CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = V597L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3597V597LV1415LnonsynGtgTtg1911850.9685864508-4510
ORF1ab/nsp3597V597LV1415LnonsynGtgCtg19150.0261784508-4510
ORF1ab/nsp3597V597LV1415LnonsynGtGCtC19110.00523564508-4510

Details of the mutation V597L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3597V597LGtgTtg185191All0.000035
ORF1ab/nsp3597V597LGtgCtg5191All0.000001
ORF1ab/nsp3597V597LGtGCtC1191All0
ORF1ab/nsp3597V597LGtgTtg7272AY.540.006865
ORF1ab/nsp3597V597LGtgTtg3232Q.30.004641
ORF1ab/nsp3597V597LGtgTtg78B.1.1.70.000006
ORF1ab/nsp3597V597LGtgCtg18B.1.1.70.000001
ORF1ab/nsp3597V597LGtgTtg88B.1.617.20.00003
ORF1ab/nsp3597V597LGtgTtg77AY.46.30.006536
ORF1ab/nsp3597V597LGtgTtg66AY.430.000027
ORF1ab/nsp3597V597LGtgTtg55AY.40.000008
ORF1ab/nsp3597V597LGtgTtg55B.10.000046
ORF1ab/nsp3597V597LGtgTtg44AY.390.000099
ORF1ab/nsp3597V597LGtgTtg33AY.1030.000019
ORF1ab/nsp3597V597LGtgTtg33AY.250.000018
ORF1ab/nsp3597V597LGtgTtg22AY.330.000134
ORF1ab/nsp3597V597LGtgTtg22AY.9.10.000167
ORF1ab/nsp3597V597LGtgTtg22B.1.20.000018
ORF1ab/nsp3597V597LGtgTtg22B.1.2400.000431
ORF1ab/nsp3597V597LGtgTtg22B.1.2580.000133
ORF1ab/nsp3597V597LGtgTtg22B.1.351.20.000605
ORF1ab/nsp3597V597LGtgTtg11AY.1020.000027
ORF1ab/nsp3597V597LGtgTtg11AY.140.000088
ORF1ab/nsp3597V597LGtgTtg11AY.23.10.000417
ORF1ab/nsp3597V597LGtgTtg11AY.260.000028
ORF1ab/nsp3597V597LGtgTtg11AY.340.000097
ORF1ab/nsp3597V597LGtgTtg11AY.39.10.00004
ORF1ab/nsp3597V597LGtgTtg11AY.440.000006
ORF1ab/nsp3597V597LGtgTtg11AY.450.000122
ORF1ab/nsp3597V597LGtgTtg11AY.460.000104
ORF1ab/nsp3597V597LGtgTtg11AY.470.000031
ORF1ab/nsp3597V597LGtgTtg11AY.610.000105
ORF1ab/nsp3597V597LGtgCtg11B.1.1.2200.001859
ORF1ab/nsp3597V597LGtgTtg11B.1.1600.000031
ORF1ab/nsp3597V597LGtgCtg11B.1.1770.000013
ORF1ab/nsp3597V597LGtgTtg11B.1.2060.000816
ORF1ab/nsp3597V597LGtgTtg11B.1.3240.001605
ORF1ab/nsp3597V597LGtgTtg11B.1.3510.00003
ORF1ab/nsp3597V597LGtgTtg11B.1.36.290.000517
ORF1ab/nsp3597V597LGtgTtg11B.1.3690.000285
ORF1ab/nsp3597V597LGtgCtg11B.1.5750.000303
ORF1ab/nsp3597V597LGtgTtg11B.1.6210.000089
ORF1ab/nsp3597V597LGtgTtg11B.1.6370.000073
ORF1ab/nsp3597V597LGtgCtg11B.1.690.035714
ORF1ab/nsp3597V597LGtGCtC11C.36.30.000567
ORF1ab/nsp3597V597LGtgTtg11D.20.000075
ORF1ab/nsp3597V597LGtgTtg11P.10.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.