CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = S848Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3848S848YS1666YnonsyntCttAt828215261-5263

Details of the mutation S848Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3848S848YtCttAt8282All0.000016
ORF1ab/nsp3848S848YtCttAt3232AY.40.00005
ORF1ab/nsp3848S848YtCttAt2323AY.4.50.002472
ORF1ab/nsp3848S848YtCttAt55AY.90.000338
ORF1ab/nsp3848S848YtCttAt44AY.80.002424
ORF1ab/nsp3848S848YtCttAt44B.10.000037
ORF1ab/nsp3848S848YtCttAt22AY.1200.000074
ORF1ab/nsp3848S848YtCttAt22AY.580.001815
ORF1ab/nsp3848S848YtCttAt22B.1.1.70.000002
ORF1ab/nsp3848S848YtCttAt11AY.170.008197
ORF1ab/nsp3848S848YtCttAt11AY.870.000833
ORF1ab/nsp3848S848YtCttAt11B.1.1.700.000341
ORF1ab/nsp3848S848YtCttAt11B.1.2430.00007
ORF1ab/nsp3848S848YtCttAt11B.1.4530.003236
ORF1ab/nsp3848S848YtCttAt11B.1.5260.000024
ORF1ab/nsp3848S848YtCttAt11B.1.5990.00365
ORF1ab/nsp3848S848YtCttAt11B.1.617.20.000004

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.