CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = S674S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3674S674SS1492SsyntcTtcC134800.5970154739-4741
ORF1ab/nsp3674S674SS1492SsyntcTtcG134420.3134334739-4741
ORF1ab/nsp3674S674SS1492SsyntcTtcA134120.08955224739-4741

Details of the mutation S674S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3674S674StcTtcC80134All0.000015
ORF1ab/nsp3674S674StcTtcG42134All0.000008
ORF1ab/nsp3674S674StcTtcA12134All0.000002
ORF1ab/nsp3674S674StcTtcC3838B.1.10.000689
ORF1ab/nsp3674S674StcTtcG1616B.1.1.4240.727273
ORF1ab/nsp3674S674StcTtcA715B.1.1.70.000006
ORF1ab/nsp3674S674StcTtcC615B.1.1.70.000005
ORF1ab/nsp3674S674StcTtcG215B.1.1.70.000002
ORF1ab/nsp3674S674StcTtcC57B.1.617.20.000019
ORF1ab/nsp3674S674StcTtcG27B.1.617.20.000008
ORF1ab/nsp3674S674StcTtcC55AY.1030.000031
ORF1ab/nsp3674S674StcTtcC44AY.40.000006
ORF1ab/nsp3674S674StcTtcG44AY.440.000024
ORF1ab/nsp3674S674StcTtcG23AY.290.000032
ORF1ab/nsp3674S674StcTtcC13AY.290.000016
ORF1ab/nsp3674S674StcTtcG23AY.390.000049
ORF1ab/nsp3674S674StcTtcA13AY.390.000025
ORF1ab/nsp3674S674StcTtcC23B.1.20.000018
ORF1ab/nsp3674S674StcTtcA13B.1.20.000009
ORF1ab/nsp3674S674StcTtcG33B.1.4290.000071
ORF1ab/nsp3674S674StcTtcC22AY.730.001331
ORF1ab/nsp3674S674StcTtcC22B.10.000018
ORF1ab/nsp3674S674StcTtcG22B.1.1.2200.003717
ORF1ab/nsp3674S674StcTtcC22B.1.1770.000026
ORF1ab/nsp3674S674StcTtcA22B.1.4270.000101
ORF1ab/nsp3674S674StcTtcC12B.1.619.10.000641
ORF1ab/nsp3674S674StcTtcG12B.1.619.10.000641
ORF1ab/nsp3674S674StcTtcG11AM.40.003571
ORF1ab/nsp3674S674StcTtcG11AY.1040.001984
ORF1ab/nsp3674S674StcTtcC11AY.1200.000037
ORF1ab/nsp3674S674StcTtcC11AY.230.00007
ORF1ab/nsp3674S674StcTtcC11AY.250.000006
ORF1ab/nsp3674S674StcTtcC11AY.30.00001
ORF1ab/nsp3674S674StcTtcC11AY.430.000004
ORF1ab/nsp3674S674StcTtcC11AY.820.001357
ORF1ab/nsp3674S674StcTtcG11B.1.1.2140.000055
ORF1ab/nsp3674S674StcTtcC11B.1.1.390.00051
ORF1ab/nsp3674S674StcTtcG11B.1.1490.003425
ORF1ab/nsp3674S674StcTtcC11B.1.160.280.002924
ORF1ab/nsp3674S674StcTtcC11B.1.2410.000812
ORF1ab/nsp3674S674StcTtcC11B.1.2580.000067
ORF1ab/nsp3674S674StcTtcA11B.1.351.20.000303
ORF1ab/nsp3674S674StcTtcG11B.1.4970.000315
ORF1ab/nsp3674S674StcTtcG11B.1.5460.003704
ORF1ab/nsp3674S674StcTtcG11B.1.5650.00081
ORF1ab/nsp3674S674StcTtcG11B.1.6280.000352
ORF1ab/nsp3674S674StcTtcC11P.1.140.000048
ORF1ab/nsp3674S674StcTtcC11P.60.003145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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