CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = S371S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3371S371SS1189SsynagCagT6166110.9918833830-3832
ORF1ab/nsp3371S371SS1189SsynAGCTCA61620.003246753830-3832
ORF1ab/nsp3371S371SS1189SsynAGCTCT61620.003246753830-3832
ORF1ab/nsp3371S371SS1189SsynAGCTCG61610.001623383830-3832

Details of the mutation S371S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3371S371SagCagT611616All0.000117
ORF1ab/nsp3371S371SAGCTCT2616All0
ORF1ab/nsp3371S371SAGCTCA2616All0
ORF1ab/nsp3371S371SAGCTCG1616All0
ORF1ab/nsp3371S371SagCagT125125B.1.20.001101
ORF1ab/nsp3371S371SagCagT107112B.1.1.70.000096
ORF1ab/nsp3371S371SAGCTCA2112B.1.1.70.000002
ORF1ab/nsp3371S371SAGCTCT2112B.1.1.70.000002
ORF1ab/nsp3371S371SAGCTCG1112B.1.1.70.000001
ORF1ab/nsp3371S371SagCagT6363AY.40.000098
ORF1ab/nsp3371S371SagCagT4747AY.39.10.001862
ORF1ab/nsp3371S371SagCagT3333AY.440.000201
ORF1ab/nsp3371S371SagCagT1616B.1.617.20.00006
ORF1ab/nsp3371S371SagCagT1515AY.250.00009
ORF1ab/nsp3371S371SagCagT1414AY.370.004425
ORF1ab/nsp3371S371SagCagT1414B.1.1.2220.002856
ORF1ab/nsp3371S371SagCagT1414B.1.214.30.1
ORF1ab/nsp3371S371SagCagT1212B.10.00011
ORF1ab/nsp3371S371SagCagT99B.1.10.000163
ORF1ab/nsp3371S371SagCagT88AY.980.000632
ORF1ab/nsp3371S371SagCagT88B.1.1.2320.014519
ORF1ab/nsp3371S371SagCagT88B.1.1600.00025
ORF1ab/nsp3371S371SagCagT66AY.1030.000037
ORF1ab/nsp3371S371SagCagT55N.90.029762
ORF1ab/nsp3371S371SagCagT44C.36.30.002269
ORF1ab/nsp3371S371SagCagT33AY.260.000085
ORF1ab/nsp3371S371SagCagT33AY.30.00003
ORF1ab/nsp3371S371SagCagT33AY.430.000013
ORF1ab/nsp3371S371SagCagT33AY.470.000093
ORF1ab/nsp3371S371SagCagT33AY.540.000286
ORF1ab/nsp3371S371SagCagT33B.1.1770.00004
ORF1ab/nsp3371S371SagCagT33B.1.3510.000089
ORF1ab/nsp3371S371SagCagT33B.1.360.000438
ORF1ab/nsp3371S371SagCagT33B.1.4270.000151
ORF1ab/nsp3371S371SagCagT33P.10.000047
ORF1ab/nsp3371S371SagCagT22A.10.000564
ORF1ab/nsp3371S371SagCagT22AY.1180.000125
ORF1ab/nsp3371S371SagCagT22AY.1200.000074
ORF1ab/nsp3371S371SagCagT22AY.200.000078
ORF1ab/nsp3371S371SagCagT22AY.390.000049
ORF1ab/nsp3371S371SagCagT22AY.46.60.000144
ORF1ab/nsp3371S371SagCagT22AY.60.000082
ORF1ab/nsp3371S371SagCagT22AY.98.10.000097
ORF1ab/nsp3371S371SagCagT22B.1.2210.000142
ORF1ab/nsp3371S371SagCagT22B.1.36.180.00084
ORF1ab/nsp3371S371SagCagT22B.1.4290.000047
ORF1ab/nsp3371S371SagCagT22B.1.438.10.000215
ORF1ab/nsp3371S371SagCagT22B.1.466.20.000782
ORF1ab/nsp3371S371SagCagT22B.1.5260.000047
ORF1ab/nsp3371S371SagCagT22B.1.5650.001621
ORF1ab/nsp3371S371SagCagT110.055556
ORF1ab/nsp3371S371SagCagT11A.2.50.000499
ORF1ab/nsp3371S371SagCagT11AD.20.000219
ORF1ab/nsp3371S371SagCagT11AY.1000.000046
ORF1ab/nsp3371S371SagCagT11AY.1020.000027
ORF1ab/nsp3371S371SagCagT11AY.130.000161
ORF1ab/nsp3371S371SagCagT11AY.140.000088
ORF1ab/nsp3371S371SagCagT11AY.230.00007
ORF1ab/nsp3371S371SagCagT11AY.3.10.000085
ORF1ab/nsp3371S371SagCagT11AY.4.40.000409
ORF1ab/nsp3371S371SagCagT11AY.450.000122
ORF1ab/nsp3371S371SagCagT11AY.460.000104
ORF1ab/nsp3371S371SagCagT11AY.46.40.000165
ORF1ab/nsp3371S371SagCagT11AY.510.000909
ORF1ab/nsp3371S371SagCagT11AY.560.001605
ORF1ab/nsp3371S371SagCagT11AY.610.000105
ORF1ab/nsp3371S371SagCagT11AY.70.000196
ORF1ab/nsp3371S371SagCagT11AY.880.000884
ORF1ab/nsp3371S371SagCagT11B.1.1.2980.000862
ORF1ab/nsp3371S371SagCagT11B.1.1.3010.001179
ORF1ab/nsp3371S371SagCagT11B.1.1.3290.003846
ORF1ab/nsp3371S371SagCagT11B.1.1.3690.000446
ORF1ab/nsp3371S371SagCagT11B.1.1.5160.066667
ORF1ab/nsp3371S371SagCagT11B.1.1.5190.00004
ORF1ab/nsp3371S371SagCagT11B.1.160.200.008929
ORF1ab/nsp3371S371SagCagT11B.1.177.70.000165
ORF1ab/nsp3371S371SagCagT11B.1.177.810.000189
ORF1ab/nsp3371S371SagCagT11B.1.258.170.000104
ORF1ab/nsp3371S371SagCagT11B.1.351.20.000303
ORF1ab/nsp3371S371SagCagT11B.1.351.50.0006
ORF1ab/nsp3371S371SagCagT11B.1.36.290.000517
ORF1ab/nsp3371S371SagCagT11B.1.4000.000429
ORF1ab/nsp3371S371SagCagT11B.1.5250.000113
ORF1ab/nsp3371S371SagCagT11B.1.5400.009709
ORF1ab/nsp3371S371SagCagT11B.1.575.10.002439
ORF1ab/nsp3371S371SagCagT11B.1.617.10.000129
ORF1ab/nsp3371S371SagCagT11B.1.6370.000073
ORF1ab/nsp3371S371SagCagT11B.1.9.40.006135
ORF1ab/nsp3371S371SagCagT11B.60.00091
ORF1ab/nsp3371S371SagCagT11C.350.000774
ORF1ab/nsp3371S371SagCagT11P.1.140.000048
ORF1ab/nsp3371S371SagCagT11P.1.150.000232
ORF1ab/nsp3371S371SagCagT11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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