CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = M768I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3768M768IM1586InonsynatGatA1061268640.6468155021-5023
ORF1ab/nsp3768M768IM1586InonsynatGatT1061237090.349515021-5023
ORF1ab/nsp3768M768IM1586InonsynatGatC10612390.003675085021-5023

Details of the mutation M768I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3768M768IatGatA686410612All0.001313
ORF1ab/nsp3768M768IatGatT370910612All0.000709
ORF1ab/nsp3768M768IatGatC3910612All0.000007
ORF1ab/nsp3768M768IatGatA66736673Q.30.967803
ORF1ab/nsp3768M768IatGatT11821195AY.430.005237
ORF1ab/nsp3768M768IatGatA131195AY.430.000058
ORF1ab/nsp3768M768IatGatT556556B.1.177.520.977153
ORF1ab/nsp3768M768IatGatT343449B.1.1.70.000307
ORF1ab/nsp3768M768IatGatA97449B.1.1.70.000087
ORF1ab/nsp3768M768IatGatC9449B.1.1.70.000008
ORF1ab/nsp3768M768IatGatT337340AY.440.002051
ORF1ab/nsp3768M768IatGatA3340AY.440.000018
ORF1ab/nsp3768M768IatGatT158163B.1.617.20.000595
ORF1ab/nsp3768M768IatGatA5163B.1.617.20.000019
ORF1ab/nsp3768M768IatGatT119133AY.40.000185
ORF1ab/nsp3768M768IatGatA14133AY.40.000022
ORF1ab/nsp3768M768IatGatT8790B.1.20.000766
ORF1ab/nsp3768M768IatGatA290B.1.20.000018
ORF1ab/nsp3768M768IatGatC190B.1.20.000009
ORF1ab/nsp3768M768IatGatT7777Y.10.987179
ORF1ab/nsp3768M768IatGatT7176B.1.1770.000935
ORF1ab/nsp3768M768IatGatC376B.1.1770.00004
ORF1ab/nsp3768M768IatGatA276B.1.1770.000026
ORF1ab/nsp3768M768IatGatT7676B.1.5260.001786
ORF1ab/nsp3768M768IatGatT4949AY.1020.001299
ORF1ab/nsp3768M768IatGatT3639AY.1030.000224
ORF1ab/nsp3768M768IatGatA339AY.1030.000019
ORF1ab/nsp3768M768IatGatT3637AY.390.00089
ORF1ab/nsp3768M768IatGatA137AY.390.000025
ORF1ab/nsp3768M768IatGatT3232AY.30.000318
ORF1ab/nsp3768M768IatGatT3131AY.1130.004414
ORF1ab/nsp3768M768IatGatT2731AY.250.000162
ORF1ab/nsp3768M768IatGatA431AY.250.000024
ORF1ab/nsp3768M768IatGatT2630B.10.000238
ORF1ab/nsp3768M768IatGatA430B.10.000037
ORF1ab/nsp3768M768IatGatT2828P.10.000441
ORF1ab/nsp3768M768IatGatT2022AY.260.000566
ORF1ab/nsp3768M768IatGatA222AY.260.000057
ORF1ab/nsp3768M768IatGatT1919AY.70.003724
ORF1ab/nsp3768M768IatGatC1518AY.90.001014
ORF1ab/nsp3768M768IatGatT218AY.90.000135
ORF1ab/nsp3768M768IatGatA118AY.90.000068
ORF1ab/nsp3768M768IatGatT1515B.1.1.5190.000596
ORF1ab/nsp3768M768IatGatT1414AY.1210.001894
ORF1ab/nsp3768M768IatGatT1414AY.50.000289
ORF1ab/nsp3768M768IatGatT1414B.1.2430.000974
ORF1ab/nsp3768M768IatGatT1213AY.200.000466
ORF1ab/nsp3768M768IatGatA113AY.200.000039
ORF1ab/nsp3768M768IatGatT813B.1.10.000145
ORF1ab/nsp3768M768IatGatA413B.1.10.000073
ORF1ab/nsp3768M768IatGatC113B.1.10.000018
ORF1ab/nsp3768M768IatGatT1212AY.1000.000552
ORF1ab/nsp3768M768IatGatT1011B.1.3510.000297
ORF1ab/nsp3768M768IatGatC111B.1.3510.00003
ORF1ab/nsp3768M768IatGatT1011B.1.4290.000235
ORF1ab/nsp3768M768IatGatA111B.1.4290.000024
ORF1ab/nsp3768M768IatGatT1010B.1.160.200.089286
ORF1ab/nsp3768M768IatGatT99AY.1170.000761
ORF1ab/nsp3768M768IatGatT99AY.4.50.000967
ORF1ab/nsp3768M768IatGatT68AY.60.000247
ORF1ab/nsp3768M768IatGatC18AY.60.000041
ORF1ab/nsp3768M768IatGatA18AY.60.000041
ORF1ab/nsp3768M768IatGatT88AY.610.000838
ORF1ab/nsp3768M768IatGatT88AY.9.10.00067
ORF1ab/nsp3768M768IatGatT88B.1.1.330.003367
ORF1ab/nsp3768M768IatGatT77AY.1190.000247
ORF1ab/nsp3768M768IatGatT77AY.750.000392
ORF1ab/nsp3768M768IatGatT77B.1.3690.001997
ORF1ab/nsp3768M768IatGatT77B.1.4040.009115
ORF1ab/nsp3768M768IatGatT77B.1.5610.002779
ORF1ab/nsp3768M768IatGatT77B.1.5960.00061
ORF1ab/nsp3768M768IatGatT56AY.9.20.000184
ORF1ab/nsp3768M768IatGatC16AY.9.20.000037
ORF1ab/nsp3768M768IatGatT66B.1.1.2510.047619
ORF1ab/nsp3768M768IatGatT56B.1.1.2840.000537
ORF1ab/nsp3768M768IatGatA16B.1.1.2840.000107
ORF1ab/nsp3768M768IatGatT46B.1.1600.000125
ORF1ab/nsp3768M768IatGatA26B.1.1600.000062
ORF1ab/nsp3768M768IatGatT66C.370.000696
ORF1ab/nsp3768M768IatGatT55AE.10.056818
ORF1ab/nsp3768M768IatGatT55AY.140.00044
ORF1ab/nsp3768M768IatGatT35AY.290.000047
ORF1ab/nsp3768M768IatGatA25AY.290.000032
ORF1ab/nsp3768M768IatGatT55AY.420.000201
ORF1ab/nsp3768M768IatGatA45AY.460.000416
ORF1ab/nsp3768M768IatGatT15AY.460.000104
ORF1ab/nsp3768M768IatGatT45AY.75.10.000721
ORF1ab/nsp3768M768IatGatC15AY.75.10.00018
ORF1ab/nsp3768M768IatGatT55Q.60.033113
ORF1ab/nsp3768M768IatGatT44AY.1110.000733
ORF1ab/nsp3768M768IatGatT44AY.360.000593
ORF1ab/nsp3768M768IatGatT44AY.450.000487
ORF1ab/nsp3768M768IatGatT44AY.780.006163
ORF1ab/nsp3768M768IatGatT34B.1.1.3060.001315
ORF1ab/nsp3768M768IatGatA14B.1.1.3060.000438
ORF1ab/nsp3768M768IatGatA44B.1.1.3480.003185
ORF1ab/nsp3768M768IatGatT44P.1.140.000191
ORF1ab/nsp3768M768IatGatT23AY.330.000134
ORF1ab/nsp3768M768IatGatC13AY.330.000067
ORF1ab/nsp3768M768IatGatT33AY.340.000291
ORF1ab/nsp3768M768IatGatT33AY.410.000882
ORF1ab/nsp3768M768IatGatT23AY.470.000062
ORF1ab/nsp3768M768IatGatA13AY.470.000031
ORF1ab/nsp3768M768IatGatT23AY.98.10.000097
ORF1ab/nsp3768M768IatGatC13AY.98.10.000048
ORF1ab/nsp3768M768IatGatT33AY.99.20.000276
ORF1ab/nsp3768M768IatGatT33B.1.1.250.001706
ORF1ab/nsp3768M768IatGatT33B.1.36.170.001482
ORF1ab/nsp3768M768IatGatT23B.1.4270.000101
ORF1ab/nsp3768M768IatGatC13B.1.4270.00005
ORF1ab/nsp3768M768IatGatT33D.20.000225
ORF1ab/nsp3768M768IatGatA33P.1.150.000697
ORF1ab/nsp3768M768IatGatT33P.1.70.000958
ORF1ab/nsp3768M768IatGatA220.111111
ORF1ab/nsp3768M768IatGatA22A.2.5.10.009615
ORF1ab/nsp3768M768IatGatT22AE.80.000978
ORF1ab/nsp3768M768IatGatT22AY.1200.000074
ORF1ab/nsp3768M768IatGatC12AY.4.20.000022
ORF1ab/nsp3768M768IatGatT12AY.4.20.000022
ORF1ab/nsp3768M768IatGatT22AY.4.2.10.000298
ORF1ab/nsp3768M768IatGatT22AY.590.001059
ORF1ab/nsp3768M768IatGatT22AY.80.001212
ORF1ab/nsp3768M768IatGatT22B.1.1.280.000622
ORF1ab/nsp3768M768IatGatT22B.1.1.3110.000716
ORF1ab/nsp3768M768IatGatT22B.1.177.40.000422
ORF1ab/nsp3768M768IatGatT22B.1.2340.000264
ORF1ab/nsp3768M768IatGatT22B.1.2580.000133
ORF1ab/nsp3768M768IatGatT22B.1.360.000292
ORF1ab/nsp3768M768IatGatT22B.1.36.20.021505
ORF1ab/nsp3768M768IatGatT22B.1.4440.031746
ORF1ab/nsp3768M768IatGatT22C.350.001548
ORF1ab/nsp3768M768IatGatT22Q.10.000253
ORF1ab/nsp3768M768IatGatT12Q.40.000455
ORF1ab/nsp3768M768IatGatA12Q.40.000455
ORF1ab/nsp3768M768IatGatA22R.10.00018
ORF1ab/nsp3768M768IatGatT11A.2.20.001689
ORF1ab/nsp3768M768IatGatT11A.250.018182
ORF1ab/nsp3768M768IatGatT11AD.20.000219
ORF1ab/nsp3768M768IatGatT11AY.1050.000643
ORF1ab/nsp3768M768IatGatT11AY.1090.00074
ORF1ab/nsp3768M768IatGatT11AY.1180.000063
ORF1ab/nsp3768M768IatGatA11AY.160.00038
ORF1ab/nsp3768M768IatGatT11AY.230.00007
ORF1ab/nsp3768M768IatGatA11AY.3.10.000085
ORF1ab/nsp3768M768IatGatT11AY.320.000532
ORF1ab/nsp3768M768IatGatT11AY.380.000499
ORF1ab/nsp3768M768IatGatT11AY.46.60.000072
ORF1ab/nsp3768M768IatGatT11AY.480.000465
ORF1ab/nsp3768M768IatGatC11AY.540.000095
ORF1ab/nsp3768M768IatGatT11AY.650.000533
ORF1ab/nsp3768M768IatGatT11AY.7.10.000113
ORF1ab/nsp3768M768IatGatT11AY.700.000209
ORF1ab/nsp3768M768IatGatT11AY.740.000116
ORF1ab/nsp3768M768IatGatT11AY.870.000833
ORF1ab/nsp3768M768IatGatT11AY.910.00073
ORF1ab/nsp3768M768IatGatT11AZ.20.000821
ORF1ab/nsp3768M768IatGatT11AZ.50.003509
ORF1ab/nsp3768M768IatGatT11B.1.1.10.000327
ORF1ab/nsp3768M768IatGatT11B.1.1.1010.01
ORF1ab/nsp3768M768IatGatT11B.1.1.2070.001182
ORF1ab/nsp3768M768IatGatT11B.1.1.2170.003636
ORF1ab/nsp3768M768IatGatT11B.1.1.2610.008621
ORF1ab/nsp3768M768IatGatT11B.1.1.3260.001761
ORF1ab/nsp3768M768IatGatT11B.1.1.4090.002833
ORF1ab/nsp3768M768IatGatA11B.1.1.4480.002033
ORF1ab/nsp3768M768IatGatT11B.1.1.500.000679
ORF1ab/nsp3768M768IatGatT11B.1.1.700.000341
ORF1ab/nsp3768M768IatGatT11B.1.1.950.019608
ORF1ab/nsp3768M768IatGatC11B.1.1.970.029412
ORF1ab/nsp3768M768IatGatA11B.1.1280.000635
ORF1ab/nsp3768M768IatGatT11B.1.177.440.000519
ORF1ab/nsp3768M768IatGatT11B.1.177.570.000281
ORF1ab/nsp3768M768IatGatT11B.1.177.60.000977
ORF1ab/nsp3768M768IatGatT11B.1.230.006061
ORF1ab/nsp3768M768IatGatT11B.1.2390.001221
ORF1ab/nsp3768M768IatGatT11B.1.3500.002933
ORF1ab/nsp3768M768IatGatT11B.1.36.290.000517
ORF1ab/nsp3768M768IatGatT11B.1.3960.000706
ORF1ab/nsp3768M768IatGatT11B.1.4000.000429
ORF1ab/nsp3768M768IatGatA11B.1.415.10.007576
ORF1ab/nsp3768M768IatGatT11B.1.466.20.000391
ORF1ab/nsp3768M768IatGatT11B.1.4700.001404
ORF1ab/nsp3768M768IatGatT11B.1.5250.000113
ORF1ab/nsp3768M768IatGatT11B.1.5380.008065
ORF1ab/nsp3768M768IatGatT11B.1.5580.004566
ORF1ab/nsp3768M768IatGatA11B.1.5650.00081
ORF1ab/nsp3768M768IatGatT11B.1.5750.000303
ORF1ab/nsp3768M768IatGatA11B.1.5760.000907
ORF1ab/nsp3768M768IatGatT11B.1.5950.000261
ORF1ab/nsp3768M768IatGatT11B.1.6140.125
ORF1ab/nsp3768M768IatGatT11B.1.617.10.000129
ORF1ab/nsp3768M768IatGatT11B.1.6210.000089
ORF1ab/nsp3768M768IatGatA11B.570.015152
ORF1ab/nsp3768M768IatGatT11C.360.000911
ORF1ab/nsp3768M768IatGatT11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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