CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = V238L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3238V238LV1056LnonsynGtgTtg756874990.9908833431-3433
ORF1ab/nsp3238V238LV1056LnonsynGtgCtg7568600.007928123431-3433
ORF1ab/nsp3238V238LV1056LnonsynGtGTtA756890.001189223431-3433

Details of the mutation V238L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3238V238LGtgTtg74997568All0.001434
ORF1ab/nsp3238V238LGtgCtg607568All0.000011
ORF1ab/nsp3238V238LGtGTtA97568All0.000002
ORF1ab/nsp3238V238LGtgTtg16511657AY.1030.010251
ORF1ab/nsp3238V238LGtgCtg61657AY.1030.000037
ORF1ab/nsp3238V238LGtgTtg13101310B.1.36.271
ORF1ab/nsp3238V238LGtgTtg727727B.1.360.106069
ORF1ab/nsp3238V238LGtgTtg542562AY.40.000844
ORF1ab/nsp3238V238LGtgCtg20562AY.40.000031
ORF1ab/nsp3238V238LGtgTtg549556B.1.1.70.000491
ORF1ab/nsp3238V238LGtgCtg7556B.1.1.70.000006
ORF1ab/nsp3238V238LGtgTtg244244AY.440.001485
ORF1ab/nsp3238V238LGtgTtg240241B.1.617.20.000904
ORF1ab/nsp3238V238LGtgCtg1241B.1.617.20.000004
ORF1ab/nsp3238V238LGtgTtg172181B.1.1.2940.217722
ORF1ab/nsp3238V238LGtGTtA9181B.1.1.2940.011392
ORF1ab/nsp3238V238LGtgTtg133133B.1.1770.001751
ORF1ab/nsp3238V238LGtgTtg120122AY.250.000722
ORF1ab/nsp3238V238LGtgCtg2122AY.250.000012
ORF1ab/nsp3238V238LGtgTtg108109B.10.000989
ORF1ab/nsp3238V238LGtgCtg1109B.10.000009
ORF1ab/nsp3238V238LGtgTtg8989P.1.170.014397
ORF1ab/nsp3238V238LGtgTtg8282AY.98.10.003971
ORF1ab/nsp3238V238LGtgTtg7474B.1.2580.004924
ORF1ab/nsp3238V238LGtgTtg6464AY.940.028331
ORF1ab/nsp3238V238LGtgTtg6464B.1.177.180.074246
ORF1ab/nsp3238V238LGtgTtg6061AY.430.000266
ORF1ab/nsp3238V238LGtgCtg161AY.430.000004
ORF1ab/nsp3238V238LGtgTtg5657B.1.10.001016
ORF1ab/nsp3238V238LGtgCtg157B.1.10.000018
ORF1ab/nsp3238V238LGtgTtg4849B.1.4290.001129
ORF1ab/nsp3238V238LGtgCtg149B.1.4290.000024
ORF1ab/nsp3238V238LGtgTtg4848AY.460.004996
ORF1ab/nsp3238V238LGtgTtg4747AY.920.013502
ORF1ab/nsp3238V238LGtgTtg4141B.1.36.220.049517
ORF1ab/nsp3238V238LGtgTtg4040AY.420.001609
ORF1ab/nsp3238V238LGtgTtg3839AY.1200.001413
ORF1ab/nsp3238V238LGtgCtg139AY.1200.000037
ORF1ab/nsp3238V238LGtgTtg3737P.10.000583
ORF1ab/nsp3238V238LGtgTtg3236AY.30.000318
ORF1ab/nsp3238V238LGtgCtg436AY.30.00004
ORF1ab/nsp3238V238LGtgTtg3333AY.4.50.003547
ORF1ab/nsp3238V238LGtgTtg2930B.1.20.000255
ORF1ab/nsp3238V238LGtgCtg130B.1.20.000009
ORF1ab/nsp3238V238LGtgTtg3030N.50.053004
ORF1ab/nsp3238V238LGtgTtg2929B.1.2410.023539
ORF1ab/nsp3238V238LGtgTtg2727B.1.5950.007046
ORF1ab/nsp3238V238LGtgTtg2626B.1.1.630.010031
ORF1ab/nsp3238V238LGtgTtg2525AY.350.005826
ORF1ab/nsp3238V238LGtgTtg2323AY.470.000715
ORF1ab/nsp3238V238LGtgTtg2121AY.200.000816
ORF1ab/nsp3238V238LGtgTtg2121AY.4.20.000455
ORF1ab/nsp3238V238LGtgTtg2121B.1.2430.001461
ORF1ab/nsp3238V238LGtgTtg2020B.1.1.2030.338983
ORF1ab/nsp3238V238LGtgTtg1919AY.1060.006363
ORF1ab/nsp3238V238LGtgTtg1717AY.1020.000451
ORF1ab/nsp3238V238LGtgTtg1717B.1.1.5190.000675
ORF1ab/nsp3238V238LGtgTtg1717B.1.6210.001505
ORF1ab/nsp3238V238LGtgTtg1616B.1.1.2410.033126
ORF1ab/nsp3238V238LGtgTtg1414B.1.5260.000329
ORF1ab/nsp3238V238LGtgTtg1313B.1.3990.025145
ORF1ab/nsp3238V238LGtgTtg1212AY.390.000297
ORF1ab/nsp3238V238LGtgTtg1212B.1.4270.000606
ORF1ab/nsp3238V238LGtgTtg1111AY.50.000227
ORF1ab/nsp3238V238LGtgTtg1111AY.740.001272
ORF1ab/nsp3238V238LGtgTtg1010AY.750.00056
ORF1ab/nsp3238V238LGtgTtg99AY.1190.000318
ORF1ab/nsp3238V238LGtgTtg99B.1.1.5260.031915
ORF1ab/nsp3238V238LGtgTtg99B.1.3510.000268
ORF1ab/nsp3238V238LGtgTtg88AY.330.000534
ORF1ab/nsp3238V238LGtgTtg88AY.730.005323
ORF1ab/nsp3238V238LGtgTtg88B.1.1600.00025
ORF1ab/nsp3238V238LGtgTtg88B.1.2210.000568
ORF1ab/nsp3238V238LGtgTtg88B.1.2600.026756
ORF1ab/nsp3238V238LGtgTtg77AY.1000.000322
ORF1ab/nsp3238V238LGtgTtg77AY.260.000198
ORF1ab/nsp3238V238LGtgCtg77B.1.177.240.009067
ORF1ab/nsp3238V238LGtgTtg77C.370.000812
ORF1ab/nsp3238V238LGtgTtg77P.1.140.000335
ORF1ab/nsp3238V238LGtgTtg77P.1.70.002235
ORF1ab/nsp3238V238LGtgTtg66B.1.4680.034286
ORF1ab/nsp3238V238LGtgTtg55A.23.10.003521
ORF1ab/nsp3238V238LGtgTtg55AY.230.000349
ORF1ab/nsp3238V238LGtgTtg55AY.450.000608
ORF1ab/nsp3238V238LGtgTtg55B.1.1.2160.004452
ORF1ab/nsp3238V238LGtgTtg44AY.1210.000541
ORF1ab/nsp3238V238LGtgTtg44AY.160.001519
ORF1ab/nsp3238V238LGtgTtg44AY.20.001425
ORF1ab/nsp3238V238LGtgTtg44AY.270.000259
ORF1ab/nsp3238V238LGtgTtg44AY.60.000165
ORF1ab/nsp3238V238LGtgTtg24B0.000256
ORF1ab/nsp3238V238LGtgCtg24B0.000256
ORF1ab/nsp3238V238LGtgTtg44B.1.2360.008214
ORF1ab/nsp3238V238LGtgTtg44B.1.36.10.004561
ORF1ab/nsp3238V238LGtgTtg44B.1.36.160.005698
ORF1ab/nsp3238V238LGtgTtg44B.1.4560.013072
ORF1ab/nsp3238V238LGtgTtg44B.1.617.10.000516
ORF1ab/nsp3238V238LGtgTtg44Q.80.00066
ORF1ab/nsp3238V238LGtgTtg23AY.140.000176
ORF1ab/nsp3238V238LGtgCtg13AY.140.000088
ORF1ab/nsp3238V238LGtgTtg33AY.16.10.00141
ORF1ab/nsp3238V238LGtgTtg33AY.290.000047
ORF1ab/nsp3238V238LGtgTtg33AY.3.10.000256
ORF1ab/nsp3238V238LGtgTtg33AY.300.001187
ORF1ab/nsp3238V238LGtgTtg33AY.340.000291
ORF1ab/nsp3238V238LGtgTtg33AY.39.10.000119
ORF1ab/nsp3238V238LGtgTtg33AY.46.20.001906
ORF1ab/nsp3238V238LGtgTtg33AY.46.60.000217
ORF1ab/nsp3238V238LGtgTtg33AY.90.000203
ORF1ab/nsp3238V238LGtgTtg33B.1.1.280.000934
ORF1ab/nsp3238V238LGtgTtg33B.1.1.500.002037
ORF1ab/nsp3238V238LGtgTtg33B.1.177.650.001996
ORF1ab/nsp3238V238LGtgCtg33B.1.3110.000824
ORF1ab/nsp3238V238LGtgTtg33B.1.36.170.001482
ORF1ab/nsp3238V238LGtgTtg33B.1.36.380.004926
ORF1ab/nsp3238V238LGtgTtg33B.1.3610.003866
ORF1ab/nsp3238V238LGtgTtg33B.1.3960.002117
ORF1ab/nsp3238V238LGtgTtg33B.1.5250.000339
ORF1ab/nsp3238V238LGtgTtg33B.1.619.10.001924
ORF1ab/nsp3238V238LGtgTtg33B.1.6330.125
ORF1ab/nsp3238V238LGtgTtg33Q.10.000379
ORF1ab/nsp3238V238LGtgTtg22AY.1110.000366
ORF1ab/nsp3238V238LGtgTtg22AY.1170.000169
ORF1ab/nsp3238V238LGtgTtg22AY.190.002281
ORF1ab/nsp3238V238LGtgTtg22AY.370.000632
ORF1ab/nsp3238V238LGtgTtg22AY.610.00021
ORF1ab/nsp3238V238LGtgTtg22AY.680.000547
ORF1ab/nsp3238V238LGtgTtg22AY.75.10.000361
ORF1ab/nsp3238V238LGtgTtg22AY.80.001212
ORF1ab/nsp3238V238LGtgTtg22AY.9.20.000073
ORF1ab/nsp3238V238LGtgTtg22AY.980.000158
ORF1ab/nsp3238V238LGtgTtg22B.1.1.1100.181818
ORF1ab/nsp3238V238LGtgTtg22B.1.1.2200.003717
ORF1ab/nsp3238V238LGtgTtg22B.1.1.2220.000408
ORF1ab/nsp3238V238LGtgTtg22B.1.1.3480.001592
ORF1ab/nsp3238V238LGtgTtg22B.1.1.390.001019
ORF1ab/nsp3238V238LGtgTtg22B.1.1.4160.00181
ORF1ab/nsp3238V238LGtgTtg22B.1.1.4340.000697
ORF1ab/nsp3238V238LGtgTtg22B.1.1.890.012121
ORF1ab/nsp3238V238LGtgTtg22B.1.1110.00235
ORF1ab/nsp3238V238LGtgTtg22B.1.1390.001466
ORF1ab/nsp3238V238LGtgTtg22B.1.1470.001512
ORF1ab/nsp3238V238LGtgTtg22B.1.177.210.000153
ORF1ab/nsp3238V238LGtgTtg22B.1.177.320.002699
ORF1ab/nsp3238V238LGtgTtg22B.1.177.750.002081
ORF1ab/nsp3238V238LGtgTtg22B.1.2010.011364
ORF1ab/nsp3238V238LGtgTtg22B.1.3200.002491
ORF1ab/nsp3238V238LGtgTtg22B.1.36.290.001035
ORF1ab/nsp3238V238LGtgTtg22B.1.36.80.002
ORF1ab/nsp3238V238LGtgTtg22B.1.3750.001639
ORF1ab/nsp3238V238LGtgTtg22B.1.3830.018018
ORF1ab/nsp3238V238LGtgTtg22B.1.4450.023529
ORF1ab/nsp3238V238LGtgTtg22B.1.4620.014493
ORF1ab/nsp3238V238LGtgTtg22B.1.466.10.014388
ORF1ab/nsp3238V238LGtgTtg22B.1.4990.002101
ORF1ab/nsp3238V238LGtgTtg22B.1.5090.001732
ORF1ab/nsp3238V238LGtgTtg22B.1.6230.001073
ORF1ab/nsp3238V238LGtgTtg22C.360.001821
ORF1ab/nsp3238V238LGtgTtg22C.36.30.001134
ORF1ab/nsp3238V238LGtgTtg22D.20.00015
ORF1ab/nsp3238V238LGtgTtg22P.1.150.000465
ORF1ab/nsp3238V238LGtgTtg22Q.40.00091
ORF1ab/nsp3238V238LGtgTtg11A.2.20.001689
ORF1ab/nsp3238V238LGtgTtg11A.2.30.004739
ORF1ab/nsp3238V238LGtgTtg11A.2.50.000499
ORF1ab/nsp3238V238LGtgTtg11A.2.5.30.010309
ORF1ab/nsp3238V238LGtgTtg11AU.20.002421
ORF1ab/nsp3238V238LGtgTtg11AY.1050.000643
ORF1ab/nsp3238V238LGtgTtg11AY.1080.001103
ORF1ab/nsp3238V238LGtgTtg11AY.1090.00074
ORF1ab/nsp3238V238LGtgTtg11AY.1100.000113
ORF1ab/nsp3238V238LGtgTtg11AY.1180.000063
ORF1ab/nsp3238V238LGtgTtg11AY.120.2.10.000498
ORF1ab/nsp3238V238LGtgTtg11AY.130.000161
ORF1ab/nsp3238V238LGtgTtg11AY.210.001898
ORF1ab/nsp3238V238LGtgTtg11AY.23.10.000417
ORF1ab/nsp3238V238LGtgTtg11AY.320.000532
ORF1ab/nsp3238V238LGtgTtg11AY.46.40.000165
ORF1ab/nsp3238V238LGtgTtg11AY.46.50.000198
ORF1ab/nsp3238V238LGtgTtg11AY.5.40.000277
ORF1ab/nsp3238V238LGtgTtg11AY.570.000656
ORF1ab/nsp3238V238LGtgTtg11AY.590.00053
ORF1ab/nsp3238V238LGtgTtg11AY.600.000938
ORF1ab/nsp3238V238LGtgTtg11AY.670.000464
ORF1ab/nsp3238V238LGtgTtg11AY.700.000209
ORF1ab/nsp3238V238LGtgTtg11AY.840.000437
ORF1ab/nsp3238V238LGtgTtg11AY.850.000427
ORF1ab/nsp3238V238LGtgTtg11AY.860.00083
ORF1ab/nsp3238V238LGtgTtg11AY.890.004902
ORF1ab/nsp3238V238LGtgTtg11AY.910.00073
ORF1ab/nsp3238V238LGtgTtg11AY.99.20.000092
ORF1ab/nsp3238V238LGtgTtg11B.1.1.10.000327
ORF1ab/nsp3238V238LGtgTtg11B.1.1.1390.022727
ORF1ab/nsp3238V238LGtgTtg11B.1.1.1890.001513
ORF1ab/nsp3238V238LGtgTtg11B.1.1.1940.00495
ORF1ab/nsp3238V238LGtgTtg11B.1.1.2140.000055
ORF1ab/nsp3238V238LGtgTtg11B.1.1.250.000569
ORF1ab/nsp3238V238LGtgTtg11B.1.1.2910.000742
ORF1ab/nsp3238V238LGtgTtg11B.1.1.3060.000438
ORF1ab/nsp3238V238LGtgTtg11B.1.1.3180.000302
ORF1ab/nsp3238V238LGtgTtg11B.1.1.3260.001761
ORF1ab/nsp3238V238LGtgTtg11B.1.1.330.000421
ORF1ab/nsp3238V238LGtgTtg11B.1.1.3440.010753
ORF1ab/nsp3238V238LGtgTtg11B.1.1.370.000193
ORF1ab/nsp3238V238LGtgTtg11B.1.1260.001276
ORF1ab/nsp3238V238LGtgTtg11B.1.1640.014925
ORF1ab/nsp3238V238LGtgTtg11B.1.1700.00431
ORF1ab/nsp3238V238LGtgTtg11B.1.177.160.000664
ORF1ab/nsp3238V238LGtgTtg11B.1.177.190.001431
ORF1ab/nsp3238V238LGtgTtg11B.1.177.310.011494
ORF1ab/nsp3238V238LGtgTtg11B.1.177.40.000211
ORF1ab/nsp3238V238LGtgTtg11B.1.177.720.00339
ORF1ab/nsp3238V238LGtgTtg11B.1.177.860.000183
ORF1ab/nsp3238V238LGtgTtg11B.1.177.90.001332
ORF1ab/nsp3238V238LGtgTtg11B.1.2150.009615
ORF1ab/nsp3238V238LGtgTtg11B.1.2330.014085
ORF1ab/nsp3238V238LGtgTtg11B.1.2340.000132
ORF1ab/nsp3238V238LGtgTtg11B.1.258.110.000396
ORF1ab/nsp3238V238LGtgTtg11B.1.258.140.00098
ORF1ab/nsp3238V238LGtgTtg11B.1.2790.000514
ORF1ab/nsp3238V238LGtgTtg11B.1.30.002618
ORF1ab/nsp3238V238LGtgTtg11B.1.3560.001727
ORF1ab/nsp3238V238LGtgTtg11B.1.36.100.004785
ORF1ab/nsp3238V238LGtgTtg11B.1.36.330.007576
ORF1ab/nsp3238V238LGtgTtg11B.1.36.340.021277
ORF1ab/nsp3238V238LGtgTtg11B.1.36.390.002217
ORF1ab/nsp3238V238LGtgTtg11B.1.36.70.004
ORF1ab/nsp3238V238LGtgTtg11B.1.3670.000792
ORF1ab/nsp3238V238LGtgTtg11B.1.3690.000285
ORF1ab/nsp3238V238LGtgTtg11B.1.3970.004854
ORF1ab/nsp3238V238LGtgTtg11B.1.3980.002976
ORF1ab/nsp3238V238LGtgTtg11B.1.4000.000429
ORF1ab/nsp3238V238LGtgTtg11B.1.4160.001269
ORF1ab/nsp3238V238LGtgTtg11B.1.416.10.001563
ORF1ab/nsp3238V238LGtgTtg11B.1.4330.003195
ORF1ab/nsp3238V238LGtgTtg11B.1.5230.002451
ORF1ab/nsp3238V238LGtgTtg11B.1.5330.009615
ORF1ab/nsp3238V238LGtgTtg11B.1.5400.009709
ORF1ab/nsp3238V238LGtgTtg11B.1.5850.027778
ORF1ab/nsp3238V238LGtgTtg11B.1.5900.004545
ORF1ab/nsp3238V238LGtgTtg11B.1.5960.000087
ORF1ab/nsp3238V238LGtgTtg11B.1.6010.030303
ORF1ab/nsp3238V238LGtgCtg11B.1.6090.000479
ORF1ab/nsp3238V238LGtgTtg11B.1.6280.000352
ORF1ab/nsp3238V238LGtgTtg11B.1.6320.006711
ORF1ab/nsp3238V238LGtgTtg11B.1.780.008547
ORF1ab/nsp3238V238LGtgTtg11B.460.020833
ORF1ab/nsp3238V238LGtgTtg11C.170.055556
ORF1ab/nsp3238V238LGtgTtg11C.37.10.002618
ORF1ab/nsp3238V238LGtgTtg11N.40.004255
ORF1ab/nsp3238V238LGtgTtg11N.90.005952
ORF1ab/nsp3238V238LGtgTtg11P.1.60.001946
ORF1ab/nsp3238V238LGtgTtg11P.70.004367
ORF1ab/nsp3238V238LGtgTtg11W.40.001351

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.