CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = V1580V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31580V1580VV2398VsyngtGgtT6924680.6763017457-7459
ORF1ab/nsp31580V1580VV2398VsyngtGgtA6922200.3179197457-7459
ORF1ab/nsp31580V1580VV2398VsyngtGgtC69240.005780357457-7459

Details of the mutation V1580V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31580V1580VgtGgtT468692All0.00009
ORF1ab/nsp31580V1580VgtGgtA220692All0.000042
ORF1ab/nsp31580V1580VgtGgtC4692All0.000001
ORF1ab/nsp31580V1580VgtGgtA137151B.1.1.70.000123
ORF1ab/nsp31580V1580VgtGgtT13151B.1.1.70.000012
ORF1ab/nsp31580V1580VgtGgtC1151B.1.1.70.000001
ORF1ab/nsp31580V1580VgtGgtT135135B.1.9.40.828221
ORF1ab/nsp31580V1580VgtGgtT111118B.10.001017
ORF1ab/nsp31580V1580VgtGgtA5118B.10.000046
ORF1ab/nsp31580V1580VgtGgtC2118B.10.000018
ORF1ab/nsp31580V1580VgtGgtT4242AY.4.20.000911
ORF1ab/nsp31580V1580VgtGgtT2932AY.40.000045
ORF1ab/nsp31580V1580VgtGgtA332AY.40.000005
ORF1ab/nsp31580V1580VgtGgtT2728B.1.20.000238
ORF1ab/nsp31580V1580VgtGgtA128B.1.20.000009
ORF1ab/nsp31580V1580VgtGgtT1414AY.39.10.000555
ORF1ab/nsp31580V1580VgtGgtT713AY.250.000042
ORF1ab/nsp31580V1580VgtGgtA613AY.250.000036
ORF1ab/nsp31580V1580VgtGgtA1111AY.46.40.00181
ORF1ab/nsp31580V1580VgtGgtT89B.1.617.20.00003
ORF1ab/nsp31580V1580VgtGgtA19B.1.617.20.000004
ORF1ab/nsp31580V1580VgtGgtT88AY.430.000035
ORF1ab/nsp31580V1580VgtGgtT88P.20.001493
ORF1ab/nsp31580V1580VgtGgtT77B.1.90.04321
ORF1ab/nsp31580V1580VgtGgtT46B0.000511
ORF1ab/nsp31580V1580VgtGgtA26B0.000256
ORF1ab/nsp31580V1580VgtGgtT66B.1.1260.007653
ORF1ab/nsp31580V1580VgtGgtA56P.10.000079
ORF1ab/nsp31580V1580VgtGgtT16P.10.000016
ORF1ab/nsp31580V1580VgtGgtA55AY.230.000349
ORF1ab/nsp31580V1580VgtGgtA35B.1.10.000054
ORF1ab/nsp31580V1580VgtGgtT25B.1.10.000036
ORF1ab/nsp31580V1580VgtGgtA55Q.80.000825
ORF1ab/nsp31580V1580VgtGgtT34AY.440.000018
ORF1ab/nsp31580V1580VgtGgtA14AY.440.000006
ORF1ab/nsp31580V1580VgtGgtA44AY.470.000124
ORF1ab/nsp31580V1580VgtGgtT44B.1.4250.011976
ORF1ab/nsp31580V1580VgtGgtA44B.1.4290.000094
ORF1ab/nsp31580V1580VgtGgtT44B.1.6210.000354
ORF1ab/nsp31580V1580VgtGgtA33AY.450.000365
ORF1ab/nsp31580V1580VgtGgtA33B.1.1.250.001706
ORF1ab/nsp31580V1580VgtGgtA33B.1.3510.000089
ORF1ab/nsp31580V1580VgtGgtT33B.1.9.50.017045
ORF1ab/nsp31580V1580VgtGgtA12AY.1000.000046
ORF1ab/nsp31580V1580VgtGgtT12AY.1000.000046
ORF1ab/nsp31580V1580VgtGgtT22AY.290.000032
ORF1ab/nsp31580V1580VgtGgtT22B.1.1.2840.000215
ORF1ab/nsp31580V1580VgtGgtA12B.1.1770.000013
ORF1ab/nsp31580V1580VgtGgtT12B.1.1770.000013
ORF1ab/nsp31580V1580VgtGgtT22B.1.177.860.000367
ORF1ab/nsp31580V1580VgtGgtT12B.1.2210.000071
ORF1ab/nsp31580V1580VgtGgtA12B.1.2210.000071
ORF1ab/nsp31580V1580VgtGgtT22B.1.2340.000264
ORF1ab/nsp31580V1580VgtGgtA22B.1.351.30.001753
ORF1ab/nsp31580V1580VgtGgtA22B.1.5750.000607
ORF1ab/nsp31580V1580VgtGgtC12C.370.000116
ORF1ab/nsp31580V1580VgtGgtT12C.370.000116
ORF1ab/nsp31580V1580VgtGgtA11AY.1030.000006
ORF1ab/nsp31580V1580VgtGgtA11AY.1090.00074
ORF1ab/nsp31580V1580VgtGgtT11AY.1200.000037
ORF1ab/nsp31580V1580VgtGgtT11AY.16.10.00047
ORF1ab/nsp31580V1580VgtGgtT11AY.23.10.000417
ORF1ab/nsp31580V1580VgtGgtT11AY.260.000028
ORF1ab/nsp31580V1580VgtGgtA11AY.30.00001
ORF1ab/nsp31580V1580VgtGgtT11AY.330.000067
ORF1ab/nsp31580V1580VgtGgtA11AY.350.000233
ORF1ab/nsp31580V1580VgtGgtT11AY.4.2.10.000149
ORF1ab/nsp31580V1580VgtGgtT11AY.50.000021
ORF1ab/nsp31580V1580VgtGgtT11AY.90.000068
ORF1ab/nsp31580V1580VgtGgtT11AY.980.000079
ORF1ab/nsp31580V1580VgtGgtT11B.1.1.10.000327
ORF1ab/nsp31580V1580VgtGgtT11B.1.1.1890.001513
ORF1ab/nsp31580V1580VgtGgtT11B.1.1.2740.005051
ORF1ab/nsp31580V1580VgtGgtT11B.1.1.4340.000349
ORF1ab/nsp31580V1580VgtGgtT11B.1.1.5190.00004
ORF1ab/nsp31580V1580VgtGgtA11B.1.1600.000031
ORF1ab/nsp31580V1580VgtGgtT11B.1.177.730.000566
ORF1ab/nsp31580V1580VgtGgtT11B.1.2320.000537
ORF1ab/nsp31580V1580VgtGgtT11B.1.2580.000067
ORF1ab/nsp31580V1580VgtGgtT11B.1.3240.001605
ORF1ab/nsp31580V1580VgtGgtA11B.1.360.000146
ORF1ab/nsp31580V1580VgtGgtA11B.1.36.100.004785
ORF1ab/nsp31580V1580VgtGgtA11B.1.3610.001289
ORF1ab/nsp31580V1580VgtGgtA11B.1.4660.023256
ORF1ab/nsp31580V1580VgtGgtT11B.1.4990.00105
ORF1ab/nsp31580V1580VgtGgtA11B.1.5260.000024
ORF1ab/nsp31580V1580VgtGgtA11B.1.6200.000946
ORF1ab/nsp31580V1580VgtGgtT11B.1.6270.00202

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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