CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = P108P

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3108P108PP926PsynccTccC4563480.7631583041-3043
ORF1ab/nsp3108P108PP926PsynccTccG456690.1513163041-3043
ORF1ab/nsp3108P108PP926PsynccTccA456390.08552633041-3043

Details of the mutation P108P within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3108P108PccTccC348456All0.000067
ORF1ab/nsp3108P108PccTccG69456All0.000013
ORF1ab/nsp3108P108PccTccA39456All0.000007
ORF1ab/nsp3108P108PccTccG3281B.1.1.70.000029
ORF1ab/nsp3108P108PccTccC3181B.1.1.70.000028
ORF1ab/nsp3108P108PccTccA1881B.1.1.70.000016
ORF1ab/nsp3108P108PccTccC6565AY.40.000101
ORF1ab/nsp3108P108PccTccC6263AY.1030.000385
ORF1ab/nsp3108P108PccTccG163AY.1030.000006
ORF1ab/nsp3108P108PccTccC3839D.20.002852
ORF1ab/nsp3108P108PccTccA139D.20.000075
ORF1ab/nsp3108P108PccTccC2023B.1.617.20.000075
ORF1ab/nsp3108P108PccTccG323B.1.617.20.000011
ORF1ab/nsp3108P108PccTccA1117AY.390.000272
ORF1ab/nsp3108P108PccTccC517AY.390.000124
ORF1ab/nsp3108P108PccTccG117AY.390.000025
ORF1ab/nsp3108P108PccTccC1116P.10.000173
ORF1ab/nsp3108P108PccTccG516P.10.000079
ORF1ab/nsp3108P108PccTccC1515AY.800.01693
ORF1ab/nsp3108P108PccTccC1112AY.470.000342
ORF1ab/nsp3108P108PccTccG112AY.470.000031
ORF1ab/nsp3108P108PccTccC910AY.440.000055
ORF1ab/nsp3108P108PccTccA110AY.440.000006
ORF1ab/nsp3108P108PccTccC79B.1.20.000062
ORF1ab/nsp3108P108PccTccA29B.1.20.000018
ORF1ab/nsp3108P108PccTccC88AY.39.20.012327
ORF1ab/nsp3108P108PccTccC67AY.1020.000159
ORF1ab/nsp3108P108PccTccG17AY.1020.000027
ORF1ab/nsp3108P108PccTccC56B.10.000046
ORF1ab/nsp3108P108PccTccG16B.10.000009
ORF1ab/nsp3108P108PccTccC66B.1.1770.000079
ORF1ab/nsp3108P108PccTccG66B.1.5950.001566
ORF1ab/nsp3108P108PccTccG66P.20.00112
ORF1ab/nsp3108P108PccTccC44AY.290.000063
ORF1ab/nsp3108P108PccTccC24AY.30.00002
ORF1ab/nsp3108P108PccTccA24AY.30.00002
ORF1ab/nsp3108P108PccTccG34AY.4.50.000322
ORF1ab/nsp3108P108PccTccC14AY.4.50.000107
ORF1ab/nsp3108P108PccTccC44AY.50.000083
ORF1ab/nsp3108P108PccTccG44AY.530.00115
ORF1ab/nsp3108P108PccTccC34B.1.10.000054
ORF1ab/nsp3108P108PccTccG14B.1.10.000018
ORF1ab/nsp3108P108PccTccC44B.1.1.5190.000159
ORF1ab/nsp3108P108PccTccC12AY.250.000006
ORF1ab/nsp3108P108PccTccA12AY.250.000006
ORF1ab/nsp3108P108PccTccC22AY.260.000057
ORF1ab/nsp3108P108PccTccG22B.1.1.280.000622
ORF1ab/nsp3108P108PccTccC22B.1.4290.000047
ORF1ab/nsp3108P108PccTccC22B.1.5260.000047
ORF1ab/nsp3108P108PccTccC110.055556
ORF1ab/nsp3108P108PccTccC11A.10.000282
ORF1ab/nsp3108P108PccTccA11A.23.10.000704
ORF1ab/nsp3108P108PccTccC11AY.190.00114
ORF1ab/nsp3108P108PccTccA11AY.200.000039
ORF1ab/nsp3108P108PccTccG11AY.270.000065
ORF1ab/nsp3108P108PccTccC11AY.360.000148
ORF1ab/nsp3108P108PccTccC11AY.4.20.000022
ORF1ab/nsp3108P108PccTccC11AY.4.40.000409
ORF1ab/nsp3108P108PccTccC11AY.610.000105
ORF1ab/nsp3108P108PccTccG11AY.70.000196
ORF1ab/nsp3108P108PccTccC11AY.750.000056
ORF1ab/nsp3108P108PccTccC11AY.790.001211
ORF1ab/nsp3108P108PccTccC11B.1.1.1740.003378
ORF1ab/nsp3108P108PccTccC11B.1.1.2800.003086
ORF1ab/nsp3108P108PccTccC11B.1.177.440.000519
ORF1ab/nsp3108P108PccTccC11B.1.177.460.000918
ORF1ab/nsp3108P108PccTccC11B.1.2410.000812
ORF1ab/nsp3108P108PccTccC11B.1.3490.000715
ORF1ab/nsp3108P108PccTccC11B.1.3510.00003
ORF1ab/nsp3108P108PccTccA11B.1.351.30.000876
ORF1ab/nsp3108P108PccTccC11B.1.4110.003704
ORF1ab/nsp3108P108PccTccC11B.1.4260.001009
ORF1ab/nsp3108P108PccTccC11B.1.4660.023256
ORF1ab/nsp3108P108PccTccC11B.1.6090.000479
ORF1ab/nsp3108P108PccTccC11B.1.619.10.000641
ORF1ab/nsp3108P108PccTccC11B.1.621.10.000506
ORF1ab/nsp3108P108PccTccC11B.400.000364
ORF1ab/nsp3108P108PccTccC11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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