CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = V1388V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31388V1388VV2206VsyngtCgtT550054410.9892736881-6883
ORF1ab/nsp31388V1388VV2206VsyngtCgtA5500560.01018186881-6883
ORF1ab/nsp31388V1388VV2206VsyngtCgtG550030.0005454556881-6883

Details of the mutation V1388V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31388V1388VgtCgtT54415500All0.001041
ORF1ab/nsp31388V1388VgtCgtA565500All0.000011
ORF1ab/nsp31388V1388VgtCgtG35500All0.000001
ORF1ab/nsp31388V1388VgtCgtT17751776AY.390.043863
ORF1ab/nsp31388V1388VgtCgtA11776AY.390.000025
ORF1ab/nsp31388V1388VgtCgtT718718B.1.1.2940.908861
ORF1ab/nsp31388V1388VgtCgtT643643AY.39.20.990755
ORF1ab/nsp31388V1388VgtCgtT481481B.1.1.70.000431
ORF1ab/nsp31388V1388VgtCgtT246247AY.1030.001527
ORF1ab/nsp31388V1388VgtCgtA1247AY.1030.000006
ORF1ab/nsp31388V1388VgtCgtT168168AY.46.60.012131
ORF1ab/nsp31388V1388VgtCgtT148154B.1.20.001303
ORF1ab/nsp31388V1388VgtCgtA6154B.1.20.000053
ORF1ab/nsp31388V1388VgtCgtT149150B.1.617.20.000561
ORF1ab/nsp31388V1388VgtCgtA1150B.1.617.20.000004
ORF1ab/nsp31388V1388VgtCgtT122122B.1.5260.002868
ORF1ab/nsp31388V1388VgtCgtT9193AY.40.000142
ORF1ab/nsp31388V1388VgtCgtA293AY.40.000003
ORF1ab/nsp31388V1388VgtCgtT6263AY.430.000275
ORF1ab/nsp31388V1388VgtCgtA163AY.430.000004
ORF1ab/nsp31388V1388VgtCgtT5354B.1.10.000961
ORF1ab/nsp31388V1388VgtCgtA154B.1.10.000018
ORF1ab/nsp31388V1388VgtCgtT5252B.1.3630.675325
ORF1ab/nsp31388V1388VgtCgtT4242AY.250.000253
ORF1ab/nsp31388V1388VgtCgtT4242M.10.976744
ORF1ab/nsp31388V1388VgtCgtT3436B.10.000311
ORF1ab/nsp31388V1388VgtCgtA236B.10.000018
ORF1ab/nsp31388V1388VgtCgtT3535P.10.000551
ORF1ab/nsp31388V1388VgtCgtT2831AY.30.000278
ORF1ab/nsp31388V1388VgtCgtG231AY.30.00002
ORF1ab/nsp31388V1388VgtCgtA131AY.30.00001
ORF1ab/nsp31388V1388VgtCgtT3031AY.440.000183
ORF1ab/nsp31388V1388VgtCgtA131AY.440.000006
ORF1ab/nsp31388V1388VgtCgtT2828AY.39.10.001109
ORF1ab/nsp31388V1388VgtCgtT2024AY.1210.002706
ORF1ab/nsp31388V1388VgtCgtA424AY.1210.000541
ORF1ab/nsp31388V1388VgtCgtT1324AY.9.20.000477
ORF1ab/nsp31388V1388VgtCgtA1124AY.9.20.000404
ORF1ab/nsp31388V1388VgtCgtT2323AY.200.000894
ORF1ab/nsp31388V1388VgtCgtT1818Q.20.011043
ORF1ab/nsp31388V1388VgtCgtT1516AY.1020.000398
ORF1ab/nsp31388V1388VgtCgtA116AY.1020.000027
ORF1ab/nsp31388V1388VgtCgtT1616B.1.6350.280702
ORF1ab/nsp31388V1388VgtCgtT1415AY.260.000396
ORF1ab/nsp31388V1388VgtCgtA115AY.260.000028
ORF1ab/nsp31388V1388VgtCgtT1213B.1.3510.000357
ORF1ab/nsp31388V1388VgtCgtA113B.1.3510.00003
ORF1ab/nsp31388V1388VgtCgtT1313M.31
ORF1ab/nsp31388V1388VgtCgtA812B.1.4290.000188
ORF1ab/nsp31388V1388VgtCgtT412B.1.4290.000094
ORF1ab/nsp31388V1388VgtCgtT1111AY.1000.000506
ORF1ab/nsp31388V1388VgtCgtT1011B.1.1770.000132
ORF1ab/nsp31388V1388VgtCgtA111B.1.1770.000013
ORF1ab/nsp31388V1388VgtCgtT89AY.3.10.000682
ORF1ab/nsp31388V1388VgtCgtA19AY.3.10.000085
ORF1ab/nsp31388V1388VgtCgtT99B.1.177.510.041096
ORF1ab/nsp31388V1388VgtCgtT99M.20.75
ORF1ab/nsp31388V1388VgtCgtT88AY.1190.000282
ORF1ab/nsp31388V1388VgtCgtT88AY.610.000838
ORF1ab/nsp31388V1388VgtCgtT88B.1.1260.010204
ORF1ab/nsp31388V1388VgtCgtT88P.1.100.002156
ORF1ab/nsp31388V1388VgtCgtT77AY.4.20.000152
ORF1ab/nsp31388V1388VgtCgtT67B.1.1.5190.000238
ORF1ab/nsp31388V1388VgtCgtA17B.1.1.5190.00004
ORF1ab/nsp31388V1388VgtCgtT66B.1.1.280.001867
ORF1ab/nsp31388V1388VgtCgtT66B.1.1.3050.023166
ORF1ab/nsp31388V1388VgtCgtT66B.1.177.110.010187
ORF1ab/nsp31388V1388VgtCgtT66B.1.2340.000792
ORF1ab/nsp31388V1388VgtCgtT66C.370.000696
ORF1ab/nsp31388V1388VgtCgtT55AY.1170.000423
ORF1ab/nsp31388V1388VgtCgtT55AY.230.000349
ORF1ab/nsp31388V1388VgtCgtT55AY.330.000334
ORF1ab/nsp31388V1388VgtCgtT55AY.460.00052
ORF1ab/nsp31388V1388VgtCgtT55AY.980.000395
ORF1ab/nsp31388V1388VgtCgtT55B.1.1.3060.002192
ORF1ab/nsp31388V1388VgtCgtT44AY.360.000593
ORF1ab/nsp31388V1388VgtCgtT44AY.420.000161
ORF1ab/nsp31388V1388VgtCgtT34AY.9.10.000251
ORF1ab/nsp31388V1388VgtCgtG14AY.9.10.000084
ORF1ab/nsp31388V1388VgtCgtT44B.1.1.2320.00726
ORF1ab/nsp31388V1388VgtCgtT44B.1.177.810.000757
ORF1ab/nsp31388V1388VgtCgtT44B.1.5870.00759
ORF1ab/nsp31388V1388VgtCgtT44B.1.6370.000292
ORF1ab/nsp31388V1388VgtCgtT33AY.1100.000338
ORF1ab/nsp31388V1388VgtCgtT33AY.1180.000188
ORF1ab/nsp31388V1388VgtCgtT33AY.1200.000112
ORF1ab/nsp31388V1388VgtCgtT33AY.160.001139
ORF1ab/nsp31388V1388VgtCgtT33AY.270.000194
ORF1ab/nsp31388V1388VgtCgtT33AY.290.000047
ORF1ab/nsp31388V1388VgtCgtT33AY.4.2.10.000447
ORF1ab/nsp31388V1388VgtCgtT33AY.470.000093
ORF1ab/nsp31388V1388VgtCgtT33AY.50.000062
ORF1ab/nsp31388V1388VgtCgtT33AY.650.001599
ORF1ab/nsp31388V1388VgtCgtT33AY.75.10.000541
ORF1ab/nsp31388V1388VgtCgtT33AY.910.002191
ORF1ab/nsp31388V1388VgtCgtT23AY.99.20.000184
ORF1ab/nsp31388V1388VgtCgtA13AY.99.20.000092
ORF1ab/nsp31388V1388VgtCgtT33B.1.1.1610.010601
ORF1ab/nsp31388V1388VgtCgtT23B.1.1.2140.000111
ORF1ab/nsp31388V1388VgtCgtA13B.1.1.2140.000055
ORF1ab/nsp31388V1388VgtCgtT33B.1.1.2770.002276
ORF1ab/nsp31388V1388VgtCgtT33B.1.1.4160.002715
ORF1ab/nsp31388V1388VgtCgtT33B.1.2200.032609
ORF1ab/nsp31388V1388VgtCgtT33B.1.2580.0002
ORF1ab/nsp31388V1388VgtCgtT33B.1.36.220.003623
ORF1ab/nsp31388V1388VgtCgtA23P.1.170.000324
ORF1ab/nsp31388V1388VgtCgtT13P.1.170.000162
ORF1ab/nsp31388V1388VgtCgtT33P.20.00056
ORF1ab/nsp31388V1388VgtCgtT12A0.000387
ORF1ab/nsp31388V1388VgtCgtA12A0.000387
ORF1ab/nsp31388V1388VgtCgtT22AY.1110.000366
ORF1ab/nsp31388V1388VgtCgtT22AY.1130.000285
ORF1ab/nsp31388V1388VgtCgtT22AY.4.50.000215
ORF1ab/nsp31388V1388VgtCgtT22AY.5.40.000553
ORF1ab/nsp31388V1388VgtCgtT22AY.590.001059
ORF1ab/nsp31388V1388VgtCgtT22AY.60.000082
ORF1ab/nsp31388V1388VgtCgtT22AY.740.000231
ORF1ab/nsp31388V1388VgtCgtT22AY.840.000875
ORF1ab/nsp31388V1388VgtCgtT22B.1.1.100.00223
ORF1ab/nsp31388V1388VgtCgtT22B.1.1.1760.000879
ORF1ab/nsp31388V1388VgtCgtT22B.1.1.2890.004167
ORF1ab/nsp31388V1388VgtCgtT22B.1.1.3330.002153
ORF1ab/nsp31388V1388VgtCgtT22B.1.1.4340.000697
ORF1ab/nsp31388V1388VgtCgtT22B.1.1.4640.002946
ORF1ab/nsp31388V1388VgtCgtT22B.1.36.180.00084
ORF1ab/nsp31388V1388VgtCgtT22B.1.4270.000101
ORF1ab/nsp31388V1388VgtCgtT22B.1.4450.023529
ORF1ab/nsp31388V1388VgtCgtT22B.1.4970.00063
ORF1ab/nsp31388V1388VgtCgtT22B.1.5960.000174
ORF1ab/nsp31388V1388VgtCgtT22C.360.001821
ORF1ab/nsp31388V1388VgtCgtT22Q.80.00033
ORF1ab/nsp31388V1388VgtCgtT110.055556
ORF1ab/nsp31388V1388VgtCgtT11A.180.05
ORF1ab/nsp31388V1388VgtCgtT11A.2.50.000499
ORF1ab/nsp31388V1388VgtCgtT11AY.10.000396
ORF1ab/nsp31388V1388VgtCgtT11AY.1050.000643
ORF1ab/nsp31388V1388VgtCgtT11AY.1080.001103
ORF1ab/nsp31388V1388VgtCgtT11AY.110.001339
ORF1ab/nsp31388V1388VgtCgtT11AY.16.10.00047
ORF1ab/nsp31388V1388VgtCgtT11AY.20.000356
ORF1ab/nsp31388V1388VgtCgtT11AY.240.000431
ORF1ab/nsp31388V1388VgtCgtT11AY.320.000532
ORF1ab/nsp31388V1388VgtCgtT11AY.480.000465
ORF1ab/nsp31388V1388VgtCgtT11AY.550.000917
ORF1ab/nsp31388V1388VgtCgtT11AY.600.000938
ORF1ab/nsp31388V1388VgtCgtA11AY.70.000196
ORF1ab/nsp31388V1388VgtCgtT11AY.7.10.000113
ORF1ab/nsp31388V1388VgtCgtT11AY.750.000056
ORF1ab/nsp31388V1388VgtCgtT11AY.810.001992
ORF1ab/nsp31388V1388VgtCgtT11AY.880.000884
ORF1ab/nsp31388V1388VgtCgtT11AY.920.000287
ORF1ab/nsp31388V1388VgtCgtT11AY.990.001049
ORF1ab/nsp31388V1388VgtCgtT11AZ.10.000867
ORF1ab/nsp31388V1388VgtCgtT11B0.000128
ORF1ab/nsp31388V1388VgtCgtT11B.1.1.2840.000107
ORF1ab/nsp31388V1388VgtCgtT11B.1.1.3070.002532
ORF1ab/nsp31388V1388VgtCgtA11B.1.1.3160.000925
ORF1ab/nsp31388V1388VgtCgtT11B.1.1.330.000421
ORF1ab/nsp31388V1388VgtCgtT11B.1.1.3360.016667
ORF1ab/nsp31388V1388VgtCgtT11B.1.1.3760.005952
ORF1ab/nsp31388V1388VgtCgtT11B.1.1.4860.001577
ORF1ab/nsp31388V1388VgtCgtT11B.1.1.630.000386
ORF1ab/nsp31388V1388VgtCgtT11B.1.1040.00369
ORF1ab/nsp31388V1388VgtCgtT11B.1.1150.021739
ORF1ab/nsp31388V1388VgtCgtA11B.1.1280.000635
ORF1ab/nsp31388V1388VgtCgtT11B.1.1490.003425
ORF1ab/nsp31388V1388VgtCgtT11B.1.1600.000031
ORF1ab/nsp31388V1388VgtCgtT11B.1.177.210.000076
ORF1ab/nsp31388V1388VgtCgtA11B.1.177.320.00135
ORF1ab/nsp31388V1388VgtCgtT11B.1.177.350.000691
ORF1ab/nsp31388V1388VgtCgtT11B.1.177.570.000281
ORF1ab/nsp31388V1388VgtCgtT11B.1.177.650.000665
ORF1ab/nsp31388V1388VgtCgtT11B.1.177.70.000165
ORF1ab/nsp31388V1388VgtCgtT11B.1.2210.000071
ORF1ab/nsp31388V1388VgtCgtT11B.1.221.10.002907
ORF1ab/nsp31388V1388VgtCgtT11B.1.2430.00007
ORF1ab/nsp31388V1388VgtCgtT11B.1.258.170.000104
ORF1ab/nsp31388V1388VgtCgtT11B.1.36.280.005747
ORF1ab/nsp31388V1388VgtCgtA11B.1.3750.00082
ORF1ab/nsp31388V1388VgtCgtT11B.1.4040.001302
ORF1ab/nsp31388V1388VgtCgtT11B.1.4260.001009
ORF1ab/nsp31388V1388VgtCgtT11B.1.438.10.000107
ORF1ab/nsp31388V1388VgtCgtT11B.1.4480.002625
ORF1ab/nsp31388V1388VgtCgtT11B.1.4620.007246
ORF1ab/nsp31388V1388VgtCgtT11B.1.4680.005714
ORF1ab/nsp31388V1388VgtCgtT11B.1.4990.00105
ORF1ab/nsp31388V1388VgtCgtT11B.1.5250.000113
ORF1ab/nsp31388V1388VgtCgtT11B.1.5430.01
ORF1ab/nsp31388V1388VgtCgtT11B.1.5480.035714
ORF1ab/nsp31388V1388VgtCgtT11B.1.5510.00129
ORF1ab/nsp31388V1388VgtCgtT11B.1.5750.000303
ORF1ab/nsp31388V1388VgtCgtT11B.1.617.10.000129
ORF1ab/nsp31388V1388VgtCgtT11B.1.6210.000089
ORF1ab/nsp31388V1388VgtCgtT11B.1.621.10.000506
ORF1ab/nsp31388V1388VgtCgtT11D.20.000075
ORF1ab/nsp31388V1388VgtCgtT11N.50.001767
ORF1ab/nsp31388V1388VgtCgtT11P.1.150.000232
ORF1ab/nsp31388V1388VgtCgtT11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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