CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = N1680D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31680N1680DN2498DnonsynAatGat56550.9821437757-7759
ORF1ab/nsp31680N1680DN2498DnonsynAaTGaC5610.01785717757-7759

Details of the mutation N1680D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31680N1680DAatGat5556All0.000011
ORF1ab/nsp31680N1680DAaTGaC156All0
ORF1ab/nsp31680N1680DAatGat1111B.1.1.70.00001
ORF1ab/nsp31680N1680DAatGat45AY.30.00004
ORF1ab/nsp31680N1680DAaTGaC15AY.30.00001
ORF1ab/nsp31680N1680DAatGat55AY.40.000008
ORF1ab/nsp31680N1680DAatGat33A.23.10.002113
ORF1ab/nsp31680N1680DAatGat33AY.250.000018
ORF1ab/nsp31680N1680DAatGat33B.1.1.5190.000119
ORF1ab/nsp31680N1680DAatGat22AY.34.10.00102
ORF1ab/nsp31680N1680DAatGat22AY.430.000009
ORF1ab/nsp31680N1680DAatGat22AY.650.001066
ORF1ab/nsp31680N1680DAatGat22B.1.110.30.001437
ORF1ab/nsp31680N1680DAatGat22B.1.20.000018
ORF1ab/nsp31680N1680DAatGat11AY.1020.000027
ORF1ab/nsp31680N1680DAatGat11AY.1190.000035
ORF1ab/nsp31680N1680DAatGat11AY.1200.000037
ORF1ab/nsp31680N1680DAatGat11AY.290.000016
ORF1ab/nsp31680N1680DAatGat11AY.3.10.000085
ORF1ab/nsp31680N1680DAatGat11AY.750.000056
ORF1ab/nsp31680N1680DAatGat11AY.98.10.000048
ORF1ab/nsp31680N1680DAatGat11B.10.000009
ORF1ab/nsp31680N1680DAatGat11B.1.10.000018
ORF1ab/nsp31680N1680DAatGat11B.1.1.2790.001121
ORF1ab/nsp31680N1680DAatGat11B.1.1770.000013
ORF1ab/nsp31680N1680DAatGat11B.1.177.640.090909
ORF1ab/nsp31680N1680DAatGat11B.1.258.170.000104
ORF1ab/nsp31680N1680DAatGat11B.1.351.30.000876
ORF1ab/nsp31680N1680DAatGat11B.1.3560.001727
ORF1ab/nsp31680N1680DAatGat11B.1.4110.003704

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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