CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = P1867T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp3	1867	P1867T	P2685T	nonsyn	Ccc	Acc	5347	5346	0.999813	8318-8320
ORF1ab/nsp3	1867	P1867T	P2685T	nonsyn	CcC	AcT	5347	1	0.000187021	8318-8320

Details of the mutation P1867T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	5346	5347	All	0.001022
ORF1ab/nsp3	1867	P1867T	CcC	AcT	1	5347	All	0
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	875	875	AY.4.3	0.736532
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	839	839	B.1.1.7	0.000751
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	815	815	B.1.1.279	0.913677
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	302	302	AY.57	0.198163
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	280	280	AY.4	0.000436
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	212	213	B.1.617.2	0.000798
ORF1ab/nsp3	1867	P1867T	CcC	AcT	1	213	B.1.617.2	0.000004
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	197	197	AY.25	0.001185
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	148	148	AY.103	0.000919
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	133	133	AY.44	0.00081
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	94	94	P.1	0.001481
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	93	93	AY.43	0.000412
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	92	92	B.1.1	0.001669
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	83	83	B.1.2	0.000731
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	70	70	B.1.429	0.001647
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	56	56	B.1	0.000513
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	56	56	B.1.1.186	0.19244
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	53	53	Q.3	0.007687
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	50	50	B.1.351	0.001486
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	44	44	AY.100	0.002024
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	43	43	AY.3	0.000428
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	38	38	B.1.177.81	0.007194
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	38	38	R.1	0.00342
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	32	32	AY.102	0.000848
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	30	30	B.1.177.82	0.01432
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	29	29	B.1.258.17	0.003015
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	28	28	AY.29	0.000442
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	27	27	B.1.160	0.000842
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	25	25	AY.42	0.001006
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	24	24	B.1.177	0.000316
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	21	21	AY.20	0.000816
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	21	21	B.1.1.33	0.008838
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	21	21	B.1.1.425	0.954545
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	12	12	AY.24	0.005172
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	12	12	B.1.1.63	0.00463
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	12	12	B.1.243	0.000835
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	11	11	AY.23	0.000767
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	11	11	AY.47	0.000342
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	11	11	P.2	0.002053
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	10	10	AY.39	0.000247
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	10	10	AY.6	0.000411
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	10	10	AY.98.1	0.000484
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	9	9	AY.4.2	0.000195
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	9	9	B.1.526	0.000212
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	9	9	B.1.596	0.000784
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	8	8	AY.78	0.012327
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	8	8	B.1.1.50	0.005431
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	8	8	B.1.1.519	0.000318
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	7	7	AY.116.1	0.00218
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	7	7	AY.67	0.00325
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	7	7	AY.83	0.012069
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	7	7	B.1.36	0.001021
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	7	7	B.1.361	0.009021
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	6	6	AY.5	0.000124
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	6	6	AY.98	0.000474
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	6	6	B.1.1.222	0.001224
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	6	6	B.1.1.348	0.004777
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	6	6	B.1.240	0.001293
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	6	6	B.1.466.2	0.002347
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	6	6	C.37	0.000696
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	5	5	AY.26	0.000142
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	5	5	AY.45	0.000608
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	5	5	AY.46	0.00052
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	5	5	AY.61	0.000524
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	5	5	AY.84	0.002187
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	5	5	AY.85	0.002136
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	5	5	AY.99.2	0.000461
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	5	5	B.1.390	0.053191
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	4	4	AY.119	0.000141
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	4	4	AY.3.1	0.000341
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	4	4	AY.33	0.000267
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	4	4	AY.34	0.000388
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	4	4	B.1.221	0.000284
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	4	4	B.1.369	0.001141
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	4	4	B.1.561	0.001588
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	4	4	B.1.595	0.001044
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	4	4	B.1.621	0.000354
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	4	4	B.1.637	0.000292
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	4	4	C.35	0.003096
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	AY.12	0.000948
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	AY.120	0.000112
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	AY.121	0.000406
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	AY.30	0.001187
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	AY.32	0.001597
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	AY.36	0.000445
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	AY.4.2.1	0.000447
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	AY.46.6	0.000217
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	AY.60	0.002814
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	AY.75	0.000168
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	AY.91	0.002191
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	AZ.2	0.002463
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	B.1.160.24	0.013274
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	B.1.340	0.012876
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	B.1.36.29	0.001552
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	B.1.427	0.000151
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	N.5	0.0053
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	Q.2	0.00184
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	3	3	Q.8	0.000495
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	A.2.5	0.000998
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	AY.10	0.00106
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	AY.106	0.00067
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	AY.75.1	0.000361
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	AY.9.1	0.000167
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	B.1.1.25	0.001137
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	B.1.1.306	0.000877
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	B.1.1.523	0.003125
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	B.1.1.525	0.010929
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	B.1.177.33	0.003289
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	B.1.177.55	0.004662
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	B.1.177.73	0.001133
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	B.1.258	0.000133
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	B.1.258.4	0.006897
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	B.1.362	0.003082
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	B.1.525	0.000226
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	B.1.617.1	0.000258
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	N.6	0.014184
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	P.1.14	0.000096
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	P.1.15	0.000465
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	2	2	W.4	0.002703
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	A.19	0.009434
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	A.21	0.00277
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AH.3	0.003802
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AL.1	0.012987
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.101	0.00049
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.111	0.000183
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.114	0.000231
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.116	0.000287
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.118	0.000063
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.120.2	0.001285
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.16.1	0.00047
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.39.1	0.00004
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.4.4	0.000409
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.4.5	0.000107
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.40	0.000964
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.46.2	0.000635
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.46.3	0.000934
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.5.3	0.000337
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.51	0.000909
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.53	0.000288
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.54	0.000095
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.65	0.000533
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.69	0.000187
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.79	0.001211
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.9	0.000068
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.9.2	0.000037
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	AY.92	0.000287
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.10	0.001115
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.232	0.001815
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.277	0.000759
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.301	0.001179
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.311	0.000358
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.317	0.000412
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.320	0.018182
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.397	0.002252
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.416	0.000905
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.433	0.001425
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.448	0.002033
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.461	0.012048
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.1.528	0.004808
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.110	0.004525
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.110.3	0.000718
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.157	0.002985
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.160.26	0.002421
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.177.17	0.000821
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.177.5	0.001242
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.177.56	0.000668
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.177.60	0.000218
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.177.7	0.000165
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.177.77	0.000726
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.214	0.003663
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.221.4	0.004167
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.36.17	0.000494
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.36.31	0.001751
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.416	0.001269
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.426	0.001009
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.456	0.003268
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.459	0.004082
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.532	0.006211
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.588	0.00091
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.628	0.000352
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.1.631	0.003367
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	B.6	0.00091
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	C.14	0.004329
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	P.1.1	0.000318
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	P.1.10	0.000269
ORF1ab/nsp3	1867	P1867T	Ccc	Acc	1	1	Q.1	0.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.