CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = V1522V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31522V1522VV2340VsyngtAgtG1691510.8934917283-7285
ORF1ab/nsp31522V1522VV2340VsyngtAgtT169120.07100597283-7285
ORF1ab/nsp31522V1522VV2340VsyngtAgtC16960.0355037283-7285

Details of the mutation V1522V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31522V1522VgtAgtG151169All0.000029
ORF1ab/nsp31522V1522VgtAgtT12169All0.000002
ORF1ab/nsp31522V1522VgtAgtC6169All0.000001
ORF1ab/nsp31522V1522VgtAgtG2727AY.40.000042
ORF1ab/nsp31522V1522VgtAgtG2023B.1.617.20.000075
ORF1ab/nsp31522V1522VgtAgtC223B.1.617.20.000008
ORF1ab/nsp31522V1522VgtAgtT123B.1.617.20.000004
ORF1ab/nsp31522V1522VgtAgtG1719B.1.1.70.000015
ORF1ab/nsp31522V1522VgtAgtT219B.1.1.70.000002
ORF1ab/nsp31522V1522VgtAgtG1313AY.250.000078
ORF1ab/nsp31522V1522VgtAgtG811B.1.10.000145
ORF1ab/nsp31522V1522VgtAgtT311B.1.10.000054
ORF1ab/nsp31522V1522VgtAgtG88AY.430.000035
ORF1ab/nsp31522V1522VgtAgtG88B.1.438.10.000858
ORF1ab/nsp31522V1522VgtAgtG44AY.1030.000025
ORF1ab/nsp31522V1522VgtAgtG44AY.470.000124
ORF1ab/nsp31522V1522VgtAgtG34B.10.000027
ORF1ab/nsp31522V1522VgtAgtT14B.10.000009
ORF1ab/nsp31522V1522VgtAgtG23AY.1020.000053
ORF1ab/nsp31522V1522VgtAgtT13AY.1020.000027
ORF1ab/nsp31522V1522VgtAgtG33AY.30.00003
ORF1ab/nsp31522V1522VgtAgtG33AY.4.20.000065
ORF1ab/nsp31522V1522VgtAgtG33AY.440.000018
ORF1ab/nsp31522V1522VgtAgtG33B.1.1770.00004
ORF1ab/nsp31522V1522VgtAgtG33B.1.6370.000219
ORF1ab/nsp31522V1522VgtAgtT220.111111
ORF1ab/nsp31522V1522VgtAgtG22B.1.214.20.001199
ORF1ab/nsp31522V1522VgtAgtG22B.1.5260.000047
ORF1ab/nsp31522V1522VgtAgtG11A0.000387
ORF1ab/nsp31522V1522VgtAgtG11AY.1000.000046
ORF1ab/nsp31522V1522VgtAgtG11AY.1090.00074
ORF1ab/nsp31522V1522VgtAgtG11AY.1170.000085
ORF1ab/nsp31522V1522VgtAgtG11AY.230.00007
ORF1ab/nsp31522V1522VgtAgtG11AY.290.000016
ORF1ab/nsp31522V1522VgtAgtC11AY.390.000025
ORF1ab/nsp31522V1522VgtAgtG11AY.410.000294
ORF1ab/nsp31522V1522VgtAgtT11AY.690.000187
ORF1ab/nsp31522V1522VgtAgtG11AY.740.000116
ORF1ab/nsp31522V1522VgtAgtC11B.1.1.330.000421
ORF1ab/nsp31522V1522VgtAgtG11B.1.1.5190.00004
ORF1ab/nsp31522V1522VgtAgtC11B.1.1240.007812
ORF1ab/nsp31522V1522VgtAgtG11B.1.177.160.000664
ORF1ab/nsp31522V1522VgtAgtG11B.1.20.000009
ORF1ab/nsp31522V1522VgtAgtG11B.1.2210.000071
ORF1ab/nsp31522V1522VgtAgtG11B.1.2650.001271
ORF1ab/nsp31522V1522VgtAgtG11B.1.3510.00003
ORF1ab/nsp31522V1522VgtAgtG11B.1.3990.001934
ORF1ab/nsp31522V1522VgtAgtG11B.1.4000.000429
ORF1ab/nsp31522V1522VgtAgtT11B.1.617.10.000129
ORF1ab/nsp31522V1522VgtAgtG11B.1.6270.00202
ORF1ab/nsp31522V1522VgtAgtC11C.350.000774
ORF1ab/nsp31522V1522VgtAgtG11P.10.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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