CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = T763M

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3763T763MT1581MnonsynaCgaTg1587158715006-5008

Details of the mutation T763M within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3763T763MaCgaTg15871587All0.000304
ORF1ab/nsp3763T763MaCgaTg665665B.1.1.4330.947293
ORF1ab/nsp3763T763MaCgaTg202202AY.420.008126
ORF1ab/nsp3763T763MaCgaTg181181B.1.1.70.000162
ORF1ab/nsp3763T763MaCgaTg110110AY.40.000171
ORF1ab/nsp3763T763MaCgaTg3434B.1.5960.002963
ORF1ab/nsp3763T763MaCgaTg2929B.1.617.20.000109
ORF1ab/nsp3763T763MaCgaTg2525B.10.000229
ORF1ab/nsp3763T763MaCgaTg2424B.1.20.000211
ORF1ab/nsp3763T763MaCgaTg2222AY.1030.000137
ORF1ab/nsp3763T763MaCgaTg1919AY.430.000084
ORF1ab/nsp3763T763MaCgaTg1616AY.440.000097
ORF1ab/nsp3763T763MaCgaTg1616B.1.10.00029
ORF1ab/nsp3763T763MaCgaTg1111AY.390.000272
ORF1ab/nsp3763T763MaCgaTg1111B.1.1.280.003424
ORF1ab/nsp3763T763MaCgaTg1111P.10.000173
ORF1ab/nsp3763T763MaCgaTg1010B0.001278
ORF1ab/nsp3763T763MaCgaTg1010B.1.4270.000505
ORF1ab/nsp3763T763MaCgaTg1010B.1.4290.000235
ORF1ab/nsp3763T763MaCgaTg1010B.1.6370.000731
ORF1ab/nsp3763T763MaCgaTg99AY.250.000054
ORF1ab/nsp3763T763MaCgaTg77B.1.1.2220.001428
ORF1ab/nsp3763T763MaCgaTg77B.1.3510.000208
ORF1ab/nsp3763T763MaCgaTg66AY.30.00006
ORF1ab/nsp3763T763MaCgaTg66AY.750.000336
ORF1ab/nsp3763T763MaCgaTg55AY.90.000338
ORF1ab/nsp3763T763MaCgaTg55B.1.1110.005875
ORF1ab/nsp3763T763MaCgaTg55B.1.2430.000348
ORF1ab/nsp3763T763MaCgaTg55B.1.5260.000118
ORF1ab/nsp3763T763MaCgaTg44AY.1000.000184
ORF1ab/nsp3763T763MaCgaTg44AY.1200.000149
ORF1ab/nsp3763T763MaCgaTg44AY.260.000113
ORF1ab/nsp3763T763MaCgaTg44B.1.1.3280.067797
ORF1ab/nsp3763T763MaCgaTg44B.1.1770.000053
ORF1ab/nsp3763T763MaCgaTg44B.1.4800.00995
ORF1ab/nsp3763T763MaCgaTg33AY.1180.000188
ORF1ab/nsp3763T763MaCgaTg33AY.270.000194
ORF1ab/nsp3763T763MaCgaTg33AY.75.10.000541
ORF1ab/nsp3763T763MaCgaTg33AY.9.10.000251
ORF1ab/nsp3763T763MaCgaTg22AY.4.20.000043
ORF1ab/nsp3763T763MaCgaTg22AY.450.000243
ORF1ab/nsp3763T763MaCgaTg22B.1.1.1410.004024
ORF1ab/nsp3763T763MaCgaTg22B.1.1.390.001019
ORF1ab/nsp3763T763MaCgaTg22B.1.1260.002551
ORF1ab/nsp3763T763MaCgaTg22B.1.177.120.000303
ORF1ab/nsp3763T763MaCgaTg22B.1.177.240.002591
ORF1ab/nsp3763T763MaCgaTg22B.1.177.80.001505
ORF1ab/nsp3763T763MaCgaTg22B.1.3960.001411
ORF1ab/nsp3763T763MaCgaTg22B.1.4160.002538
ORF1ab/nsp3763T763MaCgaTg22B.1.5870.003795
ORF1ab/nsp3763T763MaCgaTg22B.1.621.10.001012
ORF1ab/nsp3763T763MaCgaTg11A.30.002096
ORF1ab/nsp3763T763MaCgaTg11AY.1020.000027
ORF1ab/nsp3763T763MaCgaTg11AY.1130.000142
ORF1ab/nsp3763T763MaCgaTg11AY.1160.000287
ORF1ab/nsp3763T763MaCgaTg11AY.120.000316
ORF1ab/nsp3763T763MaCgaTg11AY.200.000039
ORF1ab/nsp3763T763MaCgaTg11AY.230.00007
ORF1ab/nsp3763T763MaCgaTg11AY.240.000431
ORF1ab/nsp3763T763MaCgaTg11AY.290.000016
ORF1ab/nsp3763T763MaCgaTg11AY.3.10.000085
ORF1ab/nsp3763T763MaCgaTg11AY.330.000067
ORF1ab/nsp3763T763MaCgaTg11AY.340.000097
ORF1ab/nsp3763T763MaCgaTg11AY.350.000233
ORF1ab/nsp3763T763MaCgaTg11AY.360.000148
ORF1ab/nsp3763T763MaCgaTg11AY.370.000316
ORF1ab/nsp3763T763MaCgaTg11AY.39.10.00004
ORF1ab/nsp3763T763MaCgaTg11AY.50.000021
ORF1ab/nsp3763T763MaCgaTg11AY.520.000814
ORF1ab/nsp3763T763MaCgaTg11AY.540.000095
ORF1ab/nsp3763T763MaCgaTg11AY.60.000041
ORF1ab/nsp3763T763MaCgaTg11AY.70.000196
ORF1ab/nsp3763T763MaCgaTg11AY.730.000665
ORF1ab/nsp3763T763MaCgaTg11AY.9.20.000037
ORF1ab/nsp3763T763MaCgaTg11AY.980.000079
ORF1ab/nsp3763T763MaCgaTg11B.1.1.1980.001468
ORF1ab/nsp3763T763MaCgaTg11B.1.1.2630.001558
ORF1ab/nsp3763T763MaCgaTg11B.1.1.3750.011905
ORF1ab/nsp3763T763MaCgaTg11B.1.1.630.000386
ORF1ab/nsp3763T763MaCgaTg11B.1.1.700.000341
ORF1ab/nsp3763T763MaCgaTg11B.1.120.008
ORF1ab/nsp3763T763MaCgaTg11B.1.160.320.004292
ORF1ab/nsp3763T763MaCgaTg11B.1.177.860.000183
ORF1ab/nsp3763T763MaCgaTg11B.1.214.20.0006
ORF1ab/nsp3763T763MaCgaTg11B.1.221.30.000833
ORF1ab/nsp3763T763MaCgaTg11B.1.2340.000132
ORF1ab/nsp3763T763MaCgaTg11B.1.2400.000216
ORF1ab/nsp3763T763MaCgaTg11B.1.2410.000812
ORF1ab/nsp3763T763MaCgaTg11B.1.2580.000067
ORF1ab/nsp3763T763MaCgaTg11B.1.258.110.000396
ORF1ab/nsp3763T763MaCgaTg11B.1.258.140.00098
ORF1ab/nsp3763T763MaCgaTg11B.1.258.70.001912
ORF1ab/nsp3763T763MaCgaTg11B.1.3910.001127
ORF1ab/nsp3763T763MaCgaTg11B.1.4970.000315
ORF1ab/nsp3763T763MaCgaTg11B.1.5090.000866
ORF1ab/nsp3763T763MaCgaTg11B.1.5610.000397
ORF1ab/nsp3763T763MaCgaTg11B.1.5820.000491
ORF1ab/nsp3763T763MaCgaTg11B.1.5950.000261
ORF1ab/nsp3763T763MaCgaTg11B.1.6090.000479
ORF1ab/nsp3763T763MaCgaTg11B.1.6300.005236
ORF1ab/nsp3763T763MaCgaTg11B.550.00295
ORF1ab/nsp3763T763MaCgaTg11C.160.00106
ORF1ab/nsp3763T763MaCgaTg11C.370.000116
ORF1ab/nsp3763T763MaCgaTg11P.1.150.000232
ORF1ab/nsp3763T763MaCgaTg11P.30.001595
ORF1ab/nsp3763T763MaCgaTg11Q.80.000165
ORF1ab/nsp3763T763MaCgaTg11U.30.003861

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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