CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = P67L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp367P67LP885LnonsyncCacTa312631180.9974412918-2920
ORF1ab/nsp367P67LP885LnonsyncCAcTG312650.001599492918-2920
ORF1ab/nsp367P67LP885LnonsynCCATTG312620.0006397952918-2920
ORF1ab/nsp367P67LP885LnonsyncCAcTT312610.0003198982918-2920

Details of the mutation P67L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp367P67LcCacTa31183126All0.000596
ORF1ab/nsp367P67LcCAcTG53126All0.000001
ORF1ab/nsp367P67LCCATTG23126All0
ORF1ab/nsp367P67LcCAcTT13126All0
ORF1ab/nsp367P67LcCacTa934934AY.600.876173
ORF1ab/nsp367P67LcCacTa480480B.1.1.70.00043
ORF1ab/nsp367P67LcCacTa294294AY.50.006071
ORF1ab/nsp367P67LcCacTa178178B.1.2701
ORF1ab/nsp367P67LcCacTa139139B.1.20.001224
ORF1ab/nsp367P67LcCacTa117117B.1.617.20.000441
ORF1ab/nsp367P67LcCacTa102102AY.40.000159
ORF1ab/nsp367P67LcCacTa7777AY.250.000463
ORF1ab/nsp367P67LcCacTa7172AY.430.000315
ORF1ab/nsp367P67LcCAcTG172AY.430.000004
ORF1ab/nsp367P67LcCacTa3636B.10.00033
ORF1ab/nsp367P67LcCacTa3434AY.470.001058
ORF1ab/nsp367P67LcCacTa2828B.1.1770.000369
ORF1ab/nsp367P67LcCacTa2626AY.1030.000161
ORF1ab/nsp367P67LcCacTa2222AY.440.000134
ORF1ab/nsp367P67LcCacTa2122B.1.10.000381
ORF1ab/nsp367P67LcCAcTG122B.1.10.000018
ORF1ab/nsp367P67LcCacTa2121P.10.000331
ORF1ab/nsp367P67LcCacTa2020B.1.4290.000471
ORF1ab/nsp367P67LcCacTa1818AY.30.000179
ORF1ab/nsp367P67LcCacTa1818AY.4.20.00039
ORF1ab/nsp367P67LcCacTa1818B.1.2390.021978
ORF1ab/nsp367P67LcCacTa1818Q.20.011043
ORF1ab/nsp367P67LcCacTa1717AY.9.10.001423
ORF1ab/nsp367P67LcCacTa1616AY.290.000252
ORF1ab/nsp367P67LcCacTa1515B.1.5260.000353
ORF1ab/nsp367P67LcCacTa1414AY.230.000976
ORF1ab/nsp367P67LcCacTa1111AY.1200.000409
ORF1ab/nsp367P67LcCacTa1010B.1.1.500.006789
ORF1ab/nsp367P67LcCacTa1010B.1.2210.00071
ORF1ab/nsp367P67LcCacTa99AY.260.000255
ORF1ab/nsp367P67LcCacTa99B.1.1.390.004587
ORF1ab/nsp367P67LcCacTa99B.1.2580.000599
ORF1ab/nsp367P67LcCacTa88AY.940.003541
ORF1ab/nsp367P67LcCacTa88Q.40.003638
ORF1ab/nsp367P67LcCacTa77AY.420.000282
ORF1ab/nsp367P67LcCacTa77B.1.177.820.003341
ORF1ab/nsp367P67LcCacTa77B.1.36.270.005344
ORF1ab/nsp367P67LcCacTa77P.1.140.000335
ORF1ab/nsp367P67LcCacTa66AY.1020.000159
ORF1ab/nsp367P67LcCacTa66AY.1190.000212
ORF1ab/nsp367P67LcCacTa66AY.140.000528
ORF1ab/nsp367P67LcCacTa66AY.740.000694
ORF1ab/nsp367P67LcCacTa66B.1.160.290.025316
ORF1ab/nsp367P67LcCacTa66B.1.177.600.001311
ORF1ab/nsp367P67LcCacTa66B.1.5960.000523
ORF1ab/nsp367P67LcCacTa55AY.390.000124
ORF1ab/nsp367P67LcCacTa35AY.39.10.000119
ORF1ab/nsp367P67LcCAcTG25AY.39.10.000079
ORF1ab/nsp367P67LcCacTa55AY.4.50.000537
ORF1ab/nsp367P67LcCacTa55B.1.1.2770.003794
ORF1ab/nsp367P67LcCacTa44AY.1110.000733
ORF1ab/nsp367P67LcCacTa44AY.16.10.00188
ORF1ab/nsp367P67LcCacTa44AY.29.10.000882
ORF1ab/nsp367P67LcCacTa44AY.340.000388
ORF1ab/nsp367P67LcCacTa44AY.99.10.006211
ORF1ab/nsp367P67LcCacTa44AY.99.20.000369
ORF1ab/nsp367P67LcCacTa44B.1.1.10.001307
ORF1ab/nsp367P67LcCacTa44B.1.1600.000125
ORF1ab/nsp367P67LcCacTa44B.1.3510.000119
ORF1ab/nsp367P67LcCacTa44B.1.360.000584
ORF1ab/nsp367P67LcCacTa44B.1.4970.001259
ORF1ab/nsp367P67LcCacTa44B.1.6370.000292
ORF1ab/nsp367P67LcCacTa33AY.1130.000427
ORF1ab/nsp367P67LcCacTa33AY.330.0002
ORF1ab/nsp367P67LcCacTa33AY.460.000312
ORF1ab/nsp367P67LcCacTa33AY.480.001395
ORF1ab/nsp367P67LcCacTa33AY.650.001599
ORF1ab/nsp367P67LcCacTa23AY.670.000929
ORF1ab/nsp367P67LcCAcTG13AY.670.000464
ORF1ab/nsp367P67LcCacTa23AY.850.000854
ORF1ab/nsp367P67LcCAcTT13AY.850.000427
ORF1ab/nsp367P67LcCacTa33B.1.1.370.000579
ORF1ab/nsp367P67LcCacTa33B.1.2400.000647
ORF1ab/nsp367P67LcCacTa33P.20.00056
ORF1ab/nsp367P67LcCacTa33Q.50.050847
ORF1ab/nsp367P67LCCATTG220.111111
ORF1ab/nsp367P67LcCacTa22AY.1000.000092
ORF1ab/nsp367P67LcCacTa22AY.1080.002205
ORF1ab/nsp367P67LcCacTa22AY.1170.000169
ORF1ab/nsp367P67LcCacTa22AY.1210.000271
ORF1ab/nsp367P67LcCacTa22AY.130.000322
ORF1ab/nsp367P67LcCacTa22AY.210.003795
ORF1ab/nsp367P67LcCacTa22AY.380.000999
ORF1ab/nsp367P67LcCacTa22AY.46.60.000144
ORF1ab/nsp367P67LcCacTa22AY.590.001059
ORF1ab/nsp367P67LcCacTa22AY.610.00021
ORF1ab/nsp367P67LcCacTa22AY.640.00119
ORF1ab/nsp367P67LcCacTa22AY.7.20.001119
ORF1ab/nsp367P67LcCacTa22AY.750.000112
ORF1ab/nsp367P67LcCacTa22AY.75.10.000361
ORF1ab/nsp367P67LcCacTa22AY.80.001212
ORF1ab/nsp367P67LcCacTa22AY.870.001665
ORF1ab/nsp367P67LcCacTa22AY.9.20.000073
ORF1ab/nsp367P67LcCacTa22AY.980.000158
ORF1ab/nsp367P67LcCacTa22AY.98.10.000097
ORF1ab/nsp367P67LcCacTa22B.1.1.2160.001781
ORF1ab/nsp367P67LcCacTa22B.1.1.2220.000408
ORF1ab/nsp367P67LcCacTa22B.1.1.2260.011628
ORF1ab/nsp367P67LcCacTa22B.1.1.2510.015873
ORF1ab/nsp367P67LcCacTa22B.1.1.5190.000079
ORF1ab/nsp367P67LcCacTa22B.1.177.320.002699
ORF1ab/nsp367P67LcCacTa22B.1.177.350.001382
ORF1ab/nsp367P67LcCacTa22B.1.2340.000264
ORF1ab/nsp367P67LcCacTa22B.1.3620.003082
ORF1ab/nsp367P67LcCacTa22B.1.3910.002255
ORF1ab/nsp367P67LcCacTa22B.1.4270.000101
ORF1ab/nsp367P67LcCacTa22B.1.4740.003802
ORF1ab/nsp367P67LcCacTa22B.1.5380.016129
ORF1ab/nsp367P67LcCacTa22B.1.6090.000959
ORF1ab/nsp367P67LcCacTa22B.1.6210.000177
ORF1ab/nsp367P67LcCacTa22B.400.000729
ORF1ab/nsp367P67LcCacTa22N.60.014184
ORF1ab/nsp367P67LcCacTa22R.10.00018
ORF1ab/nsp367P67LcCacTa11A0.000387
ORF1ab/nsp367P67LcCacTa11A.2.50.000499
ORF1ab/nsp367P67LcCacTa11A.2.5.10.004808
ORF1ab/nsp367P67LcCacTa11AY.1100.000113
ORF1ab/nsp367P67LcCacTa11AY.300.000396
ORF1ab/nsp367P67LcCacTa11AY.360.000148
ORF1ab/nsp367P67LcCacTa11AY.520.000814
ORF1ab/nsp367P67LcCacTa11AY.540.000095
ORF1ab/nsp367P67LcCacTa11AY.550.000917
ORF1ab/nsp367P67LcCacTa11AY.60.000041
ORF1ab/nsp367P67LcCacTa11AY.7.10.000113
ORF1ab/nsp367P67LcCacTa11AY.770.001127
ORF1ab/nsp367P67LcCacTa11AY.880.000884
ORF1ab/nsp367P67LcCacTa11AY.930.000273
ORF1ab/nsp367P67LcCacTa11AY.990.001049
ORF1ab/nsp367P67LcCacTa11AZ.20.000821
ORF1ab/nsp367P67LcCacTa11B.1.1.100.001115
ORF1ab/nsp367P67LcCacTa11B.1.1.1480.008772
ORF1ab/nsp367P67LcCacTa11B.1.1.1610.003534
ORF1ab/nsp367P67LcCacTa11B.1.1.1700.001247
ORF1ab/nsp367P67LcCacTa11B.1.1.1740.003378
ORF1ab/nsp367P67LcCacTa11B.1.1.2140.000055
ORF1ab/nsp367P67LcCacTa11B.1.1.2440.015385
ORF1ab/nsp367P67LcCacTa11B.1.1.3060.000438
ORF1ab/nsp367P67LcCacTa11B.1.1.3070.002532
ORF1ab/nsp367P67LcCacTa11B.1.1.330.000421
ORF1ab/nsp367P67LcCacTa11B.1.1.3480.000796
ORF1ab/nsp367P67LcCacTa11B.1.1.3560.008547
ORF1ab/nsp367P67LcCacTa11B.1.1.3740.002375
ORF1ab/nsp367P67LcCacTa11B.1.1.4160.000905
ORF1ab/nsp367P67LcCacTa11B.1.1.4200.001006
ORF1ab/nsp367P67LcCacTa11B.1.1.4850.016667
ORF1ab/nsp367P67LcCacTa11B.1.1.5210.005348
ORF1ab/nsp367P67LcCacTa11B.1.1170.0125
ORF1ab/nsp367P67LcCacTa11B.1.177.40.000211
ORF1ab/nsp367P67LcCacTa11B.1.177.50.001242
ORF1ab/nsp367P67LcCacTa11B.1.177.530.002392
ORF1ab/nsp367P67LcCacTa11B.1.2220.001692
ORF1ab/nsp367P67LcCacTa11B.1.2410.000812
ORF1ab/nsp367P67LcCacTa11B.1.2430.00007
ORF1ab/nsp367P67LcCacTa11B.1.258.170.000104
ORF1ab/nsp367P67LcCacTa11B.1.3110.000275
ORF1ab/nsp367P67LcCacTa11B.1.3330.010526
ORF1ab/nsp367P67LcCacTa11B.1.36.290.000517
ORF1ab/nsp367P67LcCacTa11B.1.3610.001289
ORF1ab/nsp367P67LcCacTa11B.1.3690.000285
ORF1ab/nsp367P67LcCacTa11B.1.3810.007812
ORF1ab/nsp367P67LcCacTa11B.1.3890.001002
ORF1ab/nsp367P67LcCacTa11B.1.4030.003268
ORF1ab/nsp367P67LcCacTa11B.1.4130.004255
ORF1ab/nsp367P67LcCacTa11B.1.4220.000812
ORF1ab/nsp367P67LcCacTa11B.1.4260.001009
ORF1ab/nsp367P67LcCacTa11B.1.4560.003268
ORF1ab/nsp367P67LcCacTa11B.1.4620.007246
ORF1ab/nsp367P67LcCacTa11B.1.466.20.000391
ORF1ab/nsp367P67LcCacTa11B.1.5250.000113
ORF1ab/nsp367P67LcCacTa11B.1.5750.000303
ORF1ab/nsp367P67LcCacTa11B.1.5800.004065
ORF1ab/nsp367P67LcCacTa11B.1.619.10.000641
ORF1ab/nsp367P67LcCacTa11C.180.002591
ORF1ab/nsp367P67LcCacTa11C.280.04
ORF1ab/nsp367P67LcCacTa11C.36.30.000567
ORF1ab/nsp367P67LcCacTa11C.40.01
ORF1ab/nsp367P67LcCacTa11D.20.000075
ORF1ab/nsp367P67LcCacTa11P.1.130.000898
ORF1ab/nsp367P67LcCacTa11P.1.160.000374
ORF1ab/nsp367P67LcCacTa11P.1.20.001156
ORF1ab/nsp367P67LcCacTa11Q.10.000126
ORF1ab/nsp367P67LcCacTa11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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