CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = P340L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3340P340LP1158LnonsyncCtcTt838683800.9992853737-3739
ORF1ab/nsp3340P340LP1158LnonsyncCTcTC838630.0003577393737-3739
ORF1ab/nsp3340P340LP1158LnonsyncCTcTG838620.0002384933737-3739
ORF1ab/nsp3340P340LP1158LnonsyncCTcTA838610.0001192463737-3739

Details of the mutation P340L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3340P340LcCtcTt83808386All0.001603
ORF1ab/nsp3340P340LcCTcTC38386All0.000001
ORF1ab/nsp3340P340LcCTcTG28386All0
ORF1ab/nsp3340P340LcCTcTA18386All0
ORF1ab/nsp3340P340LcCtcTt767767B.1.1.390.390928
ORF1ab/nsp3340P340LcCtcTt763763B.1.5510.984516
ORF1ab/nsp3340P340LcCtcTt738739B.1.617.20.002779
ORF1ab/nsp3340P340LcCTcTC1739B.1.617.20.000004
ORF1ab/nsp3340P340LcCtcTt705705B.1.1.70.000631
ORF1ab/nsp3340P340LcCtcTt654654B.1.20.005759
ORF1ab/nsp3340P340LcCtcTt588588AY.1020.01559
ORF1ab/nsp3340P340LcCtcTt575575B.1.1.2840.061755
ORF1ab/nsp3340P340LcCtcTt435435AY.40.000677
ORF1ab/nsp3340P340LcCtcTt321321B.1.4270.01621
ORF1ab/nsp3340P340LcCtcTt160160B.10.001466
ORF1ab/nsp3340P340LcCtcTt155155AY.290.002445
ORF1ab/nsp3340P340LcCtcTt143143AY.250.00086
ORF1ab/nsp3340P340LcCtcTt131131AY.1030.000813
ORF1ab/nsp3340P340LcCtcTt9393AY.430.000412
ORF1ab/nsp3340P340LcCtcTt9393AY.930.025396
ORF1ab/nsp3340P340LcCtcTt9191AY.390.002249
ORF1ab/nsp3340P340LcCtcTt8282R.10.007381
ORF1ab/nsp3340P340LcCtcTt8181B.1.1770.001067
ORF1ab/nsp3340P340LcCtcTt7676D.20.005703
ORF1ab/nsp3340P340LcCtcTt7575B.1.1.2770.056904
ORF1ab/nsp3340P340LcCtcTt7272B.1.4290.001694
ORF1ab/nsp3340P340LcCtcTt7171AY.260.00201
ORF1ab/nsp3340P340LcCtcTt7171AY.440.000432
ORF1ab/nsp3340P340LcCtcTt6464B.1.1.500.043449
ORF1ab/nsp3340P340LcCtcTt5757B.1.1.3340.934426
ORF1ab/nsp3340P340LcCtcTt4848B.1.3490.03431
ORF1ab/nsp3340P340LcCtcTt4747B.1.5820.023062
ORF1ab/nsp3340P340LcCtcTt4646B.1.10.000834
ORF1ab/nsp3340P340LcCtcTt4545AY.470.0014
ORF1ab/nsp3340P340LcCtcTt4040AY.30.000398
ORF1ab/nsp3340P340LcCtcTt4040B.1.1600.001248
ORF1ab/nsp3340P340LcCtcTt3838B.1.177.210.002906
ORF1ab/nsp3340P340LcCtcTt3131AY.4.20.000672
ORF1ab/nsp3340P340LcCtcTt3030AY.450.003651
ORF1ab/nsp3340P340LcCtcTt2727B.1.1.370.005207
ORF1ab/nsp3340P340LcCtcTt2727B.1.2580.001797
ORF1ab/nsp3340P340LcCtcTt2525AY.540.002384
ORF1ab/nsp3340P340LcCtcTt2225P.10.000347
ORF1ab/nsp3340P340LcCTcTG225P.10.000032
ORF1ab/nsp3340P340LcCTcTA125P.10.000016
ORF1ab/nsp3340P340LcCtcTt2323B.1.2210.001634
ORF1ab/nsp3340P340LcCtcTt2222AY.1190.000777
ORF1ab/nsp3340P340LcCtcTt2222AY.460.00229
ORF1ab/nsp3340P340LcCtcTt2020B.1.5750.006068
ORF1ab/nsp3340P340LcCtcTt2020Q.30.002901
ORF1ab/nsp3340P340LcCtcTt1919B.1.1.3690.008478
ORF1ab/nsp3340P340LcCtcTt1919B.1.1.5190.000755
ORF1ab/nsp3340P340LcCtcTt1717AY.320.009052
ORF1ab/nsp3340P340LcCtcTt1515AY.1170.001268
ORF1ab/nsp3340P340LcCtcTt1515AY.34.10.007649
ORF1ab/nsp3340P340LcCtcTt1515B0.001917
ORF1ab/nsp3340P340LcCtcTt1515B.1.177.820.00716
ORF1ab/nsp3340P340LcCtcTt1414AY.190.015964
ORF1ab/nsp3340P340LcCtcTt1414AY.60.000576
ORF1ab/nsp3340P340LcCtcTt1313AY.1050.00836
ORF1ab/nsp3340P340LcCtcTt1212AY.5.30.004049
ORF1ab/nsp3340P340LcCtcTt1212B.1.1.2140.000665
ORF1ab/nsp3340P340LcCtcTt1111AY.1100.00124
ORF1ab/nsp3340P340LcCtcTt1111AY.90.000744
ORF1ab/nsp3340P340LcCtcTt1010B.1.1.2310.03096
ORF1ab/nsp3340P340LcCtcTt1010B.1.1.5260.035461
ORF1ab/nsp3340P340LcCtcTt1010B.1.3360.02439
ORF1ab/nsp3340P340LcCtcTt1010B.1.5230.02451
ORF1ab/nsp3340P340LcCtcTt1010P.20.001866
ORF1ab/nsp3340P340LcCtcTt99AY.330.000601
ORF1ab/nsp3340P340LcCtcTt99B.1.5260.000212
ORF1ab/nsp3340P340LcCtcTt88AY.1180.000501
ORF1ab/nsp3340P340LcCtcTt88AY.1200.000297
ORF1ab/nsp3340P340LcCtcTt88B.1.1.1350.037559
ORF1ab/nsp3340P340LcCtcTt88B.1.2430.000557
ORF1ab/nsp3340P340LcCtcTt88B.1.360.001167
ORF1ab/nsp3340P340LcCtcTt88B.1.6210.000708
ORF1ab/nsp3340P340LcCtcTt77AY.1000.000322
ORF1ab/nsp3340P340LcCtcTt77AY.116.10.00218
ORF1ab/nsp3340P340LcCtcTt77AY.200.000272
ORF1ab/nsp3340P340LcCtcTt77AY.50.000145
ORF1ab/nsp3340P340LcCtcTt77AY.550.006422
ORF1ab/nsp3340P340LcCtcTt77AY.980.000553
ORF1ab/nsp3340P340LcCtcTt77AY.98.10.000339
ORF1ab/nsp3340P340LcCtcTt77P.1.140.000335
ORF1ab/nsp3340P340LcCtcTt66AY.1130.000854
ORF1ab/nsp3340P340LcCtcTt66AY.610.000629
ORF1ab/nsp3340P340LcCtcTt66AY.7.10.000676
ORF1ab/nsp3340P340LcCtcTt66AY.720.008163
ORF1ab/nsp3340P340LcCtcTt66B.1.3510.000178
ORF1ab/nsp3340P340LcCtcTt66B.1.5640.002555
ORF1ab/nsp3340P340LcCtcTt66B.1.5760.00544
ORF1ab/nsp3340P340LcCtcTt66Q.10.000758
ORF1ab/nsp3340P340LcCtcTt350.166667
ORF1ab/nsp3340P340LcCTcTC250.111111
ORF1ab/nsp3340P340LcCtcTt55AY.340.000485
ORF1ab/nsp3340P340LcCtcTt55AY.46.60.000361
ORF1ab/nsp3340P340LcCtcTt55B.1.1.1280.035461
ORF1ab/nsp3340P340LcCtcTt55B.1.214.20.002998
ORF1ab/nsp3340P340LcCtcTt55B.1.2340.00066
ORF1ab/nsp3340P340LcCtcTt55B.1.36.290.002587
ORF1ab/nsp3340P340LcCtcTt55B.1.5090.004329
ORF1ab/nsp3340P340LcCtcTt55B.1.5880.00455
ORF1ab/nsp3340P340LcCtcTt55B.1.5960.000436
ORF1ab/nsp3340P340LcCtcTt55B.1.5970.023148
ORF1ab/nsp3340P340LcCtcTt55B.1.617.10.000645
ORF1ab/nsp3340P340LcCtcTt44AY.270.000259
ORF1ab/nsp3340P340LcCtcTt44AY.4.2.10.000596
ORF1ab/nsp3340P340LcCtcTt44AY.420.000161
ORF1ab/nsp3340P340LcCtcTt44AY.650.002132
ORF1ab/nsp3340P340LcCtcTt44AY.750.000224
ORF1ab/nsp3340P340LcCtcTt44AY.950.003044
ORF1ab/nsp3340P340LcCtcTt44B.1.1.2070.004728
ORF1ab/nsp3340P340LcCtcTt44B.1.177.440.002076
ORF1ab/nsp3340P340LcCtcTt44B.1.3980.011905
ORF1ab/nsp3340P340LcCtcTt44C.180.010363
ORF1ab/nsp3340P340LcCtcTt33AT.10.015385
ORF1ab/nsp3340P340LcCtcTt33AY.1210.000406
ORF1ab/nsp3340P340LcCtcTt33AY.230.000209
ORF1ab/nsp3340P340LcCtcTt33AY.4.40.001227
ORF1ab/nsp3340P340LcCtcTt33AY.4.50.000322
ORF1ab/nsp3340P340LcCtcTt33AY.730.001996
ORF1ab/nsp3340P340LcCtcTt33AY.740.000347
ORF1ab/nsp3340P340LcCtcTt33AY.790.003632
ORF1ab/nsp3340P340LcCtcTt33AY.9.20.00011
ORF1ab/nsp3340P340LcCtcTt33AY.99.20.000276
ORF1ab/nsp3340P340LcCtcTt33B.1.1.10.00098
ORF1ab/nsp3340P340LcCtcTt33B.1.1.250.001706
ORF1ab/nsp3340P340LcCtcTt33B.1.160.160.002788
ORF1ab/nsp3340P340LcCtcTt33B.1.160.320.012876
ORF1ab/nsp3340P340LcCtcTt33B.1.2320.001612
ORF1ab/nsp3340P340LcCtcTt33B.1.3690.000856
ORF1ab/nsp3340P340LcCtcTt33B.1.3960.002117
ORF1ab/nsp3340P340LcCtcTt33B.1.5950.000783
ORF1ab/nsp3340P340LcCtcTt33B.1.6180.012097
ORF1ab/nsp3340P340LcCtcTt33B.1.6230.001609
ORF1ab/nsp3340P340LcCtcTt33B.1.6370.000219
ORF1ab/nsp3340P340LcCtcTt33Q.80.000495
ORF1ab/nsp3340P340LcCtcTt22AL.10.025974
ORF1ab/nsp3340P340LcCtcTt22AY.1040.003968
ORF1ab/nsp3340P340LcCtcTt22AY.1060.00067
ORF1ab/nsp3340P340LcCtcTt22AY.1110.000366
ORF1ab/nsp3340P340LcCtcTt22AY.1140.000462
ORF1ab/nsp3340P340LcCtcTt22AY.1160.000574
ORF1ab/nsp3340P340LcCtcTt22AY.160.000759
ORF1ab/nsp3340P340LcCtcTt22AY.180.020202
ORF1ab/nsp3340P340LcCtcTt22AY.370.000632
ORF1ab/nsp3340P340LcCtcTt22AY.39.10.000079
ORF1ab/nsp3340P340LcCtcTt22AY.46.10.002053
ORF1ab/nsp3340P340LcCtcTt22AY.46.20.001271
ORF1ab/nsp3340P340LcCtcTt22AY.46.30.001867
ORF1ab/nsp3340P340LcCtcTt22AY.890.009804
ORF1ab/nsp3340P340LcCtcTt22AY.920.000575
ORF1ab/nsp3340P340LcCtcTt22B.1.1.1700.002494
ORF1ab/nsp3340P340LcCtcTt22B.1.1.3180.000604
ORF1ab/nsp3340P340LcCtcTt22B.1.1.330.000842
ORF1ab/nsp3340P340LcCtcTt22B.1.1.3720.001377
ORF1ab/nsp3340P340LcCtcTt22B.1.110.30.001437
ORF1ab/nsp3340P340LcCtcTt22B.1.160.120.012821
ORF1ab/nsp3340P340LcCtcTt22B.1.177.230.006472
ORF1ab/nsp3340P340LcCtcTt22B.1.177.430.002954
ORF1ab/nsp3340P340LcCtcTt22B.1.177.520.003515
ORF1ab/nsp3340P340LcCtcTt22B.1.177.810.000379
ORF1ab/nsp3340P340LcCtcTt22B.1.177.860.000367
ORF1ab/nsp3340P340LcCtcTt22B.1.177.870.001456
ORF1ab/nsp3340P340LcCtcTt22B.1.258.140.001961
ORF1ab/nsp3340P340LcCtcTt22B.1.3230.041667
ORF1ab/nsp3340P340LcCtcTt22B.1.36.180.00084
ORF1ab/nsp3340P340LcCtcTt22B.1.3670.001585
ORF1ab/nsp3340P340LcCtcTt22B.1.3990.003868
ORF1ab/nsp3340P340LcCtcTt22B.1.4000.000858
ORF1ab/nsp3340P340LcCtcTt22B.1.4040.002604
ORF1ab/nsp3340P340LcCtcTt22B.1.930.001867
ORF1ab/nsp3340P340LcCtcTt22B.4.70.020202
ORF1ab/nsp3340P340LcCtcTt22C.360.001821
ORF1ab/nsp3340P340LcCtcTt22C.36.30.001134
ORF1ab/nsp3340P340LcCtcTt22C.370.000232
ORF1ab/nsp3340P340LcCtcTt11AD.20.000219
ORF1ab/nsp3340P340LcCtcTt11AE.80.000489
ORF1ab/nsp3340P340LcCtcTt11AF.10.037037
ORF1ab/nsp3340P340LcCtcTt11AY.1080.001103
ORF1ab/nsp3340P340LcCtcTt11AY.120.000316
ORF1ab/nsp3340P340LcCtcTt11AY.240.000431
ORF1ab/nsp3340P340LcCtcTt11AY.29.10.000221
ORF1ab/nsp3340P340LcCtcTt11AY.380.000499
ORF1ab/nsp3340P340LcCtcTt11AY.400.000964
ORF1ab/nsp3340P340LcCtcTt11AY.46.40.000165
ORF1ab/nsp3340P340LcCtcTt11AY.480.000465
ORF1ab/nsp3340P340LcCtcTt11AY.580.000907
ORF1ab/nsp3340P340LcCtcTt11AY.70.000196
ORF1ab/nsp3340P340LcCtcTt11AY.75.10.00018
ORF1ab/nsp3340P340LcCtcTt11AY.780.001541
ORF1ab/nsp3340P340LcCtcTt11AY.840.000437
ORF1ab/nsp3340P340LcCtcTt11AY.850.000427
ORF1ab/nsp3340P340LcCtcTt11AY.860.00083
ORF1ab/nsp3340P340LcCtcTt11AY.880.000884
ORF1ab/nsp3340P340LcCtcTt11AY.900.000684
ORF1ab/nsp3340P340LcCtcTt11B.1.1.100.001115
ORF1ab/nsp3340P340LcCtcTt11B.1.1.1610.003534
ORF1ab/nsp3340P340LcCtcTt11B.1.1.1890.001513
ORF1ab/nsp3340P340LcCtcTt11B.1.1.2160.00089
ORF1ab/nsp3340P340LcCtcTt11B.1.1.270.00565
ORF1ab/nsp3340P340LcCtcTt11B.1.1.2820.011628
ORF1ab/nsp3340P340LcCtcTt11B.1.1.2940.001266
ORF1ab/nsp3340P340LcCtcTt11B.1.1.2980.000862
ORF1ab/nsp3340P340LcCtcTt11B.1.1.3050.003861
ORF1ab/nsp3340P340LcCtcTt11B.1.1.3160.000925
ORF1ab/nsp3340P340LcCtcTt11B.1.1.3170.000412
ORF1ab/nsp3340P340LcCtcTt11B.1.1.3260.001761
ORF1ab/nsp3340P340LcCtcTt11B.1.1.3480.000796
ORF1ab/nsp3340P340LcCtcTt11B.1.1.3800.009804
ORF1ab/nsp3340P340LcCtcTt11B.1.1.4070.041667
ORF1ab/nsp3340P340LcCtcTt11B.1.1.4320.001266
ORF1ab/nsp3340P340LcCtcTt11B.1.1.4420.018519
ORF1ab/nsp3340P340LcCtcTt11B.1.1.450.014085
ORF1ab/nsp3340P340LcCtcTt11B.1.1.4640.001473
ORF1ab/nsp3340P340LcCtcTt11B.1.1.5210.005348
ORF1ab/nsp3340P340LcCtcTt11B.1.1.5230.001563
ORF1ab/nsp3340P340LcCtcTt11B.1.1110.001175
ORF1ab/nsp3340P340LcCtcTt11B.1.1460.004237
ORF1ab/nsp3340P340LcCtcTt11B.1.1580.02381
ORF1ab/nsp3340P340LcCtcTt11B.1.160.110.005714
ORF1ab/nsp3340P340LcCtcTt11B.1.177.180.00116
ORF1ab/nsp3340P340LcCtcTt11B.1.177.40.000211
ORF1ab/nsp3340P340LcCtcTt11B.1.177.560.000668
ORF1ab/nsp3340P340LcCtcTt11B.1.177.620.001192
ORF1ab/nsp3340P340LcCtcTt11B.1.2100.002132
ORF1ab/nsp3340P340LcCtcTt11B.1.2220.001692
ORF1ab/nsp3340P340LcCtcTt11B.1.2390.001221
ORF1ab/nsp3340P340LcCtcTt11B.1.2400.000216
ORF1ab/nsp3340P340LcCtcTt11B.1.258.110.000396
ORF1ab/nsp3340P340LcCtcTt11B.1.258.170.000104
ORF1ab/nsp3340P340LcCtcTt11B.1.258.30.001675
ORF1ab/nsp3340P340LcCtcTt11B.1.258.70.001912
ORF1ab/nsp3340P340LcCtcTt11B.1.3110.000275
ORF1ab/nsp3340P340LcCtcTt11B.1.3320.003497
ORF1ab/nsp3340P340LcCtcTt11B.1.3800.006623
ORF1ab/nsp3340P340LcCtcTt11B.1.3890.001002
ORF1ab/nsp3340P340LcCtcTt11B.1.4090.000781
ORF1ab/nsp3340P340LcCtcTt11B.1.4220.000812
ORF1ab/nsp3340P340LcCtcTt11B.1.4560.003268
ORF1ab/nsp3340P340LcCtcTt11B.1.4680.005714
ORF1ab/nsp3340P340LcCtcTt11B.1.4700.001404
ORF1ab/nsp3340P340LcCtcTt11B.1.4730.019231
ORF1ab/nsp3340P340LcCtcTt11B.1.4970.000315
ORF1ab/nsp3340P340LcCtcTt11B.1.4990.00105
ORF1ab/nsp3340P340LcCtcTt11B.1.5250.000113
ORF1ab/nsp3340P340LcCtcTt11B.1.5770.000687
ORF1ab/nsp3340P340LcCtcTt11B.1.6090.000479
ORF1ab/nsp3340P340LcCtcTt11B.1.6280.000352
ORF1ab/nsp3340P340LcCtcTt11B.400.000364
ORF1ab/nsp3340P340LcCtcTt11B.60.00091
ORF1ab/nsp3340P340LcCtcTt11B.6.60.000889
ORF1ab/nsp3340P340LcCtcTt11B.610.005747
ORF1ab/nsp3340P340LcCtcTt11C.20.016129
ORF1ab/nsp3340P340LcCtcTt11C.350.000774
ORF1ab/nsp3340P340LcCtcTt11C.36.10.004149
ORF1ab/nsp3340P340LcCtcTt11P.1.100.000269
ORF1ab/nsp3340P340LcCtcTt11P.30.001595

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.