CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = Q172H

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3172Q172HQ990HnonsyncaAcaC32240.753233-3235
ORF1ab/nsp3172Q172HQ990HnonsyncaAcaT3280.253233-3235

Details of the mutation Q172H within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3172Q172HcaAcaC2432All0.000005
ORF1ab/nsp3172Q172HcaAcaT832All0.000002
ORF1ab/nsp3172Q172HcaAcaC1111B.1.1.70.00001
ORF1ab/nsp3172Q172HcaAcaT44P.10.000063
ORF1ab/nsp3172Q172HcaAcaT23B.1.617.20.000008
ORF1ab/nsp3172Q172HcaAcaC13B.1.617.20.000004
ORF1ab/nsp3172Q172HcaAcaC22AY.750.000112
ORF1ab/nsp3172Q172HcaAcaC22B.1.1.1410.004024
ORF1ab/nsp3172Q172HcaAcaC22B.1.1.4340.000697
ORF1ab/nsp3172Q172HcaAcaC11AY.1130.000142
ORF1ab/nsp3172Q172HcaAcaT11AY.16.10.00047
ORF1ab/nsp3172Q172HcaAcaC11AY.40.000002
ORF1ab/nsp3172Q172HcaAcaC11AY.440.000006
ORF1ab/nsp3172Q172HcaAcaC11B.10.000009
ORF1ab/nsp3172Q172HcaAcaC11B.1.1040.00369
ORF1ab/nsp3172Q172HcaAcaC11B.290.003509
ORF1ab/nsp3172Q172HcaAcaT11D.20.000075

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.