CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = T424T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3424T424TT1242TsynacTacC2231500.6726463989-3991
ORF1ab/nsp3424T424TT1242TsynacTacG223620.2780273989-3991
ORF1ab/nsp3424T424TT1242TsynacTacA223110.04932743989-3991

Details of the mutation T424T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3424T424TacTacC150223All0.000029
ORF1ab/nsp3424T424TacTacG62223All0.000012
ORF1ab/nsp3424T424TacTacA11223All0.000002
ORF1ab/nsp3424T424TacTacC4748B.1.20.000414
ORF1ab/nsp3424T424TacTacA148B.1.20.000009
ORF1ab/nsp3424T424TacTacC4545AY.240.019397
ORF1ab/nsp3424T424TacTacG1620B.1.1.70.000014
ORF1ab/nsp3424T424TacTacC320B.1.1.70.000003
ORF1ab/nsp3424T424TacTacA120B.1.1.70.000001
ORF1ab/nsp3424T424TacTacC1114AY.40.000017
ORF1ab/nsp3424T424TacTacA214AY.40.000003
ORF1ab/nsp3424T424TacTacG114AY.40.000002
ORF1ab/nsp3424T424TacTacG1214B.1.1770.000158
ORF1ab/nsp3424T424TacTacA214B.1.1770.000026
ORF1ab/nsp3424T424TacTacC712B.1.617.20.000026
ORF1ab/nsp3424T424TacTacG512B.1.617.20.000019
ORF1ab/nsp3424T424TacTacC57AY.1210.000677
ORF1ab/nsp3424T424TacTacG27AY.1210.000271
ORF1ab/nsp3424T424TacTacG56AY.1030.000031
ORF1ab/nsp3424T424TacTacC16AY.1030.000006
ORF1ab/nsp3424T424TacTacC35AY.250.000018
ORF1ab/nsp3424T424TacTacG25AY.250.000012
ORF1ab/nsp3424T424TacTacC35AY.430.000013
ORF1ab/nsp3424T424TacTacG15AY.430.000004
ORF1ab/nsp3424T424TacTacA15AY.430.000004
ORF1ab/nsp3424T424TacTacG25B.10.000018
ORF1ab/nsp3424T424TacTacC25B.10.000018
ORF1ab/nsp3424T424TacTacA15B.10.000009
ORF1ab/nsp3424T424TacTacG23AY.30.00002
ORF1ab/nsp3424T424TacTacC13AY.30.00001
ORF1ab/nsp3424T424TacTacG23AY.440.000012
ORF1ab/nsp3424T424TacTacC13AY.440.000006
ORF1ab/nsp3424T424TacTacG33B.1.6200.002838
ORF1ab/nsp3424T424TacTacG22AY.160.000759
ORF1ab/nsp3424T424TacTacC22AY.50.000041
ORF1ab/nsp3424T424TacTacA12B.1.10.000018
ORF1ab/nsp3424T424TacTacC12B.1.10.000018
ORF1ab/nsp3424T424TacTacC22B.1.2430.000139
ORF1ab/nsp3424T424TacTacC11A.2.50.000499
ORF1ab/nsp3424T424TacTacC11AE.80.000489
ORF1ab/nsp3424T424TacTacC11AY.1000.000046
ORF1ab/nsp3424T424TacTacG11AY.1020.000027
ORF1ab/nsp3424T424TacTacC11AY.1130.000142
ORF1ab/nsp3424T424TacTacG11AY.34.10.00051
ORF1ab/nsp3424T424TacTacC11AY.4.20.000022
ORF1ab/nsp3424T424TacTacC11AY.590.00053
ORF1ab/nsp3424T424TacTacC11AY.60.000041
ORF1ab/nsp3424T424TacTacG11AY.610.000105
ORF1ab/nsp3424T424TacTacC11AY.790.001211
ORF1ab/nsp3424T424TacTacG11B.1.1.280.000311
ORF1ab/nsp3424T424TacTacC11B.1.1.3260.001761
ORF1ab/nsp3424T424TacTacC11B.1.1.5190.00004
ORF1ab/nsp3424T424TacTacC11B.1.110.30.000718
ORF1ab/nsp3424T424TacTacC11B.1.177.870.000728
ORF1ab/nsp3424T424TacTacG11B.1.214.20.0006
ORF1ab/nsp3424T424TacTacA11B.1.3960.000706
ORF1ab/nsp3424T424TacTacA11B.1.4270.00005
ORF1ab/nsp3424T424TacTacC11B.1.4290.000024
ORF1ab/nsp3424T424TacTacG11B.1.466.20.000391
ORF1ab/nsp3424T424TacTacG11B.1.5430.01
ORF1ab/nsp3424T424TacTacC11B.1.5960.000087
ORF1ab/nsp3424T424TacTacC11B.1.619.10.000641
ORF1ab/nsp3424T424TacTacC11B.6.60.000889

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.