CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = S1265N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31265S1265NS2083NnonsynaGtaAt80380316512-6514

Details of the mutation S1265N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31265S1265NaGtaAt803803All0.000154
ORF1ab/nsp31265S1265NaGtaAt420420B.1.1600.013099
ORF1ab/nsp31265S1265NaGtaAt137137B.1.160.181
ORF1ab/nsp31265S1265NaGtaAt7070B.1.1.70.000063
ORF1ab/nsp31265S1265NaGtaAt5959AY.40.000092
ORF1ab/nsp31265S1265NaGtaAt4242B.1.1.3330.04521
ORF1ab/nsp31265S1265NaGtaAt1313B.10.000119
ORF1ab/nsp31265S1265NaGtaAt1212AY.140.001056
ORF1ab/nsp31265S1265NaGtaAt77B.1.2210.000497
ORF1ab/nsp31265S1265NaGtaAt55B.1.160.320.021459
ORF1ab/nsp31265S1265NaGtaAt33AY.1090.002219
ORF1ab/nsp31265S1265NaGtaAt33AY.9.20.00011
ORF1ab/nsp31265S1265NaGtaAt22AY.230.000139
ORF1ab/nsp31265S1265NaGtaAt22AY.390.000049
ORF1ab/nsp31265S1265NaGtaAt22AY.4.50.000215
ORF1ab/nsp31265S1265NaGtaAt22B.1.1770.000026
ORF1ab/nsp31265S1265NaGtaAt22B.1.2100.004264
ORF1ab/nsp31265S1265NaGtaAt11AY.1030.000006
ORF1ab/nsp31265S1265NaGtaAt11AY.1210.000135
ORF1ab/nsp31265S1265NaGtaAt11AY.130.000161
ORF1ab/nsp31265S1265NaGtaAt11AY.200.000039
ORF1ab/nsp31265S1265NaGtaAt11AY.260.000028
ORF1ab/nsp31265S1265NaGtaAt11AY.310.018519
ORF1ab/nsp31265S1265NaGtaAt11AY.340.000097
ORF1ab/nsp31265S1265NaGtaAt11AY.440.000006
ORF1ab/nsp31265S1265NaGtaAt11AY.470.000031
ORF1ab/nsp31265S1265NaGtaAt11AY.7.20.000559
ORF1ab/nsp31265S1265NaGtaAt11B.1.10.000018
ORF1ab/nsp31265S1265NaGtaAt11B.1.1.1760.000439
ORF1ab/nsp31265S1265NaGtaAt11B.1.1.2840.000107
ORF1ab/nsp31265S1265NaGtaAt11B.1.1.330.000421
ORF1ab/nsp31265S1265NaGtaAt11B.1.1.390.00051
ORF1ab/nsp31265S1265NaGtaAt11B.1.1.4090.002833
ORF1ab/nsp31265S1265NaGtaAt11B.1.177.170.000821
ORF1ab/nsp31265S1265NaGtaAt11B.1.4150.014286
ORF1ab/nsp31265S1265NaGtaAt11B.1.4990.00105
ORF1ab/nsp31265S1265NaGtaAt11B.1.617.20.000004
ORF1ab/nsp31265S1265NaGtaAt11B.1.6210.000089
ORF1ab/nsp31265S1265NaGtaAt11C.370.000116

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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