CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = S1206L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31206S1206LS2024LnonsyntCgtTg663966350.9993986335-6337
ORF1ab/nsp31206S1206LS2024LnonsyntCGtTA663920.000301256335-6337
ORF1ab/nsp31206S1206LS2024LnonsynTCgCTg663910.0001506256335-6337
ORF1ab/nsp31206S1206LS2024LnonsynTCGCTT663910.0001506256335-6337

Details of the mutation S1206L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31206S1206LtCgtTg66356639All0.001269
ORF1ab/nsp31206S1206LtCGtTA26639All0
ORF1ab/nsp31206S1206LTCGCTT16639All0
ORF1ab/nsp31206S1206LTCgCTg16639All0
ORF1ab/nsp31206S1206LtCgtTg16241624B.1.1.70.001454
ORF1ab/nsp31206S1206LtCgtTg874874AY.40.00136
ORF1ab/nsp31206S1206LtCgtTg395395AY.430.00175
ORF1ab/nsp31206S1206LtCgtTg316318B.1.20.002782
ORF1ab/nsp31206S1206LtCGtTA1318B.1.20.000009
ORF1ab/nsp31206S1206LTCgCTg1318B.1.20.000009
ORF1ab/nsp31206S1206LtCgtTg234234P.1.140.011185
ORF1ab/nsp31206S1206LtCgtTg215215B.1.617.20.00081
ORF1ab/nsp31206S1206LtCgtTg199199AY.30.001979
ORF1ab/nsp31206S1206LtCgtTg172172AY.250.001035
ORF1ab/nsp31206S1206LtCgtTg154154B.1.10.002794
ORF1ab/nsp31206S1206LtCgtTg153153AY.390.003781
ORF1ab/nsp31206S1206LtCgtTg136136P.10.002143
ORF1ab/nsp31206S1206LtCgtTg131131AY.440.000797
ORF1ab/nsp31206S1206LtCgtTg123123B.1.1770.00162
ORF1ab/nsp31206S1206LtCgtTg119119B.1.1600.003711
ORF1ab/nsp31206S1206LtCgtTg114114AY.470.003546
ORF1ab/nsp31206S1206LtCgtTg8080AY.1030.000497
ORF1ab/nsp31206S1206LtCgtTg7878B.1.5260.001833
ORF1ab/nsp31206S1206LtCgtTg7171B.10.00065
ORF1ab/nsp31206S1206LtCgtTg5656B.1.1.2220.011424
ORF1ab/nsp31206S1206LtCgtTg5050AY.1180.003132
ORF1ab/nsp31206S1206LtCgtTg4646B.1.177.810.008709
ORF1ab/nsp31206S1206LtCgtTg4343B.1.177.170.035304
ORF1ab/nsp31206S1206LtCgtTg4040B.1.1.5190.001588
ORF1ab/nsp31206S1206LtCgtTg4040B.1.4290.000941
ORF1ab/nsp31206S1206LtCgtTg3737B.1.2210.002628
ORF1ab/nsp31206S1206LtCgtTg3535B.1.3510.00104
ORF1ab/nsp31206S1206LtCgtTg3232B.1.416.10.05
ORF1ab/nsp31206S1206LtCgtTg3131AY.1190.001095
ORF1ab/nsp31206S1206LtCgtTg2727AY.260.000764
ORF1ab/nsp31206S1206LtCgtTg2626AY.1000.001196
ORF1ab/nsp31206S1206LtCgtTg2525B.1.4270.001262
ORF1ab/nsp31206S1206LtCgtTg2222AY.1020.000583
ORF1ab/nsp31206S1206LtCgtTg2222AY.290.000347
ORF1ab/nsp31206S1206LtCgtTg2222AY.420.000885
ORF1ab/nsp31206S1206LtCgtTg2222B.1.2430.001531
ORF1ab/nsp31206S1206LtCgtTg2121AY.1200.000781
ORF1ab/nsp31206S1206LtCgtTg2121B.1.1.1450.777778
ORF1ab/nsp31206S1206LtCgtTg2121B.1.1.3160.019426
ORF1ab/nsp31206S1206LtCgtTg1818AY.230.001255
ORF1ab/nsp31206S1206LtCgtTg1818AY.3.10.001535
ORF1ab/nsp31206S1206LtCgtTg1818AY.360.002668
ORF1ab/nsp31206S1206LtCgtTg1818AY.50.000372
ORF1ab/nsp31206S1206LtCgtTg1818B.1.1810.352941
ORF1ab/nsp31206S1206LtCgtTg1818B.1.6210.001593
ORF1ab/nsp31206S1206LtCgtTg1818C.370.002089
ORF1ab/nsp31206S1206LtCgtTg1717AY.330.001135
ORF1ab/nsp31206S1206LtCgtTg1515AY.1170.001268
ORF1ab/nsp31206S1206LtCgtTg1515AY.4.20.000325
ORF1ab/nsp31206S1206LtCgtTg1414AY.46.60.001011
ORF1ab/nsp31206S1206LtCgtTg1313AD.20.002847
ORF1ab/nsp31206S1206LtCgtTg1313B.1.2380.19403
ORF1ab/nsp31206S1206LtCgtTg1313Q.30.001885
ORF1ab/nsp31206S1206LtCgtTg1212B.1.1.280.003735
ORF1ab/nsp31206S1206LtCgtTg1212B.1.1.3170.00494
ORF1ab/nsp31206S1206LtCgtTg1212B.1.3770.054795
ORF1ab/nsp31206S1206LtCgtTg1212B.1.5640.005111
ORF1ab/nsp31206S1206LtCgtTg1111AY.39.10.000436
ORF1ab/nsp31206S1206LtCgtTg1111AY.670.005107
ORF1ab/nsp31206S1206LtCgtTg1111AY.98.10.000533
ORF1ab/nsp31206S1206LtCgtTg1010AY.4.2.10.00149
ORF1ab/nsp31206S1206LtCgtTg1010AY.790.012107
ORF1ab/nsp31206S1206LtCgtTg1010B.1.1.1760.004394
ORF1ab/nsp31206S1206LtCgtTg99AY.610.000943
ORF1ab/nsp31206S1206LtCgtTg99AY.9.20.000331
ORF1ab/nsp31206S1206LtCgtTg99B.1.2400.00194
ORF1ab/nsp31206S1206LtCgtTg99B.1.5960.000784
ORF1ab/nsp31206S1206LtCgtTg88B.1.177.210.000612
ORF1ab/nsp31206S1206LtCgtTg88B.1.6280.002819
ORF1ab/nsp31206S1206LtCgtTg77AY.200.000272
ORF1ab/nsp31206S1206LtCgtTg77AY.750.000392
ORF1ab/nsp31206S1206LtCgtTg77AY.99.20.000645
ORF1ab/nsp31206S1206LtCgtTg77B.1.177.330.011513
ORF1ab/nsp31206S1206LtCgtTg77B.1.3780.047945
ORF1ab/nsp31206S1206LtCgtTg77B.1.5250.000792
ORF1ab/nsp31206S1206LtCgtTg77B.1.6200.006623
ORF1ab/nsp31206S1206LtCgtTg66AY.1060.002009
ORF1ab/nsp31206S1206LtCgtTg66B.1.1.2140.000333
ORF1ab/nsp31206S1206LtCgtTg66B.1.466.20.002347
ORF1ab/nsp31206S1206LtCgtTg66R.10.00054
ORF1ab/nsp31206S1206LtCgtTg55AE.80.002445
ORF1ab/nsp31206S1206LtCgtTg45AY.1210.000541
ORF1ab/nsp31206S1206LtCGtTA15AY.1210.000135
ORF1ab/nsp31206S1206LtCgtTg55AY.140.00044
ORF1ab/nsp31206S1206LtCgtTg55AY.450.000608
ORF1ab/nsp31206S1206LtCgtTg55AY.5.40.001384
ORF1ab/nsp31206S1206LtCgtTg55AY.980.000395
ORF1ab/nsp31206S1206LtCgtTg55B.1.1.370.000964
ORF1ab/nsp31206S1206LtCgtTg55B.1.1.390.002548
ORF1ab/nsp31206S1206LtCgtTg55B.1.177.650.003327
ORF1ab/nsp31206S1206LtCgtTg55B.1.214.20.002998
ORF1ab/nsp31206S1206LtCgtTg55B.1.6370.000365
ORF1ab/nsp31206S1206LtCgtTg55P.1.120.00242
ORF1ab/nsp31206S1206LtCgtTg55Q.10.000632
ORF1ab/nsp31206S1206LtCgtTg44AY.120.001264
ORF1ab/nsp31206S1206LtCgtTg44AY.60.000165
ORF1ab/nsp31206S1206LtCgtTg44AY.75.10.000721
ORF1ab/nsp31206S1206LtCgtTg44AY.950.003044
ORF1ab/nsp31206S1206LtCgtTg44B0.000511
ORF1ab/nsp31206S1206LtCgtTg44B.1.1.5000.08
ORF1ab/nsp31206S1206LtCgtTg44B.1.177.400.020619
ORF1ab/nsp31206S1206LtCgtTg44B.1.2060.003263
ORF1ab/nsp31206S1206LtCgtTg44B.1.3690.001141
ORF1ab/nsp31206S1206LtCgtTg44B.1.3960.002823
ORF1ab/nsp31206S1206LtCgtTg33AY.130.000483
ORF1ab/nsp31206S1206LtCgtTg33AY.46.50.000595
ORF1ab/nsp31206S1206LtCgtTg33AY.480.001395
ORF1ab/nsp31206S1206LtCgtTg33AY.560.004815
ORF1ab/nsp31206S1206LtCgtTg33AY.640.001786
ORF1ab/nsp31206S1206LtCgtTg33AY.90.000203
ORF1ab/nsp31206S1206LtCgtTg33AY.9.10.000251
ORF1ab/nsp31206S1206LtCgtTg33B.1.1.1740.010135
ORF1ab/nsp31206S1206LtCgtTg33B.1.1.2550.009091
ORF1ab/nsp31206S1206LtCgtTg33B.1.1.2840.000322
ORF1ab/nsp31206S1206LtCgtTg33B.1.1.4870.01676
ORF1ab/nsp31206S1206LtCgtTg33B.1.177.860.00055
ORF1ab/nsp31206S1206LtCgtTg33B.1.2340.000396
ORF1ab/nsp31206S1206LtCgtTg33B.1.2580.0002
ORF1ab/nsp31206S1206LtCgtTg33B.1.3110.000824
ORF1ab/nsp31206S1206LtCgtTg33B.1.4970.000944
ORF1ab/nsp31206S1206LtCgtTg33B.1.5900.013636
ORF1ab/nsp31206S1206LtCgtTg33D.20.000225
ORF1ab/nsp31206S1206LtCgtTg33P.1.60.005837
ORF1ab/nsp31206S1206LtCgtTg33P.1.70.000958
ORF1ab/nsp31206S1206LtCgtTg33P.20.00056
ORF1ab/nsp31206S1206LtCgtTg22A.2.5.10.009615
ORF1ab/nsp31206S1206LtCgtTg22A.210.00554
ORF1ab/nsp31206S1206LtCgtTg22AY.1080.002205
ORF1ab/nsp31206S1206LtCgtTg22AY.240.000862
ORF1ab/nsp31206S1206LtCgtTg22AY.270.000129
ORF1ab/nsp31206S1206LtCgtTg22AY.29.10.000441
ORF1ab/nsp31206S1206LtCgtTg22AY.340.000194
ORF1ab/nsp31206S1206LtCgtTg22AY.34.10.00102
ORF1ab/nsp31206S1206LtCgtTg22AY.370.000632
ORF1ab/nsp31206S1206LtCgtTg22AY.4.50.000215
ORF1ab/nsp31206S1206LtCgtTg22AY.460.000208
ORF1ab/nsp31206S1206LtCgtTg22AY.590.001059
ORF1ab/nsp31206S1206LtCgtTg22AY.740.000231
ORF1ab/nsp31206S1206LtCgtTg22AY.840.000875
ORF1ab/nsp31206S1206LtCgtTg22AY.900.001369
ORF1ab/nsp31206S1206LtCgtTg22AY.920.000575
ORF1ab/nsp31206S1206LtCgtTg22B.1.1.2040.006079
ORF1ab/nsp31206S1206LtCgtTg22B.1.1.2160.001781
ORF1ab/nsp31206S1206LtCgtTg22B.1.1.3620.011236
ORF1ab/nsp31206S1206LtCgtTg22B.1.1.4190.014815
ORF1ab/nsp31206S1206LtCgtTg22B.1.1.4200.002012
ORF1ab/nsp31206S1206LtCgtTg22B.1.177.520.003515
ORF1ab/nsp31206S1206LtCgtTg22B.1.177.600.000437
ORF1ab/nsp31206S1206LtCgtTg22B.1.177.830.002963
ORF1ab/nsp31206S1206LtCgtTg22B.1.258.170.000208
ORF1ab/nsp31206S1206LtCgtTg22B.1.351.20.000605
ORF1ab/nsp31206S1206LtCgtTg22B.1.36.190.018519
ORF1ab/nsp31206S1206LtCgtTg22B.1.36.290.001035
ORF1ab/nsp31206S1206LtCgtTg22B.1.36.70.008
ORF1ab/nsp31206S1206LtCgtTg22B.1.4080.00738
ORF1ab/nsp31206S1206LtCgtTg22B.1.4360.002058
ORF1ab/nsp31206S1206LtCgtTg22B.1.4560.006536
ORF1ab/nsp31206S1206LtCgtTg22B.1.4660.046512
ORF1ab/nsp31206S1206LtCgtTg22B.1.4890.086957
ORF1ab/nsp31206S1206LtCgtTg22B.1.617.10.000258
ORF1ab/nsp31206S1206LtCgtTg22B.1.6270.00404
ORF1ab/nsp31206S1206LtCgtTg22C.130.051282
ORF1ab/nsp31206S1206LtCgtTg22P.1.10.000635
ORF1ab/nsp31206S1206LtCgtTg22P.1.170.000324
ORF1ab/nsp31206S1206LtCgtTg22P.1.80.009569
ORF1ab/nsp31206S1206LtCgtTg22P.70.008734
ORF1ab/nsp31206S1206LtCgtTg22Q.40.00091
ORF1ab/nsp31206S1206LtCgtTg11A.2.50.000499
ORF1ab/nsp31206S1206LtCgtTg11A.270.001656
ORF1ab/nsp31206S1206LtCgtTg11AJ.10.045455
ORF1ab/nsp31206S1206LtCgtTg11AU.10.001266
ORF1ab/nsp31206S1206LtCgtTg11AY.10.000396
ORF1ab/nsp31206S1206LtCgtTg11AY.1090.00074
ORF1ab/nsp31206S1206LtCgtTg11AY.1130.000142
ORF1ab/nsp31206S1206LtCgtTg11AY.1140.000231
ORF1ab/nsp31206S1206LtCgtTg11AY.120.10.000321
ORF1ab/nsp31206S1206LtCgtTg11AY.16.10.00047
ORF1ab/nsp31206S1206LtCgtTg11AY.320.000532
ORF1ab/nsp31206S1206LtCgtTg11AY.4.40.000409
ORF1ab/nsp31206S1206LtCgtTg11AY.46.20.000635
ORF1ab/nsp31206S1206LtCgtTg11AY.500.000799
ORF1ab/nsp31206S1206LtCgtTg11AY.540.000095
ORF1ab/nsp31206S1206LtCgtTg11AY.620.000436
ORF1ab/nsp31206S1206LtCgtTg11AY.70.000196
ORF1ab/nsp31206S1206LtCgtTg11AY.7.20.000559
ORF1ab/nsp31206S1206LtCgtTg11AY.700.000209
ORF1ab/nsp31206S1206LtCgtTg11AY.710.000475
ORF1ab/nsp31206S1206LtCgtTg11AY.730.000665
ORF1ab/nsp31206S1206LtCgtTg11AY.760.004831
ORF1ab/nsp31206S1206LtCgtTg11AY.910.00073
ORF1ab/nsp31206S1206LtCgtTg11AZ.10.000867
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.10.000327
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.100.001115
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.1690.018182
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.1980.001468
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.2070.001182
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.2170.003636
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.250.000569
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.2630.001558
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.2990.012195
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.3000.010753
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.3080.011765
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.3100.015152
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.3480.000796
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.3510.002793
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.3720.000689
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.3740.002375
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.3760.005952
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.3970.002252
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.4090.002833
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.4160.000905
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.4340.000349
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.4640.001473
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.510.001718
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.5180.006329
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.5230.001563
ORF1ab/nsp31206S1206LtCgtTg11B.1.1.950.019608
ORF1ab/nsp31206S1206LtCgtTg11B.1.160.220.006757
ORF1ab/nsp31206S1206LtCgtTg11B.1.160.290.004219
ORF1ab/nsp31206S1206LtCgtTg11B.1.177.190.001431
ORF1ab/nsp31206S1206LtCgtTg11B.1.177.200.001517
ORF1ab/nsp31206S1206LtCgtTg11B.1.177.260.006993
ORF1ab/nsp31206S1206LtCgtTg11B.1.177.320.00135
ORF1ab/nsp31206S1206LtCgtTg11B.1.177.40.000211
ORF1ab/nsp31206S1206LtCgtTg11B.1.177.770.000726
ORF1ab/nsp31206S1206LtCgtTg11B.1.177.850.005435
ORF1ab/nsp31206S1206LtCgtTg11B.1.258.240.010753
ORF1ab/nsp31206S1206LtCgtTg11B.1.2650.001271
ORF1ab/nsp31206S1206LtCgtTg11B.1.2890.00266
ORF1ab/nsp31206S1206LtCgtTg11B.1.3250.006897
ORF1ab/nsp31206S1206LtCgtTg11B.1.3460.001311
ORF1ab/nsp31206S1206LtCgtTg11B.1.360.000146
ORF1ab/nsp31206S1206LtCgtTg11B.1.36.80.001
ORF1ab/nsp31206S1206LtCgtTg11B.1.4000.000429
ORF1ab/nsp31206S1206LtCgtTg11B.1.4090.000781
ORF1ab/nsp31206S1206LtCgtTg11B.1.4110.003704
ORF1ab/nsp31206S1206LtCgtTg11B.1.4160.001269
ORF1ab/nsp31206S1206LtCgtTg11B.1.438.10.000107
ORF1ab/nsp31206S1206LtCgtTg11B.1.4480.002625
ORF1ab/nsp31206S1206LtCgtTg11B.1.4680.005714
ORF1ab/nsp31206S1206LtCgtTg11B.1.4700.001404
ORF1ab/nsp31206S1206LtCgtTg11B.1.5210.004975
ORF1ab/nsp31206S1206LtCgtTg11B.1.5750.000303
ORF1ab/nsp31206S1206LtCgtTg11B.1.5820.000491
ORF1ab/nsp31206S1206LtCgtTg11B.1.5860.010989
ORF1ab/nsp31206S1206LtCgtTg11B.1.5950.000261
ORF1ab/nsp31206S1206LtCgtTg11B.1.6090.000479
ORF1ab/nsp31206S1206LtCgtTg11B.1.621.10.000506
ORF1ab/nsp31206S1206LtCgtTg11B.1.6390.021739
ORF1ab/nsp31206S1206LtCgtTg11B.1.910.002075
ORF1ab/nsp31206S1206LtCgtTg11B.1.930.000934
ORF1ab/nsp31206S1206LtCgtTg11B.400.000364
ORF1ab/nsp31206S1206LtCgtTg11B.6.60.000889
ORF1ab/nsp31206S1206LtCgtTg11C.10.002392
ORF1ab/nsp31206S1206LtCgtTg11C.160.00106
ORF1ab/nsp31206S1206LtCgtTg11C.300.001727
ORF1ab/nsp31206S1206LTCGCTT11C.350.000774
ORF1ab/nsp31206S1206LtCgtTg11C.360.000911
ORF1ab/nsp31206S1206LtCgtTg11C.36.30.000567
ORF1ab/nsp31206S1206LtCgtTg11N.40.004255
ORF1ab/nsp31206S1206LtCgtTg11P.1.150.000232
ORF1ab/nsp31206S1206LtCgtTg11Q.20.000613
ORF1ab/nsp31206S1206LtCgtTg11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.