CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = P389L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3389P389LP1207LnonsyncCtcTt234823450.9987223884-3886
ORF1ab/nsp3389P389LP1207LnonsyncCTcTA234820.0008517893884-3886
ORF1ab/nsp3389P389LP1207LnonsyncCTcTC234810.0004258943884-3886

Details of the mutation P389L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3389P389LcCtcTt23452348All0.000449
ORF1ab/nsp3389P389LcCTcTA22348All0
ORF1ab/nsp3389P389LcCTcTC12348All0
ORF1ab/nsp3389P389LcCtcTt335335B.1.1.70.0003
ORF1ab/nsp3389P389LcCtcTt297297B.1.4290.006988
ORF1ab/nsp3389P389LcCtcTt193193B.1.6120.511936
ORF1ab/nsp3389P389LcCtcTt162162B.1.10.002939
ORF1ab/nsp3389P389LcCtcTt112112AY.750.006275
ORF1ab/nsp3389P389LcCtcTt102102AY.250.000614
ORF1ab/nsp3389P389LcCtcTt8585B.1.4270.004292
ORF1ab/nsp3389P389LcCtcTt6969B.1.1.2650.217666
ORF1ab/nsp3389P389LcCtcTt6868AY.40.000106
ORF1ab/nsp3389P389LcCtcTt6565AY.1030.000404
ORF1ab/nsp3389P389LcCtcTt6363B.1.617.20.000237
ORF1ab/nsp3389P389LcCtcTt6161AY.50.00126
ORF1ab/nsp3389P389LcCtcTt5858B.1.2561
ORF1ab/nsp3389P389LcCtcTt4343B.10.000394
ORF1ab/nsp3389P389LcCtcTt3535B.1.351.30.030675
ORF1ab/nsp3389P389LcCtcTt3535Q.20.021472
ORF1ab/nsp3389P389LcCtcTt3232AY.430.000142
ORF1ab/nsp3389P389LcCtcTt3131B.1.20.000273
ORF1ab/nsp3389P389LcCtcTt2929B.1.5260.000682
ORF1ab/nsp3389P389LcCtcTt2727B.1.3510.000803
ORF1ab/nsp3389P389LcCtcTt2525AY.260.000708
ORF1ab/nsp3389P389LcCtcTt2323B.1.1600.000717
ORF1ab/nsp3389P389LcCtcTt2222AY.440.000134
ORF1ab/nsp3389P389LcCtcTt1818AY.690.00336
ORF1ab/nsp3389P389LcCtcTt1616B.1.360.002334
ORF1ab/nsp3389P389LcCtcTt1515AY.30.000149
ORF1ab/nsp3389P389LcCtcTt1414B.1.177.810.002651
ORF1ab/nsp3389P389LcCtcTt1313B.1.2580.000865
ORF1ab/nsp3389P389LcCtcTt1313P.10.000205
ORF1ab/nsp3389P389LcCtcTt1212AY.1210.001624
ORF1ab/nsp3389P389LcCtcTt1010AY.1000.00046
ORF1ab/nsp3389P389LcCtcTt1010B.1.5700.029412
ORF1ab/nsp3389P389LcCtcTt99AY.330.000601
ORF1ab/nsp3389P389LcCtcTt99P.20.00168
ORF1ab/nsp3389P389LcCtcTt88AY.1140.001849
ORF1ab/nsp3389P389LcCtcTt77AU.20.016949
ORF1ab/nsp3389P389LcCtcTt77B.1.1.2220.001428
ORF1ab/nsp3389P389LcCtcTt66AY.1200.000223
ORF1ab/nsp3389P389LcCtcTt66AZ.20.004926
ORF1ab/nsp3389P389LcCtcTt66B.1.5960.000523
ORF1ab/nsp3389P389LcCtcTt55AY.1190.000177
ORF1ab/nsp3389P389LcCtcTt55AY.60.000206
ORF1ab/nsp3389P389LcCtcTt55B.1.1.10.001633
ORF1ab/nsp3389P389LcCtcTt55B.1.1770.000066
ORF1ab/nsp3389P389LcCtcTt55B.1.6370.000365
ORF1ab/nsp3389P389LcCtcTt44AY.1020.000106
ORF1ab/nsp3389P389LcCtcTt44AY.1130.00057
ORF1ab/nsp3389P389LcCtcTt44AY.350.000932
ORF1ab/nsp3389P389LcCtcTt34AY.46.60.000217
ORF1ab/nsp3389P389LcCTcTA14AY.46.60.000072
ORF1ab/nsp3389P389LcCtcTt44AY.9.20.000147
ORF1ab/nsp3389P389LcCtcTt44B.1.1.330.001684
ORF1ab/nsp3389P389LcCtcTt44B.1.177.90.005326
ORF1ab/nsp3389P389LcCtcTt44B.1.466.20.001565
ORF1ab/nsp3389P389LcCtcTt44B.1.5440.024096
ORF1ab/nsp3389P389LcCtcTt33AY.230.000209
ORF1ab/nsp3389P389LcCtcTt33AY.270.000194
ORF1ab/nsp3389P389LcCtcTt33AY.290.000047
ORF1ab/nsp3389P389LcCtcTt33AY.390.000074
ORF1ab/nsp3389P389LcCtcTt33B.1.1.2030.050847
ORF1ab/nsp3389P389LcCtcTt33B.1.36.350.007812
ORF1ab/nsp3389P389LcCtcTt33B.1.4700.004213
ORF1ab/nsp3389P389LcCtcTt33D.20.000225
ORF1ab/nsp3389P389LcCTcTC120.055556
ORF1ab/nsp3389P389LcCtcTt120.055556
ORF1ab/nsp3389P389LcCtcTt22A.2.50.000998
ORF1ab/nsp3389P389LcCtcTt22AY.1180.000125
ORF1ab/nsp3389P389LcCtcTt22AY.240.000862
ORF1ab/nsp3389P389LcCtcTt22AY.4.20.000043
ORF1ab/nsp3389P389LcCtcTt22AY.420.00008
ORF1ab/nsp3389P389LcCtcTt22AY.470.000062
ORF1ab/nsp3389P389LcCtcTt22AY.540.000191
ORF1ab/nsp3389P389LcCtcTt22AY.670.000929
ORF1ab/nsp3389P389LcCtcTt22AY.740.000231
ORF1ab/nsp3389P389LcCtcTt22B.1.1.1630.015267
ORF1ab/nsp3389P389LcCtcTt22B.1.1.2370.010811
ORF1ab/nsp3389P389LcCtcTt22B.1.1.280.000622
ORF1ab/nsp3389P389LcCtcTt22B.1.1.370.000386
ORF1ab/nsp3389P389LcCtcTt22B.1.1.3970.004505
ORF1ab/nsp3389P389LcCtcTt22B.1.1.5190.000079
ORF1ab/nsp3389P389LcCtcTt22B.1.2140.007326
ORF1ab/nsp3389P389LcCtcTt22B.1.3110.000549
ORF1ab/nsp3389P389LcCtcTt22B.1.351.20.000605
ORF1ab/nsp3389P389LcCtcTt22B.1.5250.000226
ORF1ab/nsp3389P389LcCtcTt22B.1.5650.001621
ORF1ab/nsp3389P389LcCtcTt22B.1.6090.000959
ORF1ab/nsp3389P389LcCtcTt22B.1.617.10.000258
ORF1ab/nsp3389P389LcCtcTt22P.1.150.000465
ORF1ab/nsp3389P389LcCtcTt11A.20.000662
ORF1ab/nsp3389P389LcCtcTt11A.2.5.20.001572
ORF1ab/nsp3389P389LcCtcTt11A.210.00277
ORF1ab/nsp3389P389LcCtcTt11AY.100.00053
ORF1ab/nsp3389P389LcCtcTt11AY.1040.001984
ORF1ab/nsp3389P389LcCtcTt11AY.16.10.00047
ORF1ab/nsp3389P389LcCtcTt11AY.200.000039
ORF1ab/nsp3389P389LcCtcTt11AY.210.001898
ORF1ab/nsp3389P389LcCtcTt11AY.300.000396
ORF1ab/nsp3389P389LcCtcTt11AY.370.000316
ORF1ab/nsp3389P389LcCtcTt11AY.39.10.00004
ORF1ab/nsp3389P389LcCtcTt11AY.4.40.000409
ORF1ab/nsp3389P389LcCtcTt11AY.400.000964
ORF1ab/nsp3389P389LcCtcTt11AY.480.000465
ORF1ab/nsp3389P389LcCtcTt11AY.500.000799
ORF1ab/nsp3389P389LcCtcTt11AY.530.000288
ORF1ab/nsp3389P389LcCtcTt11AY.590.00053
ORF1ab/nsp3389P389LcCtcTt11AY.610.000105
ORF1ab/nsp3389P389LcCtcTt11AY.650.000533
ORF1ab/nsp3389P389LcCtcTt11AY.7.10.000113
ORF1ab/nsp3389P389LcCtcTt11AY.730.000665
ORF1ab/nsp3389P389LcCtcTt11AY.80.000606
ORF1ab/nsp3389P389LcCtcTt11AY.810.001992
ORF1ab/nsp3389P389LcCtcTt11AY.840.000437
ORF1ab/nsp3389P389LcCtcTt11AY.980.000079
ORF1ab/nsp3389P389LcCtcTt11AY.98.10.000048
ORF1ab/nsp3389P389LcCtcTt11B0.000128
ORF1ab/nsp3389P389LcCtcTt11B.1.1.1410.002012
ORF1ab/nsp3389P389LcCtcTt11B.1.1.1870.00885
ORF1ab/nsp3389P389LcCtcTt11B.1.1.1890.001513
ORF1ab/nsp3389P389LcCtcTt11B.1.1.2160.00089
ORF1ab/nsp3389P389LcCtcTt11B.1.1.250.000569
ORF1ab/nsp3389P389LcCtcTt11B.1.1.2790.001121
ORF1ab/nsp3389P389LcCtcTt11B.1.1.2840.000107
ORF1ab/nsp3389P389LcCtcTt11B.1.1.290.010309
ORF1ab/nsp3389P389LcCtcTt11B.1.1.3690.000446
ORF1ab/nsp3389P389LcCtcTt11B.1.1.4160.000905
ORF1ab/nsp3389P389LcCtcTt11B.1.1.4820.023256
ORF1ab/nsp3389P389LcCtcTt11B.1.1.5240.020833
ORF1ab/nsp3389P389LcCtcTt11B.1.110.30.000718
ORF1ab/nsp3389P389LcCtcTt11B.1.1110.001175
ORF1ab/nsp3389P389LcCtcTt11B.1.1390.000733
ORF1ab/nsp3389P389LcCtcTt11B.1.177.600.000218
ORF1ab/nsp3389P389LcCtcTt11B.1.177.870.000728
ORF1ab/nsp3389P389LcCtcTt11B.1.220.001318
ORF1ab/nsp3389P389LcCtcTt11B.1.2360.002053
ORF1ab/nsp3389P389LcCtcTt11B.1.2430.00007
ORF1ab/nsp3389P389LcCtcTt11B.1.3200.001245
ORF1ab/nsp3389P389LcCtcTt11B.1.3490.000715
ORF1ab/nsp3389P389LcCtcTt11B.1.36.10.00114
ORF1ab/nsp3389P389LcCtcTt11B.1.3690.000285
ORF1ab/nsp3389P389LcCTcTA11B.1.3770.004566
ORF1ab/nsp3389P389LcCtcTt11B.1.4260.001009
ORF1ab/nsp3389P389LcCtcTt11B.1.4970.000315
ORF1ab/nsp3389P389LcCtcTt11B.1.5760.000907
ORF1ab/nsp3389P389LcCtcTt11B.1.6210.000089
ORF1ab/nsp3389P389LcCtcTt11B.280.003279
ORF1ab/nsp3389P389LcCtcTt11C.370.000116
ORF1ab/nsp3389P389LcCtcTt11N.40.004255
ORF1ab/nsp3389P389LcCtcTt11P.1.70.000319
ORF1ab/nsp3389P389LcCtcTt11P.60.003145
ORF1ab/nsp3389P389LcCtcTt11Q.80.000165
ORF1ab/nsp3389P389LcCtcTt11R.10.00009
ORF1ab/nsp3389P389LcCtcTt11Z.10.00289

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.