CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = V393F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3393V393FV1211FnonsynGttTtt243124300.9995893896-3898
ORF1ab/nsp3393V393FV1211FnonsynGtTTtC243110.0004113533896-3898

Details of the mutation V393F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3393V393FGttTtt24302431All0.000465
ORF1ab/nsp3393V393FGtTTtC12431All0
ORF1ab/nsp3393V393FGttTtt497497AY.40.000774
ORF1ab/nsp3393V393FGttTtt269269AY.440.001637
ORF1ab/nsp3393V393FGttTtt266266B.1.1.70.000238
ORF1ab/nsp3393V393FGttTtt208208AY.460.021649
ORF1ab/nsp3393V393FGttTtt127127B.1.1.2000.947761
ORF1ab/nsp3393V393FGttTtt8787B.1.617.20.000328
ORF1ab/nsp3393V393FGttTtt7474AY.1030.000459
ORF1ab/nsp3393V393FGttTtt6969P.1.100.018593
ORF1ab/nsp3393V393FGttTtt6666P.20.012318
ORF1ab/nsp3393V393FGttTtt5555AY.260.001557
ORF1ab/nsp3393V393FGttTtt5555AY.430.000244
ORF1ab/nsp3393V393FGttTtt5050AN.11
ORF1ab/nsp3393V393FGttTtt3939AY.290.000615
ORF1ab/nsp3393V393FGttTtt3838B.1.4290.000894
ORF1ab/nsp3393V393FGttTtt3434AY.250.000205
ORF1ab/nsp3393V393FGttTtt3233B.1.1770.000421
ORF1ab/nsp3393V393FGtTTtC133B.1.1770.000013
ORF1ab/nsp3393V393FGttTtt3131AY.200.001205
ORF1ab/nsp3393V393FGttTtt2727B.1.20.000238
ORF1ab/nsp3393V393FGttTtt2626D.20.001951
ORF1ab/nsp3393V393FGttTtt2323B.1.596.10.214953
ORF1ab/nsp3393V393FGttTtt2222P.10.000347
ORF1ab/nsp3393V393FGttTtt1616AY.1020.000424
ORF1ab/nsp3393V393FGttTtt1616AY.390.000395
ORF1ab/nsp3393V393FGttTtt1616B.1.10.00029
ORF1ab/nsp3393V393FGttTtt1414AY.30.000139
ORF1ab/nsp3393V393FGttTtt1414AY.4.20.000304
ORF1ab/nsp3393V393FGttTtt1313B.10.000119
ORF1ab/nsp3393V393FGttTtt1212B.1.1.1960.068571
ORF1ab/nsp3393V393FGttTtt1010B.1.1.250.005685
ORF1ab/nsp3393V393FGttTtt1010B.1.360.001459
ORF1ab/nsp3393V393FGttTtt1010P.1.150.002323
ORF1ab/nsp3393V393FGttTtt99AY.380.004493
ORF1ab/nsp3393V393FGttTtt99B.1.3510.000268
ORF1ab/nsp3393V393FGttTtt66AY.360.000889
ORF1ab/nsp3393V393FGttTtt66AY.750.000336
ORF1ab/nsp3393V393FGttTtt66B.1.36.290.003104
ORF1ab/nsp3393V393FGttTtt55B.1.6210.000443
ORF1ab/nsp3393V393FGttTtt44AY.420.000161
ORF1ab/nsp3393V393FGttTtt44AY.610.000419
ORF1ab/nsp3393V393FGttTtt44AY.90.00027
ORF1ab/nsp3393V393FGttTtt44B.1.1.120.029851
ORF1ab/nsp3393V393FGttTtt44B.1.1600.000125
ORF1ab/nsp3393V393FGttTtt44B.1.5250.000453
ORF1ab/nsp3393V393FGttTtt44P.1.140.000191
ORF1ab/nsp3393V393FGttTtt33AY.160.001139
ORF1ab/nsp3393V393FGttTtt33AY.330.0002
ORF1ab/nsp3393V393FGttTtt33AY.39.10.000119
ORF1ab/nsp3393V393FGttTtt33AY.75.10.000541
ORF1ab/nsp3393V393FGttTtt33AY.770.003382
ORF1ab/nsp3393V393FGttTtt33B.1.1.2210.030303
ORF1ab/nsp3393V393FGttTtt33B.1.1.2840.000322
ORF1ab/nsp3393V393FGttTtt33B.1.2210.000213
ORF1ab/nsp3393V393FGttTtt33B.1.2430.000209
ORF1ab/nsp3393V393FGttTtt33B.1.2580.0002
ORF1ab/nsp3393V393FGttTtt33B.1.3690.000856
ORF1ab/nsp3393V393FGttTtt33B.1.5260.000071
ORF1ab/nsp3393V393FGttTtt33Q.80.000495
ORF1ab/nsp3393V393FGttTtt22AY.1000.000092
ORF1ab/nsp3393V393FGttTtt22AY.1060.00067
ORF1ab/nsp3393V393FGttTtt22AY.1200.000074
ORF1ab/nsp3393V393FGttTtt22AY.4.50.000215
ORF1ab/nsp3393V393FGttTtt22AY.50.000041
ORF1ab/nsp3393V393FGttTtt22AY.7.10.000225
ORF1ab/nsp3393V393FGttTtt22AY.9.10.000167
ORF1ab/nsp3393V393FGttTtt22AY.980.000158
ORF1ab/nsp3393V393FGttTtt22AY.99.20.000184
ORF1ab/nsp3393V393FGttTtt22B.1.1.1890.003026
ORF1ab/nsp3393V393FGttTtt22B.1.1.2140.000111
ORF1ab/nsp3393V393FGttTtt22B.1.1.2160.001781
ORF1ab/nsp3393V393FGttTtt22B.1.1.3060.000877
ORF1ab/nsp3393V393FGttTtt22B.1.1.3170.000823
ORF1ab/nsp3393V393FGttTtt22B.1.1.3180.000604
ORF1ab/nsp3393V393FGttTtt22B.1.1.5190.000079
ORF1ab/nsp3393V393FGttTtt22B.1.1.700.000682
ORF1ab/nsp3393V393FGttTtt22B.1.1110.00235
ORF1ab/nsp3393V393FGttTtt22B.1.177.570.000562
ORF1ab/nsp3393V393FGttTtt22B.1.36.330.015152
ORF1ab/nsp3393V393FGttTtt22B.1.416.10.003125
ORF1ab/nsp3393V393FGttTtt22B.1.5400.019417
ORF1ab/nsp3393V393FGttTtt22P.1.70.000639
ORF1ab/nsp3393V393FGttTtt11A.20.000662
ORF1ab/nsp3393V393FGttTtt11A.2.20.001689
ORF1ab/nsp3393V393FGttTtt11A.2.50.000499
ORF1ab/nsp3393V393FGttTtt11AU.20.002421
ORF1ab/nsp3393V393FGttTtt11AY.10.000396
ORF1ab/nsp3393V393FGttTtt11AY.1050.000643
ORF1ab/nsp3393V393FGttTtt11AY.1080.001103
ORF1ab/nsp3393V393FGttTtt11AY.1100.000113
ORF1ab/nsp3393V393FGttTtt11AY.1180.000063
ORF1ab/nsp3393V393FGttTtt11AY.1190.000035
ORF1ab/nsp3393V393FGttTtt11AY.120.20.001285
ORF1ab/nsp3393V393FGttTtt11AY.1210.000135
ORF1ab/nsp3393V393FGttTtt11AY.130.000161
ORF1ab/nsp3393V393FGttTtt11AY.16.10.00047
ORF1ab/nsp3393V393FGttTtt11AY.240.000431
ORF1ab/nsp3393V393FGttTtt11AY.370.000316
ORF1ab/nsp3393V393FGttTtt11AY.46.20.000635
ORF1ab/nsp3393V393FGttTtt11AY.46.60.000072
ORF1ab/nsp3393V393FGttTtt11AY.5.30.000337
ORF1ab/nsp3393V393FGttTtt11AY.550.000917
ORF1ab/nsp3393V393FGttTtt11AY.580.000907
ORF1ab/nsp3393V393FGttTtt11AY.660.00107
ORF1ab/nsp3393V393FGttTtt11AY.690.000187
ORF1ab/nsp3393V393FGttTtt11AY.710.000475
ORF1ab/nsp3393V393FGttTtt11AY.9.20.000037
ORF1ab/nsp3393V393FGttTtt11B.1.1.10.000327
ORF1ab/nsp3393V393FGttTtt11B.1.1.1530.001095
ORF1ab/nsp3393V393FGttTtt11B.1.1.2410.00207
ORF1ab/nsp3393V393FGttTtt11B.1.1.610.008772
ORF1ab/nsp3393V393FGttTtt11B.1.1040.00369
ORF1ab/nsp3393V393FGttTtt11B.1.130.002375
ORF1ab/nsp3393V393FGttTtt11B.1.1450.052632
ORF1ab/nsp3393V393FGttTtt11B.1.160.160.000929
ORF1ab/nsp3393V393FGttTtt11B.1.160.280.002924
ORF1ab/nsp3393V393FGttTtt11B.1.177.250.014925
ORF1ab/nsp3393V393FGttTtt11B.1.177.750.001041
ORF1ab/nsp3393V393FGttTtt11B.1.2790.000514
ORF1ab/nsp3393V393FGttTtt11B.1.3110.000275
ORF1ab/nsp3393V393FGttTtt11B.1.3820.008929
ORF1ab/nsp3393V393FGttTtt11B.1.4270.00005
ORF1ab/nsp3393V393FGttTtt11B.1.4530.003236
ORF1ab/nsp3393V393FGttTtt11B.1.4560.003268
ORF1ab/nsp3393V393FGttTtt11B.1.5960.000087
ORF1ab/nsp3393V393FGttTtt11B.1.6090.000479
ORF1ab/nsp3393V393FGttTtt11B.1.617.10.000129
ORF1ab/nsp3393V393FGttTtt11B.200.023256
ORF1ab/nsp3393V393FGttTtt11C.370.000116
ORF1ab/nsp3393V393FGttTtt11D.30.005917
ORF1ab/nsp3393V393FGttTtt11Q.10.000126
ORF1ab/nsp3393V393FGttTtt11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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