CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = S371R

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3371S371RS1189RnonsynagCagA100710.713830-3832
ORF1ab/nsp3371S371RS1189RnonsynAgcCgc100250.253830-3832
ORF1ab/nsp3371S371RS1189RnonsynagCagG10020.023830-3832
ORF1ab/nsp3371S371RS1189RnonsynAgCCgA10010.013830-3832
ORF1ab/nsp3371S371RS1189RnonsynAgCCgT10010.013830-3832

Details of the mutation S371R within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3371S371RagCagA71100All0.000014
ORF1ab/nsp3371S371RAgcCgc25100All0.000005
ORF1ab/nsp3371S371RagCagG2100All0
ORF1ab/nsp3371S371RAgCCgA1100All0
ORF1ab/nsp3371S371RAgCCgT1100All0
ORF1ab/nsp3371S371RagCagA1919B.1.110.30.013649
ORF1ab/nsp3371S371RAgcCgc718B.1.1.70.000006
ORF1ab/nsp3371S371RagCagA718B.1.1.70.000006
ORF1ab/nsp3371S371RagCagG218B.1.1.70.000002
ORF1ab/nsp3371S371RAgCCgA118B.1.1.70.000001
ORF1ab/nsp3371S371RAgCCgT118B.1.1.70.000001
ORF1ab/nsp3371S371RagCagA1010B.1.1.3680.030864
ORF1ab/nsp3371S371RagCagA66AY.39.10.000238
ORF1ab/nsp3371S371RagCagA56B.1.617.20.000019
ORF1ab/nsp3371S371RAgcCgc16B.1.617.20.000004
ORF1ab/nsp3371S371RAgcCgc34B.10.000027
ORF1ab/nsp3371S371RagCagA14B.10.000009
ORF1ab/nsp3371S371RagCagA44B.1.3510.000119
ORF1ab/nsp3371S371RagCagA33AY.1050.001929
ORF1ab/nsp3371S371RagCagA23AY.440.000012
ORF1ab/nsp3371S371RAgcCgc13AY.440.000006
ORF1ab/nsp3371S371RAgcCgc33B.1.36.80.003
ORF1ab/nsp3371S371RagCagA22AY.40.000003
ORF1ab/nsp3371S371RagCagA12B.1.10.000018
ORF1ab/nsp3371S371RAgcCgc12B.1.10.000018
ORF1ab/nsp3371S371RagCagA11AY.1020.000027
ORF1ab/nsp3371S371RAgcCgc11AY.1190.000035
ORF1ab/nsp3371S371RagCagA11AY.250.000006
ORF1ab/nsp3371S371RagCagA11AY.260.000028
ORF1ab/nsp3371S371RAgcCgc11AY.300.000396
ORF1ab/nsp3371S371RAgcCgc11AY.390.000025
ORF1ab/nsp3371S371RAgcCgc11AY.430.000004
ORF1ab/nsp3371S371RagCagA11AY.50.000021
ORF1ab/nsp3371S371RAgcCgc11AY.630.000387
ORF1ab/nsp3371S371RagCagA11AY.750.000056
ORF1ab/nsp3371S371RagCagA11AY.9.10.000084
ORF1ab/nsp3371S371RagCagA11AY.99.20.000092
ORF1ab/nsp3371S371RAgcCgc11B.1.1.2210.010101
ORF1ab/nsp3371S371RagCagA11B.1.177.230.003236
ORF1ab/nsp3371S371RAgcCgc11B.1.1840.058824
ORF1ab/nsp3371S371RagCagA11B.1.2210.000071
ORF1ab/nsp3371S371RAgcCgc11B.1.3110.000275
ORF1ab/nsp3371S371RAgcCgc11B.1.5250.000113
ORF1ab/nsp3371S371RagCagA11C.370.000116
ORF1ab/nsp3371S371RagCagA11P.10.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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