CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = T1251T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31251T1251TT2069TsynacCacT217017520.8073736470-6472
ORF1ab/nsp31251T1251TT2069TsynacCacA21704180.1926276470-6472

Details of the mutation T1251T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31251T1251TacCacT17522170All0.000335
ORF1ab/nsp31251T1251TacCacA4182170All0.00008
ORF1ab/nsp31251T1251TacCacT531698B.1.1.70.000475
ORF1ab/nsp31251T1251TacCacA167698B.1.1.70.00015
ORF1ab/nsp31251T1251TacCacT120120B.1.2580.007986
ORF1ab/nsp31251T1251TacCacT106116AY.40.000165
ORF1ab/nsp31251T1251TacCacA10116AY.40.000016
ORF1ab/nsp31251T1251TacCacA65109B.1.617.20.000245
ORF1ab/nsp31251T1251TacCacT44109B.1.617.20.000166
ORF1ab/nsp31251T1251TacCacT101102B.1.20.000889
ORF1ab/nsp31251T1251TacCacA1102B.1.20.000009
ORF1ab/nsp31251T1251TacCacT6365AY.99.20.005806
ORF1ab/nsp31251T1251TacCacA265AY.99.20.000184
ORF1ab/nsp31251T1251TacCacT6363B.1.4181
ORF1ab/nsp31251T1251TacCacT3853AY.440.000231
ORF1ab/nsp31251T1251TacCacA1553AY.440.000091
ORF1ab/nsp31251T1251TacCacT4848B.1.2430.00334
ORF1ab/nsp31251T1251TacCacA3745AY.1020.000981
ORF1ab/nsp31251T1251TacCacT845AY.1020.000212
ORF1ab/nsp31251T1251TacCacT2938AY.250.000174
ORF1ab/nsp31251T1251TacCacA938AY.250.000054
ORF1ab/nsp31251T1251TacCacT3238AY.390.000791
ORF1ab/nsp31251T1251TacCacA638AY.390.000148
ORF1ab/nsp31251T1251TacCacT3030B.1.1600.000936
ORF1ab/nsp31251T1251TacCacT3030B.1.5270.111111
ORF1ab/nsp31251T1251TacCacT2626AY.4.20.000564
ORF1ab/nsp31251T1251TacCacT2126B.10.000192
ORF1ab/nsp31251T1251TacCacA526B.10.000046
ORF1ab/nsp31251T1251TacCacT2626P.10.00041
ORF1ab/nsp31251T1251TacCacT2223AY.46.60.001589
ORF1ab/nsp31251T1251TacCacA123AY.46.60.000072
ORF1ab/nsp31251T1251TacCacT2122AY.1030.00013
ORF1ab/nsp31251T1251TacCacA122AY.1030.000006
ORF1ab/nsp31251T1251TacCacA1520B.1.1770.000198
ORF1ab/nsp31251T1251TacCacT520B.1.1770.000066
ORF1ab/nsp31251T1251TacCacT2020B.1.3460.026212
ORF1ab/nsp31251T1251TacCacT1018AY.430.000044
ORF1ab/nsp31251T1251TacCacA818AY.430.000035
ORF1ab/nsp31251T1251TacCacT1717AY.9.20.000624
ORF1ab/nsp31251T1251TacCacT1616AY.290.000252
ORF1ab/nsp31251T1251TacCacT1116B.1.177.770.007988
ORF1ab/nsp31251T1251TacCacA516B.1.177.770.003631
ORF1ab/nsp31251T1251TacCacT1515AY.60.000617
ORF1ab/nsp31251T1251TacCacT1414AY.30.000139
ORF1ab/nsp31251T1251TacCacA914B.1.10.000163
ORF1ab/nsp31251T1251TacCacT514B.1.10.000091
ORF1ab/nsp31251T1251TacCacA1313AY.80.007879
ORF1ab/nsp31251T1251TacCacT1313B.1.4270.000656
ORF1ab/nsp31251T1251TacCacT1013B.1.4290.000235
ORF1ab/nsp31251T1251TacCacA313B.1.4290.000071
ORF1ab/nsp31251T1251TacCacT1111P.1.10.003494
ORF1ab/nsp31251T1251TacCacT99AY.3.10.000767
ORF1ab/nsp31251T1251TacCacT99B.1.1.2160.008014
ORF1ab/nsp31251T1251TacCacT99B.1.1.2220.001836
ORF1ab/nsp31251T1251TacCacA68AY.330.000401
ORF1ab/nsp31251T1251TacCacT28AY.330.000134
ORF1ab/nsp31251T1251TacCacT77AY.740.00081
ORF1ab/nsp31251T1251TacCacT77B.1.2410.005682
ORF1ab/nsp31251T1251TacCacT77C.370.000812
ORF1ab/nsp31251T1251TacCacT66AY.360.000889
ORF1ab/nsp31251T1251TacCacT66B.1.617.10.000774
ORF1ab/nsp31251T1251TacCacT66B.1.621.10.003035
ORF1ab/nsp31251T1251TacCacT55AY.1190.000177
ORF1ab/nsp31251T1251TacCacT45AY.230.000279
ORF1ab/nsp31251T1251TacCacA15AY.230.00007
ORF1ab/nsp31251T1251TacCacT55AY.840.002187
ORF1ab/nsp31251T1251TacCacT55AY.98.10.000242
ORF1ab/nsp31251T1251TacCacT55B.1.1.3070.012658
ORF1ab/nsp31251T1251TacCacT55B.1.5250.000566
ORF1ab/nsp31251T1251TacCacT45B.1.5260.000094
ORF1ab/nsp31251T1251TacCacA15B.1.5260.000024
ORF1ab/nsp31251T1251TacCacT55B.1.5940.15625
ORF1ab/nsp31251T1251TacCacT44AY.340.000388
ORF1ab/nsp31251T1251TacCacT34AY.420.000121
ORF1ab/nsp31251T1251TacCacA14AY.420.00004
ORF1ab/nsp31251T1251TacCacT24B.1.1.2940.002532
ORF1ab/nsp31251T1251TacCacA24B.1.1.2940.002532
ORF1ab/nsp31251T1251TacCacT44B.1.1.4640.005891
ORF1ab/nsp31251T1251TacCacA44B.1.1.500.002716
ORF1ab/nsp31251T1251TacCacT44B.1.360.000584
ORF1ab/nsp31251T1251TacCacT44C.10.009569
ORF1ab/nsp31251T1251TacCacT33AY.1000.000138
ORF1ab/nsp31251T1251TacCacT33AY.210.005693
ORF1ab/nsp31251T1251TacCacT23AY.450.000243
ORF1ab/nsp31251T1251TacCacA13AY.450.000122
ORF1ab/nsp31251T1251TacCacT33AY.50.000062
ORF1ab/nsp31251T1251TacCacA33AY.540.000286
ORF1ab/nsp31251T1251TacCacT33AY.7.10.000338
ORF1ab/nsp31251T1251TacCacT33B.1.1.100.003344
ORF1ab/nsp31251T1251TacCacT33B.1.1.3480.002389
ORF1ab/nsp31251T1251TacCacT33B.1.1.5190.000119
ORF1ab/nsp31251T1251TacCacT33B.1.1.5280.014423
ORF1ab/nsp31251T1251TacCacT23B.1.177.600.000437
ORF1ab/nsp31251T1251TacCacA13B.1.177.600.000218
ORF1ab/nsp31251T1251TacCacT23B.1.2210.000142
ORF1ab/nsp31251T1251TacCacA13B.1.2210.000071
ORF1ab/nsp31251T1251TacCacA23B.1.3510.000059
ORF1ab/nsp31251T1251TacCacT13B.1.3510.00003
ORF1ab/nsp31251T1251TacCacT33B.1.36.80.003
ORF1ab/nsp31251T1251TacCacA33B.1.3620.004622
ORF1ab/nsp31251T1251TacCacT33B.1.5960.000261
ORF1ab/nsp31251T1251TacCacT33C.360.002732
ORF1ab/nsp31251T1251TacCacT33R.10.00027
ORF1ab/nsp31251T1251TacCacT22A.30.004193
ORF1ab/nsp31251T1251TacCacT22AY.1090.001479
ORF1ab/nsp31251T1251TacCacA22AY.1170.000169
ORF1ab/nsp31251T1251TacCacT22AY.140.000176
ORF1ab/nsp31251T1251TacCacT22AY.260.000057
ORF1ab/nsp31251T1251TacCacT22AY.29.10.000441
ORF1ab/nsp31251T1251TacCacT12AY.460.000104
ORF1ab/nsp31251T1251TacCacA12AY.460.000104
ORF1ab/nsp31251T1251TacCacT12AY.550.000917
ORF1ab/nsp31251T1251TacCacA12AY.550.000917
ORF1ab/nsp31251T1251TacCacA12AY.750.000056
ORF1ab/nsp31251T1251TacCacT12AY.750.000056
ORF1ab/nsp31251T1251TacCacT22B.1.1.2140.000111
ORF1ab/nsp31251T1251TacCacT22B.1.1.3170.000823
ORF1ab/nsp31251T1251TacCacT22B.1.466.20.000782
ORF1ab/nsp31251T1251TacCacT22B.1.5170.000854
ORF1ab/nsp31251T1251TacCacT22B.1.5640.000852
ORF1ab/nsp31251T1251TacCacT22B.1.5990.007299
ORF1ab/nsp31251T1251TacCacT22B.400.000729
ORF1ab/nsp31251T1251TacCacT22P.1.140.000096
ORF1ab/nsp31251T1251TacCacT22Q.30.00029
ORF1ab/nsp31251T1251TacCacT22Q.80.00033
ORF1ab/nsp31251T1251TacCacA110.055556
ORF1ab/nsp31251T1251TacCacT11A.2.5.10.004808
ORF1ab/nsp31251T1251TacCacA11AY.110.001339
ORF1ab/nsp31251T1251TacCacA11AY.1180.000063
ORF1ab/nsp31251T1251TacCacT11AY.120.10.000321
ORF1ab/nsp31251T1251TacCacA11AY.1210.000135
ORF1ab/nsp31251T1251TacCacT11AY.160.00038
ORF1ab/nsp31251T1251TacCacT11AY.190.00114
ORF1ab/nsp31251T1251TacCacT11AY.20.000356
ORF1ab/nsp31251T1251TacCacT11AY.300.000396
ORF1ab/nsp31251T1251TacCacA11AY.34.10.00051
ORF1ab/nsp31251T1251TacCacT11AY.4.50.000107
ORF1ab/nsp31251T1251TacCacT11AY.46.40.000165
ORF1ab/nsp31251T1251TacCacA11AY.470.000031
ORF1ab/nsp31251T1251TacCacT11AY.610.000105
ORF1ab/nsp31251T1251TacCacT11AY.620.000436
ORF1ab/nsp31251T1251TacCacT11AY.690.000187
ORF1ab/nsp31251T1251TacCacT11AY.70.000196
ORF1ab/nsp31251T1251TacCacT11AY.75.10.00018
ORF1ab/nsp31251T1251TacCacT11AY.9.10.000084
ORF1ab/nsp31251T1251TacCacT11AY.980.000079
ORF1ab/nsp31251T1251TacCacA11B0.000128
ORF1ab/nsp31251T1251TacCacA11B.1.1.250.000569
ORF1ab/nsp31251T1251TacCacT11B.1.1.3060.000438
ORF1ab/nsp31251T1251TacCacT11B.1.1.330.000421
ORF1ab/nsp31251T1251TacCacA11B.1.1.390.00051
ORF1ab/nsp31251T1251TacCacT11B.1.1.4480.002033
ORF1ab/nsp31251T1251TacCacT11B.1.1.510.001718
ORF1ab/nsp31251T1251TacCacT11B.1.1.5260.003546
ORF1ab/nsp31251T1251TacCacA11B.1.1.700.000341
ORF1ab/nsp31251T1251TacCacT11B.1.160.160.000929
ORF1ab/nsp31251T1251TacCacA11B.1.1640.014925
ORF1ab/nsp31251T1251TacCacA11B.1.177.350.000691
ORF1ab/nsp31251T1251TacCacT11B.1.177.40.000211
ORF1ab/nsp31251T1251TacCacA11B.1.177.560.000668
ORF1ab/nsp31251T1251TacCacT11B.1.177.580.001332
ORF1ab/nsp31251T1251TacCacT11B.1.177.70.000165
ORF1ab/nsp31251T1251TacCacT11B.1.177.810.000189
ORF1ab/nsp31251T1251TacCacT11B.1.177.820.000477
ORF1ab/nsp31251T1251TacCacT11B.1.1950.005025
ORF1ab/nsp31251T1251TacCacT11B.1.221.30.000833
ORF1ab/nsp31251T1251TacCacT11B.1.2340.000132
ORF1ab/nsp31251T1251TacCacT11B.1.258.140.00098
ORF1ab/nsp31251T1251TacCacT11B.1.36.100.004785
ORF1ab/nsp31251T1251TacCacT11B.1.4280.00102
ORF1ab/nsp31251T1251TacCacT11B.1.438.10.000107
ORF1ab/nsp31251T1251TacCacT11B.1.5650.00081
ORF1ab/nsp31251T1251TacCacT11B.1.6060.006024
ORF1ab/nsp31251T1251TacCacT11B.1.6280.000352
ORF1ab/nsp31251T1251TacCacT11B.1.6370.000073
ORF1ab/nsp31251T1251TacCacT11B.1.780.008547
ORF1ab/nsp31251T1251TacCacT11B.6.60.000889
ORF1ab/nsp31251T1251TacCacT11C.190.027027
ORF1ab/nsp31251T1251TacCacA11C.400.027778
ORF1ab/nsp31251T1251TacCacT11D.20.000075
ORF1ab/nsp31251T1251TacCacT11P.1.120.000484
ORF1ab/nsp31251T1251TacCacT11P.30.001595
ORF1ab/nsp31251T1251TacCacA11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.