CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = S697S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3697S697SS1515SsyntcCtcT207119630.9478514808-4810
ORF1ab/nsp3697S697SS1515SsyntcCtcA20711080.05214874808-4810

Details of the mutation S697S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3697S697StcCtcT19632071All0.000375
ORF1ab/nsp3697S697StcCtcA1082071All0.000021
ORF1ab/nsp3697S697StcCtcT12791295B.1.1.70.001145
ORF1ab/nsp3697S697StcCtcA161295B.1.1.70.000014
ORF1ab/nsp3697S697StcCtcT9192AY.40.000142
ORF1ab/nsp3697S697StcCtcA192AY.40.000002
ORF1ab/nsp3697S697StcCtcT4646B.1.1.580.247312
ORF1ab/nsp3697S697StcCtcT3145B.10.000284
ORF1ab/nsp3697S697StcCtcA1445B.10.000128
ORF1ab/nsp3697S697StcCtcT4343B.1.5250.004866
ORF1ab/nsp3697S697StcCtcT4040AY.1020.001061
ORF1ab/nsp3697S697StcCtcT2931B.1.617.20.000109
ORF1ab/nsp3697S697StcCtcA231B.1.617.20.000008
ORF1ab/nsp3697S697StcCtcT2930AY.430.000128
ORF1ab/nsp3697S697StcCtcA130AY.430.000004
ORF1ab/nsp3697S697StcCtcT2829AY.440.00017
ORF1ab/nsp3697S697StcCtcA129AY.440.000006
ORF1ab/nsp3697S697StcCtcT2626AY.50.000537
ORF1ab/nsp3697S697StcCtcT1620B.1.20.000141
ORF1ab/nsp3697S697StcCtcA420B.1.20.000035
ORF1ab/nsp3697S697StcCtcT1119AY.1030.000068
ORF1ab/nsp3697S697StcCtcA819AY.1030.00005
ORF1ab/nsp3697S697StcCtcT1618AY.390.000395
ORF1ab/nsp3697S697StcCtcA218AY.390.000049
ORF1ab/nsp3697S697StcCtcT1617P.10.000252
ORF1ab/nsp3697S697StcCtcA117P.10.000016
ORF1ab/nsp3697S697StcCtcT1016AY.250.00006
ORF1ab/nsp3697S697StcCtcA616AY.250.000036
ORF1ab/nsp3697S697StcCtcA1515B.1.2400.003233
ORF1ab/nsp3697S697StcCtcT1414B.1.1.2840.001504
ORF1ab/nsp3697S697StcCtcT1314B.1.1770.000171
ORF1ab/nsp3697S697StcCtcA114B.1.1770.000013
ORF1ab/nsp3697S697StcCtcT1212B.1.177.740.181818
ORF1ab/nsp3697S697StcCtcT1111B.1.5230.026961
ORF1ab/nsp3697S697StcCtcA510B.1.10.000091
ORF1ab/nsp3697S697StcCtcT510B.1.10.000091
ORF1ab/nsp3697S697StcCtcT1010B.1.4290.000235
ORF1ab/nsp3697S697StcCtcT79AY.30.00007
ORF1ab/nsp3697S697StcCtcA29AY.30.00002
ORF1ab/nsp3697S697StcCtcT77AY.1190.000247
ORF1ab/nsp3697S697StcCtcT77AY.420.000282
ORF1ab/nsp3697S697StcCtcT77B.1.2430.000487
ORF1ab/nsp3697S697StcCtcT66AY.46.40.000987
ORF1ab/nsp3697S697StcCtcT66AY.610.000629
ORF1ab/nsp3697S697StcCtcT66AZ.30.009119
ORF1ab/nsp3697S697StcCtcT66B.1.1.5190.000238
ORF1ab/nsp3697S697StcCtcT66B.1.3050.012903
ORF1ab/nsp3697S697StcCtcT66B.1.4080.02214
ORF1ab/nsp3697S697StcCtcA45AY.4.20.000087
ORF1ab/nsp3697S697StcCtcT15AY.4.20.000022
ORF1ab/nsp3697S697StcCtcT35B.1.5960.000261
ORF1ab/nsp3697S697StcCtcA25B.1.5960.000174
ORF1ab/nsp3697S697StcCtcT34AY.470.000093
ORF1ab/nsp3697S697StcCtcA14AY.470.000031
ORF1ab/nsp3697S697StcCtcT44B.1.1.280.001245
ORF1ab/nsp3697S697StcCtcT44B.1.2210.000284
ORF1ab/nsp3697S697StcCtcT44Q.80.00066
ORF1ab/nsp3697S697StcCtcT330.166667
ORF1ab/nsp3697S697StcCtcT33AY.230.000209
ORF1ab/nsp3697S697StcCtcT23AY.330.000134
ORF1ab/nsp3697S697StcCtcA13AY.330.000067
ORF1ab/nsp3697S697StcCtcT33AY.540.000286
ORF1ab/nsp3697S697StcCtcT33B.1.1.1270.1875
ORF1ab/nsp3697S697StcCtcA33B.1.1.2160.002671
ORF1ab/nsp3697S697StcCtcT33B.1.1600.000094
ORF1ab/nsp3697S697StcCtcT33B.1.2320.001612
ORF1ab/nsp3697S697StcCtcA33B.1.4280.003061
ORF1ab/nsp3697S697StcCtcA22A.210.00554
ORF1ab/nsp3697S697StcCtcT22AE.80.000978
ORF1ab/nsp3697S697StcCtcT22AV.10.010101
ORF1ab/nsp3697S697StcCtcT22AY.1000.000092
ORF1ab/nsp3697S697StcCtcT22AY.1100.000225
ORF1ab/nsp3697S697StcCtcT22AY.1180.000125
ORF1ab/nsp3697S697StcCtcT22AY.1200.000074
ORF1ab/nsp3697S697StcCtcT22AY.200.000078
ORF1ab/nsp3697S697StcCtcT22AY.260.000057
ORF1ab/nsp3697S697StcCtcT22AY.290.000032
ORF1ab/nsp3697S697StcCtcT22AY.5.30.000675
ORF1ab/nsp3697S697StcCtcT22AY.660.002139
ORF1ab/nsp3697S697StcCtcT22AY.750.000112
ORF1ab/nsp3697S697StcCtcT22AY.790.002421
ORF1ab/nsp3697S697StcCtcT22B.1.1.1410.004024
ORF1ab/nsp3697S697StcCtcT22B.1.1.2140.000111
ORF1ab/nsp3697S697StcCtcA22B.1.1.2220.000408
ORF1ab/nsp3697S697StcCtcA22B.1.1.250.001137
ORF1ab/nsp3697S697StcCtcT12B.1.2580.000067
ORF1ab/nsp3697S697StcCtcA12B.1.2580.000067
ORF1ab/nsp3697S697StcCtcT22B.1.258.30.00335
ORF1ab/nsp3697S697StcCtcT22B.1.3490.00143
ORF1ab/nsp3697S697StcCtcA12B.1.617.10.000129
ORF1ab/nsp3697S697StcCtcT12B.1.617.10.000129
ORF1ab/nsp3697S697StcCtcT22B.1.6210.000177
ORF1ab/nsp3697S697StcCtcT22C.90.060606
ORF1ab/nsp3697S697StcCtcT22P.1.10.000635
ORF1ab/nsp3697S697StcCtcT11AY.1010.00049
ORF1ab/nsp3697S697StcCtcT11AY.140.000088
ORF1ab/nsp3697S697StcCtcT11AY.16.10.00047
ORF1ab/nsp3697S697StcCtcT11AY.190.00114
ORF1ab/nsp3697S697StcCtcT11AY.270.000065
ORF1ab/nsp3697S697StcCtcT11AY.280.00189
ORF1ab/nsp3697S697StcCtcT11AY.370.000316
ORF1ab/nsp3697S697StcCtcT11AY.450.000122
ORF1ab/nsp3697S697StcCtcT11AY.460.000104
ORF1ab/nsp3697S697StcCtcT11AY.530.000288
ORF1ab/nsp3697S697StcCtcT11AY.590.00053
ORF1ab/nsp3697S697StcCtcT11AY.60.000041
ORF1ab/nsp3697S697StcCtcT11AY.770.001127
ORF1ab/nsp3697S697StcCtcA11AY.850.000427
ORF1ab/nsp3697S697StcCtcT11AY.9.10.000084
ORF1ab/nsp3697S697StcCtcT11AY.9.20.000037
ORF1ab/nsp3697S697StcCtcT11AY.920.000287
ORF1ab/nsp3697S697StcCtcT11AY.980.000079
ORF1ab/nsp3697S697StcCtcT11AY.99.20.000092
ORF1ab/nsp3697S697StcCtcT11B0.000128
ORF1ab/nsp3697S697StcCtcT11B.1.1.10.000327
ORF1ab/nsp3697S697StcCtcT11B.1.1.1700.001247
ORF1ab/nsp3697S697StcCtcT11B.1.1.2360.006897
ORF1ab/nsp3697S697StcCtcT11B.1.1.3010.001179
ORF1ab/nsp3697S697StcCtcT11B.1.1.3020.002075
ORF1ab/nsp3697S697StcCtcT11B.1.1.330.000421
ORF1ab/nsp3697S697StcCtcT11B.1.1.3480.000796
ORF1ab/nsp3697S697StcCtcT11B.1.1.3720.000689
ORF1ab/nsp3697S697StcCtcT11B.1.1310.008772
ORF1ab/nsp3697S697StcCtcA11B.1.177.530.002392
ORF1ab/nsp3697S697StcCtcT11B.1.177.750.001041
ORF1ab/nsp3697S697StcCtcT11B.1.177.860.000183
ORF1ab/nsp3697S697StcCtcT11B.1.2340.000132
ORF1ab/nsp3697S697StcCtcT11B.1.2790.000514
ORF1ab/nsp3697S697StcCtcT11B.1.3510.00003
ORF1ab/nsp3697S697StcCtcT11B.1.360.000146
ORF1ab/nsp3697S697StcCtcA11B.1.36.290.000517
ORF1ab/nsp3697S697StcCtcA11B.1.36.80.001
ORF1ab/nsp3697S697StcCtcA11B.1.3690.000285
ORF1ab/nsp3697S697StcCtcT11B.1.3910.001127
ORF1ab/nsp3697S697StcCtcA11B.1.4270.00005
ORF1ab/nsp3697S697StcCtcT11B.1.4700.001404
ORF1ab/nsp3697S697StcCtcT11B.1.4730.019231
ORF1ab/nsp3697S697StcCtcT11B.1.6370.000073
ORF1ab/nsp3697S697StcCtcT11B.4.40.018868
ORF1ab/nsp3697S697StcCtcT11C.180.002591
ORF1ab/nsp3697S697StcCtcA11C.370.000116
ORF1ab/nsp3697S697StcCtcT11P.1.70.000319
ORF1ab/nsp3697S697StcCtcT11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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