CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = P1326S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31326P1326SP2144SnonsynCctTct112511200.9955566695-6697
ORF1ab/nsp31326P1326SP2144SnonsynCCtAGt112520.001777786695-6697
ORF1ab/nsp31326P1326SP2144SnonsynCcTTcC112520.001777786695-6697
ORF1ab/nsp31326P1326SP2144SnonsynCcTTcG112510.0008888896695-6697

Details of the mutation P1326S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31326P1326SCctTct11201125All0.000214
ORF1ab/nsp31326P1326SCCtAGt21125All0
ORF1ab/nsp31326P1326SCcTTcC21125All0
ORF1ab/nsp31326P1326SCcTTcG11125All0
ORF1ab/nsp31326P1326SCctTct209210B.1.1.70.000187
ORF1ab/nsp31326P1326SCcTTcC1210B.1.1.70.000001
ORF1ab/nsp31326P1326SCctTct193193AY.430.000855
ORF1ab/nsp31326P1326SCctTct153153AY.40.000238
ORF1ab/nsp31326P1326SCctTct9090B.1.177.90.11984
ORF1ab/nsp31326P1326SCctTct6969AY.4.20.001497
ORF1ab/nsp31326P1326SCctTct5959B.1.20.00052
ORF1ab/nsp31326P1326SCctTct4343AY.440.000262
ORF1ab/nsp31326P1326SCctTct3840B.1.617.20.000143
ORF1ab/nsp31326P1326SCcTTcG140B.1.617.20.000004
ORF1ab/nsp31326P1326SCCtAGt140B.1.617.20.000004
ORF1ab/nsp31326P1326SCctTct1515B.1.177.770.010893
ORF1ab/nsp31326P1326SCctTct1414AY.390.000346
ORF1ab/nsp31326P1326SCctTct1414B.10.000128
ORF1ab/nsp31326P1326SCctTct1212AY.1020.000318
ORF1ab/nsp31326P1326SCctTct1212AY.1030.000075
ORF1ab/nsp31326P1326SCctTct1212C.370.001393
ORF1ab/nsp31326P1326SCctTct99B.1.1.370.001736
ORF1ab/nsp31326P1326SCctTct88AY.1160.002294
ORF1ab/nsp31326P1326SCctTct88AY.370.002528
ORF1ab/nsp31326P1326SCctTct88AY.470.000249
ORF1ab/nsp31326P1326SCctTct88AY.690.001493
ORF1ab/nsp31326P1326SCctTct88B.1.10.000145
ORF1ab/nsp31326P1326SCctTct88B.1.1.5190.000318
ORF1ab/nsp31326P1326SCctTct77AY.30.00007
ORF1ab/nsp31326P1326SCctTct66AY.1190.000212
ORF1ab/nsp31326P1326SCctTct66B0.000767
ORF1ab/nsp31326P1326SCctTct55AY.230.000349
ORF1ab/nsp31326P1326SCctTct55B.1.258.170.00052
ORF1ab/nsp31326P1326SCctTct55P.10.000079
ORF1ab/nsp31326P1326SCctTct44AY.360.000593
ORF1ab/nsp31326P1326SCctTct44B.1.1.1530.004381
ORF1ab/nsp31326P1326SCctTct33AY.1170.000254
ORF1ab/nsp31326P1326SCctTct33AY.200.000117
ORF1ab/nsp31326P1326SCctTct33AY.250.000018
ORF1ab/nsp31326P1326SCctTct33AY.550.002752
ORF1ab/nsp31326P1326SCctTct33B.1.1600.000094
ORF1ab/nsp31326P1326SCctTct33B.1.360.000438
ORF1ab/nsp31326P1326SCctTct33B.1.5410.013274
ORF1ab/nsp31326P1326SCctTct33B.1.6370.000219
ORF1ab/nsp31326P1326SCctTct120.055556
ORF1ab/nsp31326P1326SCcTTcC120.055556
ORF1ab/nsp31326P1326SCctTct22A.2.50.000998
ORF1ab/nsp31326P1326SCctTct22AY.1040.003968
ORF1ab/nsp31326P1326SCctTct22AY.1060.00067
ORF1ab/nsp31326P1326SCctTct22AY.290.000032
ORF1ab/nsp31326P1326SCctTct22AY.590.001059
ORF1ab/nsp31326P1326SCctTct22AY.60.000082
ORF1ab/nsp31326P1326SCctTct22B.1.1.10.000653
ORF1ab/nsp31326P1326SCctTct22B.1.2210.000142
ORF1ab/nsp31326P1326SCctTct22B.1.4290.000047
ORF1ab/nsp31326P1326SCctTct22B.1.5400.019417
ORF1ab/nsp31326P1326SCctTct22B.1.5960.000174
ORF1ab/nsp31326P1326SCctTct11A.210.00277
ORF1ab/nsp31326P1326SCctTct11AY.1000.000046
ORF1ab/nsp31326P1326SCctTct11AY.1050.000643
ORF1ab/nsp31326P1326SCCtAGt11AY.1130.000142
ORF1ab/nsp31326P1326SCctTct11AY.1180.000063
ORF1ab/nsp31326P1326SCctTct11AY.16.10.00047
ORF1ab/nsp31326P1326SCctTct11AY.270.000065
ORF1ab/nsp31326P1326SCctTct11AY.39.10.00004
ORF1ab/nsp31326P1326SCctTct11AY.4.30.000842
ORF1ab/nsp31326P1326SCctTct11AY.460.000104
ORF1ab/nsp31326P1326SCctTct11AY.50.000021
ORF1ab/nsp31326P1326SCctTct11AY.740.000116
ORF1ab/nsp31326P1326SCctTct11AY.750.000056
ORF1ab/nsp31326P1326SCctTct11AY.9.10.000084
ORF1ab/nsp31326P1326SCctTct11AY.99.20.000092
ORF1ab/nsp31326P1326SCctTct11AZ.20.000821
ORF1ab/nsp31326P1326SCctTct11B.1.1.1740.003378
ORF1ab/nsp31326P1326SCctTct11B.1.1.2140.000055
ORF1ab/nsp31326P1326SCctTct11B.1.1.270.00565
ORF1ab/nsp31326P1326SCctTct11B.1.1.3180.000302
ORF1ab/nsp31326P1326SCctTct11B.1.1.4340.000349
ORF1ab/nsp31326P1326SCctTct11B.1.1.630.000386
ORF1ab/nsp31326P1326SCctTct11B.1.1770.000013
ORF1ab/nsp31326P1326SCctTct11B.1.177.420.000894
ORF1ab/nsp31326P1326SCctTct11B.1.177.750.001041
ORF1ab/nsp31326P1326SCctTct11B.1.2060.000816
ORF1ab/nsp31326P1326SCctTct11B.1.2400.000216
ORF1ab/nsp31326P1326SCctTct11B.1.2430.00007
ORF1ab/nsp31326P1326SCctTct11B.1.2580.000067
ORF1ab/nsp31326P1326SCctTct11B.1.3510.00003
ORF1ab/nsp31326P1326SCctTct11B.1.36.290.000517
ORF1ab/nsp31326P1326SCctTct11B.1.3950.007042
ORF1ab/nsp31326P1326SCctTct11B.1.4530.003236
ORF1ab/nsp31326P1326SCctTct11B.1.4560.003268
ORF1ab/nsp31326P1326SCctTct11B.1.5250.000113
ORF1ab/nsp31326P1326SCctTct11B.1.5260.000024
ORF1ab/nsp31326P1326SCctTct11B.1.5600.00463
ORF1ab/nsp31326P1326SCctTct11B.1.621.10.000506
ORF1ab/nsp31326P1326SCctTct11P.1.140.000048
ORF1ab/nsp31326P1326SCctTct11P.20.000187
ORF1ab/nsp31326P1326SCctTct11Q.10.000126
ORF1ab/nsp31326P1326SCctTct11Q.40.000455

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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