CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = P109L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3109P109LP927LnonsyncCacTa803580330.9997513044-3046
ORF1ab/nsp3109P109LP927LnonsynCCaTTa803520.0002489113044-3046

Details of the mutation P109L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3109P109LcCacTa80338035All0.001536
ORF1ab/nsp3109P109LCCaTTa28035All0
ORF1ab/nsp3109P109LcCacTa15171517B.1.1.70.001358
ORF1ab/nsp3109P109LcCacTa899899B.1.617.20.003385
ORF1ab/nsp3109P109LcCacTa789789AY.250.004746
ORF1ab/nsp3109P109LcCacTa419419AY.40.000652
ORF1ab/nsp3109P109LcCacTa298298B.1.5770.204811
ORF1ab/nsp3109P109LcCacTa284284AY.1030.001763
ORF1ab/nsp3109P109LcCacTa282282AY.430.001249
ORF1ab/nsp3109P109LcCacTa264264AY.440.001607
ORF1ab/nsp3109P109LcCacTa174174AY.30.001731
ORF1ab/nsp3109P109LcCacTa165165AY.9.20.00606
ORF1ab/nsp3109P109LcCacTa158158AY.390.003904
ORF1ab/nsp3109P109LcCacTa134134B.1.1770.001764
ORF1ab/nsp3109P109LcCacTa124124AY.1090.091716
ORF1ab/nsp3109P109LcCacTa112112P.10.001764
ORF1ab/nsp3109P109LcCacTa109109AY.1020.00289
ORF1ab/nsp3109P109LcCacTa107107B.1.20.000942
ORF1ab/nsp3109P109LcCacTa104104B.10.000953
ORF1ab/nsp3109P109LcCacTa101101B.1.10.001832
ORF1ab/nsp3109P109LcCacTa9797AY.880.085765
ORF1ab/nsp3109P109LcCacTa8787AY.260.002463
ORF1ab/nsp3109P109LcCacTa7878AY.5.10.293233
ORF1ab/nsp3109P109LcCacTa7070AY.610.007334
ORF1ab/nsp3109P109LcCacTa6666B.1.5260.001551
ORF1ab/nsp3109P109LcCacTa4949B.1.177.630.132432
ORF1ab/nsp3109P109LcCacTa4747B.1.6210.00416
ORF1ab/nsp3109P109LcCacTa4646AY.200.001788
ORF1ab/nsp3109P109LcCacTa4646B.1.2840.605263
ORF1ab/nsp3109P109LcCacTa4545AY.50.000929
ORF1ab/nsp3109P109LcCacTa4444AY.4.20.000954
ORF1ab/nsp3109P109LcCacTa4141R.10.00369
ORF1ab/nsp3109P109LcCacTa3939AY.116.10.012146
ORF1ab/nsp3109P109LcCacTa3838B.1.2340.005014
ORF1ab/nsp3109P109LcCacTa3232AY.470.000995
ORF1ab/nsp3109P109LcCacTa3131B.1.438.10.003325
ORF1ab/nsp3109P109LcCacTa3030B.1.1600.000936
ORF1ab/nsp3109P109LcCacTa3030B.1.4290.000706
ORF1ab/nsp3109P109LcCacTa2929AY.420.001167
ORF1ab/nsp3109P109LcCacTa2929B.1.1.2140.001608
ORF1ab/nsp3109P109LcCacTa2828AY.750.001569
ORF1ab/nsp3109P109LcCacTa2525B.1.1.5190.000993
ORF1ab/nsp3109P109LcCacTa2323B.1.36.220.027778
ORF1ab/nsp3109P109LcCacTa2222AY.1190.000777
ORF1ab/nsp3109P109LcCacTa2020AE.40.869565
ORF1ab/nsp3109P109LcCacTa2020AY.46.60.001444
ORF1ab/nsp3109P109LcCacTa1818B.1.1.3180.005432
ORF1ab/nsp3109P109LcCacTa1717P.1.140.000813
ORF1ab/nsp3109P109LcCacTa1515AY.1170.001268
ORF1ab/nsp3109P109LcCacTa1515AY.290.000237
ORF1ab/nsp3109P109LcCacTa1515AY.980.001185
ORF1ab/nsp3109P109LcCacTa1515AY.99.20.001382
ORF1ab/nsp3109P109LcCacTa1515B.1.177.440.007784
ORF1ab/nsp3109P109LcCacTa1414AY.1000.000644
ORF1ab/nsp3109P109LcCacTa1414AY.1130.001993
ORF1ab/nsp3109P109LcCacTa1414AY.1200.000521
ORF1ab/nsp3109P109LcCacTa1414B.1.177.690.020772
ORF1ab/nsp3109P109LcCacTa1414B.1.2210.000994
ORF1ab/nsp3109P109LcCacTa1414B.1.2430.000974
ORF1ab/nsp3109P109LcCacTa1313AY.460.001353
ORF1ab/nsp3109P109LcCacTa1313AY.920.003735
ORF1ab/nsp3109P109LcCacTa1212AY.39.10.000475
ORF1ab/nsp3109P109LcCacTa1111AY.300.004353
ORF1ab/nsp3109P109LcCacTa1111B.1.1.3480.008758
ORF1ab/nsp3109P109LcCacTa1111B.1.1.3970.024775
ORF1ab/nsp3109P109LcCacTa1111B.1.177.600.002403
ORF1ab/nsp3109P109LcCacTa1111B.1.5170.004697
ORF1ab/nsp3109P109LcCacTa1010AY.370.003161
ORF1ab/nsp3109P109LcCacTa1010AY.75.10.001803
ORF1ab/nsp3109P109LcCacTa1010B.1.3110.002746
ORF1ab/nsp3109P109LcCacTa1010B.1.5960.000871
ORF1ab/nsp3109P109LcCacTa99AY.230.000628
ORF1ab/nsp3109P109LcCacTa99AY.270.000582
ORF1ab/nsp3109P109LcCacTa99B.1.1.2220.001836
ORF1ab/nsp3109P109LcCacTa99B.1.1470.006803
ORF1ab/nsp3109P109LcCacTa99B.1.5250.001018
ORF1ab/nsp3109P109LcCacTa99B.1.910.018672
ORF1ab/nsp3109P109LcCacTa88AY.120.002528
ORF1ab/nsp3109P109LcCacTa88AY.340.000776
ORF1ab/nsp3109P109LcCacTa78AY.9.10.000586
ORF1ab/nsp3109P109LCCaTTa18AY.9.10.000084
ORF1ab/nsp3109P109LcCacTa88B.1.1.4320.010127
ORF1ab/nsp3109P109LcCacTa88B.1.2400.001725
ORF1ab/nsp3109P109LcCacTa88B.1.360.001167
ORF1ab/nsp3109P109LcCacTa88B.440.8
ORF1ab/nsp3109P109LcCacTa88Q.70.008889
ORF1ab/nsp3109P109LcCacTa77AY.120.20.008997
ORF1ab/nsp3109P109LcCacTa77AY.530.002013
ORF1ab/nsp3109P109LcCacTa77AY.540.000667
ORF1ab/nsp3109P109LcCacTa77C.370.000812
ORF1ab/nsp3109P109LcCacTa77Q.30.001015
ORF1ab/nsp3109P109LcCacTa66AY.1180.000376
ORF1ab/nsp3109P109LcCacTa66AY.130.000966
ORF1ab/nsp3109P109LcCacTa66AY.190.006842
ORF1ab/nsp3109P109LcCacTa66AY.5.40.00166
ORF1ab/nsp3109P109LcCacTa66B.1.177.350.004147
ORF1ab/nsp3109P109LcCacTa66B.1.3510.000178
ORF1ab/nsp3109P109LcCacTa66D.20.00045
ORF1ab/nsp3109P109LcCacTa55AH.30.019011
ORF1ab/nsp3109P109LcCacTa55AY.330.000334
ORF1ab/nsp3109P109LcCacTa55AY.98.10.000242
ORF1ab/nsp3109P109LcCacTa55B.1.1.2840.000537
ORF1ab/nsp3109P109LcCacTa55B.1.1.890.030303
ORF1ab/nsp3109P109LcCacTa55B.1.177.820.002387
ORF1ab/nsp3109P109LcCacTa55B.1.2580.000333
ORF1ab/nsp3109P109LcCacTa55B.1.4990.005252
ORF1ab/nsp3109P109LcCacTa55N.40.021277
ORF1ab/nsp3109P109LcCacTa55P.1.120.00242
ORF1ab/nsp3109P109LcCacTa55Q.80.000825
ORF1ab/nsp3109P109LcCacTa44AY.1140.000924
ORF1ab/nsp3109P109LcCacTa44AY.140.000352
ORF1ab/nsp3109P109LcCacTa44AY.4.50.00043
ORF1ab/nsp3109P109LcCacTa44AY.450.000487
ORF1ab/nsp3109P109LcCacTa44AY.46.40.000658
ORF1ab/nsp3109P109LcCacTa44AY.7.10.000451
ORF1ab/nsp3109P109LcCacTa44AY.90.00027
ORF1ab/nsp3109P109LcCacTa44B.1.1.2050.01487
ORF1ab/nsp3109P109LcCacTa44B.1.1.500.002716
ORF1ab/nsp3109P109LcCacTa44B.1.110.30.002874
ORF1ab/nsp3109P109LcCacTa44B.1.177.620.004768
ORF1ab/nsp3109P109LcCacTa44B.1.177.810.000757
ORF1ab/nsp3109P109LcCacTa44B.1.36.210.008639
ORF1ab/nsp3109P109LcCacTa44B.1.617.10.000516
ORF1ab/nsp3109P109LcCacTa44Q.10.000505
ORF1ab/nsp3109P109LcCacTa33A.2.50.001497
ORF1ab/nsp3109P109LcCacTa33AY.120.10.000963
ORF1ab/nsp3109P109LcCacTa33AY.1210.000406
ORF1ab/nsp3109P109LcCacTa33AY.360.000445
ORF1ab/nsp3109P109LcCacTa33AY.690.00056
ORF1ab/nsp3109P109LcCacTa33AY.99.10.004658
ORF1ab/nsp3109P109LcCacTa33B.1.1.3160.002775
ORF1ab/nsp3109P109LcCacTa33B.1.1.3420.1875
ORF1ab/nsp3109P109LcCacTa33B.1.1.4480.006098
ORF1ab/nsp3109P109LcCacTa33B.1.1.510.005155
ORF1ab/nsp3109P109LcCacTa33B.1.177.730.001699
ORF1ab/nsp3109P109LcCacTa33B.1.2790.001541
ORF1ab/nsp3109P109LcCacTa33B.1.4280.003061
ORF1ab/nsp3109P109LcCacTa33B.1.4970.000944
ORF1ab/nsp3109P109LcCacTa33B.1.6180.012097
ORF1ab/nsp3109P109LcCacTa33C.360.002732
ORF1ab/nsp3109P109LcCacTa33P.1.150.000697
ORF1ab/nsp3109P109LcCacTa33P.1.170.000485
ORF1ab/nsp3109P109LcCacTa33P.70.0131
ORF1ab/nsp3109P109LcCacTa22AY.100.00106
ORF1ab/nsp3109P109LcCacTa22AY.1110.000366
ORF1ab/nsp3109P109LcCacTa22AY.1160.000574
ORF1ab/nsp3109P109LcCacTa22AY.320.001065
ORF1ab/nsp3109P109LcCacTa22AY.550.001835
ORF1ab/nsp3109P109LcCacTa22AY.70.000392
ORF1ab/nsp3109P109LcCacTa22AY.7.20.001119
ORF1ab/nsp3109P109LcCacTa22AY.740.000231
ORF1ab/nsp3109P109LcCacTa22AY.790.002421
ORF1ab/nsp3109P109LcCacTa22AY.80.001212
ORF1ab/nsp3109P109LcCacTa22AY.900.001369
ORF1ab/nsp3109P109LcCacTa22AY.990.002099
ORF1ab/nsp3109P109LcCacTa22AZ.10.001735
ORF1ab/nsp3109P109LcCacTa22B.1.1.10.000653
ORF1ab/nsp3109P109LcCacTa22B.1.1.2070.002364
ORF1ab/nsp3109P109LcCacTa22B.1.1.2300.018349
ORF1ab/nsp3109P109LcCacTa22B.1.1.3120.003824
ORF1ab/nsp3109P109LcCacTa22B.1.1.3170.000823
ORF1ab/nsp3109P109LcCacTa22B.1.1.3720.001377
ORF1ab/nsp3109P109LcCacTa22B.1.1.3850.008929
ORF1ab/nsp3109P109LcCacTa22B.1.1.390.001019
ORF1ab/nsp3109P109LcCacTa22B.1.1.4340.000697
ORF1ab/nsp3109P109LcCacTa22B.1.160.70.004158
ORF1ab/nsp3109P109LcCacTa22B.1.177.240.002591
ORF1ab/nsp3109P109LcCacTa22B.1.177.500.00939
ORF1ab/nsp3109P109LcCacTa22B.1.177.70.00033
ORF1ab/nsp3109P109LcCacTa22B.1.177.860.000367
ORF1ab/nsp3109P109LcCacTa22B.1.214.20.001199
ORF1ab/nsp3109P109LcCacTa22B.1.2220.003384
ORF1ab/nsp3109P109LcCacTa22B.1.2320.001075
ORF1ab/nsp3109P109LcCacTa22B.1.2980.004228
ORF1ab/nsp3109P109LcCacTa22B.1.36.80.002
ORF1ab/nsp3109P109LcCacTa22B.1.3690.00057
ORF1ab/nsp3109P109LcCacTa22B.1.4260.002018
ORF1ab/nsp3109P109LcCacTa22B.1.4270.000101
ORF1ab/nsp3109P109LcCacTa22B.1.466.20.000782
ORF1ab/nsp3109P109LcCacTa22B.1.5610.000794
ORF1ab/nsp3109P109LcCacTa22B.1.5950.000522
ORF1ab/nsp3109P109LcCacTa22B.1.6090.000959
ORF1ab/nsp3109P109LcCacTa22B.1.6280.000705
ORF1ab/nsp3109P109LcCacTa22B.1.6360.013423
ORF1ab/nsp3109P109LcCacTa22B.1.6370.000146
ORF1ab/nsp3109P109LcCacTa22C.160.002121
ORF1ab/nsp3109P109LcCacTa22N.50.003534
ORF1ab/nsp3109P109LcCacTa11A.2.20.001689
ORF1ab/nsp3109P109LcCacTa11AD.20.000219
ORF1ab/nsp3109P109LcCacTa11AE.80.000489
ORF1ab/nsp3109P109LcCacTa11AS.10.009524
ORF1ab/nsp3109P109LCCaTTa11AY.1050.000643
ORF1ab/nsp3109P109LcCacTa11AY.1060.000335
ORF1ab/nsp3109P109LcCacTa11AY.1070.000466
ORF1ab/nsp3109P109LcCacTa11AY.110.001339
ORF1ab/nsp3109P109LcCacTa11AY.1100.000113
ORF1ab/nsp3109P109LcCacTa11AY.120.2.10.000498
ORF1ab/nsp3109P109LcCacTa11AY.160.00038
ORF1ab/nsp3109P109LcCacTa11AY.280.00189
ORF1ab/nsp3109P109LcCacTa11AY.3.10.000085
ORF1ab/nsp3109P109LcCacTa11AY.350.000233
ORF1ab/nsp3109P109LcCacTa11AY.380.000499
ORF1ab/nsp3109P109LcCacTa11AY.4.2.10.000149
ORF1ab/nsp3109P109LcCacTa11AY.46.50.000198
ORF1ab/nsp3109P109LcCacTa11AY.5.30.000337
ORF1ab/nsp3109P109LcCacTa11AY.590.00053
ORF1ab/nsp3109P109LcCacTa11AY.680.000274
ORF1ab/nsp3109P109LcCacTa11AY.710.000475
ORF1ab/nsp3109P109LcCacTa11AY.770.001127
ORF1ab/nsp3109P109LcCacTa11AY.780.001541
ORF1ab/nsp3109P109LcCacTa11AY.800.001129
ORF1ab/nsp3109P109LcCacTa11AY.840.000437
ORF1ab/nsp3109P109LcCacTa11AY.850.000427
ORF1ab/nsp3109P109LcCacTa11AY.870.000833
ORF1ab/nsp3109P109LcCacTa11AY.930.000273
ORF1ab/nsp3109P109LcCacTa11AZ.20.000821
ORF1ab/nsp3109P109LcCacTa11B0.000128
ORF1ab/nsp3109P109LcCacTa11B.1.1.1700.001247
ORF1ab/nsp3109P109LcCacTa11B.1.1.1980.001468
ORF1ab/nsp3109P109LcCacTa11B.1.1.2160.00089
ORF1ab/nsp3109P109LcCacTa11B.1.1.250.000569
ORF1ab/nsp3109P109LcCacTa11B.1.1.2530.002506
ORF1ab/nsp3109P109LcCacTa11B.1.1.2770.000759
ORF1ab/nsp3109P109LcCacTa11B.1.1.280.000311
ORF1ab/nsp3109P109LcCacTa11B.1.1.2860.002899
ORF1ab/nsp3109P109LcCacTa11B.1.1.2890.002083
ORF1ab/nsp3109P109LcCacTa11B.1.1.2940.001266
ORF1ab/nsp3109P109LcCacTa11B.1.1.3050.003861
ORF1ab/nsp3109P109LcCacTa11B.1.1.3060.000438
ORF1ab/nsp3109P109LcCacTa11B.1.1.3320.03125
ORF1ab/nsp3109P109LcCacTa11B.1.1.3640.066667
ORF1ab/nsp3109P109LcCacTa11B.1.1.370.000193
ORF1ab/nsp3109P109LcCacTa11B.1.1.3980.003226
ORF1ab/nsp3109P109LcCacTa11B.1.1.4200.001006
ORF1ab/nsp3109P109LcCacTa11B.1.1.4400.011765
ORF1ab/nsp3109P109LcCacTa11B.1.1.700.000341
ORF1ab/nsp3109P109LcCacTa11B.1.1.710.006061
ORF1ab/nsp3109P109LcCacTa11B.1.1110.001175
ORF1ab/nsp3109P109LcCacTa11B.1.1120.005181
ORF1ab/nsp3109P109LcCacTa11B.1.177.100.000878
ORF1ab/nsp3109P109LcCacTa11B.1.177.120.000152
ORF1ab/nsp3109P109LcCacTa11B.1.177.150.000631
ORF1ab/nsp3109P109LcCacTa11B.1.177.160.000664
ORF1ab/nsp3109P109LcCacTa11B.1.177.170.000821
ORF1ab/nsp3109P109LcCacTa11B.1.177.190.001431
ORF1ab/nsp3109P109LcCacTa11B.1.177.330.001645
ORF1ab/nsp3109P109LcCacTa11B.1.177.40.000211
ORF1ab/nsp3109P109LcCacTa11B.1.177.410.0025
ORF1ab/nsp3109P109LcCacTa11B.1.177.480.003125
ORF1ab/nsp3109P109LcCacTa11B.1.177.790.002342
ORF1ab/nsp3109P109LcCacTa11B.1.177.80.000752
ORF1ab/nsp3109P109LcCacTa11B.1.2180.005155
ORF1ab/nsp3109P109LcCacTa11B.1.2190.009434
ORF1ab/nsp3109P109LcCacTa11B.1.2370.004975
ORF1ab/nsp3109P109LcCacTa11B.1.258.170.000104
ORF1ab/nsp3109P109LcCacTa11B.1.3190.003049
ORF1ab/nsp3109P109LcCacTa11B.1.3480.018182
ORF1ab/nsp3109P109LcCacTa11B.1.351.20.000303
ORF1ab/nsp3109P109LcCacTa11B.1.3560.001727
ORF1ab/nsp3109P109LcCacTa11B.1.36.10.00114
ORF1ab/nsp3109P109LcCacTa11B.1.36.100.004785
ORF1ab/nsp3109P109LcCacTa11B.1.36.180.00042
ORF1ab/nsp3109P109LcCacTa11B.1.36.280.005747
ORF1ab/nsp3109P109LcCacTa11B.1.36.290.000517
ORF1ab/nsp3109P109LcCacTa11B.1.3990.001934
ORF1ab/nsp3109P109LcCacTa11B.1.4040.001302
ORF1ab/nsp3109P109LcCacTa11B.1.4090.000781
ORF1ab/nsp3109P109LcCacTa11B.1.4160.001269
ORF1ab/nsp3109P109LcCacTa11B.1.4360.001029
ORF1ab/nsp3109P109LcCacTa11B.1.4700.001404
ORF1ab/nsp3109P109LcCacTa11B.1.5230.002451
ORF1ab/nsp3109P109LcCacTa11B.1.5380.008065
ORF1ab/nsp3109P109LcCacTa11B.1.5430.01
ORF1ab/nsp3109P109LcCacTa11B.1.5640.000426
ORF1ab/nsp3109P109LcCacTa11B.1.5760.000907
ORF1ab/nsp3109P109LcCacTa11B.1.595.40.007299
ORF1ab/nsp3109P109LcCacTa11B.1.6230.000536
ORF1ab/nsp3109P109LcCacTa11B.1.6260.005714
ORF1ab/nsp3109P109LcCacTa11B.1.9.40.006135
ORF1ab/nsp3109P109LcCacTa11B.400.000364
ORF1ab/nsp3109P109LcCacTa11B.60.00091
ORF1ab/nsp3109P109LcCacTa11P.1.10.000318
ORF1ab/nsp3109P109LcCacTa11P.1.20.001156
ORF1ab/nsp3109P109LcCacTa11P.1.40.000977
ORF1ab/nsp3109P109LcCacTa11P.1.90.004808
ORF1ab/nsp3109P109LcCacTa11P.20.000187
ORF1ab/nsp3109P109LcCacTa11P.30.001595
ORF1ab/nsp3109P109LcCacTa11Z.10.00289

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.