CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = V477F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3477V477FV1295FnonsynGttTtt3931393114148-4150

Details of the mutation V477F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3477V477FGttTtt39313931All0.000752
ORF1ab/nsp3477V477FGttTtt17011701B.1.1.70.001523
ORF1ab/nsp3477V477FGttTtt244244P.10.003844
ORF1ab/nsp3477V477FGttTtt241241AY.40.000375
ORF1ab/nsp3477V477FGttTtt196196AY.440.001193
ORF1ab/nsp3477V477FGttTtt182182AY.430.000806
ORF1ab/nsp3477V477FGttTtt143143AY.260.004048
ORF1ab/nsp3477V477FGttTtt105105B.10.000962
ORF1ab/nsp3477V477FGttTtt104104B.1.20.000916
ORF1ab/nsp3477V477FGttTtt8484B.1.617.20.000316
ORF1ab/nsp3477V477FGttTtt6464AY.250.000385
ORF1ab/nsp3477V477FGttTtt6262AY.1030.000385
ORF1ab/nsp3477V477FGttTtt4747B.1.2340.006201
ORF1ab/nsp3477V477FGttTtt3232B.1.1770.000421
ORF1ab/nsp3477V477FGttTtt2929AY.1020.000769
ORF1ab/nsp3477V477FGttTtt2727AY.1170.002282
ORF1ab/nsp3477V477FGttTtt2525B.1.10.000454
ORF1ab/nsp3477V477FGttTtt2222B.1.2890.058511
ORF1ab/nsp3477V477FGttTtt2020A.20.013236
ORF1ab/nsp3477V477FGttTtt2020AY.1210.002706
ORF1ab/nsp3477V477FGttTtt2020B.1.1.4300.833333
ORF1ab/nsp3477V477FGttTtt1919AY.390.00047
ORF1ab/nsp3477V477FGttTtt1919Q.80.003133
ORF1ab/nsp3477V477FGttTtt1616B.1.221.20.064257
ORF1ab/nsp3477V477FGttTtt1414AY.98.10.000678
ORF1ab/nsp3477V477FGttTtt1313B.1.4500.147727
ORF1ab/nsp3477V477FGttTtt1212AY.200.000466
ORF1ab/nsp3477V477FGttTtt1212AY.4.20.00026
ORF1ab/nsp3477V477FGttTtt1212AY.570.007874
ORF1ab/nsp3477V477FGttTtt1212B.1.4590.04898
ORF1ab/nsp3477V477FGttTtt1212C.370.001393
ORF1ab/nsp3477V477FGttTtt1111AY.1190.000388
ORF1ab/nsp3477V477FGttTtt1111B.1.36.360.006623
ORF1ab/nsp3477V477FGttTtt1010AY.5.40.002767
ORF1ab/nsp3477V477FGttTtt1010B.1.5260.000235
ORF1ab/nsp3477V477FGttTtt1010P.20.001866
ORF1ab/nsp3477V477FGttTtt99AY.290.000142
ORF1ab/nsp3477V477FGttTtt99AY.590.004767
ORF1ab/nsp3477V477FGttTtt99B.1.438.10.000965
ORF1ab/nsp3477V477FGttTtt99B.60.008189
ORF1ab/nsp3477V477FGttTtt88AY.30.00008
ORF1ab/nsp3477V477FGttTtt88AY.9.10.00067
ORF1ab/nsp3477V477FGttTtt88B.1.3110.002197
ORF1ab/nsp3477V477FGttTtt77AY.4.30.005892
ORF1ab/nsp3477V477FGttTtt77AY.50.000145
ORF1ab/nsp3477V477FGttTtt77AY.540.000667
ORF1ab/nsp3477V477FGttTtt77B.1.1.4340.00244
ORF1ab/nsp3477V477FGttTtt77B.1.1.5190.000278
ORF1ab/nsp3477V477FGttTtt77B.1.177.210.000535
ORF1ab/nsp3477V477FGttTtt77B.1.5960.00061
ORF1ab/nsp3477V477FGttTtt77C.36.30.003971
ORF1ab/nsp3477V477FGttTtt66B.1.3510.000178
ORF1ab/nsp3477V477FGttTtt66P.1.10.001906
ORF1ab/nsp3477V477FGttTtt55AY.1200.000186
ORF1ab/nsp3477V477FGttTtt55AY.39.10.000198
ORF1ab/nsp3477V477FGttTtt44AY.120.10.001284
ORF1ab/nsp3477V477FGttTtt44AY.340.000388
ORF1ab/nsp3477V477FGttTtt44AY.4.50.00043
ORF1ab/nsp3477V477FGttTtt44AY.46.20.002541
ORF1ab/nsp3477V477FGttTtt44AY.470.000124
ORF1ab/nsp3477V477FGttTtt44AY.700.000834
ORF1ab/nsp3477V477FGttTtt44B.1.1.2630.006231
ORF1ab/nsp3477V477FGttTtt44B.1.1.3180.001207
ORF1ab/nsp3477V477FGttTtt44B.1.1.3980.012903
ORF1ab/nsp3477V477FGttTtt44B.1.1600.000125
ORF1ab/nsp3477V477FGttTtt44B.1.4970.001259
ORF1ab/nsp3477V477FGttTtt44D.20.0003
ORF1ab/nsp3477V477FGttTtt44P.1.150.000929
ORF1ab/nsp3477V477FGttTtt33A.10.000846
ORF1ab/nsp3477V477FGttTtt33AY.1040.005952
ORF1ab/nsp3477V477FGttTtt33AY.1180.000188
ORF1ab/nsp3477V477FGttTtt33AY.130.000483
ORF1ab/nsp3477V477FGttTtt33AY.140.000264
ORF1ab/nsp3477V477FGttTtt33AY.630.001161
ORF1ab/nsp3477V477FGttTtt33AY.750.000168
ORF1ab/nsp3477V477FGttTtt33AY.90.000203
ORF1ab/nsp3477V477FGttTtt33AZ.10.002602
ORF1ab/nsp3477V477FGttTtt33B.1.1.3450.130435
ORF1ab/nsp3477V477FGttTtt33B.1.2580.0002
ORF1ab/nsp3477V477FGttTtt33B.1.3750.002459
ORF1ab/nsp3477V477FGttTtt33B.1.4270.000151
ORF1ab/nsp3477V477FGttTtt33B.1.4660.069767
ORF1ab/nsp3477V477FGttTtt33P.1.160.001122
ORF1ab/nsp3477V477FGttTtt22A.2.50.000998
ORF1ab/nsp3477V477FGttTtt22A.2.5.20.003145
ORF1ab/nsp3477V477FGttTtt22AY.100.00106
ORF1ab/nsp3477V477FGttTtt22AY.1000.000092
ORF1ab/nsp3477V477FGttTtt22AY.230.000139
ORF1ab/nsp3477V477FGttTtt22AY.3.10.000171
ORF1ab/nsp3477V477FGttTtt22AY.420.00008
ORF1ab/nsp3477V477FGttTtt22AY.450.000243
ORF1ab/nsp3477V477FGttTtt22AY.46.60.000144
ORF1ab/nsp3477V477FGttTtt22AY.510.001818
ORF1ab/nsp3477V477FGttTtt22AY.60.000082
ORF1ab/nsp3477V477FGttTtt22AY.70.000392
ORF1ab/nsp3477V477FGttTtt22AY.75.10.000361
ORF1ab/nsp3477V477FGttTtt22AY.910.001461
ORF1ab/nsp3477V477FGttTtt22AY.920.000575
ORF1ab/nsp3477V477FGttTtt22B.1.1.10.000653
ORF1ab/nsp3477V477FGttTtt22B.1.1.1810.009091
ORF1ab/nsp3477V477FGttTtt22B.1.1.2160.001781
ORF1ab/nsp3477V477FGttTtt22B.1.1.2220.000408
ORF1ab/nsp3477V477FGttTtt22B.1.1.2250.014388
ORF1ab/nsp3477V477FGttTtt22B.1.1.280.000622
ORF1ab/nsp3477V477FGttTtt22B.1.1.3060.000877
ORF1ab/nsp3477V477FGttTtt22B.1.1.330.000842
ORF1ab/nsp3477V477FGttTtt22B.1.1.3330.002153
ORF1ab/nsp3477V477FGttTtt22B.1.177.810.000379
ORF1ab/nsp3477V477FGttTtt22B.1.2010.011364
ORF1ab/nsp3477V477FGttTtt22B.1.351.20.000605
ORF1ab/nsp3477V477FGttTtt22B.1.36.290.001035
ORF1ab/nsp3477V477FGttTtt22B.1.3900.021277
ORF1ab/nsp3477V477FGttTtt22B.1.4290.000047
ORF1ab/nsp3477V477FGttTtt22B.1.5750.000607
ORF1ab/nsp3477V477FGttTtt22B.1.5820.000981
ORF1ab/nsp3477V477FGttTtt22B.1.6210.000177
ORF1ab/nsp3477V477FGttTtt22C.1.20.008511
ORF1ab/nsp3477V477FGttTtt22C.350.001548
ORF1ab/nsp3477V477FGttTtt22P.1.100.000539
ORF1ab/nsp3477V477FGttTtt22P.1.140.000096
ORF1ab/nsp3477V477FGttTtt11A.2.5.30.010309
ORF1ab/nsp3477V477FGttTtt11AD.20.000219
ORF1ab/nsp3477V477FGttTtt11AY.1010.00049
ORF1ab/nsp3477V477FGttTtt11AY.1060.000335
ORF1ab/nsp3477V477FGttTtt11AY.1070.000466
ORF1ab/nsp3477V477FGttTtt11AY.1100.000113
ORF1ab/nsp3477V477FGttTtt11AY.1110.000183
ORF1ab/nsp3477V477FGttTtt11AY.160.00038
ORF1ab/nsp3477V477FGttTtt11AY.270.000065
ORF1ab/nsp3477V477FGttTtt11AY.34.10.00051
ORF1ab/nsp3477V477FGttTtt11AY.370.000316
ORF1ab/nsp3477V477FGttTtt11AY.4.40.000409
ORF1ab/nsp3477V477FGttTtt11AY.460.000104
ORF1ab/nsp3477V477FGttTtt11AY.46.50.000198
ORF1ab/nsp3477V477FGttTtt11AY.5.30.000337
ORF1ab/nsp3477V477FGttTtt11AY.650.000533
ORF1ab/nsp3477V477FGttTtt11AY.740.000116
ORF1ab/nsp3477V477FGttTtt11AY.840.000437
ORF1ab/nsp3477V477FGttTtt11AY.9.20.000037
ORF1ab/nsp3477V477FGttTtt11AY.99.20.000092
ORF1ab/nsp3477V477FGttTtt11B.1.1.2680.014925
ORF1ab/nsp3477V477FGttTtt11B.1.1.3110.000358
ORF1ab/nsp3477V477FGttTtt11B.1.1.3260.001761
ORF1ab/nsp3477V477FGttTtt11B.1.1.3540.004386
ORF1ab/nsp3477V477FGttTtt11B.1.1.3720.000689
ORF1ab/nsp3477V477FGttTtt11B.1.1.4320.001266
ORF1ab/nsp3477V477FGttTtt11B.1.1.5260.003546
ORF1ab/nsp3477V477FGttTtt11B.1.1.530.013699
ORF1ab/nsp3477V477FGttTtt11B.1.1110.001175
ORF1ab/nsp3477V477FGttTtt11B.1.1260.001276
ORF1ab/nsp3477V477FGttTtt11B.1.177.770.000726
ORF1ab/nsp3477V477FGttTtt11B.1.177.860.000183
ORF1ab/nsp3477V477FGttTtt11B.1.214.20.0006
ORF1ab/nsp3477V477FGttTtt11B.1.2390.001221
ORF1ab/nsp3477V477FGttTtt11B.1.2410.000812
ORF1ab/nsp3477V477FGttTtt11B.1.3360.002439
ORF1ab/nsp3477V477FGttTtt11B.1.3490.000715
ORF1ab/nsp3477V477FGttTtt11B.1.360.000146
ORF1ab/nsp3477V477FGttTtt11B.1.36.80.001
ORF1ab/nsp3477V477FGttTtt11B.1.3660.004878
ORF1ab/nsp3477V477FGttTtt11B.1.4010.008197
ORF1ab/nsp3477V477FGttTtt11B.1.4090.000781
ORF1ab/nsp3477V477FGttTtt11B.1.4380.006536
ORF1ab/nsp3477V477FGttTtt11B.1.4410.009615
ORF1ab/nsp3477V477FGttTtt11B.1.466.20.000391
ORF1ab/nsp3477V477FGttTtt11B.1.5030.002488
ORF1ab/nsp3477V477FGttTtt11B.1.5090.000866
ORF1ab/nsp3477V477FGttTtt11B.1.5250.000113
ORF1ab/nsp3477V477FGttTtt11B.1.5300.007143
ORF1ab/nsp3477V477FGttTtt11B.1.5380.008065
ORF1ab/nsp3477V477FGttTtt11B.1.5600.00463
ORF1ab/nsp3477V477FGttTtt11B.1.5680.001111
ORF1ab/nsp3477V477FGttTtt11B.1.5950.000261
ORF1ab/nsp3477V477FGttTtt11B.1.6230.000536
ORF1ab/nsp3477V477FGttTtt11B.1.6280.000352
ORF1ab/nsp3477V477FGttTtt11B.1.6370.000073
ORF1ab/nsp3477V477FGttTtt11B.400.000364
ORF1ab/nsp3477V477FGttTtt11C.180.002591
ORF1ab/nsp3477V477FGttTtt11C.360.000911
ORF1ab/nsp3477V477FGttTtt11C.37.10.002618
ORF1ab/nsp3477V477FGttTtt11P.1.120.000484

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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