CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = S697F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3697S697FS1515FnonsyntCctTc127412730.9992154808-4810
ORF1ab/nsp3697S697FS1515FnonsyntCCtTT127410.0007849294808-4810

Details of the mutation S697F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3697S697FtCctTc12731274All0.000243
ORF1ab/nsp3697S697FtCCtTT11274All0
ORF1ab/nsp3697S697FtCctTc316316B.1.1.70.000283
ORF1ab/nsp3697S697FtCctTc216216B.1.6180.870968
ORF1ab/nsp3697S697FtCctTc8686B.1.1770.001132
ORF1ab/nsp3697S697FtCctTc8080B.1.20.000704
ORF1ab/nsp3697S697FtCctTc5252B.10.000476
ORF1ab/nsp3697S697FtCctTc3535AY.40.000054
ORF1ab/nsp3697S697FtCctTc2929AY.440.000177
ORF1ab/nsp3697S697FtCctTc2626AY.460.002706
ORF1ab/nsp3697S697FtCctTc2626B.1.1260.033163
ORF1ab/nsp3697S697FtCctTc2525B.1.617.20.000094
ORF1ab/nsp3697S697FtCctTc2424AY.430.000106
ORF1ab/nsp3697S697FtCctTc2323AY.250.000138
ORF1ab/nsp3697S697FtCctTc2222B.1.5250.00249
ORF1ab/nsp3697S697FtCctTc2121AY.200.000816
ORF1ab/nsp3697S697FtCctTc2020AY.1200.000744
ORF1ab/nsp3697S697FtCctTc1717AY.30.000169
ORF1ab/nsp3697S697FtCctTc1616B.1.4800.039801
ORF1ab/nsp3697S697FtCctTc1616C.370.001857
ORF1ab/nsp3697S697FtCctTc1515B.1.5820.00736
ORF1ab/nsp3697S697FtCctTc1212AY.1030.000075
ORF1ab/nsp3697S697FtCctTc1212B.1.177.810.002272
ORF1ab/nsp3697S697FtCctTc99AY.860.007469
ORF1ab/nsp3697S697FtCctTc99P.10.000142
ORF1ab/nsp3697S697FtCctTc88AY.360.001186
ORF1ab/nsp3697S697FtCctTc88B.1.10.000145
ORF1ab/nsp3697S697FtCctTc88Q.10.001011
ORF1ab/nsp3697S697FtCctTc77AY.1000.000322
ORF1ab/nsp3697S697FtCctTc77AY.750.000392
ORF1ab/nsp3697S697FtCctTc77B.1.2580.000466
ORF1ab/nsp3697S697FtCctTc66AY.1180.000376
ORF1ab/nsp3697S697FtCctTc66AY.670.002786
ORF1ab/nsp3697S697FtCctTc55B.1.1.390.002548
ORF1ab/nsp3697S697FtCctTc44AY.1210.000541
ORF1ab/nsp3697S697FtCctTc44AY.470.000124
ORF1ab/nsp3697S697FtCctTc44B.1.1.2940.005063
ORF1ab/nsp3697S697FtCctTc44B.1.2350.010076
ORF1ab/nsp3697S697FtCctTc44B.1.6280.001409
ORF1ab/nsp3697S697FtCctTc33AY.260.000085
ORF1ab/nsp3697S697FtCctTc33AY.4.20.000065
ORF1ab/nsp3697S697FtCctTc33AY.4.40.001227
ORF1ab/nsp3697S697FtCctTc33B.1.1.2220.000612
ORF1ab/nsp3697S697FtCctTc33B.1.3510.000089
ORF1ab/nsp3697S697FtCctTc120.055556
ORF1ab/nsp3697S697FtCCtTT120.055556
ORF1ab/nsp3697S697FtCctTc22AY.116.10.000623
ORF1ab/nsp3697S697FtCctTc22AY.120.000632
ORF1ab/nsp3697S697FtCctTc22AY.290.000032
ORF1ab/nsp3697S697FtCctTc22AY.50.000041
ORF1ab/nsp3697S697FtCctTc22AY.690.000373
ORF1ab/nsp3697S697FtCctTc22B.1.1.5190.000079
ORF1ab/nsp3697S697FtCctTc22B.1.1.700.000682
ORF1ab/nsp3697S697FtCctTc22B.1.1600.000062
ORF1ab/nsp3697S697FtCctTc22B.1.177.800.003824
ORF1ab/nsp3697S697FtCctTc22B.1.3990.003868
ORF1ab/nsp3697S697FtCctTc22B.1.5950.000522
ORF1ab/nsp3697S697FtCctTc22B.1.619.10.001283
ORF1ab/nsp3697S697FtCctTc22P.1.120.000968
ORF1ab/nsp3697S697FtCctTc11AY.1020.000027
ORF1ab/nsp3697S697FtCctTc11AY.1170.000085
ORF1ab/nsp3697S697FtCctTc11AY.1190.000035
ORF1ab/nsp3697S697FtCctTc11AY.140.000088
ORF1ab/nsp3697S697FtCctTc11AY.29.10.000221
ORF1ab/nsp3697S697FtCctTc11AY.390.000025
ORF1ab/nsp3697S697FtCctTc11AY.4.50.000107
ORF1ab/nsp3697S697FtCctTc11AY.420.00004
ORF1ab/nsp3697S697FtCctTc11AY.46.40.000165
ORF1ab/nsp3697S697FtCctTc11AY.46.60.000072
ORF1ab/nsp3697S697FtCctTc11AY.540.000095
ORF1ab/nsp3697S697FtCctTc11AY.590.00053
ORF1ab/nsp3697S697FtCctTc11AY.75.10.00018
ORF1ab/nsp3697S697FtCctTc11AY.790.001211
ORF1ab/nsp3697S697FtCctTc11AY.820.001357
ORF1ab/nsp3697S697FtCctTc11AY.980.000079
ORF1ab/nsp3697S697FtCctTc11AY.99.20.000092
ORF1ab/nsp3697S697FtCctTc11AZ.20.000821
ORF1ab/nsp3697S697FtCctTc11B0.000128
ORF1ab/nsp3697S697FtCctTc11B.1.1.2140.000055
ORF1ab/nsp3697S697FtCctTc11B.1.1.280.000311
ORF1ab/nsp3697S697FtCctTc11B.1.1.2980.000862
ORF1ab/nsp3697S697FtCctTc11B.1.1690.014925
ORF1ab/nsp3697S697FtCctTc11B.1.177.570.000281
ORF1ab/nsp3697S697FtCctTc11B.1.177.860.000183
ORF1ab/nsp3697S697FtCctTc11B.1.2340.000132
ORF1ab/nsp3697S697FtCctTc11B.1.2430.00007
ORF1ab/nsp3697S697FtCctTc11B.1.258.30.001675
ORF1ab/nsp3697S697FtCctTc11B.1.2800.007143
ORF1ab/nsp3697S697FtCctTc11B.1.36.170.000494
ORF1ab/nsp3697S697FtCctTc11B.1.3910.001127
ORF1ab/nsp3697S697FtCctTc11B.1.3960.000706
ORF1ab/nsp3697S697FtCctTc11B.1.428.30.012821
ORF1ab/nsp3697S697FtCctTc11B.1.4290.000024
ORF1ab/nsp3697S697FtCctTc11B.1.4480.002625
ORF1ab/nsp3697S697FtCctTc11B.1.466.20.000391
ORF1ab/nsp3697S697FtCctTc11B.1.5300.007143
ORF1ab/nsp3697S697FtCctTc11B.1.5960.000087
ORF1ab/nsp3697S697FtCctTc11B.1.6090.000479
ORF1ab/nsp3697S697FtCctTc11P.1.140.000048
ORF1ab/nsp3697S697FtCctTc11P.1.20.001156
ORF1ab/nsp3697S697FtCctTc11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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