CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = P1326P

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31326P1326PP2144PsynccTccC1471100.7482996695-6697
ORF1ab/nsp31326P1326PP2144PsynccTccG147300.2040826695-6697
ORF1ab/nsp31326P1326PP2144PsynccTccA14770.0476196695-6697

Details of the mutation P1326P within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31326P1326PccTccC110147All0.000021
ORF1ab/nsp31326P1326PccTccG30147All0.000006
ORF1ab/nsp31326P1326PccTccA7147All0.000001
ORF1ab/nsp31326P1326PccTccC2323AY.440.00014
ORF1ab/nsp31326P1326PccTccC1414B.1.1.70.000013
ORF1ab/nsp31326P1326PccTccG711B.1.617.20.000026
ORF1ab/nsp31326P1326PccTccC411B.1.617.20.000015
ORF1ab/nsp31326P1326PccTccG711P.10.00011
ORF1ab/nsp31326P1326PccTccC311P.10.000047
ORF1ab/nsp31326P1326PccTccA111P.10.000016
ORF1ab/nsp31326P1326PccTccC99AY.40.000014
ORF1ab/nsp31326P1326PccTccC66B.1.4270.000303
ORF1ab/nsp31326P1326PccTccC55B.10.000046
ORF1ab/nsp31326P1326PccTccC44AY.1000.000184
ORF1ab/nsp31326P1326PccTccA24AY.250.000012
ORF1ab/nsp31326P1326PccTccG14AY.250.000006
ORF1ab/nsp31326P1326PccTccC14AY.250.000006
ORF1ab/nsp31326P1326PccTccC44B.1.1.2140.000222
ORF1ab/nsp31326P1326PccTccG23AY.1020.000053
ORF1ab/nsp31326P1326PccTccC13AY.1020.000027
ORF1ab/nsp31326P1326PccTccC23AY.200.000078
ORF1ab/nsp31326P1326PccTccA13AY.200.000039
ORF1ab/nsp31326P1326PccTccG33AY.46.60.000217
ORF1ab/nsp31326P1326PccTccC23B.1.20.000018
ORF1ab/nsp31326P1326PccTccA13B.1.20.000009
ORF1ab/nsp31326P1326PccTccG22AY.390.000049
ORF1ab/nsp31326P1326PccTccC22AY.39.10.000079
ORF1ab/nsp31326P1326PccTccC22AY.430.000009
ORF1ab/nsp31326P1326PccTccC22AY.470.000062
ORF1ab/nsp31326P1326PccTccC22B.1.10.000036
ORF1ab/nsp31326P1326PccTccC22B.1.1770.000026
ORF1ab/nsp31326P1326PccTccC22Q.30.00029
ORF1ab/nsp31326P1326PccTccC22R.10.00018
ORF1ab/nsp31326P1326PccTccC110.055556
ORF1ab/nsp31326P1326PccTccG11AY.1030.000006
ORF1ab/nsp31326P1326PccTccG11AY.1210.000135
ORF1ab/nsp31326P1326PccTccC11AY.190.00114
ORF1ab/nsp31326P1326PccTccC11AY.23.10.000417
ORF1ab/nsp31326P1326PccTccC11AY.30.00001
ORF1ab/nsp31326P1326PccTccC11AY.340.000097
ORF1ab/nsp31326P1326PccTccG11AY.4.50.000107
ORF1ab/nsp31326P1326PccTccG11AY.450.000122
ORF1ab/nsp31326P1326PccTccA11AY.50.000021
ORF1ab/nsp31326P1326PccTccC11AY.700.000209
ORF1ab/nsp31326P1326PccTccG11AY.780.001541
ORF1ab/nsp31326P1326PccTccC11AY.9.20.000037
ORF1ab/nsp31326P1326PccTccG11B0.000128
ORF1ab/nsp31326P1326PccTccC11B.1.1.370.000193
ORF1ab/nsp31326P1326PccTccC11B.1.1.4320.001266
ORF1ab/nsp31326P1326PccTccC11B.1.1600.000031
ORF1ab/nsp31326P1326PccTccA11B.1.177.730.000566
ORF1ab/nsp31326P1326PccTccC11B.1.1890.004292
ORF1ab/nsp31326P1326PccTccC11B.1.2430.00007
ORF1ab/nsp31326P1326PccTccG11B.1.2580.000067
ORF1ab/nsp31326P1326PccTccC11B.1.36.360.000602
ORF1ab/nsp31326P1326PccTccC11B.1.3750.00082
ORF1ab/nsp31326P1326PccTccC11B.1.4290.000024
ORF1ab/nsp31326P1326PccTccC11B.1.5240.001406
ORF1ab/nsp31326P1326PccTccC11B.1.5820.000491
ORF1ab/nsp31326P1326PccTccG11P.1.150.000232
ORF1ab/nsp31326P1326PccTccC11P.1.170.000162

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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