CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = N51S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp351N51SN869SnonsynaAtaGt7767720.9948452870-2872
ORF1ab/nsp351N51SN869SnonsynAATTCA77620.002577322870-2872
ORF1ab/nsp351N51SN869SnonsynAAtTCt77620.002577322870-2872

Details of the mutation N51S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp351N51SaAtaGt772776All0.000148
ORF1ab/nsp351N51SAAtTCt2776All0
ORF1ab/nsp351N51SAATTCA2776All0
ORF1ab/nsp351N51SaAtaGt370370B.1.1.4171
ORF1ab/nsp351N51SaAtaGt219219B.1.1.3480.174363
ORF1ab/nsp351N51SaAtaGt1717P.10.000268
ORF1ab/nsp351N51SaAtaGt1515B.1.1.70.000013
ORF1ab/nsp351N51SaAtaGt1515B.1.5260.000353
ORF1ab/nsp351N51SaAtaGt1111AY.260.000311
ORF1ab/nsp351N51SaAtaGt1010AY.1190.000353
ORF1ab/nsp351N51SaAtaGt1010AY.40.000016
ORF1ab/nsp351N51SaAtaGt1010B.1.10.000181
ORF1ab/nsp351N51SaAtaGt99B.1.617.20.000034
ORF1ab/nsp351N51SaAtaGt88B.10.000073
ORF1ab/nsp351N51SaAtaGt48B.1.1770.000053
ORF1ab/nsp351N51SAAtTCt28B.1.1770.000026
ORF1ab/nsp351N51SAATTCA28B.1.1770.000026
ORF1ab/nsp351N51SaAtaGt55AY.1030.000031
ORF1ab/nsp351N51SaAtaGt55AY.250.00003
ORF1ab/nsp351N51SaAtaGt55B.1.1.500.003394
ORF1ab/nsp351N51SaAtaGt55B.1.2430.000348
ORF1ab/nsp351N51SaAtaGt55B.1.617.10.000645
ORF1ab/nsp351N51SaAtaGt44AY.430.000018
ORF1ab/nsp351N51SaAtaGt33B.1.20.000026
ORF1ab/nsp351N51SaAtaGt22AY.1020.000053
ORF1ab/nsp351N51SaAtaGt22AY.60.000082
ORF1ab/nsp351N51SaAtaGt22AY.750.000112
ORF1ab/nsp351N51SaAtaGt22AY.90.000135
ORF1ab/nsp351N51SaAtaGt22B.1.1.700.000682
ORF1ab/nsp351N51SaAtaGt22B.1.2210.000142
ORF1ab/nsp351N51SaAtaGt22B.1.6370.000146
ORF1ab/nsp351N51SaAtaGt11AY.1000.000046
ORF1ab/nsp351N51SaAtaGt11AY.190.00114
ORF1ab/nsp351N51SaAtaGt11AY.20.000356
ORF1ab/nsp351N51SaAtaGt11AY.200.000039
ORF1ab/nsp351N51SaAtaGt11AY.270.000065
ORF1ab/nsp351N51SaAtaGt11AY.290.000016
ORF1ab/nsp351N51SaAtaGt11AY.30.00001
ORF1ab/nsp351N51SaAtaGt11AY.34.10.00051
ORF1ab/nsp351N51SaAtaGt11AY.39.20.001541
ORF1ab/nsp351N51SaAtaGt11AY.420.00004
ORF1ab/nsp351N51SaAtaGt11AY.440.000006
ORF1ab/nsp351N51SaAtaGt11AY.510.000909
ORF1ab/nsp351N51SaAtaGt11AY.870.000833
ORF1ab/nsp351N51SaAtaGt11AY.980.000079
ORF1ab/nsp351N51SaAtaGt11B.1.1.1570.000913
ORF1ab/nsp351N51SaAtaGt11B.1.1.1740.003378
ORF1ab/nsp351N51SaAtaGt11B.1.1.4160.000905
ORF1ab/nsp351N51SaAtaGt11B.1.177.860.000183
ORF1ab/nsp351N51SaAtaGt11B.1.3490.000715
ORF1ab/nsp351N51SaAtaGt11B.1.360.000146
ORF1ab/nsp351N51SaAtaGt11B.1.4290.000024
ORF1ab/nsp351N51SaAtaGt11B.1.4560.003268
ORF1ab/nsp351N51SaAtaGt11B.1.621.10.000506
ORF1ab/nsp351N51SaAtaGt11B.110.005128
ORF1ab/nsp351N51SaAtaGt11B.390.002331
ORF1ab/nsp351N51SaAtaGt11C.36.10.004149
ORF1ab/nsp351N51SaAtaGt11P.1.10.000318
ORF1ab/nsp351N51SaAtaGt11P.1.140.000048

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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