CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = P153H

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3153P153HP971HnonsyncCtcAt23123113176-3178

Details of the mutation P153H within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3153P153HcCtcAt231231All0.000044
ORF1ab/nsp3153P153HcCtcAt2929B.1.617.20.000109
ORF1ab/nsp3153P153HcCtcAt2222B.1.1.70.00002
ORF1ab/nsp3153P153HcCtcAt1818AY.40.000028
ORF1ab/nsp3153P153HcCtcAt1616B.1.428.30.205128
ORF1ab/nsp3153P153HcCtcAt1313AY.1020.000345
ORF1ab/nsp3153P153HcCtcAt1010AY.440.000061
ORF1ab/nsp3153P153HcCtcAt99B.1.3510.000268
ORF1ab/nsp3153P153HcCtcAt99B.1.4290.000212
ORF1ab/nsp3153P153HcCtcAt88AY.430.000035
ORF1ab/nsp3153P153HcCtcAt88B.10.000073
ORF1ab/nsp3153P153HcCtcAt77AY.30.00007
ORF1ab/nsp3153P153HcCtcAt66AY.1030.000037
ORF1ab/nsp3153P153HcCtcAt66B.1.20.000053
ORF1ab/nsp3153P153HcCtcAt66B.1.2430.000418
ORF1ab/nsp3153P153HcCtcAt44AY.390.000099
ORF1ab/nsp3153P153HcCtcAt44B.1.1770.000053
ORF1ab/nsp3153P153HcCtcAt33B.1.4270.000151
ORF1ab/nsp3153P153HcCtcAt33P.10.000047
ORF1ab/nsp3153P153HcCtcAt22AY.1180.000125
ORF1ab/nsp3153P153HcCtcAt22AY.200.000078
ORF1ab/nsp3153P153HcCtcAt22AY.330.000134
ORF1ab/nsp3153P153HcCtcAt22AY.340.000194
ORF1ab/nsp3153P153HcCtcAt22AY.50.000041
ORF1ab/nsp3153P153HcCtcAt22AY.750.000112
ORF1ab/nsp3153P153HcCtcAt22AY.940.000885
ORF1ab/nsp3153P153HcCtcAt22B.1.10.000036
ORF1ab/nsp3153P153HcCtcAt22B.1.1.5190.000079
ORF1ab/nsp3153P153HcCtcAt22B.1.5950.000522
ORF1ab/nsp3153P153HcCtcAt22B.1.621.10.001012
ORF1ab/nsp3153P153HcCtcAt22N.50.003534
ORF1ab/nsp3153P153HcCtcAt22P.1.170.000324
ORF1ab/nsp3153P153HcCtcAt11AY.1200.000037
ORF1ab/nsp3153P153HcCtcAt11AY.250.000006
ORF1ab/nsp3153P153HcCtcAt11AY.260.000028
ORF1ab/nsp3153P153HcCtcAt11AY.400.000964
ORF1ab/nsp3153P153HcCtcAt11AY.460.000104
ORF1ab/nsp3153P153HcCtcAt11AY.46.50.000198
ORF1ab/nsp3153P153HcCtcAt11AY.470.000031
ORF1ab/nsp3153P153HcCtcAt11AY.530.000288
ORF1ab/nsp3153P153HcCtcAt11AY.540.000095
ORF1ab/nsp3153P153HcCtcAt11AY.9.20.000037
ORF1ab/nsp3153P153HcCtcAt11AY.980.000079
ORF1ab/nsp3153P153HcCtcAt11B0.000128
ORF1ab/nsp3153P153HcCtcAt11B.1.1.3800.009804
ORF1ab/nsp3153P153HcCtcAt11B.1.1.4090.002833
ORF1ab/nsp3153P153HcCtcAt11B.1.1.610.008772
ORF1ab/nsp3153P153HcCtcAt11B.1.2210.000071
ORF1ab/nsp3153P153HcCtcAt11B.1.3620.001541
ORF1ab/nsp3153P153HcCtcAt11B.1.4590.004082
ORF1ab/nsp3153P153HcCtcAt11B.1.617.10.000129
ORF1ab/nsp3153P153HcCtcAt11B.30.000831
ORF1ab/nsp3153P153HcCtcAt11B.6.60.000889
ORF1ab/nsp3153P153HcCtcAt11C.350.000774
ORF1ab/nsp3153P153HcCtcAt11C.360.000911
ORF1ab/nsp3153P153HcCtcAt11D.20.000075

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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