CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = S848C

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3848S848CS1666CnonsyntCttGt18170.9444445261-5263
ORF1ab/nsp3848S848CS1666CnonsyntCTtGC1810.05555565261-5263

Details of the mutation S848C within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3848S848CtCttGt1718All0.000003
ORF1ab/nsp3848S848CtCTtGC118All0
ORF1ab/nsp3848S848CtCttGt34B.1.1.70.000003
ORF1ab/nsp3848S848CtCTtGC14B.1.1.70.000001
ORF1ab/nsp3848S848CtCttGt33B.1.617.10.000387
ORF1ab/nsp3848S848CtCttGt11AY.1030.000006
ORF1ab/nsp3848S848CtCttGt11AY.1180.000063
ORF1ab/nsp3848S848CtCttGt11AY.200.000039
ORF1ab/nsp3848S848CtCttGt11AY.390.000025
ORF1ab/nsp3848S848CtCttGt11AY.430.000004
ORF1ab/nsp3848S848CtCttGt11AY.440.000006
ORF1ab/nsp3848S848CtCttGt11B.10.000009
ORF1ab/nsp3848S848CtCttGt11B.1.351.20.000303
ORF1ab/nsp3848S848CtCttGt11B.1.6370.000073
ORF1ab/nsp3848S848CtCttGt11B.60.00091
ORF1ab/nsp3848S848CtCttGt11P.1.130.000898

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.