CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = V765V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3765V765VV1583VsyngtTgtC9699240.953565012-5014
ORF1ab/nsp3765V765VV1583VsyngtTgtA969320.03302375012-5014
ORF1ab/nsp3765V765VV1583VsyngtTgtG969130.01341595012-5014

Details of the mutation V765V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3765V765VgtTgtC924969All0.000177
ORF1ab/nsp3765V765VgtTgtA32969All0.000006
ORF1ab/nsp3765V765VgtTgtG13969All0.000002
ORF1ab/nsp3765V765VgtTgtC751751AY.360.111309
ORF1ab/nsp3765V765VgtTgtC2525B.1.1.500.016972
ORF1ab/nsp3765V765VgtTgtC1422B.1.1.70.000013
ORF1ab/nsp3765V765VgtTgtA522B.1.1.70.000004
ORF1ab/nsp3765V765VgtTgtG322B.1.1.70.000003
ORF1ab/nsp3765V765VgtTgtC2222B.1.617.20.000083
ORF1ab/nsp3765V765VgtTgtC1818AY.130.002898
ORF1ab/nsp3765V765VgtTgtA1717B.1.1.5250.092896
ORF1ab/nsp3765V765VgtTgtC1112AY.1030.000068
ORF1ab/nsp3765V765VgtTgtG112AY.1030.000006
ORF1ab/nsp3765V765VgtTgtC1010AY.40.000016
ORF1ab/nsp3765V765VgtTgtC99AY.250.000054
ORF1ab/nsp3765V765VgtTgtC77AY.20.002493
ORF1ab/nsp3765V765VgtTgtC55B.10.000046
ORF1ab/nsp3765V765VgtTgtC55B.1.1.3980.016129
ORF1ab/nsp3765V765VgtTgtC44AY.440.000024
ORF1ab/nsp3765V765VgtTgtA23AY.30.00002
ORF1ab/nsp3765V765VgtTgtC13AY.30.00001
ORF1ab/nsp3765V765VgtTgtC33AY.390.000074
ORF1ab/nsp3765V765VgtTgtC33AY.500.002398
ORF1ab/nsp3765V765VgtTgtC33AY.920.000862
ORF1ab/nsp3765V765VgtTgtC33B.1.20.000026
ORF1ab/nsp3765V765VgtTgtG22AY.1190.000071
ORF1ab/nsp3765V765VgtTgtC22AY.330.000134
ORF1ab/nsp3765V765VgtTgtC22AY.39.10.000079
ORF1ab/nsp3765V765VgtTgtG22AY.430.000009
ORF1ab/nsp3765V765VgtTgtC22AY.460.000208
ORF1ab/nsp3765V765VgtTgtA22B.1.177.810.000379
ORF1ab/nsp3765V765VgtTgtC22B.1.3510.000059
ORF1ab/nsp3765V765VgtTgtA22B.1.4270.000101
ORF1ab/nsp3765V765VgtTgtG22B.1.80.003945
ORF1ab/nsp3765V765VgtTgtC11AY.1000.000046
ORF1ab/nsp3765V765VgtTgtC11AY.230.00007
ORF1ab/nsp3765V765VgtTgtC11AY.260.000028
ORF1ab/nsp3765V765VgtTgtC11AY.340.000097
ORF1ab/nsp3765V765VgtTgtC11AY.4.40.000409
ORF1ab/nsp3765V765VgtTgtC11AY.5.30.000337
ORF1ab/nsp3765V765VgtTgtC11AY.730.000665
ORF1ab/nsp3765V765VgtTgtC11AY.790.001211
ORF1ab/nsp3765V765VgtTgtC11AY.90.000068
ORF1ab/nsp3765V765VgtTgtC11AY.970.001701
ORF1ab/nsp3765V765VgtTgtC11AY.980.000079
ORF1ab/nsp3765V765VgtTgtC11B0.000128
ORF1ab/nsp3765V765VgtTgtC11B.1.10.000018
ORF1ab/nsp3765V765VgtTgtC11B.1.1.1920.002309
ORF1ab/nsp3765V765VgtTgtC11B.1.1.2100.005714
ORF1ab/nsp3765V765VgtTgtC11B.1.1.4130.006897
ORF1ab/nsp3765V765VgtTgtC11B.1.1.4370.010417
ORF1ab/nsp3765V765VgtTgtG11B.1.1770.000013
ORF1ab/nsp3765V765VgtTgtA11B.1.214.30.007143
ORF1ab/nsp3765V765VgtTgtC11B.1.2230.002778
ORF1ab/nsp3765V765VgtTgtC11B.1.2340.000132
ORF1ab/nsp3765V765VgtTgtC11B.1.2580.000067
ORF1ab/nsp3765V765VgtTgtC11B.1.3690.000285
ORF1ab/nsp3765V765VgtTgtA11B.1.438.10.000107
ORF1ab/nsp3765V765VgtTgtA11B.1.5260.000024
ORF1ab/nsp3765V765VgtTgtC11B.1.5640.000426
ORF1ab/nsp3765V765VgtTgtG11B.1.5800.004065
ORF1ab/nsp3765V765VgtTgtA11B.1.6370.000073
ORF1ab/nsp3765V765VgtTgtG11D.20.000075

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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