CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = P1326L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31326P1326LP2144LnonsyncCtcTt2440244016695-6697

Details of the mutation P1326L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31326P1326LcCtcTt24402440All0.000467
ORF1ab/nsp31326P1326LcCtcTt797797B.1.1.70.000713
ORF1ab/nsp31326P1326LcCtcTt194194B.1.2430.013499
ORF1ab/nsp31326P1326LcCtcTt155155B.1.2580.010315
ORF1ab/nsp31326P1326LcCtcTt144144B.10.001319
ORF1ab/nsp31326P1326LcCtcTt121121B.101
ORF1ab/nsp31326P1326LcCtcTt106106B.1.10.001923
ORF1ab/nsp31326P1326LcCtcTt7575B.1.1.2840.008055
ORF1ab/nsp31326P1326LcCtcTt6969AY.40.000107
ORF1ab/nsp31326P1326LcCtcTt5454B.1.617.20.000203
ORF1ab/nsp31326P1326LcCtcTt4141B.1.1.4340.014291
ORF1ab/nsp31326P1326LcCtcTt3636AY.430.000159
ORF1ab/nsp31326P1326LcCtcTt3434AY.690.006347
ORF1ab/nsp31326P1326LcCtcTt3030Q.20.018405
ORF1ab/nsp31326P1326LcCtcTt2727AY.250.000162
ORF1ab/nsp31326P1326LcCtcTt2121B.1.360.003064
ORF1ab/nsp31326P1326LcCtcTt1919AY.390.00047
ORF1ab/nsp31326P1326LcCtcTt1919B.1.1770.00025
ORF1ab/nsp31326P1326LcCtcTt1818B.1.20.000158
ORF1ab/nsp31326P1326LcCtcTt1818D.20.001351
ORF1ab/nsp31326P1326LcCtcTt1717AY.1020.000451
ORF1ab/nsp31326P1326LcCtcTt1616AY.30.000159
ORF1ab/nsp31326P1326LcCtcTt1515B.1.2400.003233
ORF1ab/nsp31326P1326LcCtcTt1414AY.1030.000087
ORF1ab/nsp31326P1326LcCtcTt1414B.1.1.700.004775
ORF1ab/nsp31326P1326LcCtcTt1414B.1.110.30.010057
ORF1ab/nsp31326P1326LcCtcTt1414B.1.36.290.007243
ORF1ab/nsp31326P1326LcCtcTt1212B.1.1600.000374
ORF1ab/nsp31326P1326LcCtcTt1111AY.98.10.000533
ORF1ab/nsp31326P1326LcCtcTt1111B.1.5170.004697
ORF1ab/nsp31326P1326LcCtcTt1111P.20.002053
ORF1ab/nsp31326P1326LcCtcTt1010B.550.029499
ORF1ab/nsp31326P1326LcCtcTt99AY.39.10.000357
ORF1ab/nsp31326P1326LcCtcTt99B.1.1.470.048128
ORF1ab/nsp31326P1326LcCtcTt88AE.80.003912
ORF1ab/nsp31326P1326LcCtcTt88AY.440.000049
ORF1ab/nsp31326P1326LcCtcTt88B.1.6141
ORF1ab/nsp31326P1326LcCtcTt77AY.610.000733
ORF1ab/nsp31326P1326LcCtcTt77B0.000895
ORF1ab/nsp31326P1326LcCtcTt77B.1.2100.014925
ORF1ab/nsp31326P1326LcCtcTt77B.1.2340.000924
ORF1ab/nsp31326P1326LcCtcTt77B.270.107692
ORF1ab/nsp31326P1326LcCtcTt66AY.9.20.00022
ORF1ab/nsp31326P1326LcCtcTt55AY.50.000103
ORF1ab/nsp31326P1326LcCtcTt55B.1.4290.000118
ORF1ab/nsp31326P1326LcCtcTt55P.1.140.000239
ORF1ab/nsp31326P1326LcCtcTt44AY.1190.000141
ORF1ab/nsp31326P1326LcCtcTt44AY.230.000279
ORF1ab/nsp31326P1326LcCtcTt44AY.530.00115
ORF1ab/nsp31326P1326LcCtcTt44B.1.177.430.005908
ORF1ab/nsp31326P1326LcCtcTt44B.1.5260.000094
ORF1ab/nsp31326P1326LcCtcTt44P.10.000063
ORF1ab/nsp31326P1326LcCtcTt33AY.270.000194
ORF1ab/nsp31326P1326LcCtcTt33AY.4.20.000065
ORF1ab/nsp31326P1326LcCtcTt33AY.450.000365
ORF1ab/nsp31326P1326LcCtcTt33AY.46.60.000217
ORF1ab/nsp31326P1326LcCtcTt33AY.75.10.000541
ORF1ab/nsp31326P1326LcCtcTt33B.1.1.2140.000166
ORF1ab/nsp31326P1326LcCtcTt33B.1.1.2220.000612
ORF1ab/nsp31326P1326LcCtcTt33B.1.1.330.001263
ORF1ab/nsp31326P1326LcCtcTt33B.1.1.5190.000119
ORF1ab/nsp31326P1326LcCtcTt33B.1.438.10.000322
ORF1ab/nsp31326P1326LcCtcTt33B.1.5950.000783
ORF1ab/nsp31326P1326LcCtcTt33B.1.5960.000261
ORF1ab/nsp31326P1326LcCtcTt33B.1.6210.000266
ORF1ab/nsp31326P1326LcCtcTt33C.140.012987
ORF1ab/nsp31326P1326LcCtcTt22A.10.000564
ORF1ab/nsp31326P1326LcCtcTt22AY.1140.000462
ORF1ab/nsp31326P1326LcCtcTt22AY.1200.000074
ORF1ab/nsp31326P1326LcCtcTt22AY.16.10.00094
ORF1ab/nsp31326P1326LcCtcTt22AY.240.000862
ORF1ab/nsp31326P1326LcCtcTt22AY.3.10.000171
ORF1ab/nsp31326P1326LcCtcTt22AY.420.00008
ORF1ab/nsp31326P1326LcCtcTt22AY.460.000208
ORF1ab/nsp31326P1326LcCtcTt22AY.590.001059
ORF1ab/nsp31326P1326LcCtcTt22AY.60.000082
ORF1ab/nsp31326P1326LcCtcTt22AY.740.000231
ORF1ab/nsp31326P1326LcCtcTt22AY.750.000112
ORF1ab/nsp31326P1326LcCtcTt22AZ.50.007018
ORF1ab/nsp31326P1326LcCtcTt22B.1.1.390.001019
ORF1ab/nsp31326P1326LcCtcTt22B.1.1.3980.006452
ORF1ab/nsp31326P1326LcCtcTt22B.1.1.5260.007092
ORF1ab/nsp31326P1326LcCtcTt22B.1.1570.00597
ORF1ab/nsp31326P1326LcCtcTt22B.1.177.210.000153
ORF1ab/nsp31326P1326LcCtcTt22B.1.2210.000142
ORF1ab/nsp31326P1326LcCtcTt22B.1.36.170.000988
ORF1ab/nsp31326P1326LcCtcTt22B.1.4530.006472
ORF1ab/nsp31326P1326LcCtcTt22B.1.466.20.000782
ORF1ab/nsp31326P1326LcCtcTt22B.1.5680.002222
ORF1ab/nsp31326P1326LcCtcTt22B.1.5760.001813
ORF1ab/nsp31326P1326LcCtcTt22Q.80.00033
ORF1ab/nsp31326P1326LcCtcTt11A.30.002096
ORF1ab/nsp31326P1326LcCtcTt11A.50.001923
ORF1ab/nsp31326P1326LcCtcTt11AN.10.02
ORF1ab/nsp31326P1326LcCtcTt11AW.10.003049
ORF1ab/nsp31326P1326LcCtcTt11AY.1000.000046
ORF1ab/nsp31326P1326LcCtcTt11AY.1110.000183
ORF1ab/nsp31326P1326LcCtcTt11AY.1160.000287
ORF1ab/nsp31326P1326LcCtcTt11AY.1170.000085
ORF1ab/nsp31326P1326LcCtcTt11AY.120.10.000321
ORF1ab/nsp31326P1326LcCtcTt11AY.140.000088
ORF1ab/nsp31326P1326LcCtcTt11AY.200.000039
ORF1ab/nsp31326P1326LcCtcTt11AY.290.000016
ORF1ab/nsp31326P1326LcCtcTt11AY.330.000067
ORF1ab/nsp31326P1326LcCtcTt11AY.340.000097
ORF1ab/nsp31326P1326LcCtcTt11AY.360.000148
ORF1ab/nsp31326P1326LcCtcTt11AY.380.000499
ORF1ab/nsp31326P1326LcCtcTt11AY.4.2.10.000149
ORF1ab/nsp31326P1326LcCtcTt11AY.46.40.000165
ORF1ab/nsp31326P1326LcCtcTt11AY.470.000031
ORF1ab/nsp31326P1326LcCtcTt11AY.480.000465
ORF1ab/nsp31326P1326LcCtcTt11AY.5.40.000277
ORF1ab/nsp31326P1326LcCtcTt11AY.830.001724
ORF1ab/nsp31326P1326LcCtcTt11AY.850.000427
ORF1ab/nsp31326P1326LcCtcTt11AY.99.20.000092
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.10.000327
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.1210.002427
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.1610.003534
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.1700.001247
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.2770.000759
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.280.000311
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.2940.001266
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.3060.000438
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.3260.001761
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.4090.002833
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.4320.001266
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.4640.001473
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.4860.001577
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.5140.038462
ORF1ab/nsp31326P1326LcCtcTt11B.1.1.5210.005348
ORF1ab/nsp31326P1326LcCtcTt11B.1.1670.007812
ORF1ab/nsp31326P1326LcCtcTt11B.1.177.100.000878
ORF1ab/nsp31326P1326LcCtcTt11B.1.177.150.000631
ORF1ab/nsp31326P1326LcCtcTt11B.1.177.160.000664
ORF1ab/nsp31326P1326LcCtcTt11B.1.177.200.001517
ORF1ab/nsp31326P1326LcCtcTt11B.1.177.310.011494
ORF1ab/nsp31326P1326LcCtcTt11B.1.177.440.000519
ORF1ab/nsp31326P1326LcCtcTt11B.1.177.560.000668
ORF1ab/nsp31326P1326LcCtcTt11B.1.177.570.000281
ORF1ab/nsp31326P1326LcCtcTt11B.1.177.70.000165
ORF1ab/nsp31326P1326LcCtcTt11B.1.177.810.000189
ORF1ab/nsp31326P1326LcCtcTt11B.1.177.860.000183
ORF1ab/nsp31326P1326LcCtcTt11B.1.2230.002778
ORF1ab/nsp31326P1326LcCtcTt11B.1.2360.002053
ORF1ab/nsp31326P1326LcCtcTt11B.1.2380.014925
ORF1ab/nsp31326P1326LcCtcTt11B.1.258.210.007752
ORF1ab/nsp31326P1326LcCtcTt11B.1.258.30.001675
ORF1ab/nsp31326P1326LcCtcTt11B.1.3110.000275
ORF1ab/nsp31326P1326LcCtcTt11B.1.3290.000608
ORF1ab/nsp31326P1326LcCtcTt11B.1.3380.008621
ORF1ab/nsp31326P1326LcCtcTt11B.1.350.008475
ORF1ab/nsp31326P1326LcCtcTt11B.1.3510.00003
ORF1ab/nsp31326P1326LcCtcTt11B.1.351.50.0006
ORF1ab/nsp31326P1326LcCtcTt11B.1.3570.009524
ORF1ab/nsp31326P1326LcCtcTt11B.1.36.180.00042
ORF1ab/nsp31326P1326LcCtcTt11B.1.36.20.010753
ORF1ab/nsp31326P1326LcCtcTt11B.1.36.370.002778
ORF1ab/nsp31326P1326LcCtcTt11B.1.3830.009009
ORF1ab/nsp31326P1326LcCtcTt11B.1.3960.000706
ORF1ab/nsp31326P1326LcCtcTt11B.1.4040.001302
ORF1ab/nsp31326P1326LcCtcTt11B.1.416.10.001563
ORF1ab/nsp31326P1326LcCtcTt11B.1.4930.025641
ORF1ab/nsp31326P1326LcCtcTt11B.1.5250.000113
ORF1ab/nsp31326P1326LcCtcTt11B.1.5380.008065
ORF1ab/nsp31326P1326LcCtcTt11B.1.575.10.002439
ORF1ab/nsp31326P1326LcCtcTt11B.1.5820.000491
ORF1ab/nsp31326P1326LcCtcTt11B.1.6090.000479
ORF1ab/nsp31326P1326LcCtcTt11B.1.621.10.000506
ORF1ab/nsp31326P1326LcCtcTt11B.1.6250.002353
ORF1ab/nsp31326P1326LcCtcTt11B.1.6280.000352
ORF1ab/nsp31326P1326LcCtcTt11B.1.6320.006711
ORF1ab/nsp31326P1326LcCtcTt11B.1.930.000934
ORF1ab/nsp31326P1326LcCtcTt11B.400.000364
ORF1ab/nsp31326P1326LcCtcTt11C.1.20.004255
ORF1ab/nsp31326P1326LcCtcTt11C.350.000774
ORF1ab/nsp31326P1326LcCtcTt11C.370.000116
ORF1ab/nsp31326P1326LcCtcTt11D.50.004975
ORF1ab/nsp31326P1326LcCtcTt11L.30.003546
ORF1ab/nsp31326P1326LcCtcTt11P.1.70.000319
ORF1ab/nsp31326P1326LcCtcTt11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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