CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = T237I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3237T237IT1055InonsynaCaaTa3248324813428-3430

Details of the mutation T237I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3237T237IaCaaTa32483248All0.000621
ORF1ab/nsp3237T237IaCaaTa675675B.1.1.70.000604
ORF1ab/nsp3237T237IaCaaTa317317AY.430.001404
ORF1ab/nsp3237T237IaCaaTa278278AY.40.000433
ORF1ab/nsp3237T237IaCaaTa240240AY.440.001461
ORF1ab/nsp3237T237IaCaaTa228228B.1.617.20.000859
ORF1ab/nsp3237T237IaCaaTa201201D.51
ORF1ab/nsp3237T237IaCaaTa140140AY.30.001392
ORF1ab/nsp3237T237IaCaaTa115115B.1.2580.007653
ORF1ab/nsp3237T237IaCaaTa109109AY.1000.005015
ORF1ab/nsp3237T237IaCaaTa5252B.1.3510.001546
ORF1ab/nsp3237T237IaCaaTa4646B.1.10.000834
ORF1ab/nsp3237T237IaCaaTa4040B.1.1770.000527
ORF1ab/nsp3237T237IaCaaTa3939B.1.20.000343
ORF1ab/nsp3237T237IaCaaTa3434AY.1030.000211
ORF1ab/nsp3237T237IaCaaTa3434B.10.000311
ORF1ab/nsp3237T237IaCaaTa3434C.370.003946
ORF1ab/nsp3237T237IaCaaTa3333AY.250.000198
ORF1ab/nsp3237T237IaCaaTa3030AY.260.000849
ORF1ab/nsp3237T237IaCaaTa2424AY.420.000966
ORF1ab/nsp3237T237IaCaaTa2424P.10.000378
ORF1ab/nsp3237T237IaCaaTa1919B.1.1.5190.000755
ORF1ab/nsp3237T237IaCaaTa1818AY.200.0007
ORF1ab/nsp3237T237IaCaaTa1818B.1.4290.000424
ORF1ab/nsp3237T237IaCaaTa1616AY.330.001068
ORF1ab/nsp3237T237IaCaaTa1616C.1.20.068085
ORF1ab/nsp3237T237IaCaaTa1515AY.290.000237
ORF1ab/nsp3237T237IaCaaTa1515AY.980.001185
ORF1ab/nsp3237T237IaCaaTa1414AY.50.000289
ORF1ab/nsp3237T237IaCaaTa1414B.1.2340.001847
ORF1ab/nsp3237T237IaCaaTa1212B.1.4270.000606
ORF1ab/nsp3237T237IaCaaTa1010AY.46.20.006353
ORF1ab/nsp3237T237IaCaaTa1010B.1.5260.000235
ORF1ab/nsp3237T237IaCaaTa99AY.1130.001282
ORF1ab/nsp3237T237IaCaaTa99AY.1190.000318
ORF1ab/nsp3237T237IaCaaTa99AY.98.10.000436
ORF1ab/nsp3237T237IaCaaTa99B.1.177.690.013353
ORF1ab/nsp3237T237IaCaaTa99B.1.3240.014446
ORF1ab/nsp3237T237IaCaaTa88AY.1020.000212
ORF1ab/nsp3237T237IaCaaTa77AY.1210.000947
ORF1ab/nsp3237T237IaCaaTa77AY.4.20.000152
ORF1ab/nsp3237T237IaCaaTa77AY.460.000729
ORF1ab/nsp3237T237IaCaaTa77AY.5.20.017241
ORF1ab/nsp3237T237IaCaaTa77B.1.1280.004447
ORF1ab/nsp3237T237IaCaaTa77C.36.30.003971
ORF1ab/nsp3237T237IaCaaTa77P.1.140.000335
ORF1ab/nsp3237T237IaCaaTa66AY.390.000148
ORF1ab/nsp3237T237IaCaaTa66AY.610.000629
ORF1ab/nsp3237T237IaCaaTa55AY.3.10.000426
ORF1ab/nsp3237T237IaCaaTa55AY.320.002662
ORF1ab/nsp3237T237IaCaaTa55AY.450.000608
ORF1ab/nsp3237T237IaCaaTa55AY.750.00028
ORF1ab/nsp3237T237IaCaaTa55AY.850.002136
ORF1ab/nsp3237T237IaCaaTa55B.1.1.2770.003794
ORF1ab/nsp3237T237IaCaaTa55B.1.1.330.002104
ORF1ab/nsp3237T237IaCaaTa55B.1.5960.000436
ORF1ab/nsp3237T237IaCaaTa55B.1.6090.002397
ORF1ab/nsp3237T237IaCaaTa55C.160.005302
ORF1ab/nsp3237T237IaCaaTa44AY.116.10.001246
ORF1ab/nsp3237T237IaCaaTa44AY.39.10.000158
ORF1ab/nsp3237T237IaCaaTa44AY.46.60.000289
ORF1ab/nsp3237T237IaCaaTa44B.1.1.410.025316
ORF1ab/nsp3237T237IaCaaTa44B.1.1600.000125
ORF1ab/nsp3237T237IaCaaTa44B.1.360.000584
ORF1ab/nsp3237T237IaCaaTa44B.1.3960.002823
ORF1ab/nsp3237T237IaCaaTa44B.1.4370.083333
ORF1ab/nsp3237T237IaCaaTa44B.1.6200.003784
ORF1ab/nsp3237T237IaCaaTa44C.360.003643
ORF1ab/nsp3237T237IaCaaTa33AY.1200.000112
ORF1ab/nsp3237T237IaCaaTa33AY.230.000209
ORF1ab/nsp3237T237IaCaaTa33AY.470.000093
ORF1ab/nsp3237T237IaCaaTa33AY.540.000286
ORF1ab/nsp3237T237IaCaaTa33AY.620.001307
ORF1ab/nsp3237T237IaCaaTa33AY.7.10.000338
ORF1ab/nsp3237T237IaCaaTa33B.1.1.10.00098
ORF1ab/nsp3237T237IaCaaTa33B.1.1.2140.000166
ORF1ab/nsp3237T237IaCaaTa33B.1.1.3480.002389
ORF1ab/nsp3237T237IaCaaTa33B.1.1.370.000579
ORF1ab/nsp3237T237IaCaaTa33B.1.1.4090.008499
ORF1ab/nsp3237T237IaCaaTa33B.1.258.170.000312
ORF1ab/nsp3237T237IaCaaTa33B.1.36.290.001552
ORF1ab/nsp3237T237IaCaaTa33B.1.3670.002377
ORF1ab/nsp3237T237IaCaaTa33B.1.466.20.001174
ORF1ab/nsp3237T237IaCaaTa33B.1.6350.052632
ORF1ab/nsp3237T237IaCaaTa33D.20.000225
ORF1ab/nsp3237T237IaCaaTa33N.30.017442
ORF1ab/nsp3237T237IaCaaTa33P.1.10.000953
ORF1ab/nsp3237T237IaCaaTa22AD.20.000438
ORF1ab/nsp3237T237IaCaaTa22AU.10.002532
ORF1ab/nsp3237T237IaCaaTa22AY.1070.000932
ORF1ab/nsp3237T237IaCaaTa22AY.1170.000169
ORF1ab/nsp3237T237IaCaaTa22AY.130.000322
ORF1ab/nsp3237T237IaCaaTa22AY.5.40.000553
ORF1ab/nsp3237T237IaCaaTa22B.1.1.2010.04878
ORF1ab/nsp3237T237IaCaaTa22B.1.1.2160.001781
ORF1ab/nsp3237T237IaCaaTa22B.1.1.2550.006061
ORF1ab/nsp3237T237IaCaaTa22B.1.1.280.000622
ORF1ab/nsp3237T237IaCaaTa22B.1.1.610.017544
ORF1ab/nsp3237T237IaCaaTa22B.1.177.740.030303
ORF1ab/nsp3237T237IaCaaTa22B.1.258.180.2
ORF1ab/nsp3237T237IaCaaTa22B.1.36.80.002
ORF1ab/nsp3237T237IaCaaTa22B.1.4700.002809
ORF1ab/nsp3237T237IaCaaTa22B.1.5610.000794
ORF1ab/nsp3237T237IaCaaTa22B.1.617.10.000258
ORF1ab/nsp3237T237IaCaaTa22B.1.6190.001742
ORF1ab/nsp3237T237IaCaaTa22B.1.6230.001073
ORF1ab/nsp3237T237IaCaaTa22B.400.000729
ORF1ab/nsp3237T237IaCaaTa22B.60.00182
ORF1ab/nsp3237T237IaCaaTa22C.10.004785
ORF1ab/nsp3237T237IaCaaTa11A.23.10.000704
ORF1ab/nsp3237T237IaCaaTa11A.270.001656
ORF1ab/nsp3237T237IaCaaTa11AK.10.012658
ORF1ab/nsp3237T237IaCaaTa11AY.10.000396
ORF1ab/nsp3237T237IaCaaTa11AY.1010.00049
ORF1ab/nsp3237T237IaCaaTa11AY.1100.000113
ORF1ab/nsp3237T237IaCaaTa11AY.1160.000287
ORF1ab/nsp3237T237IaCaaTa11AY.1180.000063
ORF1ab/nsp3237T237IaCaaTa11AY.120.2.10.000498
ORF1ab/nsp3237T237IaCaaTa11AY.160.00038
ORF1ab/nsp3237T237IaCaaTa11AY.20.000356
ORF1ab/nsp3237T237IaCaaTa11AY.270.000065
ORF1ab/nsp3237T237IaCaaTa11AY.29.10.000221
ORF1ab/nsp3237T237IaCaaTa11AY.300.000396
ORF1ab/nsp3237T237IaCaaTa11AY.340.000097
ORF1ab/nsp3237T237IaCaaTa11AY.4.30.000842
ORF1ab/nsp3237T237IaCaaTa11AY.46.40.000165
ORF1ab/nsp3237T237IaCaaTa11AY.490.003195
ORF1ab/nsp3237T237IaCaaTa11AY.5.30.000337
ORF1ab/nsp3237T237IaCaaTa11AY.530.000288
ORF1ab/nsp3237T237IaCaaTa11AY.570.000656
ORF1ab/nsp3237T237IaCaaTa11AY.60.000041
ORF1ab/nsp3237T237IaCaaTa11AY.650.000533
ORF1ab/nsp3237T237IaCaaTa11AY.670.000464
ORF1ab/nsp3237T237IaCaaTa11AY.740.000116
ORF1ab/nsp3237T237IaCaaTa11AY.840.000437
ORF1ab/nsp3237T237IaCaaTa11AY.9.20.000037
ORF1ab/nsp3237T237IaCaaTa11AY.930.000273
ORF1ab/nsp3237T237IaCaaTa11B0.000128
ORF1ab/nsp3237T237IaCaaTa11B.1.1.100.001115
ORF1ab/nsp3237T237IaCaaTa11B.1.1.1610.003534
ORF1ab/nsp3237T237IaCaaTa11B.1.1.1660.033333
ORF1ab/nsp3237T237IaCaaTa11B.1.1.1890.001513
ORF1ab/nsp3237T237IaCaaTa11B.1.1.2630.001558
ORF1ab/nsp3237T237IaCaaTa11B.1.1.2830.023256
ORF1ab/nsp3237T237IaCaaTa11B.1.1.2860.002899
ORF1ab/nsp3237T237IaCaaTa11B.1.1.2940.001266
ORF1ab/nsp3237T237IaCaaTa11B.1.1.3060.000438
ORF1ab/nsp3237T237IaCaaTa11B.1.1.3180.000302
ORF1ab/nsp3237T237IaCaaTa11B.1.1.3750.011905
ORF1ab/nsp3237T237IaCaaTa11B.1.1.390.00051
ORF1ab/nsp3237T237IaCaaTa11B.1.1.4160.000905
ORF1ab/nsp3237T237IaCaaTa11B.1.1.700.000341
ORF1ab/nsp3237T237IaCaaTa11B.1.1110.001175
ORF1ab/nsp3237T237IaCaaTa11B.1.1570.002985
ORF1ab/nsp3237T237IaCaaTa11B.1.177.410.0025
ORF1ab/nsp3237T237IaCaaTa11B.1.177.480.003125
ORF1ab/nsp3237T237IaCaaTa11B.1.177.560.000668
ORF1ab/nsp3237T237IaCaaTa11B.1.177.570.000281
ORF1ab/nsp3237T237IaCaaTa11B.1.177.600.000218
ORF1ab/nsp3237T237IaCaaTa11B.1.177.70.000165
ORF1ab/nsp3237T237IaCaaTa11B.1.177.820.000477
ORF1ab/nsp3237T237IaCaaTa11B.1.2210.000071
ORF1ab/nsp3237T237IaCaaTa11B.1.2320.000537
ORF1ab/nsp3237T237IaCaaTa11B.1.2430.00007
ORF1ab/nsp3237T237IaCaaTa11B.1.2790.000514
ORF1ab/nsp3237T237IaCaaTa11B.1.3210.034483
ORF1ab/nsp3237T237IaCaaTa11B.1.3630.012987
ORF1ab/nsp3237T237IaCaaTa11B.1.3980.002976
ORF1ab/nsp3237T237IaCaaTa11B.1.4230.010204
ORF1ab/nsp3237T237IaCaaTa11B.1.4530.003236
ORF1ab/nsp3237T237IaCaaTa11B.1.5090.000866
ORF1ab/nsp3237T237IaCaaTa11B.1.5250.000113
ORF1ab/nsp3237T237IaCaaTa11B.1.5740.002151
ORF1ab/nsp3237T237IaCaaTa11B.1.5750.000303
ORF1ab/nsp3237T237IaCaaTa11B.1.5950.000261
ORF1ab/nsp3237T237IaCaaTa11B.1.930.000934
ORF1ab/nsp3237T237IaCaaTa11C.37.10.002618
ORF1ab/nsp3237T237IaCaaTa11N.50.001767
ORF1ab/nsp3237T237IaCaaTa11P.1.170.000162
ORF1ab/nsp3237T237IaCaaTa11P.70.004367
ORF1ab/nsp3237T237IaCaaTa11Q.10.000126
ORF1ab/nsp3237T237IaCaaTa11Q.40.000455

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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