000761
ORF1ab/nsp3356Y356YtaCtaT99AY.1180.000564
ORF1ab/nsp3356Y356YtaCtaT99C.370.001045
ORF1ab/nsp3356Y356YtaCtaT99Q.80.001484
ORF1ab/nsp3356Y356YtaCtaT88B.1.1.1760.003515
ORF1ab/nsp3356Y356YtaCtaT88B.1.1.3060.003507
ORF1ab/nsp3356Y356YtaCtaT88B.1.2340.001056
ORF1ab/nsp3356Y356YtaCtaT88B.1.3610.010309
ORF1ab/nsp3356Y356YtaCtaT88Q.70.008889
ORF1ab/nsp3356Y356YtaCtaT77AY.1080.007718
ORF1ab/nsp3356Y356YtaCtaT77AY.230.000488
ORF1ab/nsp3356Y356YtaCtaT77AY.7.10.000789
ORF1ab/nsp3356Y356YtaCtaT77B.1.6210.00062
ORF1ab/nsp3356Y356YtaCtaT66A.23.10.004225
ORF1ab/nsp3356Y356YtaCtaT66AS.10.057143
ORF1ab/nsp3356Y356YtaCtaT66AY.330.000401
ORF1ab/nsp3356Y356YtaCtaT66AY.980.000474
ORF1ab/nsp3356Y356YtaCtaT66B.1.1.330.002525
ORF1ab/nsp3356Y356YtaCtaT66B.1.1.4330.008547
ORF1ab/nsp3356Y356YtaCtaT66B.1.5820.002944
ORF1ab/nsp3356Y356YtaCtaT66D.20.00045
ORF1ab/nsp3356Y356YtaCtaT66P.1.130.005391
ORF1ab/nsp3356Y356YtaCtaT66P.60.018868
ORF1ab/nsp3356Y356YtaCtaT55AY.1160.001434
ORF1ab/nsp3356Y356YtaCtaT55AY.130.000805
ORF1ab/nsp3356Y356YtaCtaT55AY.610.000524
ORF1ab/nsp3356Y356YtaCtaT55AY.9.20.000184
ORF1ab/nsp3356Y356YtaCtaT55B.1.1.1530.005476
ORF1ab/nsp3356Y356YtaCtaT55B.1.1460.021186
ORF1ab/nsp3356Y356YtaCtaT55B.1.177.500.023474
ORF1ab/nsp3356Y356YtaCtaT55B.1.3110.001373
ORF1ab/nsp3356Y356YtaCtaT55B.6.60.004444
ORF1ab/nsp3356Y356YtaCtaT44AY.1100.000451
ORF1ab/nsp3356Y356YtaCtaT44AY.1140.000924
ORF1ab/nsp3356Y356YtaCtaT44AY.1210.000541
ORF1ab/nsp3356Y356YtaCtaT44AY.3.10.000341
ORF1ab/nsp3356Y356YtaCtaT44AY.39.10.000158
ORF1ab/nsp3356Y356YtaCtaT44AY.450.000487
ORF1ab/nsp3356Y356YtaCtaT44AY.70.000784
ORF1ab/nsp3356Y356YtaCtaT44AY.90.00027
ORF1ab/nsp3356Y356YtaCtaT44AY.98.10.000194
ORF1ab/nsp3356Y356YtaCtaT44B.1.1.10.001307
ORF1ab/nsp3356Y356YtaCtaT44B.1.1.2550.012121
ORF1ab/nsp3356Y356YtaCtaT44B.1.1.2650.012618
ORF1ab/nsp3356Y356YtaCtaT44B.1.1.2690.005413
ORF1ab/nsp3356Y356YtaCtaT44B.1.1.280.001245
ORF1ab/nsp3356Y356YtaCtaT44B.1.1.3180.001207
ORF1ab/nsp3356Y356YtaCtaT44B.1.617.10.000516
ORF1ab/nsp3356Y356YtaCtaT44B.1.6370.000292
ORF1ab/nsp3356Y356YtaCtaT44Q.40.001819
ORF1ab/nsp3356Y356YtaCtaT33AY.1130.000427
ORF1ab/nsp3356Y356YtaCtaT33AY.340.000291
ORF1ab/nsp3356Y356YtaCtaT33AY.46.40.000494
ORF1ab/nsp3356Y356YtaCtaT33AY.700.000626
ORF1ab/nsp3356Y356YtaCtaT33AY.91.10.012195
ORF1ab/nsp3356Y356YtaCtaT33B.1.1.1330.025424
ORF1ab/nsp3356Y356YtaCtaT33B.1.1.2200.005576
ORF1ab/nsp3356Y356YtaCtaT33B.1.177.570.000843
ORF1ab/nsp3356Y356YtaCtaT33B.1.177.600.000655
ORF1ab/nsp3356Y356YtaCtaT33B.1.177.820.001432
ORF1ab/nsp3356Y356YtaCtaT33B.1.3400.012876
ORF1ab/nsp3356Y356YtaCtaT33B.1.3660.014634
ORF1ab/nsp3356Y356YtaCtaT33B.1.3690.000856
ORF1ab/nsp3356Y356YtaCtaT33B.1.5760.00272
ORF1ab/nsp3356Y356YtaCtaT33C.360.002732
ORF1ab/nsp3356Y356YtaCtaT33P.1.60.005837
ORF1ab/nsp3356Y356YtaCtaT22AD.20.000438
ORF1ab/nsp3356Y356YtaCtaT22AY.1050.001286
ORF1ab/nsp3356Y356YtaCtaT22AY.1060.00067
ORF1ab/nsp3356Y356YtaCtaT22AY.140.000176
ORF1ab/nsp3356Y356YtaCtaT22AY.34.10.00102
ORF1ab/nsp3356Y356YtaCtaT22AY.420.00008
ORF1ab/nsp3356Y356YtaCtaT22AY.46.10.002053
ORF1ab/nsp3356Y356YtaCtaT22AY.530.000575
ORF1ab/nsp3356Y356YtaCtaT22AY.620.000871
ORF1ab/nsp3356Y356YtaCtaT22AY.670.000929
ORF1ab/nsp3356Y356YtaCtaT22AY.740.000231
ORF1ab/nsp3356Y356YtaCtaT22AY.840.000875
ORF1ab/nsp3356Y356YtaCtaT22AY.9.10.000167
ORF1ab/nsp3356Y356YtaCtaT22AY.950.001522
ORF1ab/nsp3356Y356YtaCtaT22B.1.1.2160.001781
ORF1ab/nsp3356Y356YtaCtaT22B.1.1.2220.000408
ORF1ab/nsp3356Y356YtaCtaT22B.1.1.2430.008163
ORF1ab/nsp3356Y356YtaCtaT22B.1.1.2910.001485
ORF1ab/nsp3356Y356YtaCtaT22B.1.1.2940.002532
ORF1ab/nsp3356Y356YtaCtaT22B.1.1.3110.000716
ORF1ab/nsp3356Y356YtaCtaT22B.1.1.4090.005666
ORF1ab/nsp3356Y356YtaCtaT22B.1.1.4160.00181
ORF1ab/nsp3356Y356YtaCtaT22B.1.1.700.000682
ORF1ab/nsp3356Y356YtaCtaT22B.1.1110.00235
ORF1ab/nsp3356Y356YtaCtaT22B.1.177.540.001213
ORF1ab/nsp3356Y356YtaCtaT22B.1.177.70.00033
ORF1ab/nsp3356Y356YtaCtaT22B.1.177.750.002081
ORF1ab/nsp3356Y356YtaCtaT22B.1.2390.002442
ORF1ab/nsp3356Y356YtaCtaT22B.1.2400.000431
ORF1ab/nsp3356Y356YtaCtaT22B.1.3440.016393
ORF1ab/nsp3356Y356YtaCtaT22B.1.36.170.000988
ORF1ab/nsp3356Y356YtaCtaT22B.1.36.290.001035
ORF1ab/nsp3356Y356YtaCtaT22B.1.4000.000858
ORF1ab/nsp3356Y356YtaCtaT22B.1.5170.000854
ORF1ab/nsp3356Y356YtaCtaT22B.1.5250.000226
ORF1ab/nsp3356Y356YtaCtaT22B.1.5430.02
ORF1ab/nsp3356Y356YtaCtaT22B.1.5950.000522
ORF1ab/nsp3356Y356YtaCtaT22B.1.619.10.001283
ORF1ab/nsp3356Y356YtaCtaT22B.1.6200.001892
ORF1ab/nsp3356Y356YtaCtaT22B.1.621.10.001012
ORF1ab/nsp3356Y356YtaCtaT22B.40.004415
ORF1ab/nsp3356Y356YtaCtaT22B.400.000729
ORF1ab/nsp3356Y356YtaCtaT22B.60.00182
ORF1ab/nsp3356Y356YtaCtaT22P.1.40.001953
ORF1ab/nsp3356Y356YtaCtaT22Q.30.00029
ORF1ab/nsp3356Y356YtaCtaT110.055556
ORF1ab/nsp3356Y356YtaCtaT11AJ.10.045455
ORF1ab/nsp3356Y356YtaCtaT11AU.10.001266
ORF1ab/nsp3356Y356YtaCtaT11AY.1010.00049
ORF1ab/nsp3356Y356YtaCtaT11AY.1070.000466
ORF1ab/nsp3356Y356YtaCtaT11AY.1090.00074
ORF1ab/nsp3356Y356YtaCtaT11AY.120.10.000321
ORF1ab/nsp3356Y356YtaCtaT11AY.120.2.10.000498
ORF1ab/nsp3356Y356YtaCtaT11AY.160.00038
ORF1ab/nsp3356Y356YtaCtaT11AY.300.000396
ORF1ab/nsp3356Y356YtaCtaT11AY.350.000233
ORF1ab/nsp3356Y356YtaCtaT11AY.4.30.000842
ORF1ab/nsp3356Y356YtaCtaT11AY.4.50.000107
ORF1ab/nsp3356Y356YtaCtaT11AY.710.000475
ORF1ab/nsp3356Y356YtaCtaT11AY.750.000056
ORF1ab/nsp3356Y356YtaCtaT11AY.850.000427
ORF1ab/nsp3356Y356YtaCtaT11AY.910.00073
ORF1ab/nsp3356Y356YtaCtaT11AY.920.000287
ORF1ab/nsp3356Y356YtaCtaT11AY.99.20.000092
ORF1ab/nsp3356Y356YtaCtaT11B.1.1.2070.001182
ORF1ab/nsp3356Y356YtaCtaT11B.1.1.2140.000055
ORF1ab/nsp3356Y356YtaCtaT11B.1.1.250.000569
ORF1ab/nsp3356Y356YtaCtaT11B.1.1.2840.000107
ORF1ab/nsp3356Y356YtaCtaT11B.1.1.3010.001179
ORF1ab/nsp3356Y356YtaCtaT11B.1.1.3050.003861
ORF1ab/nsp3356Y356YtaCtaT11B.1.1.3780.007299
ORF1ab/nsp3356Y356YtaCtaT11B.1.1.3890.006061
ORF1ab/nsp3356Y356YtaCtaT11B.1.1.4520.111111
ORF1ab/nsp3356Y356YtaCtaT11B.1.1.5230.001563
ORF1ab/nsp3356Y356YtaCtaT11B.1.1.540.003021
ORF1ab/nsp3356Y356YtaCtaT11B.1.1.980.018519
ORF1ab/nsp3356Y356YtaCtaT11B.1.110.30.000718
ORF1ab/nsp3356Y356YtaCtaT11B.1.1570.002985
ORF1ab/nsp3356Y356YtaCtaT11B.1.160.80.001289
ORF1ab/nsp3356Y356YtaCtaT11B.1.177.150.000631
ORF1ab/nsp3356Y356YtaCtaT11B.1.177.190.001431
ORF1ab/nsp3356Y356YtaCtaT11B.1.177.200.001517
ORF1ab/nsp3356Y356YtaCtaT11B.1.177.210.000076
ORF1ab/nsp3356Y356YtaCtaT11B.1.177.40.000211
ORF1ab/nsp3356Y356YtaCtaT11B.1.177.790.002342
ORF1ab/nsp3356Y356YtaCtaT11B.1.177.860.000183
ORF1ab/nsp3356Y356YtaCtaT11B.1.258.170.000104
ORF1ab/nsp3356Y356YtaCtaT11B.1.2650.001271
ORF1ab/nsp3356Y356YtaCtaT11B.1.3200.001245
ORF1ab/nsp3356Y356YtaCtaT11B.1.3260.007576
ORF1ab/nsp3356Y356YtaCtaT11B.1.3430.020833
ORF1ab/nsp3356Y356YtaCtaT11B.1.3560.001727
ORF1ab/nsp3356Y356YtaCtaT11B.1.36.190.009259
ORF1ab/nsp3356Y356YtaCtaT11B.1.36.310.001751
ORF1ab/nsp3356Y356YtaCtaT11B.1.36.340.021277
ORF1ab/nsp3356Y356YtaCtaT11B.1.36.70.004
ORF1ab/nsp3356Y356YtaCtaT11B.1.36.80.001
ORF1ab/nsp3356Y356YtaCtaT11B.1.3990.001934
ORF1ab/nsp3356Y356YtaCtaT11B.1.4220.000812
ORF1ab/nsp3356Y356YtaCtaT11B.1.438.10.000107
ORF1ab/nsp3356Y356YtaCtaT11B.1.4560.003268
ORF1ab/nsp3356Y356YtaCtaT11B.1.466.20.000391
ORF1ab/nsp3356Y356YtaCtaT11B.1.4680.005714
ORF1ab/nsp3356Y356YtaCtaT11B.1.4800.002488
ORF1ab/nsp3356Y356YtaCtaT11B.1.4970.000315
ORF1ab/nsp3356Y356YtaCtaT11B.1.4990.00105
ORF1ab/nsp3356Y356YtaCtaT11B.1.5510.00129
ORF1ab/nsp3356Y356YtaCtaT11B.1.5650.00081
ORF1ab/nsp3356Y356YtaCtaT11B.1.5770.000687
ORF1ab/nsp3356Y356YtaCtaT11B.1.6180.004032
ORF1ab/nsp3356Y356YtaCtaT11B.1.6190.000871
ORF1ab/nsp3356Y356YtaCtaT11B.1.6230.000536
ORF1ab/nsp3356Y356YtaCtaT11B.1.6280.000352
ORF1ab/nsp3356Y356YtaCtaT11B.3.10.001658
ORF1ab/nsp3356Y356YtaCtaT11C.380.008065
ORF1ab/nsp3356Y356YtaCtaT11N.60.007092
ORF1ab/nsp3356Y356YtaCtaT11P.1.120.000484
ORF1ab/nsp3356Y356YtaCtaT11P.1.170.000162
ORF1ab/nsp3356Y356YtaCtaT11P.1.70.000319
ORF1ab/nsp3356Y356YtaCtaT11W.40.001351

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.