CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = T725I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3725T725IT1543InonsynaCaaTa774077380.9997424892-4894
ORF1ab/nsp3725T725IT1543InonsynaCAaTT774020.0002583984892-4894

Details of the mutation T725I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3725T725IaCaaTa77387740All0.00148
ORF1ab/nsp3725T725IaCAaTT27740All0
ORF1ab/nsp3725T725IaCaaTa25332533B.1.1.70.002268
ORF1ab/nsp3725T725IaCaaTa821821AY.40.001278
ORF1ab/nsp3725T725IaCaaTa610610B.1.258.160.998363
ORF1ab/nsp3725T725IaCaaTa446446B.1.617.20.001679
ORF1ab/nsp3725T725IaCaaTa418418AY.30.004158
ORF1ab/nsp3725T725IaCaaTa271271AY.250.00163
ORF1ab/nsp3725T725IaCaaTa131131B.1.2580.008718
ORF1ab/nsp3725T725IaCaaTa112112AY.440.000682
ORF1ab/nsp3725T725IaCaaTa101101B.1.20.000889
ORF1ab/nsp3725T725IaCaaTa100100AY.430.000443
ORF1ab/nsp3725T725IaCaaTa9090AY.1030.000559
ORF1ab/nsp3725T725IaCaaTa8383B.1.4290.001953
ORF1ab/nsp3725T725IaCaaTa7575B.10.000687
ORF1ab/nsp3725T725IaCaaTa7575B.1.10.001361
ORF1ab/nsp3725T725IaCaaTa7474B.1.1600.002308
ORF1ab/nsp3725T725IaCaaTa7171AY.1200.00264
ORF1ab/nsp3725T725IaCaaTa6464B.1.1.280.019919
ORF1ab/nsp3725T725IaCaaTa6060A.2.50.02994
ORF1ab/nsp3725T725IaCaaTa6060B.1.1770.00079
ORF1ab/nsp3725T725IaCaaTa5252AY.160.019742
ORF1ab/nsp3725T725IaCaaTa5151AY.360.007559
ORF1ab/nsp3725T725IaCaaTa4949AY.1210.006631
ORF1ab/nsp3725T725IaCaaTa4747AY.330.003139
ORF1ab/nsp3725T725IaCaaTa4747B.1.2400.010131
ORF1ab/nsp3725T725IaCaaTa4242B.1.36.340.893617
ORF1ab/nsp3725T725IaCaaTa4141P.10.000646
ORF1ab/nsp3725T725IaCaaTa3939AY.70.007644
ORF1ab/nsp3725T725IaCaaTa3737AY.390.000914
ORF1ab/nsp3725T725IaCaaTa3535AY.4.20.000759
ORF1ab/nsp3725T725IaCaaTa3535B.6.60.031111
ORF1ab/nsp3725T725IaCaaTa3434B.1.3510.001011
ORF1ab/nsp3725T725IaCaaTa3333B.1.177.370.891892
ORF1ab/nsp3725T725IaCaaTa3030AY.1020.000795
ORF1ab/nsp3725T725IaCaaTa3030B.1.5260.000705
ORF1ab/nsp3725T725IaCaaTa2727AY.590.014301
ORF1ab/nsp3725T725IaCaaTa2525B.1.1.2140.001386
ORF1ab/nsp3725T725IaCaaTa2424B.1.1.330.010101
ORF1ab/nsp3725T725IaCaaTa2323AY.1170.001944
ORF1ab/nsp3725T725IaCaaTa2121B.1.1.2070.024823
ORF1ab/nsp3725T725IaCaaTa2020AY.980.00158
ORF1ab/nsp3725T725IaCaaTa2020B.1.177.540.012129
ORF1ab/nsp3725T725IaCaaTa1919B.1.1.3170.007822
ORF1ab/nsp3725T725IaCaaTa1818AY.140.001584
ORF1ab/nsp3725T725IaCaaTa1717AY.260.000481
ORF1ab/nsp3725T725IaCaaTa1717AY.4.50.001827
ORF1ab/nsp3725T725IaCaaTa1717AY.46.50.003373
ORF1ab/nsp3725T725IaCaaTa1616B0.002045
ORF1ab/nsp3725T725IaCaaTa1616B.1.1.2840.001718
ORF1ab/nsp3725T725IaCaaTa1616B.1.177.420.014311
ORF1ab/nsp3725T725IaCaaTa1515AY.50.00031
ORF1ab/nsp3725T725IaCaaTa1414AY.610.001467
ORF1ab/nsp3725T725IaCaaTa1414B.1.1.5190.000556
ORF1ab/nsp3725T725IaCaaTa1212AY.1190.000424
ORF1ab/nsp3725T725IaCaaTa1212AY.9.10.001005
ORF1ab/nsp3725T725IaCaaTa1010AY.1110.001832
ORF1ab/nsp3725T725IaCaaTa1010AY.200.000389
ORF1ab/nsp3725T725IaCaaTa1010AY.910.007305
ORF1ab/nsp3725T725IaCaaTa1010B.1.3750.008197
ORF1ab/nsp3725T725IaCaaTa1010B.1.617.10.00129
ORF1ab/nsp3725T725IaCaaTa1010B.1.6370.000731
ORF1ab/nsp3725T725IaCaaTa99AY.240.003879
ORF1ab/nsp3725T725IaCaaTa99B.1.1.2220.001836
ORF1ab/nsp3725T725IaCaaTa99B.1.258.170.000936
ORF1ab/nsp3725T725IaCaaTa99B.1.4270.000454
ORF1ab/nsp3725T725IaCaaTa88AY.290.000126
ORF1ab/nsp3725T725IaCaaTa88AY.46.60.000578
ORF1ab/nsp3725T725IaCaaTa88AY.510.007273
ORF1ab/nsp3725T725IaCaaTa88AY.9.20.000294
ORF1ab/nsp3725T725IaCaaTa88B.1.177.80.00602
ORF1ab/nsp3725T725IaCaaTa88B.1.2320.004299
ORF1ab/nsp3725T725IaCaaTa88B.1.2430.000557
ORF1ab/nsp3725T725IaCaaTa88B.1.3690.002282
ORF1ab/nsp3725T725IaCaaTa88B.1.4660.186047
ORF1ab/nsp3725T725IaCaaTa77AY.1000.000322
ORF1ab/nsp3725T725IaCaaTa77AY.420.000282
ORF1ab/nsp3725T725IaCaaTa77AY.750.000392
ORF1ab/nsp3725T725IaCaaTa77AY.790.008475
ORF1ab/nsp3725T725IaCaaTa77B.1.1.1860.024055
ORF1ab/nsp3725T725IaCaaTa77B.1.177.210.000535
ORF1ab/nsp3725T725IaCaaTa77B.1.5170.002989
ORF1ab/nsp3725T725IaCaaTa77B.1.5230.017157
ORF1ab/nsp3725T725IaCaaTa77P.1.170.001132
ORF1ab/nsp3725T725IaCaaTa66AY.60.000247
ORF1ab/nsp3725T725IaCaaTa66AY.99.20.000553
ORF1ab/nsp3725T725IaCaaTa66B.1.2340.000792
ORF1ab/nsp3725T725IaCaaTa66B.1.2360.01232
ORF1ab/nsp3725T725IaCaaTa66B.1.466.20.002347
ORF1ab/nsp3725T725IaCaaTa66B.1.5510.007742
ORF1ab/nsp3725T725IaCaaTa66C.370.000696
ORF1ab/nsp3725T725IaCaaTa55AY.1060.001674
ORF1ab/nsp3725T725IaCaaTa55AY.120.00158
ORF1ab/nsp3725T725IaCaaTa55AY.90.000338
ORF1ab/nsp3725T725IaCaaTa55B.1.1.630.001929
ORF1ab/nsp3725T725IaCaaTa55B.1.2210.000355
ORF1ab/nsp3725T725IaCaaTa55B.1.36.240.030864
ORF1ab/nsp3725T725IaCaaTa55B.1.6090.002397
ORF1ab/nsp3725T725IaCaaTa55D.20.000375
ORF1ab/nsp3725T725IaCAaTT240.111111
ORF1ab/nsp3725T725IaCaaTa240.111111
ORF1ab/nsp3725T725IaCaaTa44AY.1010.001962
ORF1ab/nsp3725T725IaCaaTa44AY.29.10.000882
ORF1ab/nsp3725T725IaCaaTa44AY.470.000124
ORF1ab/nsp3725T725IaCaaTa44AY.98.10.000194
ORF1ab/nsp3725T725IaCaaTa44B.1.1.700.001364
ORF1ab/nsp3725T725IaCaaTa44B.1.1080.023256
ORF1ab/nsp3725T725IaCaaTa44B.1.177.40.000844
ORF1ab/nsp3725T725IaCaaTa44B.1.360.000584
ORF1ab/nsp3725T725IaCaaTa44B.1.5960.000349
ORF1ab/nsp3725T725IaCaaTa44R.10.00036
ORF1ab/nsp3725T725IaCaaTa33A.270.004967
ORF1ab/nsp3725T725IaCaaTa33AT.10.015385
ORF1ab/nsp3725T725IaCaaTa33AY.1100.000338
ORF1ab/nsp3725T725IaCaaTa33AY.1130.000427
ORF1ab/nsp3725T725IaCaaTa33AY.1160.00086
ORF1ab/nsp3725T725IaCaaTa33AY.1180.000188
ORF1ab/nsp3725T725IaCaaTa33AY.130.000483
ORF1ab/nsp3725T725IaCaaTa33AY.230.000209
ORF1ab/nsp3725T725IaCaaTa33AY.270.000194
ORF1ab/nsp3725T725IaCaaTa33AY.5.40.00083
ORF1ab/nsp3725T725IaCaaTa33AY.550.002752
ORF1ab/nsp3725T725IaCaaTa33AY.710.001425
ORF1ab/nsp3725T725IaCaaTa33AY.75.10.000541
ORF1ab/nsp3725T725IaCaaTa33AY.920.000862
ORF1ab/nsp3725T725IaCaaTa33B.1.177.560.002003
ORF1ab/nsp3725T725IaCaaTa33B.1.177.860.00055
ORF1ab/nsp3725T725IaCaaTa33B.1.36.380.004926
ORF1ab/nsp3725T725IaCaaTa33B.1.3970.014563
ORF1ab/nsp3725T725IaCaaTa33B.1.4260.003027
ORF1ab/nsp3725T725IaCaaTa33B.1.5250.000339
ORF1ab/nsp3725T725IaCaaTa33B.1.6100.010638
ORF1ab/nsp3725T725IaCaaTa33B.1.6210.000266
ORF1ab/nsp3725T725IaCaaTa33P.1.140.000143
ORF1ab/nsp3725T725IaCaaTa33P.20.00056
ORF1ab/nsp3725T725IaCaaTa22AU.20.004843
ORF1ab/nsp3725T725IaCaaTa22AY.1090.001479
ORF1ab/nsp3725T725IaCaaTa22AY.120.10.000642
ORF1ab/nsp3725T725IaCaaTa22AY.210.003795
ORF1ab/nsp3725T725IaCaaTa22AY.3.10.000171
ORF1ab/nsp3725T725IaCaaTa22AY.350.000466
ORF1ab/nsp3725T725IaCaaTa22AY.39.10.000079
ORF1ab/nsp3725T725IaCaaTa22AY.450.000243
ORF1ab/nsp3725T725IaCaaTa22AY.460.000208
ORF1ab/nsp3725T725IaCaaTa22AY.540.000191
ORF1ab/nsp3725T725IaCaaTa22AY.580.001815
ORF1ab/nsp3725T725IaCaaTa22AY.700.000417
ORF1ab/nsp3725T725IaCaaTa22AY.740.000231
ORF1ab/nsp3725T725IaCaaTa22AY.99.10.003106
ORF1ab/nsp3725T725IaCaaTa22B.1.1.10.000653
ORF1ab/nsp3725T725IaCaaTa22B.1.1.3000.021505
ORF1ab/nsp3725T725IaCaaTa22B.1.1.3780.014599
ORF1ab/nsp3725T725IaCaaTa22B.1.1.4320.002532
ORF1ab/nsp3725T725IaCaaTa22B.1.1.4480.004065
ORF1ab/nsp3725T725IaCaaTa22B.1.1.4640.002946
ORF1ab/nsp3725T725IaCaaTa22B.1.1280.001271
ORF1ab/nsp3725T725IaCaaTa22B.1.160.280.005848
ORF1ab/nsp3725T725IaCaaTa22B.1.36.290.001035
ORF1ab/nsp3725T725IaCaaTa22B.1.3980.005952
ORF1ab/nsp3725T725IaCaaTa22B.1.4090.001563
ORF1ab/nsp3725T725IaCaaTa22B.1.6180.008065
ORF1ab/nsp3725T725IaCaaTa22C.330.117647
ORF1ab/nsp3725T725IaCaaTa22N.30.011628
ORF1ab/nsp3725T725IaCaaTa11A0.000387
ORF1ab/nsp3725T725IaCaaTa11A.2.30.004739
ORF1ab/nsp3725T725IaCaaTa11A.23.10.000704
ORF1ab/nsp3725T725IaCaaTa11AE.50.018519
ORF1ab/nsp3725T725IaCaaTa11AY.10.000396
ORF1ab/nsp3725T725IaCaaTa11AY.120.2.10.000498
ORF1ab/nsp3725T725IaCaaTa11AY.340.000097
ORF1ab/nsp3725T725IaCaaTa11AY.34.10.00051
ORF1ab/nsp3725T725IaCaaTa11AY.370.000316
ORF1ab/nsp3725T725IaCaaTa11AY.4.10.000737
ORF1ab/nsp3725T725IaCaaTa11AY.4.2.10.000149
ORF1ab/nsp3725T725IaCaaTa11AY.410.000294
ORF1ab/nsp3725T725IaCaaTa11AY.46.10.001027
ORF1ab/nsp3725T725IaCaaTa11AY.46.40.000165
ORF1ab/nsp3725T725IaCaaTa11AY.5.20.002463
ORF1ab/nsp3725T725IaCaaTa11AY.530.000288
ORF1ab/nsp3725T725IaCaaTa11AY.670.000464
ORF1ab/nsp3725T725IaCaaTa11AY.7.10.000113
ORF1ab/nsp3725T725IaCaaTa11AY.7.20.000559
ORF1ab/nsp3725T725IaCaaTa11AY.770.001127
ORF1ab/nsp3725T725IaCaaTa11AY.80.000606
ORF1ab/nsp3725T725IaCaaTa11AY.930.000273
ORF1ab/nsp3725T725IaCaaTa11AY.950.000761
ORF1ab/nsp3725T725IaCaaTa11B.1.1.1210.002427
ORF1ab/nsp3725T725IaCaaTa11B.1.1.1770.019231
ORF1ab/nsp3725T725IaCaaTa11B.1.1.2160.00089
ORF1ab/nsp3725T725IaCaaTa11B.1.1.2200.001859
ORF1ab/nsp3725T725IaCaaTa11B.1.1.2390.032258
ORF1ab/nsp3725T725IaCaaTa11B.1.1.3020.002075
ORF1ab/nsp3725T725IaCaaTa11B.1.1.3050.003861
ORF1ab/nsp3725T725IaCaaTa11B.1.1.3060.000438
ORF1ab/nsp3725T725IaCaaTa11B.1.1.3070.002532
ORF1ab/nsp3725T725IaCaaTa11B.1.1.3290.003846
ORF1ab/nsp3725T725IaCaaTa11B.1.1.3480.000796
ORF1ab/nsp3725T725IaCaaTa11B.1.1.370.000193
ORF1ab/nsp3725T725IaCaaTa11B.1.1.4070.041667
ORF1ab/nsp3725T725IaCaaTa11B.1.1.410.006329
ORF1ab/nsp3725T725IaCaaTa11B.1.1.4130.006897
ORF1ab/nsp3725T725IaCaaTa11B.1.1.4160.000905
ORF1ab/nsp3725T725IaCaaTa11B.1.1.4200.001006
ORF1ab/nsp3725T725IaCaaTa11B.1.1.4660.008696
ORF1ab/nsp3725T725IaCaaTa11B.1.1.530.013699
ORF1ab/nsp3725T725IaCaaTa11B.1.1.540.003021
ORF1ab/nsp3725T725IaCaaTa11B.1.1.770.041667
ORF1ab/nsp3725T725IaCaaTa11B.1.1110.001175
ORF1ab/nsp3725T725IaCaaTa11B.1.1150.021739
ORF1ab/nsp3725T725IaCaaTa11B.1.1310.008772
ORF1ab/nsp3725T725IaCaaTa11B.1.1470.000756
ORF1ab/nsp3725T725IaCaaTa11B.1.1490.003425
ORF1ab/nsp3725T725IaCaaTa11B.1.160.260.002421
ORF1ab/nsp3725T725IaCaaTa11B.1.1690.014925
ORF1ab/nsp3725T725IaCaaTa11B.1.177.110.001698
ORF1ab/nsp3725T725IaCaaTa11B.1.177.230.003236
ORF1ab/nsp3725T725IaCaaTa11B.1.177.570.000281
ORF1ab/nsp3725T725IaCaaTa11B.1.177.70.000165
ORF1ab/nsp3725T725IaCaaTa11B.1.177.770.000726
ORF1ab/nsp3725T725IaCaaTa11B.1.177.800.001912
ORF1ab/nsp3725T725IaCaaTa11B.1.177.850.005435
ORF1ab/nsp3725T725IaCaaTa11B.1.1790.003759
ORF1ab/nsp3725T725IaCaaTa11B.1.2010.005682
ORF1ab/nsp3725T725IaCaaTa11B.1.2060.000816
ORF1ab/nsp3725T725IaCaaTa11B.1.2140.003663
ORF1ab/nsp3725T725IaCaaTa11B.1.214.20.0006
ORF1ab/nsp3725T725IaCaaTa11B.1.2220.001692
ORF1ab/nsp3725T725IaCaaTa11B.1.258.110.000396
ORF1ab/nsp3725T725IaCaaTa11B.1.258.40.003448
ORF1ab/nsp3725T725IaCaaTa11B.1.2600.003344
ORF1ab/nsp3725T725IaCaaTa11B.1.2980.002114
ORF1ab/nsp3725T725IaCaaTa11B.1.30.002618
ORF1ab/nsp3725T725IaCaaTa11B.1.3110.000275
ORF1ab/nsp3725T725IaCaaTa11B.1.3490.000715
ORF1ab/nsp3725T725IaCaaTa11B.1.36.220.001208
ORF1ab/nsp3725T725IaCaaTa11B.1.4240.008065
ORF1ab/nsp3725T725IaCaaTa11B.1.4680.005714
ORF1ab/nsp3725T725IaCaaTa11B.1.4990.00105
ORF1ab/nsp3725T725IaCaaTa11B.1.5460.003704
ORF1ab/nsp3725T725IaCaaTa11B.1.5760.000907
ORF1ab/nsp3725T725IaCaaTa11B.1.5800.004065
ORF1ab/nsp3725T725IaCaaTa11B.1.5950.000261
ORF1ab/nsp3725T725IaCaaTa11B.1.621.10.000506
ORF1ab/nsp3725T725IaCaaTa11B.230.002924
ORF1ab/nsp3725T725IaCaaTa11B.30.000831
ORF1ab/nsp3725T725IaCaaTa11B.350.007812
ORF1ab/nsp3725T725IaCaaTa11B.400.000364
ORF1ab/nsp3725T725IaCaaTa11B.60.00091
ORF1ab/nsp3725T725IaCaaTa11B.6.40.045455
ORF1ab/nsp3725T725IaCaaTa11C.160.00106
ORF1ab/nsp3725T725IaCaaTa11C.180.002591
ORF1ab/nsp3725T725IaCaaTa11C.400.027778
ORF1ab/nsp3725T725IaCaaTa11N.50.001767
ORF1ab/nsp3725T725IaCaaTa11P.1.10.000318
ORF1ab/nsp3725T725IaCaaTa11P.1.20.001156
ORF1ab/nsp3725T725IaCaaTa11Q.10.000126
ORF1ab/nsp3725T725IaCaaTa11Q.80.000165
ORF1ab/nsp3725T725IaCaaTa11Y.10.012821

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.