CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = V766V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3766V766VV1584VsyngtGgtA157313060.8302615015-5017
ORF1ab/nsp3766V766VV1584VsyngtGgtT15732640.1678325015-5017
ORF1ab/nsp3766V766VV1584VsyngtGgtC157330.001907185015-5017

Details of the mutation V766V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3766V766VgtGgtA13061573All0.00025
ORF1ab/nsp3766V766VgtGgtT2641573All0.00005
ORF1ab/nsp3766V766VgtGgtC31573All0.000001
ORF1ab/nsp3766V766VgtGgtA863864AY.800.974041
ORF1ab/nsp3766V766VgtGgtT1864AY.800.001129
ORF1ab/nsp3766V766VgtGgtA116119AY.440.000706
ORF1ab/nsp3766V766VgtGgtT2119AY.440.000012
ORF1ab/nsp3766V766VgtGgtC1119AY.440.000006
ORF1ab/nsp3766V766VgtGgtA69103B.1.1.70.000062
ORF1ab/nsp3766V766VgtGgtT34103B.1.1.70.00003
ORF1ab/nsp3766V766VgtGgtT8083P.10.00126
ORF1ab/nsp3766V766VgtGgtA383P.10.000047
ORF1ab/nsp3766V766VgtGgtA4162AY.40.000064
ORF1ab/nsp3766V766VgtGgtT2162AY.40.000033
ORF1ab/nsp3766V766VgtGgtA4949AY.1020.001299
ORF1ab/nsp3766V766VgtGgtA2929B.1.5250.003282
ORF1ab/nsp3766V766VgtGgtT2828A.10.007892
ORF1ab/nsp3766V766VgtGgtA2222B.1.5260.000517
ORF1ab/nsp3766V766VgtGgtT1617AY.1030.000099
ORF1ab/nsp3766V766VgtGgtA117AY.1030.000006
ORF1ab/nsp3766V766VgtGgtA815B.1.617.20.00003
ORF1ab/nsp3766V766VgtGgtT715B.1.617.20.000026
ORF1ab/nsp3766V766VgtGgtA1114B.1.20.000097
ORF1ab/nsp3766V766VgtGgtT314B.1.20.000026
ORF1ab/nsp3766V766VgtGgtA99AY.60.00037
ORF1ab/nsp3766V766VgtGgtT68AY.250.000036
ORF1ab/nsp3766V766VgtGgtA28AY.250.000012
ORF1ab/nsp3766V766VgtGgtT68B.10.000055
ORF1ab/nsp3766V766VgtGgtA28B.10.000018
ORF1ab/nsp3766V766VgtGgtA58B.1.360.00073
ORF1ab/nsp3766V766VgtGgtT38B.1.360.000438
ORF1ab/nsp3766V766VgtGgtA77AY.1180.000439
ORF1ab/nsp3766V766VgtGgtA57AY.30.00005
ORF1ab/nsp3766V766VgtGgtT17AY.30.00001
ORF1ab/nsp3766V766VgtGgtC17AY.30.00001
ORF1ab/nsp3766V766VgtGgtA47B.1.10.000073
ORF1ab/nsp3766V766VgtGgtT37B.1.10.000054
ORF1ab/nsp3766V766VgtGgtA36AY.200.000117
ORF1ab/nsp3766V766VgtGgtT36AY.200.000117
ORF1ab/nsp3766V766VgtGgtT35B.1.1.5190.000119
ORF1ab/nsp3766V766VgtGgtA25B.1.1.5190.000079
ORF1ab/nsp3766V766VgtGgtT55B.1.177.40.001055
ORF1ab/nsp3766V766VgtGgtA55B.1.258.170.00052
ORF1ab/nsp3766V766VgtGgtA44AY.430.000018
ORF1ab/nsp3766V766VgtGgtT44B.1.3810.03125
ORF1ab/nsp3766V766VgtGgtA33AY.4.20.000065
ORF1ab/nsp3766V766VgtGgtT33AY.610.000314
ORF1ab/nsp3766V766VgtGgtA33B0.000383
ORF1ab/nsp3766V766VgtGgtA33B.1.2580.0002
ORF1ab/nsp3766V766VgtGgtA33B.1.438.10.000322
ORF1ab/nsp3766V766VgtGgtT22AY.1000.000092
ORF1ab/nsp3766V766VgtGgtA22AY.116.10.000623
ORF1ab/nsp3766V766VgtGgtA22AY.120.20.002571
ORF1ab/nsp3766V766VgtGgtT22AY.270.000129
ORF1ab/nsp3766V766VgtGgtA12AY.290.000016
ORF1ab/nsp3766V766VgtGgtT12AY.290.000016
ORF1ab/nsp3766V766VgtGgtA22AY.390.000049
ORF1ab/nsp3766V766VgtGgtT22AY.4.50.000215
ORF1ab/nsp3766V766VgtGgtA22B.1.1.250.001137
ORF1ab/nsp3766V766VgtGgtA22B.1.1.3180.000604
ORF1ab/nsp3766V766VgtGgtT22B.1.1770.000026
ORF1ab/nsp3766V766VgtGgtA22B.1.4700.002809
ORF1ab/nsp3766V766VgtGgtT12B.1.5960.000087
ORF1ab/nsp3766V766VgtGgtA12B.1.5960.000087
ORF1ab/nsp3766V766VgtGgtT12D.20.000075
ORF1ab/nsp3766V766VgtGgtC12D.20.000075
ORF1ab/nsp3766V766VgtGgtA12P.20.000187
ORF1ab/nsp3766V766VgtGgtT12P.20.000187
ORF1ab/nsp3766V766VgtGgtT11AY.10.000396
ORF1ab/nsp3766V766VgtGgtA11AY.1170.000085
ORF1ab/nsp3766V766VgtGgtA11AY.1190.000035
ORF1ab/nsp3766V766VgtGgtA11AY.1200.000037
ORF1ab/nsp3766V766VgtGgtT11AY.190.00114
ORF1ab/nsp3766V766VgtGgtA11AY.230.00007
ORF1ab/nsp3766V766VgtGgtA11AY.260.000028
ORF1ab/nsp3766V766VgtGgtA11AY.380.000499
ORF1ab/nsp3766V766VgtGgtA11AY.39.10.00004
ORF1ab/nsp3766V766VgtGgtT11AY.420.00004
ORF1ab/nsp3766V766VgtGgtT11AY.460.000104
ORF1ab/nsp3766V766VgtGgtA11AY.46.50.000198
ORF1ab/nsp3766V766VgtGgtT11AY.50.000021
ORF1ab/nsp3766V766VgtGgtT11AY.5.30.000337
ORF1ab/nsp3766V766VgtGgtT11AY.540.000095
ORF1ab/nsp3766V766VgtGgtT11AY.770.001127
ORF1ab/nsp3766V766VgtGgtA11AY.970.001701
ORF1ab/nsp3766V766VgtGgtA11AY.99.20.000092
ORF1ab/nsp3766V766VgtGgtA11B.1.1.2200.001859
ORF1ab/nsp3766V766VgtGgtT11B.1.1.2220.000204
ORF1ab/nsp3766V766VgtGgtA11B.1.1.3060.000438
ORF1ab/nsp3766V766VgtGgtA11B.1.1.500.000679
ORF1ab/nsp3766V766VgtGgtA11B.1.1600.000031
ORF1ab/nsp3766V766VgtGgtT11B.1.177.600.000218
ORF1ab/nsp3766V766VgtGgtT11B.1.177.790.002342
ORF1ab/nsp3766V766VgtGgtT11B.1.2210.000071
ORF1ab/nsp3766V766VgtGgtT11B.1.2430.00007
ORF1ab/nsp3766V766VgtGgtT11B.1.258.30.001675
ORF1ab/nsp3766V766VgtGgtT11B.1.3510.00003
ORF1ab/nsp3766V766VgtGgtT11B.1.36.100.004785
ORF1ab/nsp3766V766VgtGgtA11B.1.36.170.000494
ORF1ab/nsp3766V766VgtGgtA11B.1.3690.000285
ORF1ab/nsp3766V766VgtGgtA11B.1.4000.000429
ORF1ab/nsp3766V766VgtGgtT11B.1.4270.00005
ORF1ab/nsp3766V766VgtGgtT11B.1.4290.000024
ORF1ab/nsp3766V766VgtGgtT11B.1.5860.010989
ORF1ab/nsp3766V766VgtGgtT11B.1.6020.006536
ORF1ab/nsp3766V766VgtGgtA11B.1.6210.000089
ORF1ab/nsp3766V766VgtGgtT11B.60.00091
ORF1ab/nsp3766V766VgtGgtT11P.1.120.000484
ORF1ab/nsp3766V766VgtGgtA11P.1.140.000048
ORF1ab/nsp3766V766VgtGgtT11P.1.150.000232

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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