CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = Y1427Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31427Y1427YY2245YsyntaCtaT1093109316998-7000

Details of the mutation Y1427Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31427Y1427YtaCtaT10931093All0.000209
ORF1ab/nsp31427Y1427YtaCtaT406406AY.40.000632
ORF1ab/nsp31427Y1427YtaCtaT135135B.1.3510.004013
ORF1ab/nsp31427Y1427YtaCtaT8383AY.430.000368
ORF1ab/nsp31427Y1427YtaCtaT7070B.1.1.70.000063
ORF1ab/nsp31427Y1427YtaCtaT5454B.1.1.3470.981818
ORF1ab/nsp31427Y1427YtaCtaT3232AY.9.20.001175
ORF1ab/nsp31427Y1427YtaCtaT2727B.1.617.20.000102
ORF1ab/nsp31427Y1427YtaCtaT2222B.1.596.10.205607
ORF1ab/nsp31427Y1427YtaCtaT1818AY.1030.000112
ORF1ab/nsp31427Y1427YtaCtaT1414B.10.000128
ORF1ab/nsp31427Y1427YtaCtaT1010B.1.177.40.002111
ORF1ab/nsp31427Y1427YtaCtaT88AY.250.000048
ORF1ab/nsp31427Y1427YtaCtaT88AY.360.001186
ORF1ab/nsp31427Y1427YtaCtaT88AY.46.60.000578
ORF1ab/nsp31427Y1427YtaCtaT88B.1.10.000145
ORF1ab/nsp31427Y1427YtaCtaT88B.1.1.1700.009975
ORF1ab/nsp31427Y1427YtaCtaT77AY.1000.000322
ORF1ab/nsp31427Y1427YtaCtaT77AY.390.000173
ORF1ab/nsp31427Y1427YtaCtaT66AY.260.00017
ORF1ab/nsp31427Y1427YtaCtaT66AY.30.00006
ORF1ab/nsp31427Y1427YtaCtaT66AY.330.000401
ORF1ab/nsp31427Y1427YtaCtaT66P.1.10.001906
ORF1ab/nsp31427Y1427YtaCtaT55AY.440.00003
ORF1ab/nsp31427Y1427YtaCtaT55B.1.1.2140.000277
ORF1ab/nsp31427Y1427YtaCtaT55B.1.1.3180.001509
ORF1ab/nsp31427Y1427YtaCtaT55B.1.1600.000156
ORF1ab/nsp31427Y1427YtaCtaT55B.1.2430.000348
ORF1ab/nsp31427Y1427YtaCtaT55R.10.00045
ORF1ab/nsp31427Y1427YtaCtaT44AY.290.000063
ORF1ab/nsp31427Y1427YtaCtaT44AY.39.10.000158
ORF1ab/nsp31427Y1427YtaCtaT44B.1.360.000584
ORF1ab/nsp31427Y1427YtaCtaT44B.1.4290.000094
ORF1ab/nsp31427Y1427YtaCtaT44B.1.466.20.001565
ORF1ab/nsp31427Y1427YtaCtaT44B.1.617.10.000516
ORF1ab/nsp31427Y1427YtaCtaT33A.280.007937
ORF1ab/nsp31427Y1427YtaCtaT33AY.1130.000427
ORF1ab/nsp31427Y1427YtaCtaT33AY.1200.000112
ORF1ab/nsp31427Y1427YtaCtaT33AY.200.000117
ORF1ab/nsp31427Y1427YtaCtaT33AY.980.000237
ORF1ab/nsp31427Y1427YtaCtaT33AY.99.20.000276
ORF1ab/nsp31427Y1427YtaCtaT33B.1.1.390.001529
ORF1ab/nsp31427Y1427YtaCtaT33B.1.5260.000071
ORF1ab/nsp31427Y1427YtaCtaT33P.10.000047
ORF1ab/nsp31427Y1427YtaCtaT22AY.1020.000053
ORF1ab/nsp31427Y1427YtaCtaT22AY.1070.000932
ORF1ab/nsp31427Y1427YtaCtaT22AY.320.001065
ORF1ab/nsp31427Y1427YtaCtaT22AY.340.000194
ORF1ab/nsp31427Y1427YtaCtaT22AY.350.000466
ORF1ab/nsp31427Y1427YtaCtaT22AY.580.001815
ORF1ab/nsp31427Y1427YtaCtaT22AY.610.00021
ORF1ab/nsp31427Y1427YtaCtaT22B.1.1.10.000653
ORF1ab/nsp31427Y1427YtaCtaT22B.1.1.3370.007194
ORF1ab/nsp31427Y1427YtaCtaT22B.1.20.000018
ORF1ab/nsp31427Y1427YtaCtaT22B.1.3050.004301
ORF1ab/nsp31427Y1427YtaCtaT11A.2.50.000499
ORF1ab/nsp31427Y1427YtaCtaT11AY.1180.000063
ORF1ab/nsp31427Y1427YtaCtaT11AY.1190.000035
ORF1ab/nsp31427Y1427YtaCtaT11AY.1210.000135
ORF1ab/nsp31427Y1427YtaCtaT11AY.230.00007
ORF1ab/nsp31427Y1427YtaCtaT11AY.270.000065
ORF1ab/nsp31427Y1427YtaCtaT11AY.3.10.000085
ORF1ab/nsp31427Y1427YtaCtaT11AY.370.000316
ORF1ab/nsp31427Y1427YtaCtaT11AY.4.20.000022
ORF1ab/nsp31427Y1427YtaCtaT11AY.420.00004
ORF1ab/nsp31427Y1427YtaCtaT11AY.46.10.001027
ORF1ab/nsp31427Y1427YtaCtaT11AY.530.000288
ORF1ab/nsp31427Y1427YtaCtaT11AY.7.10.000113
ORF1ab/nsp31427Y1427YtaCtaT11AY.750.000056
ORF1ab/nsp31427Y1427YtaCtaT11B.1.1.100.001115
ORF1ab/nsp31427Y1427YtaCtaT11B.1.1.1170.009709
ORF1ab/nsp31427Y1427YtaCtaT11B.1.1.280.000311
ORF1ab/nsp31427Y1427YtaCtaT11B.1.1.3010.001179
ORF1ab/nsp31427Y1427YtaCtaT11B.1.1.3060.000438
ORF1ab/nsp31427Y1427YtaCtaT11B.1.1.330.000421
ORF1ab/nsp31427Y1427YtaCtaT11B.1.1.3480.000796
ORF1ab/nsp31427Y1427YtaCtaT11B.1.1.5190.00004
ORF1ab/nsp31427Y1427YtaCtaT11B.1.1770.000013
ORF1ab/nsp31427Y1427YtaCtaT11B.1.177.210.000076
ORF1ab/nsp31427Y1427YtaCtaT11B.1.177.70.000165
ORF1ab/nsp31427Y1427YtaCtaT11B.1.36.290.000517
ORF1ab/nsp31427Y1427YtaCtaT11B.1.3750.00082
ORF1ab/nsp31427Y1427YtaCtaT11B.1.4970.000315
ORF1ab/nsp31427Y1427YtaCtaT11B.1.5170.000427
ORF1ab/nsp31427Y1427YtaCtaT11B.1.5250.000113
ORF1ab/nsp31427Y1427YtaCtaT11B.1.5270.003704
ORF1ab/nsp31427Y1427YtaCtaT11B.1.5610.000397
ORF1ab/nsp31427Y1427YtaCtaT11B.1.5820.000491
ORF1ab/nsp31427Y1427YtaCtaT11B.1.6210.000089
ORF1ab/nsp31427Y1427YtaCtaT11B.1.621.10.000506
ORF1ab/nsp31427Y1427YtaCtaT11B.1.6280.000352
ORF1ab/nsp31427Y1427YtaCtaT11B.1.6370.000073
ORF1ab/nsp31427Y1427YtaCtaT11B.1.780.008547
ORF1ab/nsp31427Y1427YtaCtaT11C.230.005814
ORF1ab/nsp31427Y1427YtaCtaT11C.370.000116
ORF1ab/nsp31427Y1427YtaCtaT11P.1.120.000484

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.